{"id":"https://openalex.org/W2013960897","doi":"https://doi.org/10.1016/s0020-1693(98)00035-8","title":"Intercalator-linked cisplatin: synthesis and antitumor activity of cis-dichloroplatinum(II) complexes connected to acridine and phenylquinolines by one methylene chain","display_name":"Intercalator-linked cisplatin: synthesis and antitumor activity of cis-dichloroplatinum(II) complexes connected to acridine and phenylquinolines by one methylene chain","publication_year":1998,"publication_date":"1998-09-01","ids":{"openalex":"https://openalex.org/W2013960897","doi":"https://doi.org/10.1016/s0020-1693(98)00035-8","mag":"2013960897"},"language":"en","primary_location":{"id":"doi:10.1016/s0020-1693(98)00035-8","doi":"https://doi.org/10.1016/s0020-1693(98)00035-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0020-1693(98)00035-8","pdf_url":null,"source":{"id":"https://openalex.org/S112227793","display_name":"Inorganica Chimica Acta","issn_l":"0020-1693","issn":["0020-1693","1873-3255"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inorganica Chimica Acta","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068352055","display_name":"Yuji Mikata","orcid":"https://orcid.org/0000-0002-9450-0908","observed_orcids":["https://orcid.org/0000-0002-9450-0908"]},"institutions":[{"id":"https://openalex.org/I98885092","display_name":"Nara Women's University","ror":"https://ror.org/05kzadn81","country_code":"JP","type":"education","lineage":["https://openalex.org/I4405286766","https://openalex.org/I98885092"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuji Mikata","raw_affiliation_strings":["Department of Chemistry, Faculty of Science, Nara Women's University, Nara 630, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Faculty of Science, Nara Women's University, Nara 630, Japan","institution_ids":["https://openalex.org/I98885092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111739405","display_name":"Mika Yokoyama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98885092","display_name":"Nara Women's University","ror":"https://ror.org/05kzadn81","country_code":"JP","type":"education","lineage":["https://openalex.org/I4405286766","https://openalex.org/I98885092"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mika Yokoyama","raw_affiliation_strings":["Department of Chemistry, Faculty of Science, Nara Women's University, Nara 630, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Faculty of Science, Nara Women's University, Nara 630, Japan","institution_ids":["https://openalex.org/I98885092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073260733","display_name":"Kaoru Mogami","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98885092","display_name":"Nara Women's University","ror":"https://ror.org/05kzadn81","country_code":"JP","type":"education","lineage":["https://openalex.org/I4405286766","https://openalex.org/I98885092"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kaoru Mogami","raw_affiliation_strings":["Department of Chemistry, Faculty of Science, Nara Women's University, Nara 630, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Faculty of Science, Nara Women's University, Nara 630, Japan","institution_ids":["https://openalex.org/I98885092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025217672","display_name":"Masako Kato","orcid":"https://orcid.org/0000-0002-6932-9758","observed_orcids":["https://orcid.org/0000-0002-6932-9758"]},"institutions":[{"id":"https://openalex.org/I98885092","display_name":"Nara Women's University","ror":"https://ror.org/05kzadn81","country_code":"JP","type":"education","lineage":["https://openalex.org/I4405286766","https://openalex.org/I98885092"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masako Kato","raw_affiliation_strings":["Department of Chemistry, Faculty of Science, Nara Women's University, Nara 630, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Faculty of Science, Nara Women's University, Nara 630, Japan","institution_ids":["https://openalex.org/I98885092"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110044304","display_name":"Ichiro Okura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114531698","display_name":"Tokyo Institute of Technology","ror":"https://ror.org/0112mx960","country_code":"JP","type":"education","lineage":["https://openalex.org/I114531698","https://openalex.org/I4400009020"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ichiro Okura","raw_affiliation_strings":["Department of Bioengineering, Tokyo Institute of Technology, Nagatsuta, Yokohama 226, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioengineering, Tokyo Institute of Technology, Nagatsuta, Yokohama 226, Japan","institution_ids":["https://openalex.org/I114531698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081305621","display_name":"Makoto Chikira","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I96679780","display_name":"Chuo University","ror":"https://ror.org/03qvqb743","country_code":"JP","type":"education","lineage":["https://openalex.org/I96679780"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Makoto Chikira","raw_affiliation_strings":["Department of Applied Chemistry, Chuo University, Bunkyo-ku, Tokyo 112, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Applied Chemistry, Chuo University, Bunkyo-ku, Tokyo 112, Japan","institution_ids":["https://openalex.org/I96679780"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037580322","display_name":"Shigenobu Yano","orcid":"https://orcid.org/0000-0002-6815-0895","observed_orcids":["https://orcid.org/0000-0002-6815-0895"]},"institutions":[{"id":"https://openalex.org/I98885092","display_name":"Nara Women's University","ror":"https://ror.org/05kzadn81","country_code":"JP","type":"education","lineage":["https://openalex.org/I4405286766","https://openalex.org/I98885092"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Shigenobu Yano","raw_affiliation_strings":["Department of Chemistry, Faculty of Science, Nara Women's University, Nara 630, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Faculty of Science, Nara Women's University, Nara 630, Japan","institution_ids":["https://openalex.org/I98885092"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5037580322"],"corresponding_institution_ids":["https://openalex.org/I98885092"],"apc_list":{"value":3830,"currency":"USD","value_usd":3830},"apc_paid":null,"fwci":0.5552,"has_fulltext":false,"cited_by_count":63,"citation_normalized_percentile":{"value":0.67964586,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"279","issue":"1","first_page":"51","last_page":"57"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10163","display_name":"Metal complexes synthesis and properties","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10163","display_name":"Metal complexes synthesis and properties","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11845","display_name":"Cancer therapeutics and mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10092","display_name":"Organometallic Complex Synthesis and Catalysis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acridine-ligands","display_name":"acridine ligands","score":0.9089999794960022},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.8119999766349792},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.890999972820282},{"id":"https://openalex.org/keywords/dna-intercalation","display_name":"DNA intercalation","score":0.8579999804496765},{"id":"https://openalex.org/keywords/dna-binding-affinity","display_name":"DNA binding affinity","score":0.8690000176429749},{"id":"https://openalex.org/keywords/hela-cells","display_name":"HeLa cells","score":0.8299999833106995},{"id":"https://openalex.org/keywords/p388-leukemia-cells","display_name":"P388 leukemia cells","score":0.8980000019073486},{"id":"https://openalex.org/keywords/crystal-structure","display_name":"crystal structure","score":0.574999988079071}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9353792667388916},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.7564390897750854},{"id":"https://openalex.org/C2776924795","wikidata":"https://www.wikidata.org/wiki/Q342713","display_name":"Acridine","level":2,"score":0.7498398423194885},{"id":"https://openalex.org/C2777366897","wikidata":"https://www.wikidata.org/wiki/Q847482","display_name":"HeLa","level":3,"score":0.7146782279014587},{"id":"https://openalex.org/C2776568683","wikidata":"https://www.wikidata.org/wiki/Q23005640","display_name":"Moiety","level":2,"score":0.6944261193275452},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.6909983158111572},{"id":"https://openalex.org/C2778239845","wikidata":"https://www.wikidata.org/wiki/Q412415","display_name":"Cisplatin","level":3,"score":0.6511514782905579},{"id":"https://openalex.org/C2777454769","wikidata":"https://www.wikidata.org/wiki/Q11172462","display_name":"Methylene","level":2,"score":0.5874457955360413},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.5077632665634155},{"id":"https://openalex.org/C137824038","wikidata":"https://www.wikidata.org/wiki/Q175562","display_name":"Intercalation (chemistry)","level":2,"score":0.4778296947479248},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.18813365697860718},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.17963451147079468},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15448930859565735},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.09990358352661133},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.0},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1016/s0020-1693(98)00035-8","doi":"https://doi.org/10.1016/s0020-1693(98)00035-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0020-1693(98)00035-8","pdf_url":null,"source":{"id":"https://openalex.org/S112227793","display_name":"Inorganica Chimica Acta","issn_l":"0020-1693","issn":["0020-1693","1873-3255"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inorganica Chimica Acta","raw_type":"journal-article"},{"id":"pmh:oai:irdb.nii.ac.jp:00897:0003898476","doi":null,"is_oa":false,"landing_page_url":"http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100435017","pdf_url":null,"source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Inorg. Chim. Acta","raw_type":"journal article"},{"id":"pmh:oai:t2r2.star.titech.ac.jp:00036988","doi":null,"is_oa":false,"landing_page_url":"http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100435017","pdf_url":null,"source":{"id":"https://openalex.org/S4377196385","display_name":"Tokyo Tech Research Repository (Tokyo Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114531698","host_organization_name":"Tokyo Institute of Technology","host_organization_lineage":["https://openalex.org/I114531698"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W625827176","https://openalex.org/W1973856448","https://openalex.org/W1980674013","https://openalex.org/W1986122526","https://openalex.org/W1990158000","https://openalex.org/W2001076027","https://openalex.org/W2004592691","https://openalex.org/W2010710383","https://openalex.org/W2013359296","https://openalex.org/W2014443006","https://openalex.org/W2018466113","https://openalex.org/W2020495161","https://openalex.org/W2059128931","https://openalex.org/W2068763880","https://openalex.org/W2069079191","https://openalex.org/W2071959246","https://openalex.org/W2077266389","https://openalex.org/W2080422533","https://openalex.org/W2082464315","https://openalex.org/W2085822586","https://openalex.org/W2087387065","https://openalex.org/W2093674987","https://openalex.org/W2095856651","https://openalex.org/W2323447129","https://openalex.org/W2418506623"],"related_works":["https://openalex.org/W2068763880","https://openalex.org/W2069079191","https://openalex.org/W2013359296","https://openalex.org/W2017428275","https://openalex.org/W2016914067","https://openalex.org/W2067117822","https://openalex.org/W2089775431","https://openalex.org/W1968670662","https://openalex.org/W2145913444","https://openalex.org/W2045318320"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}