{"id":"https://openalex.org/W2014290287","doi":"https://doi.org/10.1042/bj20140795","title":"A novel method for non-transferrin-bound iron quantification by chelatable fluorescent beads based on flow cytometry","display_name":"A novel method for non-transferrin-bound iron quantification by chelatable fluorescent beads based on flow cytometry","publication_year":2014,"publication_date":"2014-08-06","ids":{"openalex":"https://openalex.org/W2014290287","doi":"https://doi.org/10.1042/bj20140795","mag":"2014290287","pmid":"https://pubmed.ncbi.nlm.nih.gov/25093426"},"language":"en","primary_location":{"id":"doi:10.1042/bj20140795","doi":"https://doi.org/10.1042/bj20140795","is_oa":false,"landing_page_url":"https://doi.org/10.1042/bj20140795","pdf_url":null,"source":{"id":"https://openalex.org/S44425019","display_name":"Biochemical Journal","issn_l":"0264-6021","issn":["0264-6021","1470-8728"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001022230","display_name":"Yongmin Ma","orcid":"https://orcid.org/0000-0002-9521-767X","observed_orcids":["https://orcid.org/0000-0002-9521-767X"]},"institutions":[{"id":"https://openalex.org/I114539943","display_name":"Zhejiang Chinese Medical University","ror":"https://ror.org/04epb4p87","country_code":"CN","type":"education","lineage":["https://openalex.org/I114539943"]},{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["CN","GB"],"is_corresponding":false,"raw_author_name":"Yongmin Ma","raw_affiliation_strings":["King's College London, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, U.K","Zhejiang Chinese Medical University, 548 Binwen Road, Hangzhou 310053, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"King's College London, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, U.K","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Zhejiang Chinese Medical University, 548 Binwen Road, Hangzhou 310053, P.R. China","institution_ids":["https://openalex.org/I114539943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043468095","display_name":"Maria Podinovskaia","orcid":"https://orcid.org/0000-0003-1351-6340","observed_orcids":["https://orcid.org/0000-0003-1351-6340"]},"institutions":[{"id":"https://openalex.org/I4210089966","display_name":"London School of Hygiene & Tropical Medicine","ror":"https://ror.org/00a0jsq62","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210089966"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Maria Podinovskaia","raw_affiliation_strings":["London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, U.K","institution_ids":["https://openalex.org/I4210089966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020535984","display_name":"Patricia Evans","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Patricia J. Evans","raw_affiliation_strings":["Department of Haematology, University College London, London WC1E 6BT, U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University College London, London WC1E 6BT, U.K","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064926748","display_name":"Giovanni Emma","orcid":"https://orcid.org/0000-0002-4791-2205","observed_orcids":["https://orcid.org/0000-0002-4791-2205"]},"institutions":[{"id":"https://openalex.org/I25217355","display_name":"University of Pavia","ror":"https://ror.org/00s6t1f81","country_code":"IT","type":"education","lineage":["https://openalex.org/I25217355"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giovanni Emma","raw_affiliation_strings":["Department of Chemistry, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy","institution_ids":["https://openalex.org/I25217355"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108084999","display_name":"Ulrich E. Schaible","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210089966","display_name":"London School of Hygiene & Tropical Medicine","ror":"https://ror.org/00a0jsq62","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210089966"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ulrich\u00a0E. Schaible","raw_affiliation_strings":["London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, U.K","institution_ids":["https://openalex.org/I4210089966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049244658","display_name":"John B. Porter","orcid":"https://orcid.org/0000-0003-3000-9359","observed_orcids":["https://orcid.org/0000-0003-3000-9359"]},"institutions":[{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"John Porter","raw_affiliation_strings":["Department of Haematology, University College London, London WC1E 6BT, U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, University College London, London WC1E 6BT, U.K","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020843793","display_name":"Robert C. Hider","orcid":"https://orcid.org/0000-0003-1330-5797","observed_orcids":["https://orcid.org/0000-0003-1330-5797"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Robert\u00a0C. Hider","raw_affiliation_strings":["King's College London, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"King's College London, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, U.K","institution_ids":["https://openalex.org/I183935753"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.6705,"has_fulltext":false,"cited_by_count":30,"citation_normalized_percentile":{"value":0.906234,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"463","issue":"3","first_page":"351","last_page":"362"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.9545999765396118,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.9545999765396118,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10532","display_name":"Molecular Sensors and Ion Detection","score":0.031599998474121094,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10180","display_name":"Analytical chemistry methods development","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/non-transferrin-bound-iron","display_name":"non-transferrin-bound iron","score":1.0},{"id":"https://openalex.org/keywords/fluorescent-microspheres","display_name":"fluorescent microspheres","score":0.8709999918937683},{"id":"https://openalex.org/keywords/chelating-agents","display_name":"chelating agents","score":0.734000027179718},{"id":"https://openalex.org/keywords/hydroxypyridinone","display_name":"hydroxypyridinone","score":0.9279999732971191},{"id":"https://openalex.org/keywords/flow-cytometry","display_name":"flow cytometry","score":0.6809999942779541},{"id":"https://openalex.org/keywords/transferrin","display_name":"transferrin","score":0.7730000019073486},{"id":"https://openalex.org/keywords/ferritin","display_name":"ferritin","score":0.9110000133514404}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.792669951915741},{"id":"https://openalex.org/C22814914","wikidata":"https://www.wikidata.org/wiki/Q410473","display_name":"Transferrin","level":2,"score":0.7880000472068787},{"id":"https://openalex.org/C179687394","wikidata":"https://www.wikidata.org/wiki/Q4826281","display_name":"Autofluorescence","level":3,"score":0.760170578956604},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.6834787130355835},{"id":"https://openalex.org/C197404232","wikidata":"https://www.wikidata.org/wiki/Q319827","display_name":"Chelation","level":2,"score":0.6578812599182129},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.6274789571762085},{"id":"https://openalex.org/C2778319317","wikidata":"https://www.wikidata.org/wiki/Q22327449","display_name":"Ferritin","level":2,"score":0.5959900617599487},{"id":"https://openalex.org/C178516000","wikidata":"https://www.wikidata.org/wiki/Q3023362","display_name":"Denticity","level":3,"score":0.5170539021492004},{"id":"https://openalex.org/C32264632","wikidata":"https://www.wikidata.org/wiki/Q1134983","display_name":"Transferrin receptor","level":3,"score":0.44134756922721863},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.41668838262557983},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3811075687408447},{"id":"https://openalex.org/C544153396","wikidata":"https://www.wikidata.org/wiki/Q11426","display_name":"Metal","level":2,"score":0.18223685026168823},{"id":"https://openalex.org/C179104552","wikidata":"https://www.wikidata.org/wiki/Q11165","display_name":"Inorganic chemistry","level":1,"score":0.13752520084381104},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.11585924029350281},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.10820576548576355},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07707497477531433},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D005293","descriptor_name":"Ferritins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D005293","descriptor_name":"Ferritins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D005434","descriptor_name":"Flow Cytometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007501","descriptor_name":"Iron","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D007502","descriptor_name":"Iron Chelating Agents","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D007502","descriptor_name":"Iron Chelating Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011714","descriptor_name":"Pyrans","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D011714","descriptor_name":"Pyrans","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011728","descriptor_name":"Pyridones","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D011728","descriptor_name":"Pyridones","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012709","descriptor_name":"Serum Albumin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012709","descriptor_name":"Serum Albumin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014168","descriptor_name":"Transferrin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014168","descriptor_name":"Transferrin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D019190","descriptor_name":"Iron Overload","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1042/bj20140795","doi":"https://doi.org/10.1042/bj20140795","is_oa":false,"landing_page_url":"https://doi.org/10.1042/bj20140795","pdf_url":null,"source":{"id":"https://openalex.org/S44425019","display_name":"Biochemical Journal","issn_l":"0264-6021","issn":["0264-6021","1470-8728"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Journal","raw_type":"journal-article"},{"id":"pmid:25093426","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25093426","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Biochemical journal","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1466109","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/1466109/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BIOCHEMICAL