{"id":"https://openalex.org/W2013752079","doi":"https://doi.org/10.1097/mop.0b013e328336ebb0","title":"Risk factors for progression of chronic kidney disease","display_name":"Risk factors for progression of chronic kidney disease","publication_year":2010,"publication_date":"2010-03-17","ids":{"openalex":"https://openalex.org/W2013752079","doi":"https://doi.org/10.1097/mop.0b013e328336ebb0","mag":"2013752079","pmid":"https://pubmed.ncbi.nlm.nih.gov/20090523","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2948868"},"language":"en","primary_location":{"id":"doi:10.1097/mop.0b013e328336ebb0","doi":"https://doi.org/10.1097/mop.0b013e328336ebb0","is_oa":false,"landing_page_url":"https://doi.org/10.1097/mop.0b013e328336ebb0","pdf_url":null,"source":{"id":"https://openalex.org/S204673346","display_name":"Current Opinion in Pediatrics","issn_l":"1040-8703","issn":["1040-8703","1080-8116","1531-698X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Pediatrics","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2948868","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062164804","display_name":"Amy Otten Staples","orcid":"https://orcid.org/0000-0002-6887-3065","observed_orcids":["https://orcid.org/0000-0002-6887-3065"]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]},{"id":"https://openalex.org/I4210103574","display_name":"UNM Children's Hospital","ror":"https://ror.org/01aq2mh35","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I169521973","https://openalex.org/I4210103574"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amy Staples","raw_affiliation_strings":["Division of Pediatric Nephrology, Department of Pediatrics, University of New Mexico, Children's Hospital, Albuquerque, New Mexico, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pediatric Nephrology, Department of Pediatrics, University of New Mexico, Children's Hospital, Albuquerque, New Mexico, USA","institution_ids":["https://openalex.org/I169521973","https://openalex.org/I4210103574"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113609714","display_name":"Craig Stephen Wong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]},{"id":"https://openalex.org/I4210103574","display_name":"UNM Children's Hospital","ror":"https://ror.org/01aq2mh35","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I169521973","https://openalex.org/I4210103574"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Craig Wong","raw_affiliation_strings":["Division of Pediatric Nephrology, Department of Pediatrics, University of New Mexico, Children's Hospital, Albuquerque, New Mexico, USA","to Craig Wong, MD, MPH, Division of Pediatric Nephrology, Department of Pediatrics, MSC10-5590, 1 University of New Mexico, Albuquerque, NM 87131-0001, USA E-mail: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pediatric Nephrology, Department of Pediatrics, University of New Mexico, Children's Hospital, Albuquerque, New Mexico, USA","institution_ids":["https://openalex.org/I169521973","https://openalex.org/I4210103574"]},{"raw_affiliation_string":"to Craig Wong, MD, MPH, Division of Pediatric Nephrology, Department of Pediatrics, MSC10-5590, 1 University of New Mexico, Albuquerque, NM 87131-0001, USA E-mail: [email\u00a0protected]","institution_ids":["https://openalex.org/I169521973"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5113609714"],"corresponding_institution_ids":["https://openalex.org/I169521973","https://openalex.org/I4210103574"],"apc_list":null,"apc_paid":null,"fwci":0.4946,"has_fulltext":false,"cited_by_count":74,"citation_normalized_percentile":{"value":0.42086957,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"22","issue":"2","first_page":"161","last_page":"169"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11174","display_name":"Pediatric Urology and Nephrology Studies","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-kidney-disease-progression","display_name":"chronic kidney disease progression","score":0.9309999942779541},{"id":"https://openalex.org/keywords/pediatric-chronic-kidney-disease","display_name":"pediatric chronic kidney disease","score":0.9800000190734863},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.9700000286102295},{"id":"https://openalex.org/keywords/glomerular-filtration-rate","display_name":"glomerular filtration rate","score":0.9570000171661377},{"id":"https://openalex.org/keywords/proteinuria","display_name":"proteinuria","score":0.9520000219345093},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.9929999709129333},{"id":"https://openalex.org/keywords/anemia","display_name":"anemia","score":0.9769999980926514},{"id":"https://openalex.org/keywords/genetic-risk-factors","display_name":"genetic risk factors","score":0.9129999876022339},{"id":"https://openalex.org/keywords/genome-wide-association-study","display_name":"genome-wide association study","score":0.9269999861717224}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8993641138076782},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.66603022813797},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.44594091176986694},{"id":"https://openalex.org/C2987552334","wikidata":"https://www.wikidata.org/wiki/Q383126","display_name":"Chronic disease","level":2,"score":0.4108966290950775},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36154747009277344},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.34790873527526855},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005919","descriptor_name":"Glomerular Filtration Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1097/mop.0b013e328336ebb0","doi":"https://doi.org/10.1097/mop.0b013e328336ebb0","is_oa":false,"landing_page_url":"https://doi.org/10.1097/mop.0b013e328336ebb0","pdf_url":null,"source":{"id":"https://openalex.org/S204673346","display_name":"Current Opinion in Pediatrics","issn_l":"1040-8703","issn":["1040-8703","1080-8116","1531-698X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Pediatrics","raw_type":"journal-article"},{"id":"pmid:20090523","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20090523","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current opinion in