{"id":"https://openalex.org/W2013805669","doi":"https://doi.org/10.2174/2210315511303020005","title":"Marine Collagen as a Source of Bioactive Molecules: A Review","display_name":"Marine Collagen as a Source of Bioactive Molecules: A Review","publication_year":2013,"publication_date":"2013-05-01","ids":{"openalex":"https://openalex.org/W2013805669","doi":"https://doi.org/10.2174/2210315511303020005","mag":"2013805669"},"language":"en","primary_location":{"id":"doi:10.2174/2210315511303020005","doi":"https://doi.org/10.2174/2210315511303020005","is_oa":false,"landing_page_url":"https://doi.org/10.2174/2210315511303020005","pdf_url":null,"source":{"id":"https://openalex.org/S4210177943","display_name":"The Natural Products Journal","issn_l":"2210-3155","issn":["2210-3155","2210-3163"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","poland-20","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Natural Products Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10261/88241","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036295948","display_name":"Ail\u00e9n Alem\u00e1n","orcid":"https://orcid.org/0000-0002-9209-1231","observed_orcids":["https://orcid.org/0000-0002-9209-1231"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ailen Aleman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5028366500","display_name":"\u00d3scar Mart\u00ednez\u2010\u00c1lvarez","orcid":"https://orcid.org/0000-0002-9643-1619","observed_orcids":["https://orcid.org/0000-0002-9643-1619"]},"institutions":[{"id":"https://openalex.org/I134820265","display_name":"Consejo Superior de Investigaciones Cient\u00edficas","ror":"https://ror.org/02gfc7t72","country_code":"ES","type":"government","lineage":["https://openalex.org/I134820265"]},{"id":"https://openalex.org/I4210131621","display_name":"Instituto de Ciencia y Tecnolog\u00eda de Alimentos y Nutrici\u00f3n","ror":"https://ror.org/045yy3r21","country_code":"ES","type":"facility","lineage":["https://openalex.org/I134820265","https://openalex.org/I4210131621"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Oscar Martinez-Alvarez","raw_affiliation_strings":["Institute of Food Science, Technology and Nutrition (ICTAN-CSIC)#, Ciudad Universitaria, 28040 Madrid, Spain.,Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Food Science, Technology and Nutrition (ICTAN-CSIC)#, Ciudad Universitaria, 28040 Madrid, Spain.,Spain","institution_ids":["https://openalex.org/I134820265","https://openalex.org/I4210131621"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5028366500"],"corresponding_institution_ids":["https://openalex.org/I134820265","https://openalex.org/I4210131621"],"apc_list":null,"apc_paid":null,"fwci":1.1305,"has_fulltext":false,"cited_by_count":50,"citation_normalized_percentile":{"value":0.78160219,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"3","issue":"2","first_page":"105","last_page":"114"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11561","display_name":"Protein Hydrolysis and Bioactive Peptides","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11561","display_name":"Protein Hydrolysis and Bioactive Peptides","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12085","display_name":"Collagen: Extraction and Characterization","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14010","display_name":"Food Industry and Aquatic Biology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/marine-collagen","display_name":"marine collagen","score":0.9940000176429749},{"id":"https://openalex.org/keywords/fish-by-products","display_name":"fish by-products","score":0.746999979019165},{"id":"https://openalex.org/keywords/bioactive-peptides","display_name":"bioactive peptides","score":0.8489999771118164},{"id":"https://openalex.org/keywords/enzymatic-hydrolysis","display_name":"enzymatic hydrolysis","score":0.9449999928474426},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.8240000009536743},{"id":"https://openalex.org/keywords/antihypertensive-effect","display_name":"antihypertensive effect","score":0.9819999933242798},{"id":"https://openalex.org/keywords/antimicrobial-activity","display_name":"antimicrobial activity","score":0.8960000276565552},{"id":"https://openalex.org/keywords/chondroprotection","display_name":"chondroprotection","score":0.9610000252723694},{"id":"https://openalex.org/keywords/bone-formation","display_name":"bone formation","score":0.953000009059906},{"id":"https://openalex.org/keywords/satiety","display_name":"satiety","score":0.8460000157356262},{"id":"https://openalex.org/keywords/opioid-peptides","display_name":"opioid peptides","score":0.8849999904632568},{"id":"https://openalex.org/keywords/protein-digestibility","display_name":"protein