JOURNAL , 463 pp. 351-362. (2014)","raw_type":"Article"},{"id":"pmh:oai:researchonline.lshtm.ac.uk:2006386","doi":null,"is_oa":false,"landing_page_url":"https://researchonline.lshtm.ac.uk/id/eprint/2006386/","pdf_url":null,"source":{"id":"https://openalex.org/S4306402527","display_name":"LSHTM Research Online (London School of Hygiene and Tropical Medicine)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210089966","host_organization_name":"London School of Hygiene & Tropical Medicine","host_organization_lineage":["https://openalex.org/I4210089966"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6240000128746033,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5498960014","display_name":"Novel approaches to quantitation and speciation of plasma non-transferrin bound iron: implications for prevention of iron mediated toxicity.","funder_award_id":"093209/Z/10/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W7882087","https://openalex.org/W158899810","https://openalex.org/W170005218","https://openalex.org/W1595702568","https://openalex.org/W1968719874","https://openalex.org/W1976659843","https://openalex.org/W1983523884","https://openalex.org/W1984780486","https://openalex.org/W1987073945","https://openalex.org/W1988872182","https://openalex.org/W1996345791","https://openalex.org/W2001408672","https://openalex.org/W2002944575","https://openalex.org/W2006122975","https://openalex.org/W2006250045","https://openalex.org/W2013363580","https://openalex.org/W2013435298","https://openalex.org/W2014884073","https://openalex.org/W2019742598","https://openalex.org/W2027853843","https://openalex.org/W2030417744","https://openalex.org/W2031743034","https://openalex.org/W2033066083","https://openalex.org/W2033392675","https://openalex.org/W2033987449","https://openalex.org/W2035051218","https://openalex.org/W2038996441","https://openalex.org/W2039133702","https://openalex.org/W2040072456","https://openalex.org/W2042261978","https://openalex.org/W2050577184","https://openalex.org/W2054308752","https://openalex.org/W2056149198","https://openalex.org/W2056537429","https://openalex.org/W2072738759","https://openalex.org/W2078904403","https://openalex.org/W2084852533","https://openalex.org/W2085871472","https://openalex.org/W2090219574","https://openalex.org/W2097831477","https://openalex.org/W2099727192","https://openalex.org/W2117280779","https://openalex.org/W2129422969","https://openalex.org/W2165551729","https://openalex.org/W2235163258","https://openalex.org/W3148765499","https://openalex.org/W3187992181","https://openalex.org/W6658744788"],"related_works":["https://openalex.org/W1995396863","https://openalex.org/W2419101479","https://openalex.org/W2001408672","https://openalex.org/W7882087","https://openalex.org/W1519933919","https://openalex.org/W1976659843","https://openalex.org/W2277018705","https://openalex.org/W1968719874","https://openalex.org/W4319868804","https://openalex.org/W4400804176"],"abstract_inverted_index":{"The":[0,96,169,181],"reliable":[1],"measurement":[2,71],"of":[3,98,135,138,148,162,171],"non-transferrin-bound":[4],"iron":[5,55,122,144,149],"(NTBI)":[6],"in":[7,174],"serum":[8,52,83],"has":[9,102],"proved":[10],"to":[11,45,59,76,178],"be":[12,65],"difficult":[13],"and":[14,23,35,61,67,82,90,116,142,152,164],"generally":[15],"time":[16],"consuming.":[17],"We":[18,30],"have":[19,93,183],"sought":[20],"a":[21,28,32,37,41],"simple":[22],"fast":[24],"method":[25],"for":[26],"such":[27],"determination.":[29],"adopted":[31],"fluorescence":[33],"assay":[34],"designed":[36],"fluorescent":[38,89],"dye":[39],"with":[40,120,159,186],"chelating":[42,91,100],"agent":[43],"attached":[44],"sense":[46],"iron.":[47],"To":[48],"avoid":[49],"autofluorescence":[50,63],"from":[51,69,150,156,189],"samples,":[53],"the":[54,62,70,77,99,129,175,190],"probes":[56],"were":[57,167],"linked":[58],"beads":[60,81,86,132],"could":[64],"separated":[66],"excluded":[68],"by":[72],"flow":[73],"cytometry":[74],"due":[75],"size":[78],"difference":[79],"between":[80],"proteins.":[84],"Fluorescent":[85],"containing":[87],"both":[88],"moieties":[92],"been":[94,103,184],"synthesized.":[95],"nature":[97],"function":[101],"systematically":[104],"investigated":[105],"using":[106],"four":[107],"different":[108,121,160],"chelators:":[109],"bidentate":[110,112],"hydroxypyranone,":[111],"hydroxypyridinone,":[113,118],"hexadentate":[114,117,130],"hydroxypyranone":[115],"each":[119],"affinity":[123],"constants.":[124],"Competition":[125],"studies":[126],"demonstrate":[127],"that":[128],"hydroxypyridinone-based":[131],"are":[133],"capable":[134],"scavenging":[136],"most":[137],"low":[139],"molecular":[140],"mass":[141],"albumin-bound":[143],"but":[145],"negligible":[146],"amounts":[147],"transferrin":[151],"ferritin.":[153],"Serum":[154],"samples":[155],"30":[157],"patients":[158],"types":[161],"disease":[163],"normal":[165],"volunteers":[166],"measured.":[168],"concentrations":[170],"NTBI":[172],"fall":[173],"range":[176],"-0.41":[177],"+6.5":[179],"\u03bcM.":[180],"data":[182],"compared":[185],"those":[187],"obtained":[188],"traditional":[191],"'NTA'":[192],"method.":[193]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}