{"id":"https://openalex.org/W2013979837","doi":"https://doi.org/10.1111/j.1462-5822.2005.00608.x","title":"Chlamydia trachomatis enters a viable but non-cultivable (persistent) state within herpes simplex virus type 2 (HSV-2) co-infected host cells","display_name":"Chlamydia trachomatis enters a viable but non-cultivable (persistent) state within herpes simplex virus type 2 (HSV-2) co-infected host cells","publication_year":2005,"publication_date":"2005-11-08","ids":{"openalex":"https://openalex.org/W2013979837","doi":"https://doi.org/10.1111/j.1462-5822.2005.00608.x","mag":"2013979837","pmid":"https://pubmed.ncbi.nlm.nih.gov/16367874"},"language":"en","primary_location":{"id":"doi:10.1111/j.1462-5822.2005.00608.x","doi":"https://doi.org/10.1111/j.1462-5822.2005.00608.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1462-5822.2005.00608.x","pdf_url":null,"source":{"id":"https://openalex.org/S113048938","display_name":"Cellular Microbiology","issn_l":"1462-5814","issn":["1462-5814","1462-5822"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","norway-1","poland-140","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010684827","display_name":"Srilekha Deka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I119443389","display_name":"East Tennessee State University","ror":"https://ror.org/05rfqv493","country_code":"US","type":"education","lineage":["https://openalex.org/I119443389"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Srilekha Deka","raw_affiliation_strings":["Department of Microbiology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA","institution_ids":["https://openalex.org/I119443389"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077755938","display_name":"Jennifer Vanover","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I119443389","display_name":"East Tennessee State University","ror":"https://ror.org/05rfqv493","country_code":"US","type":"education","lineage":["https://openalex.org/I119443389"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer Vanover","raw_affiliation_strings":["Department of Microbiology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA","institution_ids":["https://openalex.org/I119443389"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024652458","display_name":"Sophie Dessus-Babus","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I119443389","display_name":"East Tennessee State University","ror":"https://ror.org/05rfqv493","country_code":"US","type":"education","lineage":["https://openalex.org/I119443389"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sophie Dessus-Babus","raw_affiliation_strings":["Department of Microbiology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA","institution_ids":["https://openalex.org/I119443389"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034528640","display_name":"Judy D. Whittimore","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I119443389","display_name":"East Tennessee State University","ror":"https://ror.org/05rfqv493","country_code":"US","type":"education","lineage":["https://openalex.org/I119443389"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Judy Whittimore","raw_affiliation_strings":["Department of Microbiology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA","institution_ids":["https://openalex.org/I119443389"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060274748","display_name":"Mary K. Howett","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I72816309","display_name":"Drexel University","ror":"https://ror.org/04bdffz58","country_code":"US","type":"education","lineage":["https://openalex.org/I72816309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary K. Howett","raw_affiliation_strings":["Department of Bioscience and Biotechnology, Drexel University, Philadelphia, PA, USA","Department of Bioscience & Biotechnology, Drexel University, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioscience and Biotechnology, Drexel University, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I72816309"]},{"raw_affiliation_string":"Department of Bioscience & Biotechnology, Drexel University, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I72816309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005626269","display_name":"Priscilla B. Wyrick","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I119443389","display_name":"East Tennessee State University","ror":"https://ror.org/05rfqv493","country_code":"US","type":"education","lineage":["https://openalex.org/I119443389"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Priscilla B. Wyrick","raw_affiliation_strings":["Department of Microbiology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA","institution_ids":["https://openalex.org/I119443389"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008110935","display_name":"Robert V. Schoborg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I119443389","display_name":"East Tennessee State University","ror":"https://ror.org/05rfqv493","country_code":"US","type":"education","lineage":["https://openalex.org/I119443389"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Robert V. Schoborg","raw_affiliation_strings":["Department of Microbiology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA","institution_ids":["https://openalex.org/I119443389"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5008110935"],"corresponding_institution_ids":["https://openalex.org/I119443389"],"apc_list":{"value":2350,"currency":"USD","value_usd":2350},"apc_paid":null,"fwci":3.0697,"has_fulltext":false,"cited_by_count":89,"citation_normalized_percentile":{"value":0.89484431,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"8","issue":"1","first_page":"149","last_page":"162"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.9067000150680542,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.9067000150680542,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.05990000069141388,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chlamydia-trachomatis","display_name":"Chlamydia