{"id":"https://openalex.org/W2014064429","doi":"https://doi.org/10.3109/10606820490514969","title":"BacMam Recombinant Baculoviruses in G Protein?Coupled Receptor Drug Discovery","display_name":"BacMam Recombinant Baculoviruses in G Protein?Coupled Receptor Drug Discovery","publication_year":2004,"publication_date":"2004-01-01","ids":{"openalex":"https://openalex.org/W2014064429","doi":"https://doi.org/10.3109/10606820490514969","mag":"2014064429","pmid":"https://pubmed.ncbi.nlm.nih.gov/15512844"},"language":"en","primary_location":{"id":"doi:10.3109/10606820490514969","doi":"https://doi.org/10.3109/10606820490514969","is_oa":false,"landing_page_url":"https://doi.org/10.3109/10606820490514969","pdf_url":null,"source":{"id":"https://openalex.org/S170807220","display_name":"Receptors and Channels","issn_l":"1060-6823","issn":["1060-6823","1543-5334","1607-856X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Receptors and Channels","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044755005","display_name":"Robert S. Ames","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114143","display_name":"GlaxoSmithKline (United States)","ror":"https://ror.org/025vn3989","country_code":"US","type":"company","lineage":["https://openalex.org/I188950975","https://openalex.org/I4210114143"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Ames","raw_affiliation_strings":["Gene Expression & Protein Biochemisty, Discovery Research Biology, GlaxoSmithKline, King of Prussia, PA 19406-0939, USA. bob.ames@gsk.com","Gene Expression & Protein Biochemisty, Discovery Research Biology, GlaxoSmithKline, King of Prussia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gene Expression & Protein Biochemisty, Discovery Research Biology, GlaxoSmithKline, King of Prussia, PA 19406-0939, USA. bob.ames@gsk.com","institution_ids":["https://openalex.org/I4210114143"]},{"raw_affiliation_string":"Gene Expression & Protein Biochemisty, Discovery Research Biology, GlaxoSmithKline, King of Prussia, PA, USA","institution_ids":["https://openalex.org/I4210114143"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026471007","display_name":"James A. Fornwald","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114143","display_name":"GlaxoSmithKline (United States)","ror":"https://ror.org/025vn3989","country_code":"US","type":"company","lineage":["https://openalex.org/I188950975","https://openalex.org/I4210114143"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James Fornwald","raw_affiliation_strings":["Gene Expression & Protein Biochemisty, Discovery Research Biology, GlaxoSmithKline, King of Prussia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gene Expression & Protein Biochemisty, Discovery Research Biology, GlaxoSmithKline, King of Prussia, PA, USA","institution_ids":["https://openalex.org/I4210114143"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021673021","display_name":"Parvathi Nuthulaganti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114143","display_name":"GlaxoSmithKline (United States)","ror":"https://ror.org/025vn3989","country_code":"US","type":"company","lineage":["https://openalex.org/I188950975","https://openalex.org/I4210114143"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Parvathi Nuthulaganti","raw_affiliation_strings":["Gene Expression & Protein Biochemisty, Discovery Research Biology, GlaxoSmithKline, King of Prussia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gene Expression & Protein Biochemisty, Discovery Research Biology, GlaxoSmithKline, King of Prussia, PA, USA","institution_ids":["https://openalex.org/I4210114143"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077005478","display_name":"John J. Trill","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114143","display_name":"GlaxoSmithKline (United States)","ror":"https://ror.org/025vn3989","country_code":"US","type":"company","lineage":["https://openalex.org/I188950975","https://openalex.org/I4210114143"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John Trill","raw_affiliation_strings":["Gene Expression & Protein Biochemisty, Discovery Research Biology, GlaxoSmithKline, King of Prussia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gene Expression & Protein Biochemisty, Discovery Research Biology, GlaxoSmithKline, King of Prussia, PA, USA","institution_ids":["https://openalex.org/I4210114143"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035407065","display_name":"James J. Foley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114143","display_name":"GlaxoSmithKline (United States)","ror":"https://ror.org/025vn3989","country_code":"US","type":"company","lineage":["https://openalex.org/I188950975","https://openalex.org/I4210114143"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James Foley","raw_affiliation_strings":["Respiratory and Inflammation Center of Excellence for Drug Discovery, GlaxoSmithKline, King of Prussia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Respiratory and Inflammation Center of Excellence for Drug Discovery, GlaxoSmithKline, King of Prussia, PA, USA","institution_ids":["https://openalex.org/I4210114143"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090468389","display_name":"Peter T. Buckley","orcid":"https://orcid.org/0009-0005-1194-3615","observed_orcids":["https://orcid.org/0009-0005-1194-3615"]},"institutions":[{"id":"https://openalex.org/I4210114143","display_name":"GlaxoSmithKline (United States)","ror":"https://ror.org/025vn3989","country_code":"US","type":"company","lineage":["https://openalex.org/I188950975","https://openalex.org/I4210114143"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter