{"id":"https://openalex.org/W2014766124","doi":"https://doi.org/10.1016/0264-410x(93)90068-9","title":"Testosterone impairs efficacy of protective vaccination against P. chabaudi malaria","display_name":"Testosterone impairs efficacy of protective vaccination against P. chabaudi malaria","publication_year":1993,"publication_date":"1993-01-01","ids":{"openalex":"https://openalex.org/W2014766124","doi":"https://doi.org/10.1016/0264-410x(93)90068-9","mag":"2014766124","pmid":"https://pubmed.ncbi.nlm.nih.gov/8249427"},"language":"en","primary_location":{"id":"doi:10.1016/0264-410x(93)90068-9","doi":"https://doi.org/10.1016/0264-410x(93)90068-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0264-410x(93)90068-9","pdf_url":null,"source":{"id":"https://openalex.org/S27359860","display_name":"Vaccine","issn_l":"0264-410X","issn":["0264-410X","1873-2518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072937215","display_name":"Frank Thomas Wunderlich","orcid":"https://orcid.org/0000-0002-9209-3501","observed_orcids":["https://orcid.org/0000-0002-9209-3501"]},"institutions":[{"id":"https://openalex.org/I44260953","display_name":"Heinrich Heine University D\u00fcsseldorf","ror":"https://ror.org/024z2rq82","country_code":"DE","type":"education","lineage":["https://openalex.org/I44260953"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"F. Wunderlich","raw_affiliation_strings":["Division of Parasitology, Heinrich-Heine-University, D\u00fcsseldorf, Germany","Division of Parasitology, Institute of Zoology, Heinrich-Heine-University, Universit\u00e4tsstr. 1, 4000 D\u00fcsseldorf 1, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Parasitology, Heinrich-Heine-University, D\u00fcsseldorf, Germany","institution_ids":["https://openalex.org/I44260953"]},{"raw_affiliation_string":"Division of Parasitology, Institute of Zoology, Heinrich-Heine-University, Universit\u00e4tsstr. 1, 4000 D\u00fcsseldorf 1, Germany","institution_ids":["https://openalex.org/I44260953"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049537228","display_name":"W. Maurin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I44260953","display_name":"Heinrich Heine University D\u00fcsseldorf","ror":"https://ror.org/024z2rq82","country_code":"DE","type":"education","lineage":["https://openalex.org/I44260953"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"W. Maurin","raw_affiliation_strings":["Division of Parasitology, Institute of Zoology, Heinrich-Heine-University, Universit\u00e4tsstr. 1, 4000 D\u00fcsseldorf 1, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Parasitology, Institute of Zoology, Heinrich-Heine-University, Universit\u00e4tsstr. 1, 4000 D\u00fcsseldorf 1, Germany","institution_ids":["https://openalex.org/I44260953"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038449118","display_name":"W. Peter M. Benten","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I44260953","display_name":"Heinrich Heine University D\u00fcsseldorf","ror":"https://ror.org/024z2rq82","country_code":"DE","type":"education","lineage":["https://openalex.org/I44260953"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"W.P.M. Benten","raw_affiliation_strings":["Division of Parasitology, Institute of Zoology, Heinrich-Heine-University, Universit\u00e4tsstr. 1, 4000 D\u00fcsseldorf 1, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Parasitology, Institute of Zoology, Heinrich-Heine-University, Universit\u00e4tsstr. 1, 4000 D\u00fcsseldorf 1, Germany","institution_ids":["https://openalex.org/I44260953"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110103053","display_name":"Hans-Peter Schmitt-Wrede","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I44260953","display_name":"Heinrich Heine University D\u00fcsseldorf","ror":"https://ror.org/024z2rq82","country_code":"DE","type":"education","lineage":["https://openalex.org/I44260953"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"H.-P. Schmitt-Wrede","raw_affiliation_strings":["Division of Parasitology, Institute of Zoology, Heinrich-Heine-University, Universit\u00e4tsstr. 1, 4000 D\u00fcsseldorf 1, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Parasitology, Institute of Zoology, Heinrich-Heine-University, Universit\u00e4tsstr. 