{"id":"https://openalex.org/W2013787313","doi":"https://doi.org/10.1038/cgt.2010.16","title":"Targeting MMP-9, uPAR, and cathepsin B inhibits invasion, migration and activates apoptosis in prostate cancer cells","display_name":"Targeting MMP-9, uPAR, and cathepsin B inhibits invasion, migration and activates apoptosis in prostate cancer cells","publication_year":2010,"publication_date":"2010-05-07","ids":{"openalex":"https://openalex.org/W2013787313","doi":"https://doi.org/10.1038/cgt.2010.16","mag":"2013787313","pmid":"https://pubmed.ncbi.nlm.nih.gov/20448670","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2919627"},"language":"en","primary_location":{"id":"doi:10.1038/cgt.2010.16","doi":"https://doi.org/10.1038/cgt.2010.16","is_oa":false,"landing_page_url":"https://doi.org/10.1038/cgt.2010.16","pdf_url":null,"source":{"id":"https://openalex.org/S157451995","display_name":"Cancer Gene Therapy","issn_l":"0929-1903","issn":["0929-1903","1476-5500"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","medline","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Gene Therapy","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2919627","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010004856","display_name":"Arun Kumar Nalla","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130227","display_name":"Peoria campus of the University of Illinois System","ror":"https://ror.org/02qrdc062","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238","https://openalex.org/I4210130227"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A K Nalla","raw_affiliation_strings":["Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine, Peoria, IL 61605, USA","Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine, Peoria, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine, Peoria, IL 61605, USA","institution_ids":["https://openalex.org/I4210130227"]},{"raw_affiliation_string":"Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine, Peoria, IL, USA","institution_ids":["https://openalex.org/I4210130227"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010176744","display_name":"Bharathi Gorantla","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130227","display_name":"Peoria campus of the University of Illinois System","ror":"https://ror.org/02qrdc062","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238","https://openalex.org/I4210130227"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B Gorantla","raw_affiliation_strings":["Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine, Peoria, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine, Peoria, IL, USA","institution_ids":["https://openalex.org/I4210130227"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110995347","display_name":"Christopher S. Gondi","orcid":"https://orcid.org/0000-0002-3036-9920","observed_orcids":["https://orcid.org/0000-0002-3036-9920"]},"institutions":[{"id":"https://openalex.org/I4210130227","display_name":"Peoria campus of the University of Illinois System","ror":"https://ror.org/02qrdc062","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238","https://openalex.org/I4210130227"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C S Gondi","raw_affiliation_strings":["Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine, Peoria, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine, Peoria, IL, USA","institution_ids":["https://openalex.org/I4210130227"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056097889","display_name":"Sajani S. Lakka","orcid":"https://orcid.org/0000-0002-8786-5626","observed_orcids":["https://orcid.org/0000-0002-8786-5626"]},"institutions":[{"id":"https://openalex.org/I4210130227","display_name":"Peoria campus of the University of Illinois System","ror":"https://ror.org/02qrdc062","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238","https://openalex.org/I4210130227"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S S Lakka","raw_affiliation_strings":["Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine, Peoria, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine, Peoria, IL, USA","institution_ids":["https://openalex.org/I4210130227"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108423931","display_name":"Jagadeesh Sridhara Rao","orcid":"https://orcid.org/0000-0002-5476-8512","observed_orcids":["https://orcid.org/0000-0002-5476-8512"]},"institutions":[{"id":"https://openalex.org/I4210130227","display_name":"Peoria campus of the University of Illinois System","ror":"https://ror.org/02qrdc062","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238","https://openalex.org/I4210130227"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"J S Rao","raw_affiliation_strings":["Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine, Peoria, IL, USA","Department of Neurosurgery, University of Illinois College of Medicine, Peoria, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine, Peoria, IL, USA","institution_ids":["https://openalex.org/I4210130227"]},{"raw_affiliation_string":"Department of Neurosurgery, University of Illinois College of