{"id":"https://openalex.org/W2014034337","doi":"https://doi.org/10.1271/bbb.67.951","title":"Decrease in Ovalbumin Specific IgE of Mice Serum after Oral Uptake of Lactic Acid Bacteria","display_name":"Decrease in Ovalbumin Specific IgE of Mice Serum after Oral Uptake of Lactic Acid Bacteria","publication_year":2003,"publication_date":"2003-01-01","ids":{"openalex":"https://openalex.org/W2014034337","doi":"https://doi.org/10.1271/bbb.67.951","mag":"2014034337","pmid":"https://pubmed.ncbi.nlm.nih.gov/12834270"},"language":"en","primary_location":{"id":"doi:10.1271/bbb.67.951","doi":"https://doi.org/10.1271/bbb.67.951","is_oa":false,"landing_page_url":"https://doi.org/10.1271/bbb.67.951","pdf_url":null,"source":{"id":"https://openalex.org/S94095188","display_name":"Bioscience Biotechnology and Biochemistry","issn_l":"0916-8451","issn":["0916-8451","1347-6947"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioscience, Biotechnology, and Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074786139","display_name":"Yuu ISHIDA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405263881","display_name":"Calpis Co., Ltd. (Japan)","ror":"https://ror.org/00a9d5922","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405263881"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuu ISHIDA","raw_affiliation_strings":["R&D Center, Calpis Co., Ltd., 11-10, 5-Chome, Fuchinobe, Sagamihara, Kanagawa 229-0006, Japan","Center, Calpis Co., Ltd.11-10, 5-Chome, Fuchinobe, Sagamihara, Kanagawa 229-0006, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"R&D Center, Calpis Co., Ltd., 11-10, 5-Chome, Fuchinobe, Sagamihara, Kanagawa 229-0006, Japan","institution_ids":["https://openalex.org/I4405263881"]},{"raw_affiliation_string":"Center, Calpis Co., Ltd.11-10, 5-Chome, Fuchinobe, Sagamihara, Kanagawa 229-0006, Japan","institution_ids":["https://openalex.org/I4405263881"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035429505","display_name":"Izuki BANDOU","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405263881","display_name":"Calpis Co., Ltd. (Japan)","ror":"https://ror.org/00a9d5922","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405263881"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Izuki BANDOU","raw_affiliation_strings":["R&D; Center, Calpis Co., Ltd. 11-10, 5-Chome, Fuchinobe, Sagamihara, Kanagawa 229-0006, Japan","Center, Calpis Co., Ltd.11-10, 5-Chome, Fuchinobe, Sagamihara, Kanagawa 229-0006, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"R&D; Center, Calpis Co., Ltd. 11-10, 5-Chome, Fuchinobe, Sagamihara, Kanagawa 229-0006, Japan","institution_ids":["https://openalex.org/I4405263881"]},{"raw_affiliation_string":"Center, Calpis Co., Ltd.11-10, 5-Chome, Fuchinobe, Sagamihara, Kanagawa 229-0006, Japan","institution_ids":["https://openalex.org/I4405263881"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007352121","display_name":"Hiroki Kanzato","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405263881","display_name":"Calpis Co., Ltd. (Japan)","ror":"https://ror.org/00a9d5922","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405263881"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroki KANZATO","raw_affiliation_strings":["R&D; Center, Calpis Co., Ltd. 11-10, 5-Chome, Fuchinobe, Sagamihara, Kanagawa 229-0006, Japan","Center, Calpis Co., Ltd.11-10, 5-Chome, Fuchinobe, Sagamihara, Kanagawa 229-0006, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"R&D; Center, Calpis Co., Ltd. 11-10, 5-Chome, Fuchinobe, Sagamihara, Kanagawa 229-0006, Japan","institution_ids":["https://openalex.org/I4405263881"]},{"raw_affiliation_string":"Center, Calpis Co., Ltd.11-10, 5-Chome, Fuchinobe, Sagamihara, Kanagawa 229-0006, Japan","institution_ids":["https://openalex.org/I4405263881"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019741169","display_name":"Naoyuki Yamamoto","orcid":"https://orcid.org/0000-0001-6546-1404","observed_orcids":["https://orcid.org/0000-0001-6546-1404"]},"institutions":[{"id":"https://openalex.org/I4405263881","display_name":"Calpis Co., Ltd. (Japan)","ror":"https://ror.org/00a9d5922","country_code":"JP","type":"company","lineage":["https://openalex.org/I4405263881"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naoyuki YAMAMOTO","raw_affiliation_strings":["R&D; Center, Calpis Co., Ltd. 11-10, 5-Chome, Fuchinobe, Sagamihara, Kanagawa 229-0006, Japan","Center, Calpis Co., Ltd.11-10, 5-Chome, Fuchinobe, Sagamihara, Kanagawa 229-0006, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"R&D; Center, Calpis Co., Ltd. 11-10, 5-Chome, Fuchinobe, Sagamihara, Kanagawa 