digestibility","score":0.5299999713897705},{"id":"https://openalex.org/keywords/nutraceuticals","display_name":"nutraceuticals","score":0.7820000052452087},{"id":"https://openalex.org/keywords/health-promoting-foods","display_name":"health-promoting foods","score":0.6610000133514404}],"concepts":[{"id":"https://openalex.org/C2778823387","wikidata":"https://www.wikidata.org/wiki/Q179254","display_name":"Gelatin","level":2,"score":0.8332433700561523},{"id":"https://openalex.org/C17857428","wikidata":"https://www.wikidata.org/wiki/Q533025","display_name":"Nutraceutical","level":2,"score":0.7583093047142029},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7518746852874756},{"id":"https://openalex.org/C28800991","wikidata":"https://www.wikidata.org/wiki/Q15634405","display_name":"Hydrolysate","level":3,"score":0.6650243997573853},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.5898084044456482},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.5772209763526917},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.5169500708580017},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.45496708154678345},{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.439699649810791},{"id":"https://openalex.org/C3018122547","wikidata":"https://www.wikidata.org/wiki/Q5690813","display_name":"Health benefits","level":2,"score":0.43946659564971924},{"id":"https://openalex.org/C94412978","wikidata":"https://www.wikidata.org/wiki/Q103135","display_name":"Hydrolysis","level":2,"score":0.36758261919021606},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14557239413261414},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.13506844639778137},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.10869660973548889},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.09696558117866516},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.2174/2210315511303020005","doi":"https://doi.org/10.2174/2210315511303020005","is_oa":false,"landing_page_url":"https://doi.org/10.2174/2210315511303020005","pdf_url":null,"source":{"id":"https://openalex.org/S4210177943","display_name":"The Natural Products Journal","issn_l":"2210-3155","issn":["2210-3155","2210-3163"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","poland-20","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Natural Products Journal","raw_type":"journal-article"},{"id":"pmh:oai:digital.csic.es:10261/88241","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10261/88241","pdf_url":null,"source":{"id":"https://openalex.org/S4306400616","display_name":"DIGITAL.CSIC (Spanish National Research Council (CSIC))","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I134820265","host_organization_name":"Consejo Superior de Investigaciones Cient\u00edficas","host_organization_lineage":["https://openalex.org/I134820265"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Art\u00edculo"}],"best_oa_location":{"id":"pmh:oai:digital.csic.es:10261/88241","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10261/88241","pdf_url":null,"source":{"id":"https://openalex.org/S4306400616","display_name":"DIGITAL.CSIC (Spanish National Research Council (CSIC))","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I134820265","host_organization_name":"Consejo Superior de Investigaciones Cient\u00edficas","host_organization_lineage":["https://openalex.org/I134820265"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Art\u00edculo"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/14","display_name":"Life below water","score":0.6018000245094299},{"id":"https://metadata.un.org/sdg/12","display_name":"Responsible consumption and production","score":0.5925999879837036}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":111,"referenced_works":["https://openalex.org/W90548619","https://openalex.org/W159694880","https://openalex.org/W1504680783","https://openalex.org/W1526274871","https://openalex.org/W1611092567","https://openalex.org/W1965946877","https://openalex.org/W1969257238","https://openalex.org/W1973716078","https://openalex.org/W1975651686","https://openalex.org/W1975754383","https://openalex.org/W1977339930","https://openalex.org/W1977390994","https://openalex.org/W1978389916","https://openalex.org/W1978777608","https://openalex.org/W1979416106","https://openalex.org/W1979901694","https://openalex.org/W1981716514","https://openalex.org/W1986568715","https://openalex.org/W1986767591","https://openalex.org/W1988706339","https://openalex.org/W1989573274","https://openalex.org/W1989998611","https://openalex.org/W1990919233","https://openalex.org/W1991255625","https://openalex.org/W1991776232","https://openalex.org/W1992058473","https://openalex.org/W1993737048","https://openalex.org/W1993920060","https://openalex.org/W1994235482","https://openalex.org/W1995475849","https://openalex.org/W1997226607","https://openalex