{"id":"https://openalex.org/W2014493270","doi":"https://doi.org/10.1097/jgp.0b013e3181f52877","title":"Beyond the Dawning of the Age of Biomarkers","display_name":"Beyond the Dawning of the Age of Biomarkers","publication_year":2010,"publication_date":"2010-08-27","ids":{"openalex":"https://openalex.org/W2014493270","doi":"https://doi.org/10.1097/jgp.0b013e3181f52877","mag":"2014493270","pmid":"https://pubmed.ncbi.nlm.nih.gov/20808152"},"language":"en","primary_location":{"id":"doi:10.1097/jgp.0b013e3181f52877","doi":"https://doi.org/10.1097/jgp.0b013e3181f52877","is_oa":false,"landing_page_url":"https://doi.org/10.1097/jgp.0b013e3181f52877","pdf_url":null,"source":{"id":"https://openalex.org/S182891740","display_name":"American Journal of Geriatric Psychiatry","issn_l":"1064-7481","issn":["1064-7481","1545-7214"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Geriatric Psychiatry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006645872","display_name":"Deborah Blacker","orcid":"https://orcid.org/0000-0001-6107-7376","observed_orcids":["https://orcid.org/0000-0001-6107-7376"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Deborah Blacker","raw_affiliation_strings":["Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School; and Department of Epidemiology, Harvard School of Public Health, Boston, MA","Department of Epidemiology, Harvard School of Public Health, Boston, MA","Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School; and Department of Epidemiology, Harvard School of Public Health, Boston, MA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Department of Epidemiology, Harvard School of Public Health, Boston, MA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5006645872"],"corresponding_institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"],"apc_list":{"value":4400,"currency":"USD","value_usd":4400},"apc_paid":null,"fwci":0.2086,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.5894542,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"18","issue":"11","first_page":"955","last_page":"958"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.5961999893188477,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.5961999893188477,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12848","display_name":"Psychological Testing and Assessment","score":0.12630000710487366,"subfield":{"id":"https://openalex.org/subfields/3202","display_name":"Applied Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T14393","display_name":"Health, Environment, Cognitive Aging","score":0.06400000303983688,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.9919999837875366},{"id":"https://openalex.org/keywords/geriatric-psychiatry","display_name":"geriatric psychiatry","score":0.8460000157356262},{"id":"https://openalex.org/keywords/dementia","display_name":"dementia","score":0.3880000114440918},{"id":"https://openalex.org/keywords/early-diagnosis","display_name":"early diagnosis","score":0.5339999794960022},{"id":"https://openalex.org/keywords/disease-progression-monitoring","display_name":"disease progression monitoring","score":0.7620000243186951}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7169359922409058},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.7143625020980835},{"id":"https://openalex.org/C141341695","wikidata":"https://www.wikidata.org/wiki/Q2368661","display_name":"Surrogate endpoint","level":2,"score":0.641157329082489},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.595963180065155},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5043374300003052},{"id":"https://openalex.org/C163763905","wikidata":"https://www.wikidata.org/wiki/Q17075943","display_name":"Precision medicine","level":2,"score":0.4726898968219757},{"id":"https://openalex.org/C124535831","wikidata":"https://www.wikidata.org/wiki/Q4915074","display_name":"Biomarker discovery","level":4,"score":0.4450923204421997},{"id":"https://openalex.org/C203092338","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Clinical endpoint","level":3,"score":0.42241528630256653},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.37466737627983093},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.33471983671188354},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2496967911720276},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1097/jgp.0b013e3181f52877","doi":"https://doi.org/10.1097/jgp.0b013e3181f52877","is_oa":false,"landing_page_url":"https://doi.org/10.1097/jgp.0b013e3181f52877","pdf_url":null,"source":{"id":"https://openalex.org/S182891740","display_name":"American Journal of Geriatric Psychiatry","issn_l":"1064-7481","issn":["1064-7481","1545-7214"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Geriatric Psychiatry","raw_type":"journal-article"},{"id":"pmid:20808152","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20808152","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry","raw_type":"Editorial"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9074000120162964,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1544338382","https://openalex.org/W1978245886","https://openalex.org/W1979755700","https://openalex.org/W1989294424","https://openalex.org/W2017079501","https://openalex.org/W2027484604","https://openalex.org/W2028156861","https://openalex.org/W2031233001","https://openalex.org/W2031489026","https://openalex.org/W2035466596","https://openalex.org/W2038463965","https://openalex.org/W2043422348","https://openalex.org/W2045454808","https://openalex.org/W2106481760","https://openalex.org/W2106931873","https://openalex.org/W2107199945","https://openalex.org/W2131830246","https://openalex.org/W2133719476","https://openalex.org/W2135771073","https://openalex.org/W2135816796","https://openalex.org/W2140425743","https://openalex.org/W2156220037","https://openalex.org/W2167720733","https://openalex.org/W2511246053"],"related_works":["https://openalex.org/W2312500241","https://openalex.org/W7044192652","https://openalex.org/W6899536297","https://openalex.org/W2025405552","https://openalex.org/W1550183959","https://openalex.org/W2411177682","https://openalex.org/W7095876966","https://openalex.org/W2102056787","https://openalex.org/W4234178349","https://openalex.org/W4396784318"],"abstract_inverted_index":null,"counts_by_year":[{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}