{"id":"https://openalex.org/W2013729607","doi":"https://doi.org/10.1016/s0140-6736(77)90116-7","title":"RADIOTHERAPY AND HYPERBARIC OXYGEN IN HEAD AND NECK CANCER","display_name":"RADIOTHERAPY AND HYPERBARIC OXYGEN IN HEAD AND NECK CANCER","publication_year":1977,"publication_date":"1977-07-01","ids":{"openalex":"https://openalex.org/W2013729607","doi":"https://doi.org/10.1016/s0140-6736(77)90116-7","mag":"2013729607","pmid":"https://pubmed.ncbi.nlm.nih.gov/69191"},"language":"en","primary_location":{"id":"doi:10.1016/s0140-6736(77)90116-7","doi":"https://doi.org/10.1016/s0140-6736(77)90116-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0140-6736(77)90116-7","pdf_url":null,"source":{"id":"https://openalex.org/S49861241","display_name":"The Lancet","issn_l":"0099-5355","issn":["0099-5355","0140-6736","1474-547X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111123869","display_name":"J.M. Henk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210150388","display_name":"Velindre Cancer Centre","ror":"https://ror.org/049sr1d03","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799279586","https://openalex.org/I4210150388"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J.M. Henk","raw_affiliation_strings":["South Wales Radiotherapy and Oncology Service, Velindre Hospital, Cardiff, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"South Wales Radiotherapy and Oncology Service, Velindre Hospital, Cardiff, United Kingdom","institution_ids":["https://openalex.org/I4210150388"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072443183","display_name":"P. B. Kunkler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210150388","display_name":"Velindre Cancer Centre","ror":"https://ror.org/049sr1d03","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799279586","https://openalex.org/I4210150388"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"P.B. Kunkler","raw_affiliation_strings":["South Wales Radiotherapy and Oncology Service, Velindre Hospital, Cardiff, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"South Wales Radiotherapy and Oncology Service, Velindre Hospital, Cardiff, United Kingdom","institution_ids":["https://openalex.org/I4210150388"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008741834","display_name":"C. W. Smith","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210150388","display_name":"Velindre Cancer Centre","ror":"https://ror.org/049sr1d03","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799279586","https://openalex.org/I4210150388"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"C.W. Smith","raw_affiliation_strings":["South Wales Radiotherapy and Oncology Service, Velindre Hospital, Cardiff, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"South Wales Radiotherapy and Oncology Service, Velindre Hospital, Cardiff, United Kingdom","institution_ids":["https://openalex.org/I4210150388"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210150388"],"apc_list":{"value":7890,"currency":"USD","value_usd":7890},"apc_paid":null,"fwci":18.952,"has_fulltext":false,"cited_by_count":235,"citation_normalized_percentile":{"value":0.99710313,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"310","issue":"8029","first_page":"101","last_page":"103"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10631","display_name":"Cancer, Hypoxia, and Metabolism","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hyperbaric-oxygen-therapy","display_name":"hyperbaric oxygen therapy","score":0.9800000190734863},{"id":"https://openalex.org/keywords/head-and-neck-cancer","display_name":"head and neck cancer","score":0.9660000205039978},{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.800000011920929},{"id":"https://openalex.org/keywords/adjuvant-therapy","display_name":"adjuvant therapy","score":0.9120000004768372},{"id":"https://openalex.org/keywords/local-tumor-control","display_name":"local tumor control","score":0.9610000252723694},{"id":"https://openalex.org/keywords/salvage-surgery","display_name":"salvage surgery","score":0.9390000104904175},{"id":"https://openalex.org/keywords/laryngeal-cartilages","display_name":"laryngeal cartilages","score":0.9869999885559082},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.7329999804496765}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8167743682861328},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.8022381663322449},{"id":"https://openalex.org/C2994405533","wikidata":"https://www.wikidata.org/wiki/Q731615","display_name":"Hyperbaric oxygen","level":2,"score":0.7252362370491028},{"id":"https://openalex.org/C2776530083","wikidata":"https://www.wikidata.org/wiki/Q1783924","display_name":"Head and neck cancer","level":3,"score":0.5902395844459534},{"id":"https://openalex.org/C3018411727","wikidata":"https://www.wikidata.org/wiki/Q3867488","display_name":"Head and neck","level":2,"score":0.47342756390571594},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.46051183342933655},{"id":"https://openalex.org/C3018454096","wikidata":"https://www.wikidata.org/wiki/Q2481887","display_name":"Adjuvant radiotherapy","level":3,"score":0.45414280891418457},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.44047772884368896},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.44043049216270447},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.06761601567268372},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006258","descriptor_name":"Head and Neck Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D006258","descriptor_name":"Head and Neck Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D006258","descriptor_name":"Head and Neck Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006931","descriptor_name":"Hyperbaric Oxygenation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007822","descriptor_name":"Laryngeal Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009062","descriptor_name":"Mouth Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D009669","descriptor_name":"Nose Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D010610","descriptor_name":"Pharyngeal Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011879","descriptor_name":"Radiotherapy Dosage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0140-6736(77)90116-7","doi":"https://doi.org/10.1016/s0140-6736(77)90116-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0140-6736(77)90116-7","pdf_url":null,"source":{"id":"https://openalex.org/S49861241","display_name":"The Lancet","issn_l":"0099-5355","issn":["0099-5355","0140-6736","1474-547X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet","raw_type":"journal-article"},{"id":"pmid:69191","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/69191","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lancet (London, England)","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1860272291","https://openalex.org/W1943977034","https://openalex.org/W1972885575","https://openalex.org/W1996260317","https://openalex.org/W2007145715","https://openalex.org/W2049369071","https://openalex.org/W2056917217","https://openalex.org/W2061004798","https://openalex.org/W2070961524","https://openalex.org/W2106854568","https://openalex.org/W2136393068","https://openalex.org/W2144833146","https://openalex.org/W2147165905","https://openalex.org/W2157607856","https://openalex.org/W2313321548","https://openalex.org/W2616852889","https://openalex.org/W4298434897","https://openalex.org/W4298721761"],"related_works":["https://openalex.org/W2313321548","https://openalex.org/W2138326684","https://openalex.org/W2004009879","https://openalex.org/W4255015381","https://openalex.org/W1992116891","https://openalex.org/W155017870","https://openalex.org/W2101317014","https://openalex.org/W2031625972","https://openalex.org/W2120657219","https://openalex.org/W2433413551"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":4},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}