{"id":"https://openalex.org/W2014390331","doi":"https://doi.org/10.1016/j.jacc.2006.12.036","title":"Randomized Early Versus Late Abciximab in Acute Myocardial Infarction Treated With Primary Coronary Intervention (RELAx-AMI Trial)","display_name":"Randomized Early Versus Late Abciximab in Acute Myocardial Infarction Treated With Primary Coronary Intervention (RELAx-AMI Trial)","publication_year":2007,"publication_date":"2007-03-27","ids":{"openalex":"https://openalex.org/W2014390331","doi":"https://doi.org/10.1016/j.jacc.2006.12.036","mag":"2014390331","pmid":"https://pubmed.ncbi.nlm.nih.gov/17418289"},"language":"en","primary_location":{"id":"doi:10.1016/j.jacc.2006.12.036","doi":"https://doi.org/10.1016/j.jacc.2006.12.036","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jacc.2006.12.036","pdf_url":"https://www.sciencedirect.com/science/article/pii/S073510970700335X/pdf","source":{"id":"https://openalex.org/S60865174","display_name":"Journal of the American College of Cardiology","issn_l":"0735-1097","issn":["0735-1097","1558-3597"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.sciencedirect.com/science/article/pii/S073510970700335X/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037728621","display_name":"Mauro Maioli","orcid":"https://orcid.org/0000-0001-8856-9813","observed_orcids":["https://orcid.org/0000-0001-8856-9813"]},"institutions":[{"id":"https://openalex.org/I4210111090","display_name":"Ospedale Misericordia e Dolce","ror":"https://ror.org/01zh1d121","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210111090"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Mauro Maioli","raw_affiliation_strings":["Division of Cardiology, Misericordia e Dolce Hospital, Prato, Italy. mauromaioli@tiscali.it","Division of Cardiology, Misericordia e Dolce Hospital, Prato, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Misericordia e Dolce Hospital, Prato, Italy. mauromaioli@tiscali.it","institution_ids":["https://openalex.org/I4210111090"]},{"raw_affiliation_string":"Division of Cardiology, Misericordia e Dolce Hospital, Prato, Italy","institution_ids":["https://openalex.org/I4210111090"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075302859","display_name":"Francesco Bellandi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210111090","display_name":"Ospedale Misericordia e Dolce","ror":"https://ror.org/01zh1d121","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210111090"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Francesco Bellandi","raw_affiliation_strings":["Division of Cardiology, Misericordia e Dolce Hospital, Prato, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Misericordia e Dolce Hospital, Prato, Italy","institution_ids":["https://openalex.org/I4210111090"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074608390","display_name":"Mario Leoncini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210111090","display_name":"Ospedale Misericordia e Dolce","ror":"https://ror.org/01zh1d121","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210111090"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Mario Leoncini","raw_affiliation_strings":["Division of Cardiology, Misericordia e Dolce Hospital, Prato, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Misericordia e Dolce Hospital, Prato, Italy","institution_ids":["https://openalex.org/I4210111090"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076817668","display_name":"Anna Toso","orcid":"https://orcid.org/0000-0002-8404-3993","observed_orcids":["https://orcid.org/0000-0002-8404-3993"]},"institutions":[{"id":"https://openalex.org/I4210111090","display_name":"Ospedale Misericordia e Dolce","ror":"https://ror.org/01zh1d121","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210111090"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Anna Toso","raw_affiliation_strings":["Division of Cardiology, Misericordia e Dolce Hospital, Prato, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Misericordia e Dolce Hospital, Prato, Italy","institution_ids":["https://openalex.org/I4210111090"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113930624","display_name":"Roberto Piero Dabizzi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210111090","display_name":"Ospedale Misericordia e Dolce","ror":"https://ror.org/01zh1d121","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210111090"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Roberto Piero Dabizzi","raw_affiliation_strings":["Division of Cardiology, Misericordia e Dolce Hospital, Prato, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Misericordia e Dolce Hospital, Prato, Italy","institution_ids":["https://openalex.org/I4210111090"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5037728621"],"corresponding_institution_ids":["https://openalex.org/I4210111090"],"apc_list":{"value":7166,"currency":"USD","value_usd":7166},"apc_paid":null,"fwci":11.3819,"has_fulltext":true,"cited_by_count":117,"citation_normalized_percentile":{"value":0.98872473,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"49","issue":"14","first_page":"1517","last_page":"1524"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.836899995803833,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.836899995803833,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11064","display_name":"Antiplatelet Therapy and Cardiovascular Diseases","score":0.13979999721050262,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.010700000450015068,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/abciximab","display_name":"abciximab","score":0.9810000061988831},{"id":"https://openalex.org/keywords/acute-myocardial-infarction","display_name":"acute myocardial infarction","score":0.9700000286102295},{"id":"https://openalex.org/keywords/primary-percutaneous-coronary-intervention","display_name":"primary percutaneous coronary intervention","score":0.9819999933242798},{"id":"https://openalex.org/keywords/glycoprotein-iib-iiia-inhibitors","display_name":"glycoprotein IIb/IIIa inhibitors","score":0.984000027179718},{"id":"https://openalex.org/keywords/timing-of-drug-administration","display_name":"timing of drug administration","score":0.6809999942779541},{"id":"https://openalex.org/keywords/timi-flow-grade","display_name":"TIMI flow","score":0.7250000238418579},{"id":"https://openalex.org/keywords/myocardial-blush-grade","display_name":"myocardial blush