{"id":"https://openalex.org/W2014215331","doi":"https://doi.org/10.1677/joe.0.1120431","title":"Response of adrenal cells to parathyroid hormone stimulation","display_name":"Response of adrenal cells to parathyroid hormone stimulation","publication_year":1987,"publication_date":"1987-03-01","ids":{"openalex":"https://openalex.org/W2014215331","doi":"https://doi.org/10.1677/joe.0.1120431","mag":"2014215331","pmid":"https://pubmed.ncbi.nlm.nih.gov/3031192"},"language":"en","primary_location":{"id":"doi:10.1677/joe.0.1120431","doi":"https://doi.org/10.1677/joe.0.1120431","is_oa":false,"landing_page_url":"https://doi.org/10.1677/joe.0.1120431","pdf_url":null,"source":{"id":"https://openalex.org/S34842069","display_name":"Journal of Endocrinology","issn_l":"0022-0795","issn":["0022-0795","1479-6805"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319937","host_organization_name":"Bioscientifica","host_organization_lineage":["https://openalex.org/P4310319937"],"host_organization_lineage_names":["Bioscientifica"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Endocrinology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029777782","display_name":"Jacob Rosenberg","orcid":"https://orcid.org/0000-0002-0063-1086","observed_orcids":["https://orcid.org/0000-0002-0063-1086"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Rosenberg","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038188861","display_name":"Mark Pines","orcid":"https://orcid.org/0000-0002-8981-2843","observed_orcids":["https://orcid.org/0000-0002-8981-2843"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Pines","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5086708190","display_name":"Shmuel Hurwitz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. Hurwitz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.9977,"has_fulltext":false,"cited_by_count":52,"citation_normalized_percentile":{"value":0.8515625,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"112","issue":"3","first_page":"431","last_page":"437"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.7567999958992004,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.7567999958992004,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11839","display_name":"Hormonal Regulation and Hypertension","score":0.07750000059604645,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.051600001752376556,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/parathyroid-hormone","display_name":"parathyroid hormone","score":0.9990000128746033},{"id":"https://openalex.org/keywords/adrenal-cells","display_name":"adrenal cells","score":0.8309999704360962},{"id":"https://openalex.org/keywords/adrenocortical-cells","display_name":"adrenocortical cells","score":0.8659999966621399},{"id":"https://openalex.org/keywords/camp","display_name":"cyclic AMP","score":0.8849999904632568},{"id":"https://openalex.org/keywords/aldosterone-secretion","display_name":"aldosterone secretion","score":0.9039999842643738},{"id":"https://openalex.org/keywords/corticosterone-secretion","display_name":"corticosterone secretion","score":0.9589999914169312},{"id":"https://openalex.org/keywords/acth","display_name":"ACTH","score":0.9440000057220459},{"id":"https://openalex.org/keywords/parathyroid-hormone-receptor","display_name":"parathyroid hormone receptor","score":0.7429999709129333},{"id":"https://openalex.org/keywords/chicks","display_name":"chicks","score":0.4429999887943268},{"id":"https://openalex.org/keywords/cattle","display_name":"cattle","score":0.6299999952316284},{"id":"https://openalex.org/keywords/avian","display_name":"avian","score":0.8199999928474426},{"id":"https://openalex.org/keywords/hormone-specificity","display_name":"hormone specificity","score":0.47099998593330383},{"id":"https://openalex.org/keywords/target-organs","display_name":"target organs","score":0.5600000023841858}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8899229764938354},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8857202529907227},{"id":"https://openalex.org/C2781208988","wikidata":"https://www.wikidata.org/wiki/Q202476","display_name":"Parathyroid hormone","level":3,"score":0.6934743523597717},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.6721177697181702},{"id":"https://openalex.org/C2778525890","wikidata":"https://www.wikidata.org/wiki/Q184564","display_name":"Aldosterone","level":2,"score":0.6419872045516968},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.5593314170837402},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.5098142027854919},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.4975931942462921},{"id":"https://openalex.org/C2780352252","wikidata":"https://www.wikidata.org/wiki/Q422543","display_name":"Corticosterone","level":3,"score":0.4749962091445923},{"id":"https://openalex.org/C177865409","wikidata":"https://www.wikidata.org/wiki/Q410784","display_name":"ACTH