Buckley","raw_affiliation_strings":["Respiratory and Inflammation Center of Excellence for Drug Discovery, GlaxoSmithKline, King of Prussia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Respiratory and Inflammation Center of Excellence for Drug Discovery, GlaxoSmithKline, King of Prussia, PA, USA","institution_ids":["https://openalex.org/I4210114143"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111468781","display_name":"Thomas A. Kost","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210114143","display_name":"GlaxoSmithKline (United States)","ror":"https://ror.org/025vn3989","country_code":"US","type":"company","lineage":["https://openalex.org/I188950975","https://openalex.org/I4210114143"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas Kost","raw_affiliation_strings":["Gene Expression & Protein Biochemisty, Discovery Research Biology, GlaxoSmithKline, Research Triangle Park, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gene Expression & Protein Biochemisty, Discovery Research Biology, GlaxoSmithKline, Research Triangle Park, NC, USA","institution_ids":["https://openalex.org/I4210114143"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112418914","display_name":"Zining Wu","orcid":"https://orcid.org/0009-0001-5155-7285","observed_orcids":["https://orcid.org/0009-0001-5155-7285"]},"institutions":[{"id":"https://openalex.org/I4210114143","display_name":"GlaxoSmithKline (United States)","ror":"https://ror.org/025vn3989","country_code":"US","type":"company","lineage":["https://openalex.org/I188950975","https://openalex.org/I4210114143"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zining Wu","raw_affiliation_strings":["Assay Development & Compound Profiling, Discovery Research Biology, GlaxoSmithKline, Collegeville, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Assay Development & Compound Profiling, Discovery Research Biology, GlaxoSmithKline, Collegeville, PA, USA","institution_ids":["https://openalex.org/I4210114143"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111632631","display_name":"Michael A. Romanos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I188950975","display_name":"GlaxoSmithKline (United Kingdom)","ror":"https://ror.org/01xsqw823","country_code":"GB","type":"company","lineage":["https://openalex.org/I188950975"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Michael Romanos","raw_affiliation_strings":["Gene Expression & Protein Biochemisty, Discovery Research Biology, GlaxoSmithKline, Stevenage, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gene Expression & Protein Biochemisty, Discovery Research Biology, GlaxoSmithKline, Stevenage, UK","institution_ids":["https://openalex.org/I188950975"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.2447,"has_fulltext":false,"cited_by_count":56,"citation_normalized_percentile":{"value":0.87806956,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"10","issue":"3-4","first_page":"99","last_page":"107"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9307000041007996,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9307000041007996,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.05050000175833702,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/recombinant-baculovirus","display_name":"recombinant baculovirus","score":0.9959999918937683},{"id":"https://openalex.org/keywords/g-protein-coupled-receptors","display_name":"G protein-coupled receptors","score":0.9959999918937683},{"id":"https://openalex.org/keywords/orphan-gpcrs","display_name":"orphan G protein-coupled receptor","score":0.824999988079071},{"id":"https://openalex.org/keywords/transient-expression-system","display_name":"transient expression system","score":0.7400000095367432},{"id":"https://openalex.org/keywords/gpcr-drug-discovery","display_name":"GPCR drug discovery","score":0.6800000071525574},{"id":"https://openalex.org/keywords/ligand-screening","display_name":"ligand screening","score":0.6859999895095825},{"id":"https://openalex.org/keywords/polyhedrin-promoter","display_name":"polyhedrin promoter","score":0.7519999742507935},{"id":"https://openalex.org/keywords/gene-therapy-vectors","display_name":"gene therapy vectors","score":0.6890000104904175}],"concepts":[{"id":"https://openalex.org/C135285700","wikidata":"https://www.wikidata.org/wiki/Q38173","display_name":"G protein-coupled receptor","level":3,"score":0.8483855724334717},{"id":"https://openalex.org/C2781140520","wikidata":"https://www.wikidata.org/wiki/Q24771294","display_name":"Polyhedrin","level":5,"score":0.7871483564376831},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.7530880570411682},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.7097678184509277},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5445762276649475},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.43912315368652344},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.4308728873729706},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.42365407943725586},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.37603580951690674},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2898598611354828},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2854800820350647},{"id":"https://openalex.org/C2777773057","wikidata":"https://www.wikidata.org/wiki/Q2492887","display_name":"Spodoptera","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005822","descriptor_name":"Genetic