{"id":"https://openalex.org/W2014540348","doi":"https://doi.org/10.1002/j.1536-4801.2004.tb00863.x","title":"Immunogenicity and Safety of an Inactivated Hepatitis A Vaccine in Children With Down Syndrome","display_name":"Immunogenicity and Safety of an Inactivated Hepatitis A Vaccine in Children With Down Syndrome","publication_year":2004,"publication_date":"2004-09-23","ids":{"openalex":"https://openalex.org/W2014540348","doi":"https://doi.org/10.1002/j.1536-4801.2004.tb00863.x","mag":"2014540348","pmid":"https://pubmed.ncbi.nlm.nih.gov/15448421"},"language":"en","primary_location":{"id":"doi:10.1002/j.1536-4801.2004.tb00863.x","doi":"https://doi.org/10.1002/j.1536-4801.2004.tb00863.x","is_oa":true,"landing_page_url":"https://doi.org/10.1002/j.1536-4801.2004.tb00863.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.1536-4801.2004.tb00863.x","source":{"id":"https://openalex.org/S197964821","display_name":"Journal of Pediatric Gastroenterology and Nutrition","issn_l":"0277-2116","issn":["0277-2116","1536-4801"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pediatric Gastroenterology and Nutrition","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.1536-4801.2004.tb00863.x","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077027593","display_name":"Cristina Targa Ferreira","orcid":"https://orcid.org/0000-0002-9899-9478","observed_orcids":["https://orcid.org/0000-0002-9899-9478"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]},{"id":"https://openalex.org/I4210097146","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210097146"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Cristina Targa Ferreira","raw_affiliation_strings":["Pediatric Gastroenterology School of Medicine Universidade Federal do Rio Grande do Sul (UFRGS) Porto Alegre Brazil","Pediatric Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre, School of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. ctf@webflash.com.br"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric Gastroenterology School of Medicine Universidade Federal do Rio Grande do Sul (UFRGS) Porto Alegre Brazil","institution_ids":["https://openalex.org/I130442723"]},{"raw_affiliation_string":"Pediatric Gastroenterology, Hospital de Cl\u00ednicas de Porto Alegre, School of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. ctf@webflash.com.br","institution_ids":["https://openalex.org/I130442723","https://openalex.org/I4210097146"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027780339","display_name":"J\u00falio C\u00e9sar Loguercio Leite","orcid":"https://orcid.org/0000-0002-3551-6811","observed_orcids":["https://orcid.org/0000-0002-3551-6811"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]},{"id":"https://openalex.org/I4210097146","display_name":"Hospital de Cl\u00ednicas de Porto Alegre","ror":"https://ror.org/010we4y38","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210097146"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"J\u00falio C\u00e9sar Leite","raw_affiliation_strings":["Genetics Division of Hospital de Cl\u00ednicas de Porto Alegre School of Medicine Universidade Federal do Rio Grande do Sul (UFRGS) Porto Alegre Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics Division of Hospital de Cl\u00ednicas de Porto Alegre School of Medicine Universidade Federal do Rio Grande do Sul (UFRGS) Porto Alegre Brazil","institution_ids":["https://openalex.org/I130442723","https://openalex.org/I4210097146"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023914031","display_name":"Adriano Nori Rodrigues Taniguchi","orcid":"https://orcid.org/0000-0001-8182-7103","observed_orcids":["https://orcid.org/0000-0001-8182-7103"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Adriano Taniguchi","raw_affiliation_strings":["Pediatric Gastroenterology School of Medicine Universidade Federal do Rio Grande do Sul (UFRGS) Porto Alegre Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric Gastroenterology School of Medicine Universidade Federal do Rio Grande do Sul (UFRGS) Porto Alegre Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041408628","display_name":"Sandra Maria Gon\u00e7alves Vieira","orcid":"https://orcid.org/0000-0002-9788-5428","observed_orcids":["https://orcid.org/0000-0002-9788-5428"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Sandra Maria Vieira","raw_affiliation_strings":["Pediatric Gastroenterology School of Medicine Universidade Federal do Rio Grande do Sul (UFRGS) Porto Alegre Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric Gastroenterology School of Medicine Universidade Federal do Rio Grande do Sul (UFRGS) Porto Alegre Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091257068","display_name":"Jorge Pereira\u2010Lima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Jorge Pereira\u2010Lima","raw_affiliation_strings":["Pediatric Gastroenterology School of Medicine Universidade Federal do Rio Grande do Sul (UFRGS) Porto Alegre Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric Gastroenterology School of Medicine Universidade Federal do Rio Grande do Sul (UFRGS) Porto Alegre Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059405802","display_name":"Themis Reverbel da Silveira","orcid":"https://orcid.org/0000-0001-9867-8650","observed_orcids":["https://orcid.org/0000-0001-9867-8650"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Themis Reverbel da