receptor","level":4,"score":0.4569026529788971},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4538721442222595},{"id":"https://openalex.org/C2776888042","wikidata":"https://www.wikidata.org/wiki/Q422137","display_name":"Steroid hormone","level":3,"score":0.4268896281719208},{"id":"https://openalex.org/C2780694816","wikidata":"https://www.wikidata.org/wiki/Q712294","display_name":"Adrenal gland","level":2,"score":0.42244717478752136},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4176594913005829},{"id":"https://openalex.org/C2780546910","wikidata":"https://www.wikidata.org/wiki/Q185690","display_name":"Adrenocorticotropic hormone","level":3,"score":0.3687317371368408},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.2215876281261444},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18360450863838196}],"mesh":[{"descriptor_ui":"D000242","descriptor_name":"Cyclic AMP","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D000311","descriptor_name":"Adrenal Glands","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D000311","descriptor_name":"Adrenal Glands","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D000311","descriptor_name":"Adrenal Glands","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000324","descriptor_name":"Adrenocorticotropic Hormone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002645","descriptor_name":"Chickens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010281","descriptor_name":"Parathyroid Hormone","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D010281","descriptor_name":"Parathyroid Hormone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1677/joe.0.1120431","doi":"https://doi.org/10.1677/joe.0.1120431","is_oa":false,"landing_page_url":"https://doi.org/10.1677/joe.0.1120431","pdf_url":null,"source":{"id":"https://openalex.org/S34842069","display_name":"Journal of Endocrinology","issn_l":"0022-0795","issn":["0022-0795","1479-6805"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319937","host_organization_name":"Bioscientifica","host_organization_lineage":["https://openalex.org/P4310319937"],"host_organization_lineage_names":["Bioscientifica"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Endocrinology","raw_type":"journal-article"},{"id":"pmid:3031192","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3031192","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of endocrinology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320308883","display_name":"United States - Israel Binational Agricultural Research and Development Fund","ror":"https://ror.org/04e98j339"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2018628991","https://openalex.org/W1986724241","https://openalex.org/W1969228940","https://openalex.org/W2024510307","https://openalex.org/W2165014588","https://openalex.org/W1995613628","https://openalex.org/W2169518699","https://openalex.org/W2108495350","https://openalex.org/W2080153188","https://openalex.org/W2069652604"],"abstract_inverted_index":{"Dispersed":[0],"adrenal":[1,180,188],"cells":[2,33,62,87,181],"of":[3,64,84,95,102,157],"avian":[4,21,68,85,161,179],"and":[5,24,44,48,67,140,149,176,195],"bovine":[6,17,60,66],"origin":[7,69],"were":[8,36,51],"incubated":[9],"with":[10,25,168],"human":[11],"(h)":[12],"1-34":[13],"parathyroid":[14],"hormone":[15,46,114],"(PTH(1-34)),":[16],"(b)":[18],"PTH(1-84),":[19],"bPTH(3-34),":[20],"(a)":[22],"PTH,":[23,35,194],"ACTH.":[26,208],"Kidney":[27],"tubular":[28],"cells,":[29,120,148,163],"the":[30,56,59,74,117,122,133,150,187,198],"established":[31],"target":[32,191],"for":[34,38,193,207],"used":[37],"comparison.":[39],"Cyclic":[40],"AMP":[41],"(cAMP)":[42],"accumulation":[43,159],"steroid":[45,113],"(aldosterone":[47],"corticosterone)":[49],"secretion":[50,115,124],"measured":[52],"in":[53,116,135,146,160,178],"response":[54,83],"to":[55,88,106,127],"hormones.":[57],"In":[58],"adrenocortical":[61,86,119,162],"PTH":[63,111,199],"both":[65],"stimulated":[70,112,143],"cAMP":[71,82,136,144,158,172],"production,":[72],"but":[73,97,121,164],"aPTH":[75,89,103,155,175],"action":[76],"was":[77,90,104,125,182],"more":[78],"pronounced.":[79],"The":[80,184],"maximal":[81],"15-fold":[91],"greater":[92],"than":[93],"that":[94,128,197],"ACTH,":[96,131],"a":[98,190],"20-times":[99],"higher":[100],"concentration":[101],"required":[105],"reach":[107],"half-maximal":[108],"response.":[109],"Avian":[110],"chick":[118],"induced":[123,129],"similar":[126],"by":[130,174],"despite":[132],"difference":[134],"accumulation.":[137],"Human":[138],"PTH(1-34)":[139],"bPTH(1-84),":[141],"which":[142],"production":[145],"kidney":[147],"conventional":[151],"antagonist":[152],"bPTH(3-34)":[153],"inhibited":[154],"stimulation":[156,173],"did":[165],"not":[166],"interfere":[167],"ACTH":[169,177],"action.":[170],"Furthermore,":[171],"additive.":[183],"results":[185],"establish":[186],"as":[189],"organ":[192],"suggest":[196],"acts":[200],"through":[201],"specific":[202],"receptors,":[203],"distinct":[204],"from":[205],"those":[206]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}