Medicine, Peoria, IL, USA","institution_ids":["https://openalex.org/I4210130227"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5108423931"],"corresponding_institution_ids":["https://openalex.org/I4210130227"],"apc_list":{"value":4990,"currency":"USD","value_usd":4990},"apc_paid":null,"fwci":3.321,"has_fulltext":false,"cited_by_count":125,"citation_normalized_percentile":{"value":0.92320723,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"17","issue":"9","first_page":"599","last_page":"613"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.008200000040233135,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13437","display_name":"Mechanisms of cancer metastasis","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.9990000128746033},{"id":"https://openalex.org/keywords/mmp-9","display_name":"MMP-9","score":0.9629999995231628},{"id":"https://openalex.org/keywords/urokinase-type-plasminogen-activator-receptor","display_name":"urokinase-type plasminogen activator receptor","score":0.9829999804496765},{"id":"https://openalex.org/keywords/cathepsin-b","display_name":"cathepsin B","score":1.0},{"id":"https://openalex.org/keywords/sirna-knockdown","display_name":"siRNA knockdown","score":0.8510000109672546},{"id":"https://openalex.org/keywords/tumor-invasion","display_name":"tumor invasion","score":0.8450000286102295},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.9629999995231628},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9459999799728394},{"id":"https://openalex.org/keywords/fas-mediated-apoptosis","display_name":"Fas-mediated apoptosis","score":0.6570000052452087},{"id":"https://openalex.org/keywords/caspase-8","display_name":"caspase-8","score":0.9629999995231628},{"id":"https://openalex.org/keywords/caspase-7","display_name":"caspase-7","score":0.9940000176429749},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.953000009059906},{"id":"https://openalex.org/keywords/tumor-growth-inhibition","display_name":"tumor growth inhibition","score":0.6850000023841858},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.9010000228881836}],"concepts":[{"id":"https://openalex.org/C56219504","wikidata":"https://www.wikidata.org/wiki/Q7900869","display_name":"Urokinase receptor","level":3,"score":0.8573418855667114},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.773967981338501},{"id":"https://openalex.org/C2776438761","wikidata":"https://www.wikidata.org/wiki/Q5206280","display_name":"DU145","level":5,"score":0.7638803124427795},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.7425110340118408},{"id":"https://openalex.org/C155878803","wikidata":"https://www.wikidata.org/wiki/Q5205755","display_name":"DNA laddering","level":5,"score":0.6488441228866577},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.5666844248771667},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.5362687706947327},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.4791569113731384},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4769138991832733},{"id":"https://openalex.org/C2778608917","wikidata":"https://www.wikidata.org/wiki/Q6787805","display_name":"Matrigel","level":3,"score":0.46444442868232727},{"id":"https://openalex.org/C28021979","wikidata":"https://www.wikidata.org/wiki/Q14911946","display_name":"Cathepsin B","level":3,"score":0.45606696605682373},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.44830504059791565},{"id":"https://openalex.org/C2775975398","wikidata":"https://www.wikidata.org/wiki/Q906904","display_name":"Survivin","level":3,"score":0.42146021127700806},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.39267998933792114},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3534347414970398},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32315999269485474},{"id":"https://openalex.org/C2779679481","wikidata":"https://www.wikidata.org/wiki/Q13581432","display_name":"Plasminogen activator","level":2,"score":0.2670629024505615},{"id":"https://openalex.org/C2779723316","wikidata":"https://www.wikidata.org/wiki/Q6459234","display_name":"LNCaP","level":4,"score":0.26230597496032715},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.2074223756790161},{"id":"https://openalex.org/C43759708","wikidata":"https://www.wikidata.org/wiki/Q3749256","display_name":"DNA fragmentation","level":4,"score":0.2002256214618683},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1619509756565094},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002401","descriptor_name":"Cathepsin B","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002401","descriptor_name":"Cathepsin B","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008819","descriptor_name":"Mice, Nude","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020780","descriptor_name":"Matrix Metalloproteinase 9","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020780","descriptor_name":"Matrix Metalloproteinase 9","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D023041","descriptor_name":"Xenograft Model Antitumor Assays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D034741","descriptor_name":"RNA, Small