Silveira","raw_affiliation_strings":["Pediatric Gastroenterology School of Medicine Universidade Federal do Rio Grande do Sul (UFRGS) Porto Alegre Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric Gastroenterology School of Medicine Universidade Federal do Rio Grande do Sul (UFRGS) Porto Alegre Brazil","institution_ids":["https://openalex.org/I130442723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5077027593"],"corresponding_institution_ids":["https://openalex.org/I130442723","https://openalex.org/I4210097146"],"apc_list":{"value":3780,"currency":"USD","value_usd":3780},"apc_paid":null,"fwci":1.1796,"has_fulltext":true,"cited_by_count":38,"citation_normalized_percentile":{"value":0.80077987,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"39","issue":"4","first_page":"337","last_page":"340"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12025","display_name":"Hepatitis Viruses Studies and Epidemiology","score":0.8252000212669373,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12025","display_name":"Hepatitis Viruses Studies and Epidemiology","score":0.8252000212669373,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11015","display_name":"Down syndrome and intellectual disability research","score":0.04470000043511391,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10340","display_name":"Hepatitis B Virus Studies","score":0.026399999856948853,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/inactivated-hepatitis-a-vaccine","display_name":"inactivated hepatitis A vaccine","score":0.8339999914169312},{"id":"https://openalex.org/keywords/down-syndrome","display_name":"Down syndrome","score":0.9789999723434448},{"id":"https://openalex.org/keywords/immunogenicity","display_name":"immunogenicity","score":0.9409999847412109},{"id":"https://openalex.org/keywords/vaccine-safety","display_name":"vaccine safety","score":0.9980000257492065},{"id":"https://openalex.org/keywords/seroconversion","display_name":"seroconversion","score":0.9259999990463257},{"id":"https://openalex.org/keywords/children","display_name":"children","score":0.6729999780654907},{"id":"https://openalex.org/keywords/injection-site-reactions","display_name":"injection site reactions","score":0.5870000123977661}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9509801864624023},{"id":"https://openalex.org/C2777451964","wikidata":"https://www.wikidata.org/wiki/Q2141450","display_name":"Seroconversion","level":3,"score":0.8979637622833252},{"id":"https://openalex.org/C2780799908","wikidata":"https://www.wikidata.org/wiki/Q3553093","display_name":"Hepatitis A vaccine","level":4,"score":0.7829421758651733},{"id":"https://openalex.org/C2780868878","wikidata":"https://www.wikidata.org/wiki/Q1660197","display_name":"Immunogenicity","level":3,"score":0.7483411431312561},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.6370726823806763},{"id":"https://openalex.org/C2775876817","wikidata":"https://www.wikidata.org/wiki/Q157661","display_name":"Hepatitis A","level":3,"score":0.5895903706550598},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.5877152681350708},{"id":"https://openalex.org/C3019983190","wikidata":"https://www.wikidata.org/wiki/Q157661","display_name":"Hepatitis a virus","level":3,"score":0.43937239050865173},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.36281707882881165},{"id":"https://openalex.org/C2776029263","wikidata":"https://www.wikidata.org/wiki/Q131742","display_name":"Hepatitis","level":2,"score":0.3555104732513428},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34573429822921753},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.2974926829338074},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.1882266104221344}],"mesh":[{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004314","descriptor_name":"Down Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D006506","descriptor_name":"Hepatitis A","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D006506","descriptor_name":"Hepatitis A","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D022362","descriptor_name":"Hepatitis A Vaccines","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D022362","descriptor_name":"Hepatitis A Vaccines","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D035922","descriptor_name":"Hepatitis A Antibodies","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1002/j.1536-4801.2004.tb00863.x","doi":"https://doi.org/10.1002/j.1536-4801.2004.tb00863.x","is_oa":true,"landing_page_url":"https://doi.org/10.1002/j.1536-4801.2004.tb00863.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.1536-4801.2004.tb00863.x","source":{"id":"https://openalex.org/S197964821","display_name":"Journal of Pediatric Gastroenterology and Nutrition","issn_l":"0277-2116","issn":["0277-2116","1536-4801"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pediatric Gastroenterology and Nutrition","raw_type":"journal-article"},{"id":"doi:10.1097/00005176-200410000-00007","doi":"https://doi.org/10.1097/00005176-200410000-00007","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00005176-200410000-00007","pdf_url":null,"source":{"id":"https://openalex.org/S197964821","display_name":"Journal of Pediatric Gastroenterology and Nutrition","issn_l":"0277-2116","issn":["0277-2116","1536-4801"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pediatric Gastroenterology and