.org/W1997513241","https://openalex.org/W2001483688","https://openalex.org/W2007459036","https://openalex.org/W2007482003","https://openalex.org/W2013240662","https://openalex.org/W2013951601","https://openalex.org/W2014177059","https://openalex.org/W2019275100","https://openalex.org/W2019544986","https://openalex.org/W2020395259","https://openalex.org/W2020720616","https://openalex.org/W2021155760","https://openalex.org/W2021261187","https://openalex.org/W2021870280","https://openalex.org/W2024074948","https://openalex.org/W2025024262","https://openalex.org/W2025547158","https://openalex.org/W2026564439","https://openalex.org/W2033628180","https://openalex.org/W2040524345","https://openalex.org/W2040727433","https://openalex.org/W2041907785","https://openalex.org/W2042004213","https://openalex.org/W2044720566","https://openalex.org/W2044984549","https://openalex.org/W2045743453","https://openalex.org/W2045755637","https://openalex.org/W2053870372","https://openalex.org/W2054276115","https://openalex.org/W2054602599","https://openalex.org/W2057908978","https://openalex.org/W2058523784","https://openalex.org/W2059218697","https://openalex.org/W2060388191","https://openalex.org/W2061129149","https://openalex.org/W2063633164","https://openalex.org/W2064627397","https://openalex.org/W2066067895","https://openalex.org/W2066264822","https://openalex.org/W2066440208","https://openalex.org/W2067576004","https://openalex.org/W2069732215","https://openalex.org/W2073110854","https://openalex.org/W2073620711","https://openalex.org/W2074419725","https://openalex.org/W2079906726","https://openalex.org/W2080456946","https://openalex.org/W2082314218","https://openalex.org/W2084653777","https://openalex.org/W2085599090","https://openalex.org/W2085911570","https://openalex.org/W2086058746","https://openalex.org/W2094385925","https://openalex.org/W2105146822","https://openalex.org/W2105158048","https://openalex.org/W2107501146","https://openalex.org/W2111142477","https://openalex.org/W2111729861","https://openalex.org/W2114837974","https://openalex.org/W2124552229","https://openalex.org/W2126069059","https://openalex.org/W2126080411","https://openalex.org/W2130625170","https://openalex.org/W2130974803","https://openalex.org/W2135254765","https://openalex.org/W2138628715","https://openalex.org/W2149689059","https://openalex.org/W2155500010","https://openalex.org/W2157237136","https://openalex.org/W2159105810","https://openalex.org/W2162014018","https://openalex.org/W2164618556","https://openalex.org/W2169650544","https://openalex.org/W2169776281","https://openalex.org/W2294118135","https://openalex.org/W2327880879","https://openalex.org/W2417986221","https://openalex.org/W2419634710","https://openalex.org/W2422999076","https://openalex.org/W2889017119"],"related_works":["https://openalex.org/W3038249778","https://openalex.org/W3090014117","https://openalex.org/W4408999981","https://openalex.org/W4376278310","https://openalex.org/W2254444843","https://openalex.org/W3017263212","https://openalex.org/W7076809143","https://openalex.org/W2947262981","https://openalex.org/W4398238603","https://openalex.org/W4401210890"],"abstract_inverted_index":{"Skins,":[0],"scales":[1],"and":[2,21,43,78,94],"bones":[3],"are":[4,14,22,33],"the":[5,9],"major":[6],"by-products":[7,13,32],"of":[8,37,67,91,105],"fish-processing":[10],"industry.":[11],"These":[12],"not":[15],"regarded":[16],"as":[17],"ordinary":[18],"saleable":[19],"products":[20],"usually":[23],"discarded":[24],"causing":[25],"a":[26,34],"heavy":[27],"environmental":[28],"impact.":[29],"However,":[30],"marine":[31],"good":[35],"source":[36],"collagen":[38],"that":[39],"could":[40],"be":[41],"extracted":[42],"further":[44],"enzymatically":[45],"hydrolyzed":[46],"to":[47,74,98],"liberate":[48],"interesting":[49,56,81],"bioactive":[50,89],"peptides.":[51],"Collagen-derived":[52],"peptides":[53],"may":[54],"exhibit":[55],"antioxidant":[57],"activity,":[58,61],"potent":[59],"antihypertensive":[60],"antimicrobial":[62],"activity":[63],"against":[64],"different":[65],"strains":[66],"bacteria,":[68],"protective":[69],"effect":[70],"on":[71],"cartilage,":[72],"capacity":[73],"stimulate":[75],"bone":[76],"formation,":[77],"also":[79,95],"other":[80],"activities":[82],"(e.g.,":[83],"satiety,":[84],"calciotropic,":[85],"or":[86],"opioid).":[87],"The":[88],"properties":[90],"collagen-derived":[92],"peptides,":[93,111],"their":[96],"resistance":[97],"protein":[99],"digestion,":[100],"make":[101],"them":[102],"potential":[103],"ingredients":[104],"health":[106],"promoting":[107],"foods.":[108],"Keywords:":[109],"Bioactive":[110],"by-products,":[112],"collagen,":[113],"fish,":[114],"gelatin,":[115],"hydrolysates,":[116],"nutraceuticals.":[117]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}