trachomatis","score":1.0},{"id":"https://openalex.org/keywords/herpes-simplex-virus-type-2","display_name":"herpes simplex virus type 2","score":0.9649999737739563},{"id":"https://openalex.org/keywords/coinfection","display_name":"co-infection","score":0.875},{"id":"https://openalex.org/keywords/viable-but-non-culturable-state","display_name":"viable but nonculturable state","score":0.8349999785423279},{"id":"https://openalex.org/keywords/chlamydial-persistence","display_name":"chlamydial persistence","score":0.925000011920929},{"id":"https://openalex.org/keywords/reticulate-bodies","display_name":"reticulate bodies","score":0.9089999794960022},{"id":"https://openalex.org/keywords/major-outer-membrane-protein","display_name":"major outer membrane protein","score":0.9279999732971191},{"id":"https://openalex.org/keywords/hela-cells","display_name":"HeLa cells","score":0.6359999775886536},{"id":"https://openalex.org/keywords/genital-tract-infection","display_name":"genital tract infection","score":0.3240000009536743}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9105900526046753},{"id":"https://openalex.org/C2777391075","wikidata":"https://www.wikidata.org/wiki/Q131065","display_name":"Chlamydia trachomatis","level":2,"score":0.7811968326568604},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.7580447196960449},{"id":"https://openalex.org/C2779204014","wikidata":"https://www.wikidata.org/wiki/Q875679","display_name":"Chlamydiae","level":3,"score":0.6917641758918762},{"id":"https://openalex.org/C2781196997","wikidata":"https://www.wikidata.org/wiki/Q655331","display_name":"Herpes simplex virus","level":3,"score":0.650568962097168},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5465065240859985},{"id":"https://openalex.org/C2779617845","wikidata":"https://www.wikidata.org/wiki/Q1563808","display_name":"Superinfection","level":3,"score":0.5033580660820007},{"id":"https://openalex.org/C2777667758","wikidata":"https://www.wikidata.org/wiki/Q134275","display_name":"Chlamydia psittaci","level":3,"score":0.46308332681655884},{"id":"https://openalex.org/C2777038808","wikidata":"https://www.wikidata.org/wiki/Q13474598","display_name":"Chlamydiaceae","level":3,"score":0.44387373328208923},{"id":"https://openalex.org/C89138240","wikidata":"https://www.wikidata.org/wiki/Q3066564","display_name":"Vero cell","level":3,"score":0.41524362564086914},{"id":"https://openalex.org/C2780122209","wikidata":"https://www.wikidata.org/wiki/Q153356","display_name":"Chlamydia","level":2,"score":0.40864062309265137},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.4075995683670044},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.1939358413219452}],"mesh":[{"descriptor_ui":"D001425","descriptor_name":"Bacterial Outer Membrane Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002690","descriptor_name":"Chlamydia Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D002690","descriptor_name":"Chlamydia Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D002692","descriptor_name":"Chlamydia trachomatis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002692","descriptor_name":"Chlamydia trachomatis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002692","descriptor_name":"Chlamydia trachomatis","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006558","descriptor_name":"Herpes Genitalis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006558","descriptor_name":"Herpes Genitalis","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012329","descriptor_name":"RNA, Bacterial","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012336","descriptor_name":"RNA, Ribosomal, 16S","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015163","descriptor_name":"Superinfection","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D015163","descriptor_name":"Superinfection","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D018258","descriptor_name":"Herpesvirus 2, Human","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D018258","descriptor_name":"Herpesvirus 2, Human","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D018628","descriptor_name":"Gene Dosage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018834","descriptor_name":"Chaperonin 60","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D046529","descriptor_name":"Microscopy, Electron, Transmission","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1111/j.1462-5822.2005.00608.x","doi":"https://doi.org/10.1111/j.1462-5822.2005.00608.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1462-5822.2005.00608.x","pdf_url":null,"source":{"id":"https://openalex.org/S113048938","display_name":"Cellular Microbiology","issn_l":"1462-5814","issn":["1462-5814","1462-5822"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","norway-1","poland-140","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular Microbiology","raw_type":"journal-article"},{"id":"pmid:16367874","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16367874","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cellular microbiology","raw_type":"Journal Article"},{"id":"pmh:oai:dc.etsu.edu:etsu-works-19556","doi":null,"is_oa":false,"landing_page_url":"https://dc.etsu.edu/etsu-works/18290","pdf_url":null,"source":{"id":"https://openalex.org/S4377196424","display_name":"Digital Commons - East Tennessee State University (East Tennessee State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I119443389","host_organization_name":"East