229-0006, Japan","institution_ids":["https://openalex.org/I4405263881"]},{"raw_affiliation_string":"Center, Calpis Co., Ltd.11-10, 5-Chome, Fuchinobe, Sagamihara, Kanagawa 229-0006, Japan","institution_ids":["https://openalex.org/I4405263881"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4405263881"],"apc_list":{"value":3272,"currency":"USD","value_usd":3272},"apc_paid":null,"fwci":4.7411,"has_fulltext":true,"cited_by_count":62,"citation_normalized_percentile":{"value":0.93933759,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"67","issue":"5","first_page":"951","last_page":"957"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ovalbumin-specific-ige","display_name":"ovalbumin-specific IgE","score":0.9959999918937683},{"id":"https://openalex.org/keywords/lactic-acid-bacteria","display_name":"lactic acid bacteria","score":0.9150000214576721},{"id":"https://openalex.org/keywords/fermented-milk","display_name":"fermented milk","score":0.9769999980926514},{"id":"https://openalex.org/keywords/lactobacillus-acidophilus","display_name":"Lactobacillus acidophilus","score":0.9620000123977661},{"id":"https://openalex.org/keywords/limosilactobacillus-fermentum","display_name":"Lactobacillus fermentum","score":0.9990000128746033},{"id":"https://openalex.org/keywords/bifidobacterium","display_name":"Bifidobacterium","score":0.9490000009536743},{"id":"https://openalex.org/keywords/oral-administration","display_name":"oral administration","score":0.7559999823570251},{"id":"https://openalex.org/keywords/gastrointestinal-colonization","display_name":"intestinal colonization","score":0.3790000081062317},{"id":"https://openalex.org/keywords/food-allergy","display_name":"food allergy","score":0.3499999940395355}],"concepts":[{"id":"https://openalex.org/C2776503186","wikidata":"https://www.wikidata.org/wiki/Q2134039","display_name":"Lactobacillus fermentum","level":5,"score":0.9350879192352295},{"id":"https://openalex.org/C2777221637","wikidata":"https://www.wikidata.org/wiki/Q132644","display_name":"Lactobacillus acidophilus","level":4,"score":0.8333526849746704},{"id":"https://openalex.org/C2776946954","wikidata":"https://www.wikidata.org/wiki/Q420291","display_name":"Ovalbumin","level":3,"score":0.8157380223274231},{"id":"https://openalex.org/C141105273","wikidata":"https://www.wikidata.org/wiki/Q79455","display_name":"Immunoglobulin E","level":3,"score":0.7005478143692017},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5012176036834717},{"id":"https://openalex.org/C2775920511","wikidata":"https://www.wikidata.org/wiki/Q161249","display_name":"Lactic acid","level":3,"score":0.48374485969543457},{"id":"https://openalex.org/C100544194","wikidata":"https://www.wikidata.org/wiki/Q41760","display_name":"Fermentation","level":2,"score":0.46398356556892395},{"id":"https://openalex.org/C2780206646","wikidata":"https://www.wikidata.org/wiki/Q1061596","display_name":"Lactobacillus","level":3,"score":0.4625749886035919},{"id":"https://openalex.org/C2780437316","wikidata":"https://www.wikidata.org/wiki/Q578677","display_name":"Lactobacillaceae","level":4,"score":0.4503940939903259},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4242875874042511},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.41130968928337097},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.3462664484977722},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33006513118743896},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2951465845108032},{"id":"https://openalex.org/C2780255968","wikidata":"https://www.wikidata.org/wiki/Q1816730","display_name":"Probiotic","level":3,"score":0.2856783866882324},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.23189595341682434},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.18189868330955505},{"id":"https://openalex.org/C2778985185","wikidata":"https://www.wikidata.org/wiki/Q1756682","display_name":"Lactobacillus plantarum","level":4,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001422","descriptor_name":"Bacterial Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001644","descriptor_name":"Bifidobacterium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003470","descriptor_name":"Culture Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004064","descriptor_name":"Digestive System","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005285","descriptor_name":"Fermentation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007073","descriptor_name":"Immunoglobulin