{"id":"https://openalex.org/W2013707620","doi":"https://doi.org/10.1111/j.1471-4159.1974.tb10753.x","title":"THE UPTAKE OF 36Cl INTO ASTROCYTES IN TISSUE CULTURE BY A POTASSIUM\u2010DEPENDENT, SATURABLE PROCESS","display_name":"THE UPTAKE OF 36Cl INTO ASTROCYTES IN TISSUE CULTURE BY A POTASSIUM\u2010DEPENDENT, SATURABLE PROCESS","publication_year":1974,"publication_date":"1974-11-01","ids":{"openalex":"https://openalex.org/W2013707620","doi":"https://doi.org/10.1111/j.1471-4159.1974.tb10753.x","mag":"2013707620","pmid":"https://pubmed.ncbi.nlm.nih.gov/4373536"},"language":"en","primary_location":{"id":"doi:10.1111/j.1471-4159.1974.tb10753.x","doi":"https://doi.org/10.1111/j.1471-4159.1974.tb10753.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1471-4159.1974.tb10753.x","pdf_url":null,"source":{"id":"https://openalex.org/S135837084","display_name":"Journal of Neurochemistry","issn_l":"0022-3042","issn":["0022-3042","1471-4159"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"T. H. Gill","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I181233156","display_name":"University of Oregon","ror":"https://ror.org/0293rh119","country_code":"US","type":"education","lineage":["https://openalex.org/I181233156"]},{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T. H. Gill","raw_affiliation_strings":["Department of Pathology, University of Oregon Medical School, Portland, OR 97201, U.S.A","Laboratory of Neurochemistry, National Institute of Neurological Diseases and Stroke, Bethesda, MD 20014, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Oregon Medical School, Portland, OR 97201, U.S.A","institution_ids":["https://openalex.org/I165690674","https://openalex.org/I181233156"]},{"raw_affiliation_string":"Laboratory of Neurochemistry, National Institute of Neurological Diseases and Stroke, Bethesda, MD 20014, U.S.A","institution_ids":["https://openalex.org/I4210110767"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006566280","display_name":"Oscar M. Young","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"O. M. Young","raw_affiliation_strings":["Laboratory of Neurochemistry, National Institute of Neurological Diseases and Stroke, Bethesda, MD 20014, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Neurochemistry, National Institute of Neurological Diseases and Stroke, Bethesda, MD 20014, U.S.A","institution_ids":["https://openalex.org/I4210110767"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113630535","display_name":"D. B. Tower","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210110767","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210110767"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. B. Tower","raw_affiliation_strings":["Laboratory of Neurochemistry, National Institute of Neurological Diseases and Stroke, Bethesda, MD 20014, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Neurochemistry, National Institute of Neurological Diseases and Stroke, Bethesda, MD 20014, U.S.A","institution_ids":["https://openalex.org/I4210110767"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5330,"currency":"USD","value_usd":5330},"apc_paid":null,"fwci":1.9423,"has_fulltext":false,"cited_by_count":56,"citation_normalized_percentile":{"value":0.8488348,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"23","issue":"5","first_page":"1011","last_page":"1018"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.00559999980032444,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chloride-uptake","display_name":"chloride uptake","score":0.8769999742507935},{"id":"https://openalex.org/keywords/astrocytes","display_name":"astrocytes","score":0.9829999804496765},{"id":"https://openalex.org/keywords/cerebral-cortex","display_name":"cerebral cortex","score":0.4390000104904175},{"id":"https://openalex.org/keywords/neuroblastoma-cells","display_name":"neuroblastoma cells","score":0.7429999709129333},{"id":"https://openalex.org/keywords/acetazolamide-inhibition","display_name":"acetazolamide inhibition","score":0.7950000166893005},{"id":"https://openalex.org/keywords/na-k-ratio","display_name":"Na+/K+ ratio","score":0.6520000100135803},{"id":"https://openalex.org/keywords/extracellular-space","display_name":"extracellular space","score":0.6449999809265137},{"id":"https://openalex.org/keywords/epilepsy","display_name":"epilepsy","score":0.3190000057220459},{"id":"https://openalex.org/keywords/stroke","display_name":"stroke","score":0.9330000281333923},{"id":"https://openalex.org/keywords/cortical-edema","display_name":"cortical