1, 4000 D\u00fcsseldorf 1, Germany","institution_ids":["https://openalex.org/I44260953"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5072937215"],"corresponding_institution_ids":["https://openalex.org/I44260953"],"apc_list":{"value":3620,"currency":"USD","value_usd":3620},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"11","issue":"11","first_page":"1097","last_page":"1099"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13410","display_name":"Immune responses and vaccinations","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/testosterone","display_name":"testosterone","score":0.7689999938011169},{"id":"https://openalex.org/keywords/plasmodium-chabaudi","display_name":"Plasmodium chabaudi","score":0.9200000166893005},{"id":"https://openalex.org/keywords/malaria-vaccine","display_name":"malaria vaccine","score":0.8640000224113464},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.5899999737739563},{"id":"https://openalex.org/keywords/vaccine-efficacy","display_name":"vaccine efficacy","score":0.5609999895095825},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.6259999871253967},{"id":"https://openalex.org/keywords/host-immune-response","display_name":"host immune response","score":0.6240000128746033},{"id":"https://openalex.org/keywords/b10-a-mice","display_name":"B10.A mice","score":0.722000002861023}],"concepts":[{"id":"https://openalex.org/C2780789526","wikidata":"https://www.wikidata.org/wiki/Q7201860","display_name":"Plasmodium chabaudi","level":5,"score":0.9554287195205688},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.8009682893753052},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.7880022525787354},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.75016850233078},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6574550867080688},{"id":"https://openalex.org/C2781034427","wikidata":"https://www.wikidata.org/wiki/Q6741353","display_name":"Malaria vaccine","level":4,"score":0.4787446856498718},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.4572538733482361},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4514467120170593},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4505052864551544},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.33677375316619873},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3284503221511841},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28577160835266113},{"id":"https://openalex.org/C2775867548","wikidata":"https://www.wikidata.org/wiki/Q1897162","display_name":"Parasitemia","level":4,"score":0.1621297299861908},{"id":"https://openalex.org/C2778371730","wikidata":"https://www.wikidata.org/wiki/Q311383","display_name":"Plasmodium falciparum","level":3,"score":0.12932872772216797}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004347","descriptor_name":"Drug Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004910","descriptor_name":"Erythrocyte Membrane","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000469","qualifier_name":"parasitology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008288","descriptor_name":"Malaria","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008288","descriptor_name":"Malaria","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008815","descriptor_name":"Mice, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012727","descriptor_name":"Sex Characteristics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013739","descriptor_name":"Testosterone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013739","descriptor_name":"Testosterone","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014611","descriptor_name":"Vaccination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016788","descriptor_name":"Plasmodium chabaudi","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D017780","descriptor_name":"Malaria Vaccines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0264-410x(93)90068-9","doi":"https://doi.org/10.1016/0264-410x(93)90068-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0264-410x(93)90068-9","pdf_url":null,"source":{"id":"https://openalex.org/S27359860","display_name":"Vaccine","issn_l":"0264-410X","issn":["0264-410X","1873-2518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"journal-article"},{"id":"pmid:8249427","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8249427","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1908008679","https://openalex.org/W1982844410","https://openalex.org/W1992637352","https://openalex.org/W1994112095","https://openalex.org/W2032538337","https://openalex.org/W2041142645","https://openalex.org/W2046123379","https://openalex.org/W2066386932","https://openalex.org/W2068984744","https://openalex.org/W2080694854","https://openalex.org/W2154693416","https://openalex.org/W2239043818","https://openalex.org/W2460975629","https://openalex.org/W6718178536"],"related_works":["https://openalex.org/W2049973318","https://openalex.org/W2053689426","https://openalex.org/W1986009664","https://openalex.org/W1968038275","https://openalex.org/W4411029623","https://openalex.org/W2955201651","https://openalex.org/W794073962","https://openalex.org/W1972340424","https://openalex.org/W2119591013","https://openalex.org/W1450011739"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}