E","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007778","descriptor_name":"Lactobacillus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007779","descriptor_name":"Lactobacillus acidophilus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008892","descriptor_name":"Milk","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D010047","descriptor_name":"Ovalbumin","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D019344","descriptor_name":"Lactic Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1271/bbb.67.951","doi":"https://doi.org/10.1271/bbb.67.951","is_oa":false,"landing_page_url":"https://doi.org/10.1271/bbb.67.951","pdf_url":null,"source":{"id":"https://openalex.org/S94095188","display_name":"Bioscience Biotechnology and Biochemistry","issn_l":"0916-8451","issn":["0916-8451","1347-6947"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioscience, Biotechnology, and Biochemistry","raw_type":"journal-article"},{"id":"pmid:12834270","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12834270","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioscience, biotechnology, and biochemistry","raw_type":"Journal Article"},{"id":"pmh:oai:irdb.nii.ac.jp:00897:0003959007","doi":null,"is_oa":false,"landing_page_url":"http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100755315","pdf_url":null,"source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biosci Biotechnol Biochem.","raw_type":"journal article"},{"id":"pmh:oai:t2r2.star.titech.ac.jp:50395019","doi":null,"is_oa":false,"landing_page_url":"http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100755315","pdf_url":null,"source":{"id":"https://openalex.org/S4377196385","display_name":"Tokyo Tech Research Repository (Tokyo Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114531698","host_organization_name":"Tokyo Institute of Technology","host_organization_lineage":["https://openalex.org/I114531698"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9074000120162964}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W381368238","https://openalex.org/W1579612675","https://openalex.org/W1896084611","https://openalex.org/W1941587249","https://openalex.org/W1965265555","https://openalex.org/W1987484374","https://openalex.org/W1997864145","https://openalex.org/W2025737611","https://openalex.org/W2031205409","https://openalex.org/W2045847358","https://openalex.org/W2099357815","https://openalex.org/W2110765275","https://openalex.org/W2116839692","https://openalex.org/W2133439477","https://openalex.org/W2136848239","https://openalex.org/W2159175410","https://openalex.org/W2160829089","https://openalex.org/W2163014292","https://openalex.org/W4230664740"],"related_works":["https://openalex.org/W2051581105","https://openalex.org/W7144802126","https://openalex.org/W2092262276","https://openalex.org/W2371844334","https://openalex.org/W2035149606","https://openalex.org/W2031205409","https://openalex.org/W4306169030","https://openalex.org/W2374319896","https://openalex.org/W2393956547","https://openalex.org/W1747592037"],"abstract_inverted_index":{"Different":[0],"kinds":[1],"of":[2,40,73,113,123,142,155],"lactobacilli":[3],"and":[4,17,62,89,117,129,138],"Bifidobacteria":[5],"fermented":[6,66],"milk":[7,67],"were":[8,31,150],"fed":[9],"to":[10,33,81,108],"ovalbumin-specific":[11,25,51,77,97],"IgE-elevated":[12],"mice":[13],"for":[14,28,36],"3":[15],"days,":[16],"after":[18,147],"the":[19,24,34,41,49,69,75,111,124,135,139,143,153],"final":[20],"administration,":[21],"changes":[22],"in":[23,48,110],"IgE":[26,52,78,98],"values":[27],"each":[29],"sample":[30],"compared":[32,80],"value":[35],"non-fermented":[37],"milk.":[38],"Seven":[39],"Lactobacillus-fermented":[42],"milks":[43],"caused":[44],"a":[45,82],"significant":[46,71,96],"decrease":[47],"serum":[50,76],"levels.":[53],"Above":[54],"all,":[55],"Lactobacillus":[56,59,63],"acidophilus":[57,60,87,115,127],"L92,":[58],"CP1613,":[61],"fermentum":[64,91,119,131],"CP34":[65,92,120,132],"had":[68],"most":[70],"effects":[72],"decreasing":[74],"levels":[79],"control":[83],"group.":[84],"The":[85],"L.":[86,90,114,118,126,130],"L92":[88,116,128],"cells":[93,112,133],"also":[94],"showed":[95],"lowering":[99],"activities.":[100],"From":[101],"these":[102],"results,":[103],"an":[104],"active":[105],"component":[106],"seems":[107],"exist":[109],"strains.":[121],"Recovery":[122],"radiolabeled":[125],"from":[134],"small":[136],"intestine":[137,141],"large":[140],"mouse":[144],"13":[145],"h":[146],"oral":[148],"administration":[149],"higher":[151],"than":[152],"recovery":[154],"any":[156],"other":[157],"strain.":[158]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}