grade","score":0.8399999737739563},{"id":"https://openalex.org/keywords/tissue-perfusion","display_name":"tissue perfusion","score":0.7760000228881836},{"id":"https://openalex.org/keywords/left-ventricular-recovery","display_name":"left ventricular function recovery","score":0.9179999828338623},{"id":"https://openalex.org/keywords/ejection-fraction","display_name":"ejection fraction","score":0.7910000085830688},{"id":"https://openalex.org/keywords/wall-motion-score-index","display_name":"wall motion score index","score":0.9470000267028809},{"id":"https://openalex.org/keywords/reperfusion-therapy","display_name":"reperfusion therapy","score":0.5580000281333923}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9540752172470093},{"id":"https://openalex.org/C2777995511","wikidata":"https://www.wikidata.org/wiki/Q2897649","display_name":"TIMI","level":4,"score":0.94171142578125},{"id":"https://openalex.org/C2777871224","wikidata":"https://www.wikidata.org/wiki/Q307088","display_name":"Abciximab","level":4,"score":0.9073507189750671},{"id":"https://openalex.org/C45393284","wikidata":"https://www.wikidata.org/wiki/Q191012","display_name":"Conventional PCI","level":3,"score":0.8605338335037231},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.7976396679878235},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.7777881622314453},{"id":"https://openalex.org/C2780400711","wikidata":"https://www.wikidata.org/wiki/Q2008344","display_name":"Percutaneous coronary intervention","level":3,"score":0.7710466384887695},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.731311559677124},{"id":"https://openalex.org/C2779581417","wikidata":"https://www.wikidata.org/wiki/Q1931577","display_name":"Thrombolysis","level":3,"score":0.623125433921814},{"id":"https://openalex.org/C78085059","wikidata":"https://www.wikidata.org/wiki/Q641303","display_name":"Ejection fraction","level":3,"score":0.6173335313796997},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.4462437331676483},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.14288294315338135}],"mesh":[{"descriptor_ui":"D000077284","descriptor_name":"Abciximab","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D004638","descriptor_name":"Emergency Treatment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007140","descriptor_name":"Immunoglobulin Fab Fragments","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015906","descriptor_name":"Angioplasty, Balloon, Coronary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016277","descriptor_name":"Ventricular Function, Left","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017023","descriptor_name":"Coronary Angiography","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D019039","descriptor_name":"Platelet Glycoprotein GPIIb-IIIa Complex","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.jacc.2006.12.036","doi":"https://doi.org/10.1016/j.jacc.2006.12.036","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jacc.2006.12.036","pdf_url":"https://www.sciencedirect.com/science/article/pii/S073510970700335X/pdf","source":{"id":"https://openalex.org/S60865174","display_name":"Journal of the American College of Cardiology","issn_l":"0735-1097","issn":["0735-1097","1558-3597"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"journal-article"},{"id":"pmid:17418289","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17418289","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"Comparative Study"},{"id":"pmh:oai:zenodo.org:207752","doi":null,"is_oa":true,"landing_page_url":"https://www.openaccessrepository.it/record/207752","pdf_url":null,"source":{"id":"https://openalex.org/S4306402478","display_name":"INFM-OAR (INFN Catania)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210116497","host_organization_name":"Istituto Nazionale di Fisica Nucleare, Sezione di Catania","host_organization_lineage":["https://openalex.org/I4210116497"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"doi:10.5281/zenodo.207752","doi":"https://doi.org/10.5281/zenodo.207752","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.207752","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Image"}],"best_oa_location":{"id":"doi:10.1016/j.jacc.2006.12.036","doi":"https://doi.org/10.1016/j.jacc.2006.12.036","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jacc.2006.12.036","pdf_url":"https://www.sciencedirect.com/science/article/pii/S073510970700335X/pdf","source":{"id":"https://openalex.org/S60865174","display_name":"Journal of the American College of Cardiology","issn_l":"0735-1097","issn":["0735-1097","1558-3597"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2014390331.pdf","grobid_xml":"https://content.openalex.org/works/W2014390331.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W183456607","https://openalex.org/W1935192134","https://openalex.org/W1972109636","https://openalex.org/W1988415842","https://openalex.org/W1997521359","https://openalex.org/W1997927344","https://openalex.org/W1998140089","https://openalex.org/W2000210172","https://openalex.org/W2008845088","https://openalex.org/W2025410012","https://openalex.org/W2029038656","https://openalex.org/W2035015235","https://openalex.org/W2035790329","https://openalex.org/W2037244319","https://openalex.org/W2037709494","https://openalex.org/W2042759990","https://openalex.org/W2068153038","https://openalex.org/W2075585405","https://openalex.org/W2085413583","https://openalex.org/W2090744742","https://openalex.org/W2091054752","https://openalex.org/W2091364881","https://openalex.org/W2091511638","https://openalex.org/W2110108283","https://openalex.org/W2111255663","https://openalex.org/W2124788115","https://openalex.org/W2134741080","https://openalex.org/W2135217811","https://openalex.org/W2144212359","https://openalex.org/W2144896577","https://openalex.org/W2151504897","https://openalex.org/W2153871853","https://openalex.org/W2333133657","https://openalex.org/W2523584376","https://openalex.org/W2568050971","https://openalex.org/W2990123797","https://openalex.org/W4231815458"],"related_works":["https://openalex.org/W2153871853","https://openalex.org/W2112925618","https://openalex.org/W2079060367","https://openalex.org/W2150146339","https://openalex.org/W2027495427","https://openalex.org/W183456607","https://openalex.org/W2109446643","https://openalex.org/W1985331380","https://openalex.org/W1607207181","https://openalex.org/W2120828479"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":15}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}