Nutrition","raw_type":"journal-article"},{"id":"pmid:15448421","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15448421","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of pediatric gastroenterology and nutrition","raw_type":"Journal Article"},{"id":"pmh:oai:www.lume.ufrgs.br:10183/245411","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10183/245411","pdf_url":null,"source":{"id":"https://openalex.org/S4306401468","display_name":"Lume (Universidade Federal do Rio Grande do Sul)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210097146","host_organization_name":"Hospital de Cl\u00ednicas de Porto Alegre","host_organization_lineage":["https://openalex.org/I4210097146"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Artigo de peri\u00f3dico"}],"best_oa_location":{"id":"doi:10.1002/j.1536-4801.2004.tb00863.x","doi":"https://doi.org/10.1002/j.1536-4801.2004.tb00863.x","is_oa":true,"landing_page_url":"https://doi.org/10.1002/j.1536-4801.2004.tb00863.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.1536-4801.2004.tb00863.x","source":{"id":"https://openalex.org/S197964821","display_name":"Journal of Pediatric Gastroenterology and Nutrition","issn_l":"0277-2116","issn":["0277-2116","1536-4801"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pediatric Gastroenterology and Nutrition","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320332162","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2014540348.pdf","grobid_xml":"https://content.openalex.org/works/W2014540348.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W1550255558","https://openalex.org/W1970654231","https://openalex.org/W1985551192","https://openalex.org/W1993809002","https://openalex.org/W1998842903","https://openalex.org/W2008214254","https://openalex.org/W2009057398","https://openalex.org/W2019402927","https://openalex.org/W2028886051","https://openalex.org/W2045734553","https://openalex.org/W2072508545","https://openalex.org/W2074915778","https://openalex.org/W2085104187","https://openalex.org/W2096154600","https://openalex.org/W2109075498","https://openalex.org/W2109971013","https://openalex.org/W2131387963","https://openalex.org/W2153054257","https://openalex.org/W2167650970","https://openalex.org/W2276907497","https://openalex.org/W2337114621","https://openalex.org/W2399412820","https://openalex.org/W2418806566","https://openalex.org/W2617506791","https://openalex.org/W4212878078","https://openalex.org/W4232037495","https://openalex.org/W4254277391"],"related_works":["https://openalex.org/W56899338","https://openalex.org/W2007034723","https://openalex.org/W1919491466","https://openalex.org/W2978856866","https://openalex.org/W2347291076","https://openalex.org/W7171928984","https://openalex.org/W2383092741","https://openalex.org/W2388122170","https://openalex.org/W203212451","https://openalex.org/W2032528638"],"abstract_inverted_index":{"OBJECTIVES:":[0],"Hepatitis":[1],"A":[2,28,77],"vaccine":[3,29,80,233],"has":[4],"not":[5,223],"been":[6],"investigated":[7],"in":[8,30,93,133,149,159,193,197,201,214,240],"children":[9,32,54,215,241],"with":[10,33,61,152,216,221,242],"Down":[11,34,62,135],"syndrome.":[12],"The":[13,204],"aim":[14],"of":[15,24,42,52,87,154,228],"this":[16],"study":[17],"was":[18,69,90,186],"to":[19,40,57,211],"evaluate":[20],"immunogenicity":[21],"and":[22,36,64,99,103,111,121,123,130,138,156,162,174,199,237],"safety":[23],"an":[25],"inactivated":[26],"hepatitis":[27,76],"noninstitutionalized":[31],"syndrome":[35,63,136],"compare":[37],"their":[38],"responses":[39],"those":[41],"healthy":[43,66,229],"control":[44,67,139,163,230],"children.":[45,231],"METHODS:":[46],"An":[47],"open,":[48],"prospective,":[49],"controlled":[50],"trial":[51],"127":[53],"ages":[55],"1":[56,110,118],"12":[58],"years,":[59],"63":[60],"64":[65],"subjects,":[68],"conducted":[70],"at":[71,97,108,116,182,219],"a":[72,94,208],"single":[73],"hospital.":[74],"Inactivated":[75],"virus":[78],"(HAV)":[79],"containing":[81],"720":[82],"enzyme-linked":[83],"immunosorbent":[84],"assay":[85],"units":[86],"alum-adsorbed":[88],"HAV":[89,212,232],"administered":[91],"intramuscularly":[92],"two-dose":[95],"schedule":[96],"0":[98],"6":[100],"months.":[101],"Seroconversion":[102,114],"anti-HAV":[104],"titers":[105,126],"were":[106,119,128,147,171],"measured":[107],"months":[109],"7.":[112],"RESULTS:":[113],"rates":[115,146],"month":[117,143],"92%":[120],"94%":[122],"geometric":[124],"mean":[125],"(GMT)":[127],"164.02":[129],"160.77":[131],"mIU/mL":[132,158],"the":[134,160,183,187],"(DS)":[137],"groups,":[140,151,164],"respectively.":[141],"At":[142],"7,":[144],"seroconversion":[145],"100%":[148],"both":[150,194],"GMT":[153,222],"1,719.86":[155],"2,344.90":[157],"DS":[161,198,217],"respectively":[165],"(P":[166],"=":[167],"0.117).":[168],"Both":[169],"doses":[170],"well":[172,235],"tolerated":[173,236],"no":[175],"significant":[176],"adverse":[177,190],"events":[178],"observed.":[179],"Local":[180],"reaction":[181],"injection":[184],"site":[185],"most":[188],"common":[189],"event":[191],"reported":[192],"groups":[195],"(15%":[196],"11%":[200],"controls).":[202],"CONCLUSIONS:":[203],"authors'":[205],"data":[206],"demonstrate":[207],"good":[209],"response":[210],"vaccination":[213],"living":[218],"home,":[220],"statistically":[224],"different":[225],"from":[226],"that":[227],"is":[234],"highly":[238],"immunogenic":[239],"DS.":[243]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}