{"id":"https://openalex.org/W2014388162","doi":"https://doi.org/10.1097/pcc.0b013e3181849e62","title":"Susceptibility to meningococcal infection\u2014Nature versus nurture?*","display_name":"Susceptibility to meningococcal infection\u2014Nature versus nurture?*","publication_year":2008,"publication_date":"2008-09-01","ids":{"openalex":"https://openalex.org/W2014388162","doi":"https://doi.org/10.1097/pcc.0b013e3181849e62","mag":"2014388162","pmid":"https://pubmed.ncbi.nlm.nih.gov/18779704"},"language":"en","primary_location":{"id":"doi:10.1097/pcc.0b013e3181849e62","doi":"https://doi.org/10.1097/pcc.0b013e3181849e62","is_oa":false,"landing_page_url":"https://doi.org/10.1097/pcc.0b013e3181849e62","pdf_url":null,"source":{"id":"https://openalex.org/S180821644","display_name":"Pediatric Critical Care Medicine","issn_l":"1529-7535","issn":["1529-7535","1947-3893"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Critical Care Medicine","raw_type":"journal-article"},"volume":null,"type":"editorial","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022990670","display_name":"Ajit Sarnaik","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ajit A. Sarnaik","raw_affiliation_strings":["Departments of Critical Care Medicine and Pediatrics, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, PA (Clark)","Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, PA (Sarnaik)","University of Pittsburgh School of Nursing, Pittsburgh, PA (Conley)","The authors have not disclosed any potential conflicts of interest"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Critical Care Medicine and Pediatrics, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, PA (Clark)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, PA (Sarnaik)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"University of Pittsburgh School of Nursing, Pittsburgh, PA (Conley)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"The authors have not disclosed any potential conflicts of interest","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016803157","display_name":"Yvette P. Conley","orcid":"https://orcid.org/0000-0002-1784-6067","observed_orcids":["https://orcid.org/0000-0002-1784-6067"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yvette P. Conley","raw_affiliation_strings":["Departments of Critical Care Medicine and Pediatrics, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, PA (Clark)","Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, PA (Sarnaik)","University of Pittsburgh School of Nursing, Pittsburgh, PA (Conley)","The authors have not disclosed any potential conflicts of interest"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Critical Care Medicine and Pediatrics, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, PA (Clark)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, PA (Sarnaik)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"University of Pittsburgh School of Nursing, Pittsburgh, PA (Conley)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"The authors have not disclosed any potential conflicts of interest","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058521832","display_name":"Robert S. B. Clark","orcid":"https://orcid.org/0000-0002-0806-8005","observed_orcids":["https://orcid.org/0000-0002-0806-8005"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert S. B. Clark","raw_affiliation_strings":["Departments of Critical Care Medicine and Pediatrics, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, PA (Clark)","Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, PA (Sarnaik)","University of Pittsburgh School of Nursing, Pittsburgh, PA (Conley)","The authors have not disclosed any potential conflicts of interest"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Critical Care Medicine and Pediatrics, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, PA (Clark)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, PA (Sarnaik)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"University of Pittsburgh School of Nursing, Pittsburgh, PA (Conley)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"The authors have not disclosed any potential conflicts of interest","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I170201317"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"9","issue":"5","first_page":"540","last_page":"542"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/meningococcal-disease","display_name":"meningococcal disease","score":0.9940000176429749},{"id":"https://openalex.org/keywords/infection-susceptibility","display_name":"infection susceptibility","score":0.7929999828338623},{"id":"https://openalex.org/keywords/genetic-factors","display_name":"genetic factors","score":0.5230000019073486},{"id":"https://openalex.org/keywords/environmental-factors","display_name":"environmental factors","score":0.9160000085830688},{"id":"https://openalex.org/keywords/host-susceptibility","display_name":"host susceptibility","score":0.36500000953674316}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7628235816955566},{"id":"https://openalex.org/C2779463800","wikidata":"https://www.wikidata.org/wiki/Q5062222","display_name":"Center (category theory)","level":2,"score":0.5754212141036987},{"id":"https://openalex.org/C2993838110","wikidata":"https://www.wikidata.org/wiki/Q494230","display_name":"Medical school","level":2,"score":0.5011193752288818},{"id":"https://openalex.org/C120452360","wikidata":"https://www.wikidata.org/wiki/Q1773859","display_name":"Nature versus nurture","level":2,"score":0.41468170285224915},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.38478347659111023},{"id":"https://openalex.org/C509550671","wikidata":"https://www.wikidata.org/wiki/Q126945","display_name":"Medical education","level":1,"score":0.2262422740459442},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.05534636974334717},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.0},{"id":"https://openalex.org/C19165224","wikidata":"https://www.wikidata.org/wiki/Q23404","display_name":"Anthropology","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000099291","descriptor_name":"Adducins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002148","descriptor_name":"Calmodulin-Binding Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007703","descriptor_name":"Peptidyl-Dipeptidase A","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008589","descriptor_name":"Meningococcal Infections","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011110","descriptor_name":"Polymorphism, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011941","descriptor_name":"Receptors, Adrenergic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013534","descriptor_name":"Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015278","descriptor_name":"Intensive Care Units, Pediatric","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1097/pcc.0b013e3181849e62","doi":"https://doi.org/10.1097/pcc.0b013e3181849e62","is_oa":false,"landing_page_url":"https://doi.org/10.1097/pcc.0b013e3181849e62","pdf_url":null,"source":{"id":"https://openalex.org/S180821644","display_name":"Pediatric Critical Care Medicine","issn_l":"1529-7535","issn":["1529-7535","1947-3893"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Critical Care Medicine","raw_type":"journal-article"},{"id":"pmid:18779704","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18779704","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies","raw_type":"Comment"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.5699999928474426,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W122163712","https://openalex.org/W174362136","https://openalex.org/W1971097161","https://openalex.org/W2011798264","https://openalex.org/W2019856948","https://openalex.org/W2021978469","https://openalex.org/W2024066660","https://openalex.org/W2046838656","https://openalex.org/W2048837363","https://openalex.org/W2063128977","https://openalex.org/W2084445398","https://openalex.org/W2088139075","https://openalex.org/W2089151545","https://openalex.org/W2097328750","https://openalex.org/W2107513722","https://openalex.org/W2121283148","https://openalex.org/W2133700480","https://openalex.org/W2156209052"],"related_works":["https://openalex.org/W2409956961","https://openalex.org/W2037424438","https://openalex.org/W2067393716","https://openalex.org/W7048898612","https://openalex.org/W1487888540","https://openalex.org/W4246096637","https://openalex.org/W2010383590","https://openalex.org/W6887877076","https://openalex.org/W1987421906","https://openalex.org/W2070686328"],"abstract_inverted_index":{"Safar":[0,30],"Center":[1,31],"for":[2,32],"Resuscitation":[3,33],"Research,":[4,34],"University":[5,14,35],"of":[6,9,15,18,24,36,39,52],"Pittsburgh":[7,16,37],"School":[8,17,38],"Medicine,":[10,40],"Pittsburgh,":[11,20,41],"PA":[12,21,42],"(Sarnaik)":[13],"Nursing,":[19],"(Conley)":[22],"Departments":[23],"Critical":[25],"Care":[26],"Medicine":[27],"and":[28],"Pediatrics,":[29],"(Clark)":[43],"The":[44],"authors":[45],"have":[46],"not":[47],"disclosed":[48],"any":[49],"potential":[50],"conflicts":[51],"interest.":[53]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}