Vectors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014161","descriptor_name":"Transduction, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016367","descriptor_name":"Baculoviridae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018039","descriptor_name":"Receptors, Tachykinin","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D018039","descriptor_name":"Receptors, Tachykinin","qualifier_ui":"Q000819","qualifier_name":"agonists","is_major_topic":false},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D043562","descriptor_name":"Receptors, G-Protein-Coupled","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3109/10606820490514969","doi":"https://doi.org/10.3109/10606820490514969","is_oa":false,"landing_page_url":"https://doi.org/10.3109/10606820490514969","pdf_url":null,"source":{"id":"https://openalex.org/S170807220","display_name":"Receptors and Channels","issn_l":"1060-6823","issn":["1060-6823","1543-5334","1607-856X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Receptors and Channels","raw_type":"journal-article"},{"id":"doi:10.1080/10606820490514969","doi":"https://doi.org/10.1080/10606820490514969","is_oa":false,"landing_page_url":"https://doi.org/10.1080/10606820490514969","pdf_url":null,"source":{"id":"https://openalex.org/S170807220","display_name":"Receptors and Channels","issn_l":"1060-6823","issn":["1060-6823","1543-5334","1607-856X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Receptors and Channels","raw_type":"journal-article"},{"id":"pmid:15512844","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15512844","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Receptors & channels","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1525063665","https://openalex.org/W1967516426","https://openalex.org/W1971886200","https://openalex.org/W2020231880","https://openalex.org/W2020454474","https://openalex.org/W2023291722","https://openalex.org/W2024270675","https://openalex.org/W2027740042","https://openalex.org/W2029839079","https://openalex.org/W2053749344","https://openalex.org/W2061724477","https://openalex.org/W2074370114","https://openalex.org/W2076003033","https://openalex.org/W2085622992","https://openalex.org/W2100983960","https://openalex.org/W2106949710","https://openalex.org/W2123953194","https://openalex.org/W2133636515","https://openalex.org/W2135907817","https://openalex.org/W2150770791","https://openalex.org/W2156047261","https://openalex.org/W2259854637","https://openalex.org/W2274270616","https://openalex.org/W2334559503","https://openalex.org/W2403995597","https://openalex.org/W2477381506","https://openalex.org/W4322702926"],"related_works":["https://openalex.org/W60066734","https://openalex.org/W1502746889","https://openalex.org/W1975640964","https://openalex.org/W2024270675","https://openalex.org/W1999603524","https://openalex.org/W1974413343","https://openalex.org/W2089461791","https://openalex.org/W2041592431","https://openalex.org/W1996132104","https://openalex.org/W4254754924"],"abstract_inverted_index":{"With":[0],"completion":[1],"of":[2,5,14,65,76,99,103,119,129,177],"the":[3,6,11,31,58,63,97,140,175,204],"sequencing":[4,110],"human":[7],"and":[8,36,195],"mouse":[9],"genomes,":[10],"primary":[12],"sequences":[13,106],"close":[15],"to":[16,34,51,69,192,206],"400":[17],"non-olfactory":[18],"G":[19],"protein-coupled":[20],"receptors":[21,73],"(GPCRs)":[22],"have":[23],"been":[24,144],"determined.":[25],"There":[26],"are":[27,88],"intensive":[28],"efforts":[29,111],"within":[30],"pharmaceutical":[32],"industry":[33],"discover":[35],"develop":[37],"new":[38,54,104,158],"therapeutic":[39],"agents":[40],"acting":[41],"via":[42],"GPCRs.":[43,182],"In":[44],"addition,":[45],"there":[46],"is":[47],"a":[48,114,147,170],"concerted":[49],"effort":[50],"identify":[52],"potential":[53,157,205],"drug":[55,79,84,179,208],"targets":[56],"from":[57,108],"remaining":[59],"150+orphan":[60],"GPCRs":[61],"through":[62],"identification":[64],"their":[66],"ligands.":[67],"Access":[68],"functionally":[70],"expressed":[71],"recombinant":[72],"underpins":[74],"both":[75],"these":[77],"key":[78],"discovery":[80,85,209],"activities.":[81],"Typically,":[82],"GPCR":[83,198],"screening":[86,210],"activities":[87],"carried":[89],"out":[90],"using":[91],"mammalian":[92,148],"cell":[93],"lines":[94],"stably":[95],"expressing":[96],"target":[98],"interest.":[100],"The":[101],"influx":[102],"receptor":[105,133],"originating":[107],"genomic":[109],"has":[112,143],"caused":[113],"shift":[115],"toward":[116],"wider":[117],"applications":[118],"transient":[120,171],"rather":[121],"than":[122],"stable":[123],"expression":[124,172],"systems,":[125],"especially":[126],"in":[127,138,174,200],"support":[128],"assays":[130,199],"for":[131,212],"orphan":[132],"ligand":[134],"screening.":[135],"Recombinant":[136],"baculoviruses":[137],"which":[139],"polyhedrin":[141],"promoter":[142],"replaced":[145],"with":[146,203],"promoter,":[149],"termed":[150],"BacMam":[151,187],"viruses,":[152],"were":[153],"originally":[154],"designed":[155],"as":[156,169],"gene":[159,214],"therapy":[160],"delivery":[161],"vehicles.":[162],"This":[163],"same":[164],"technology":[165],"offers":[166],"numerous":[167],"advantages":[168],"system":[173],"assay":[176],"membrane-expressed":[178],"targets,":[180],"including":[181],"Data":[183],"presented":[184],"show":[185],"that":[186],"can":[188],"be":[189],"used":[190],"rapidly":[191],"generate":[193],"robust":[194],"pharmacologically":[196],"authentic":[197],"several":[201],"formats,":[202],"transform":[207],"processes":[211],"this":[213],"family.":[215]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}