pediatrics","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2948868","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2948868","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Curr Opin Pediatr","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2948868","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2948868","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Curr Opin Pediatr","raw_type":"Text"},"sustainable_development_goals":[{"score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6083425144","display_name":"University of New Mexico - General Clinical Research Center","funder_award_id":"M01RR000997","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G6236412809","display_name":null,"funder_award_id":"L40 DK065820","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G9000903932","display_name":"Chronic Kidney Disease in Children (CKiD V)","funder_award_id":"U01DK066143","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":79,"referenced_works":["https://openalex.org/W1516392410","https://openalex.org/W1967490910","https://openalex.org/W1979109438","https://openalex.org/W1983891915","https://openalex.org/W1988075826","https://openalex.org/W1991595901","https://openalex.org/W1992395009","https://openalex.org/W1995758506","https://openalex.org/W2001591759","https://openalex.org/W2004437896","https://openalex.org/W2012766272","https://openalex.org/W2014855569","https://openalex.org/W2015336570","https://openalex.org/W2018224519","https://openalex.org/W2024817920","https://openalex.org/W2027710937","https://openalex.org/W2031005241","https://openalex.org/W2031026506","https://openalex.org/W2040029744","https://openalex.org/W2044335718","https://openalex.org/W2048596181","https://openalex.org/W2049701327","https://openalex.org/W2054225562","https://openalex.org/W2058286579","https://openalex.org/W2067988311","https://openalex.org/W2068131038","https://openalex.org/W2069976662","https://openalex.org/W2070237364","https://openalex.org/W2071439002","https://openalex.org/W2074921359","https://openalex.org/W2075391935","https://openalex.org/W2075785968","https://openalex.org/W2082818360","https://openalex.org/W2085182596","https://openalex.org/W2087580623","https://openalex.org/W2088085043","https://openalex.org/W2091820416","https://openalex.org/W2092271853","https://openalex.org/W2096587435","https://openalex.org/W2098011461","https://openalex.org/W2100619505","https://openalex.org/W2103517401","https://openalex.org/W2105193808","https://openalex.org/W2105885585","https://openalex.org/W2107837933","https://openalex.org/W2108287758","https://openalex.org/W2108629029","https://openalex.org/W2108807575","https://openalex.org/W2110453024","https://openalex.org/W2112913890","https://openalex.org/W2113547986","https://openalex.org/W2115586500","https://openalex.org/W2116527412","https://openalex.org/W2121965895","https://openalex.org/W2122730408","https://openalex.org/W2122855609","https://openalex.org/W2125338849","https://openalex.org/W2127147333","https://openalex.org/W2133416234","https://openalex.org/W2134487085","https://openalex.org/W2136871445","https://openalex.org/W2139833466","https://openalex.org/W2143313344","https://openalex.org/W2143954917","https://openalex.org/W2153668464","https://openalex.org/W2155194084","https://openalex.org/W2160180886","https://openalex.org/W2161840616","https://openalex.org/W2167293685","https://openalex.org/W2169485199","https://openalex.org/W2189612961","https://openalex.org/W2270669221","https://openalex.org/W2322416634","https://openalex.org/W2413389682","https://openalex.org/W2487377689","https://openalex.org/W3156148333","https://openalex.org/W4241705079","https://openalex.org/W4301662187","https://openalex.org/W4302048212"],"related_works":["https://openalex.org/W4322758595","https://openalex.org/W2133994210","https://openalex.org/W3003631205","https://openalex.org/W2944129302","https://openalex.org/W3179636978","https://openalex.org/W3149570961","https://openalex.org/W2760946315","https://openalex.org/W1775290330","https://openalex.org/W4414341300","https://openalex.org/W4384470720"],"abstract_inverted_index":{"PURPOSE":[0],"OF":[1],"REVIEW:":[2],"The":[3],"present":[4],"review":[5],"provides":[6],"an":[7],"overview":[8],"of":[9,41,50,67,80,87,139,155,160],"the":[10,21,27,48,110,153,161],"identified":[11,122,182],"risk":[12,68,107,130,163,180],"factors":[13,69,108,131,164,181],"for":[14,63,70,94,132,165,177],"chronic":[15],"kidney":[16,43,81],"disease":[17],"(CKD)":[18],"progression":[19,72,167],"emphasizing":[20],"pediatric":[22,76],"population.":[23],"RECENT":[24],"FINDINGS:":[25],"Over":[26],"past":[28],"10":[29],"years,":[30],"there":[31],"have":[32,121,126,146],"been":[33],"significant":[34],"changes":[35],"to":[36,148,152],"our":[37],"understanding":[38],"and":[39,54,65,89,104,116],"study":[40,115],"preterminal":[42],"failure.":[44],"Recent":[45],"refinements":[46,151],"in":[47,73,99],"measurement":[49],"glomerular":[51,55,100],"filtration":[52,56,101],"rate":[53,57],"estimating":[58],"equations":[59],"are":[60,91],"important":[61,150,176],"tools":[62],"identification":[64],"association":[66,119],"CKD":[71,133,142,156],"children.":[74],"In":[75],"CKD,":[77],"lower":[78],"level":[79],"function":[82],"at":[83],"presentation,":[84],"higher":[85],"levels":[86],"proteinuria,":[88],"hypertension":[90],"known":[92],"markers":[93],"a":[95],"more":[96],"rapid":[97],"decline":[98],"rate.":[102],"Anemia":[103],"other":[105],"reported":[106],"from":[109],"pregenomic":[111],"era":[112],"require":[113],"further":[114],"validation.":[117],"Genome-wide":[118],"studies":[120,138],"genetic":[123,129],"loci":[124],"that":[125],"provided":[127],"novel":[128,179],"progression.":[134,157],"SUMMARY:":[135],"With":[136],"cohort":[137],"children":[140],"with":[141],"becoming":[143],"mature,":[144],"they":[145],"started":[147],"yield":[149],"assessment":[154],"Although":[158],"many":[159],"traditional":[162],"renal":[166],"will":[168,174],"certainly":[169],"be":[170,175],"assessed,":[171],"such":[172],"cohorts":[173],"evaluating":[178],"by":[183],"genome-wide":[184],"studies.":[185]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}