{"id":"https://openalex.org/W2014565764","doi":"https://doi.org/10.1007/bf02602566","title":"An intragenic polymorphism in the human tumor necrosis factor alpha (TNFA) chain-encoding gene","display_name":"An intragenic polymorphism in the human tumor necrosis factor alpha (TNFA) chain-encoding gene","publication_year":1996,"publication_date":"1996-07-01","ids":{"openalex":"https://openalex.org/W2014565764","doi":"https://doi.org/10.1007/bf02602566","mag":"2014565764","pmid":"https://pubmed.ncbi.nlm.nih.gov/8815046"},"language":"en","primary_location":{"id":"doi:10.1007/bf02602566","doi":"https://doi.org/10.1007/bf02602566","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02602566","pdf_url":null,"source":{"id":"https://openalex.org/S62103174","display_name":"Immunogenetics","issn_l":"0093-7711","issn":["0093-7711","1432-1211"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunogenetics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011286489","display_name":"Sandra D\u2019Alfonso","orcid":"https://orcid.org/0000-0002-3983-9925","observed_orcids":["https://orcid.org/0000-0002-3983-9925"]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Sandra D'Alfonso","raw_affiliation_strings":["Dipartimento di Scienze Mediche, Universita' di Torino, Novara, Italy","Centro CNR Immunogenetica ed Oncologia Sperimentale, Torino, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Scienze Mediche, Universita' di Torino, Novara, Italy","institution_ids":["https://openalex.org/I55143463"]},{"raw_affiliation_string":"Centro CNR Immunogenetica ed Oncologia Sperimentale, Torino, Italy","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111701468","display_name":"PatriciaMomigliano Richiardi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Patricia Momigliano Richiardi","raw_affiliation_strings":["Centro CNR Immunogenetica ed Oncologia Sperimentale, Torino, Italy","Dipartimento di Scienze Mediche, Universita' di Torino, Via Solarole 17, 28100, Novara, Italy","Dipartimento di Scienze Mediche, Universita' di Torino, Novara, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro CNR Immunogenetica ed Oncologia Sperimentale, Torino, Italy","institution_ids":[]},{"raw_affiliation_string":"Dipartimento di Scienze Mediche, Universita' di Torino, Via Solarole 17, 28100, Novara, Italy","institution_ids":["https://openalex.org/I55143463"]},{"raw_affiliation_string":"Dipartimento di Scienze Mediche, Universita' di Torino, Novara, Italy","institution_ids":["https://openalex.org/I55143463"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I55143463"],"apc_list":{"value":2890,"currency":"USD","value_usd":2890},"apc_paid":null,"fwci":0.5996,"has_fulltext":false,"cited_by_count":38,"citation_normalized_percentile":{"value":0.68107759,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"44","issue":"4","first_page":"321","last_page":"322"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.826200008392334,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.826200008392334,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.05779999867081642,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.01940000057220459,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9710000157356262},{"id":"https://openalex.org/keywords/intragenic-polymorphisms","display_name":"intragenic polymorphisms","score":0.9890000224113464},{"id":"https://openalex.org/keywords/genetic-variation","display_name":"genetic variation","score":0.6370000243186951},{"id":"https://openalex.org/keywords/gene-structure","display_name":"gene structure","score":0.38499999046325684}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8316836357116699},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.7181038856506348},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.7053808569908142},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6272874474525452},{"id":"https://openalex.org/C149737253","wikidata":"https://www.wikidata.org/wiki/Q3240252","display_name":"Polymorphism (computer science)","level":4,"score":0.5426530838012695},{"id":"https://openalex.org/C47042493","wikidata":"https://www.wikidata.org/wiki/Q265799","display_name":"Human genetics","level":3,"score":0.4770911633968353},{"id":"https://openalex.org/C152204938","wikidata":"https://www.wikidata.org/wiki/Q4735158","display_name":"Alpha chain","level":3,"score":0.42828643321990967},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3312283158302307},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.31078118085861206},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.22852399945259094}],"mesh":[{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011110","descriptor_name":"Polymorphism, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017931","descriptor_name":"DNA Primers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018895","descriptor_name":"Microsatellite Repeats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf02602566","doi":"https://doi.org/10.1007/bf02602566","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf02602566","pdf_url":null,"source":{"id":"https://openalex.org/S62103174","display_name":"Immunogenetics","issn_l":"0093-7711","issn":["0093-7711","1432-1211"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunogenetics","raw_type":"journal-article"},{"id":"pmid:8815046","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8815046","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunogenetics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":3,"referenced_works":["https://openalex.org/W2091852263","https://openalex.org/W2113405278","https://openalex.org/W2165737225"],"related_works":["https://openalex.org/W2039394334","https://openalex.org/W2006722829","https://openalex.org/W2031178654","https://openalex.org/W2079134359","https://openalex.org/W794952637","https://openalex.org/W2308949106","https://openalex.org/W1993160550","https://openalex.org/W1997420372","https://openalex.org/W2063520263","https://openalex.org/W2419447384"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}