Tennessee State University","host_organization_lineage":["https://openalex.org/I119443389"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ETSU Faculty Works","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8299999833106995}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5149015620","display_name":null,"funder_award_id":"P01-AI-37829-08","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G6279044127","display_name":"INDUCTION OF CHLAMYDIAL PERSISTENCE BY HSV-2","funder_award_id":"R21AI059563","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G748652274","display_name":"MICROBICIDES IN MODEL SYSTEMS","funder_award_id":"P01AI037829","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320333834","display_name":"Quillen College of Medicine, East Tennessee State University","ror":null},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W1683303276","https://openalex.org/W1820383529","https://openalex.org/W1848655996","https://openalex.org/W1878895457","https://openalex.org/W1892959235","https://openalex.org/W1893839380","https://openalex.org/W1895723152","https://openalex.org/W1900578928","https://openalex.org/W1941799273","https://openalex.org/W1947612882","https://openalex.org/W1964340993","https://openalex.org/W1964522214","https://openalex.org/W1974307119","https://openalex.org/W1983461245","https://openalex.org/W1984587054","https://openalex.org/W2004723245","https://openalex.org/W2006793799","https://openalex.org/W2008099978","https://openalex.org/W2019621674","https://openalex.org/W2024639715","https://openalex.org/W2026194709","https://openalex.org/W2027790642","https://openalex.org/W2035096887","https://openalex.org/W2035206061","https://openalex.org/W2040568845","https://openalex.org/W2047686105","https://openalex.org/W2047798559","https://openalex.org/W2047912396","https://openalex.org/W2049805694","https://openalex.org/W2057064398","https://openalex.org/W2061139863","https://openalex.org/W2070953605","https://openalex.org/W2076402993","https://openalex.org/W2078989932","https://openalex.org/W2079047282","https://openalex.org/W2079292979","https://openalex.org/W2083369434","https://openalex.org/W2083752778","https://openalex.org/W2087840674","https://openalex.org/W2090526745","https://openalex.org/W2097889231","https://openalex.org/W2104637603","https://openalex.org/W2118300475","https://openalex.org/W2139231325","https://openalex.org/W2147990979","https://openalex.org/W2148246759","https://openalex.org/W2165731327","https://openalex.org/W2168494912","https://openalex.org/W2400427207","https://openalex.org/W2414116496","https://openalex.org/W2417557835","https://openalex.org/W4211194686","https://openalex.org/W4232170885","https://openalex.org/W4247040493","https://openalex.org/W4251545571"],"related_works":["https://openalex.org/W2045224809","https://openalex.org/W7139442955","https://openalex.org/W2116968469","https://openalex.org/W7096556442","https://openalex.org/W7139598884","https://openalex.org/W2151682931","https://openalex.org/W2229135432","https://openalex.org/W2417557835","https://openalex.org/W2336806095","https://openalex.org/W2019621674"],"abstract_inverted_index":{"Epidemiological":[0],"and":[1,16,76,149],"clinical":[2],"studies":[3],"have":[4],"shown":[5],"that":[6,24,94,124,141,163,194],"double":[7],"infection":[8],"with":[9,40,186],"herpes":[10],"simplex":[11],"virus":[12],"type":[13],"2":[14],"(HSV-2)":[15],"Chlamydia":[17],"trachomatis":[18,42],"occurs":[19],"in":[20,69,188,200],"vivo.":[21],"We":[22],"hypothesized":[23],"co-infection":[25,83,107],"would":[26],"alter":[27],"replication":[28],"of":[29,86,96,110,143,178],"these":[30,190],"agents.":[31],"To":[32],"test":[33],"this":[34],"hypothesis,":[35],"HeLa":[36],"cells":[37,71],"were":[38,72,154],"infected":[39],"C.":[41],"serovar":[43],"E,":[44],"followed":[45],"24":[46],"h":[47,62],"later":[48],"by":[49,60,105,131,157],"HSV-2":[50,82,132,158,164],"strain":[51],"333.":[52],"Transmission":[53],"electron":[54],"microscopic":[55],"(TEM)":[56],"analyses":[57,92],"indicated":[58,93,123],"that,":[59],"10":[61],"after":[63],"HSV":[64,106],"addition,":[65],"reticulate":[66],"bodies":[67],"(RBs)":[68],"co-infected":[70,201],"swollen,":[73],"aberrantly":[74],"shaped":[75],"electron-lucent.":[77],"In":[78],"infectious":[79,87],"titre":[80],"assays,":[81],"abrogated":[84],"production":[85],"chlamydial":[88,97,111,125,144,181],"progeny.":[89],"Western":[90],"blot":[91],"accumulation":[95,109],"major":[98],"outer":[99],"membrane":[100],"protein":[101,113],"(MOMP)":[102],"was":[103,116,129],"decreased":[104],"while":[108],"heat-shock":[112],"60-1":[114],"(HSP60-1)":[115],"increased.":[117],"Polymerase":[118],"chain":[119],"reaction":[120],"(PCR)":[121],"experiments":[122,139],"genome":[126],"copy":[127],"number":[128],"unaltered":[130],"superinfection.":[133],"Semi-quantitative,":[134],"reverse":[135],"transcription":[136],"PCR":[137],"(RT-PCR)":[138],"demonstrated":[140],"levels":[142],"groEL,":[145],"ftsK,":[146],"ftsW,":[147],"dnaA":[148],"unprocessed":[150],"16S":[151],"rRNA":[152],"transcripts":[153],"not":[155],"changed":[156],"super-infection.":[159],"These":[160],"data":[161],"indicate":[162],"superinfection":[165],"drives":[166],"chlamydia":[167],"into":[168],"a":[169],"viable":[170],"but":[171],"non-cultivable":[172],"state,":[173],"which":[174],"is":[175],"the":[176],"hallmark":[177],"persistence.":[179],"Because":[180],"HSP60-1":[182],"has":[183],"been":[184],"associated":[185],"immunopathology":[187],"vivo,":[189],"results":[191],"also":[192],"suggest":[193],"disease":[195],"severity":[196],"might":[197],"be":[198],"increased":[199],"individuals.":[202]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":10},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}