Interfering","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055293","descriptor_name":"Receptors, Urokinase Plasminogen Activator","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D055293","descriptor_name":"Receptors, Urokinase Plasminogen Activator","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1038/cgt.2010.16","doi":"https://doi.org/10.1038/cgt.2010.16","is_oa":false,"landing_page_url":"https://doi.org/10.1038/cgt.2010.16","pdf_url":null,"source":{"id":"https://openalex.org/S157451995","display_name":"Cancer Gene Therapy","issn_l":"0929-1903","issn":["0929-1903","1476-5500"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","medline","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Gene Therapy","raw_type":"journal-article"},{"id":"pmid:20448670","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20448670","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer gene therapy","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2169664","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2919627","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2919627","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2919627","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Cancer Gene Ther","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2169664","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2919627","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.8799999952316284,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1320390427","display_name":null,"funder_award_id":"CA116708","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4366939855","display_name":null,"funder_award_id":"CA-75557","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4633402684","display_name":"Role of uPA and uPAR in Human Glioma Invasiveness","funder_award_id":"R01CA075557","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G4664707087","display_name":"Inhibition of matrix proteases to sensitize medulloblastoma cells to radiation","funder_award_id":"R01CA138409","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6548941339","display_name":null,"funder_award_id":"CA138409","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G75321199","display_name":"Cath B and uPAR si RNA constructs regressed glioma growth","funder_award_id":"R01CA116708","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":64,"referenced_works":["https://openalex.org/W90697117","https://openalex.org/W1536849363","https://openalex.org/W1574172480","https://openalex.org/W1585336990","https://openalex.org/W1598733586","https://openalex.org/W1668309971","https://openalex.org/W1743523754","https://openalex.org/W1954041220","https://openalex.org/W1963849020","https://openalex.org/W1966007931","https://openalex.org/W1968328677","https://openalex.org/W1971944129","https://openalex.org/W1975577875","https://openalex.org/W1976692354","https://openalex.org/W1984060059","https://openalex.org/W1986308149","https://openalex.org/W1986523660","https://openalex.org/W1992885568","https://openalex.org/W1994567037","https://openalex.org/W1999251467","https://openalex.org/W2003170155","https://openalex.org/W2003500892","https://openalex.org/W2013468201","https://openalex.org/W2021736277","https://openalex.org/W2027275036","https://openalex.org/W2027341857","https://openalex.org/W2035027892","https://openalex.org/W2039918907","https://openalex.org/W2040027552","https://openalex.org/W2042555223","https://openalex.org/W2042676891","https://openalex.org/W2043103956","https://openalex.org/W2046193286","https://openalex.org/W2050608015","https://openalex.org/W2057739013","https://openalex.org/W2061497413","https://openalex.org/W2065716393","https://openalex.org/W2065791048","https://openalex.org/W2066232941","https://openalex.org/W2072669480","https://openalex.org/W2074894180","https://openalex.org/W2080709087","https://openalex.org/W2084536649","https://openalex.org/W2085351616","https://openalex.org/W2087614633","https://openalex.org/W2088238268","https://openalex.org/W2090985686","https://openalex.org/W2092482705","https://openalex.org/W2092565468","https://openalex.org/W2093750293","https://openalex.org/W2097803870","https://openalex.org/W2100131346","https://openalex.org/W2108725202","https://openalex.org/W2123521794","https://openalex.org/W2124235176","https://openalex.org/W2126224980","https://openalex.org/W2127031670","https://openalex.org/W2136978811","https://openalex.org/W2142575602","https://openalex.org/W2143936339","https://openalex.org/W2151878529","https://openalex.org/W2156721214","https://openalex.org/W2159618490","https://openalex.org/W3146308990"],"related_works":["https://openalex.org/W1705608888","https://openalex.org/W3132279377","https://openalex.org/W1989856014","https://openalex.org/W2073198418","https://openalex.org/W1969852115","https://openalex.org/W2110736693","https://openalex.org/W2109301975","https://openalex.org/W2027315940","https://openalex.org/W2148101051","https://openalex.org/W3150946094"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":15},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":8}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}