edema","score":0.9670000076293945}],"concepts":[{"id":"https://openalex.org/C537181965","wikidata":"https://www.wikidata.org/wiki/Q658","display_name":"Sodium","level":2,"score":0.6098986268043518},{"id":"https://openalex.org/C28406088","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Extracellular","level":2,"score":0.5758892297744751},{"id":"https://openalex.org/C2778695967","wikidata":"https://www.wikidata.org/wiki/Q44791900","display_name":"Chloride","level":2,"score":0.567007303237915},{"id":"https://openalex.org/C517785266","wikidata":"https://www.wikidata.org/wiki/Q703","display_name":"Potassium","level":2,"score":0.5418752431869507},{"id":"https://openalex.org/C2777405951","wikidata":"https://www.wikidata.org/wiki/Q413690","display_name":"Acetazolamide","level":2,"score":0.5393860340118408},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5116565823554993},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.49816203117370605},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.4937926232814789},{"id":"https://openalex.org/C2778575167","wikidata":"https://www.wikidata.org/wiki/Q6573","display_name":"Hamster","level":2,"score":0.4486605226993561},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.4273689389228821},{"id":"https://openalex.org/C2776715637","wikidata":"https://www.wikidata.org/wiki/Q938205","display_name":"Neuroblastoma","level":3,"score":0.42662182450294495},{"id":"https://openalex.org/C2777542381","wikidata":"https://www.wikidata.org/wiki/Q502961","display_name":"Astrocyte","level":3,"score":0.421808123588562},{"id":"https://openalex.org/C90703135","wikidata":"https://www.wikidata.org/wiki/Q3287622","display_name":"Tissue culture","level":3,"score":0.4202273190021515},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3769240975379944},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.37008777260780334},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.36901992559432983},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3088494539260864},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2782430350780487},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.26805979013442993},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.09272423386573792},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000086","descriptor_name":"Acetazolamide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001253","descriptor_name":"Astrocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001253","descriptor_name":"Astrocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001253","descriptor_name":"Astrocytes","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D001692","descriptor_name":"Biological Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001965","descriptor_name":"Bromides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002540","descriptor_name":"Cerebral Cortex","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002712","descriptor_name":"Chlorides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002713","descriptor_name":"Chlorine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002999","descriptor_name":"Clone Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004140","descriptor_name":"Dinitrophenols","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005459","descriptor_name":"Fluorides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D006224","descriptor_name":"Cricetinae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007454","descriptor_name":"Iodides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007457","descriptor_name":"Iodine Radioisotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009447","descriptor_name":"Neuroblastoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009457","descriptor_name":"Neuroglia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010472","descriptor_name":"Perchlorates","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011188","descriptor_name":"Potassium","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011868","descriptor_name":"Radioisotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013861","descriptor_name":"Thiocyanates","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1471-4159.1974.tb10753.x","doi":"https://doi.org/10.1111/j.1471-4159.1974.tb10753.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1471-4159.1974.tb10753.x","pdf_url":null,"source":{"id":"https://openalex.org/S135837084","display_name":"Journal of Neurochemistry","issn_l":"0022-3042","issn":["0022-3042","1471-4159"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurochemistry","raw_type":"journal-article"},{"id":"pmid:4373536","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4373536","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neurochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":58,"referenced_works":["https://openalex.org/W204980459","https://openalex.org/W1508621167","https://openalex.org/W1584413404","https://openalex.org/W1604444942","https://openalex.org/W1775749144","https://openalex.org/W1844740521","https://openalex.org/W1864765563","https://openalex.org/W1970683644","https://openalex.org/W1983027746","https://openalex.org/W1986348317","https://openalex.org/W1986649686","https://openalex.org/W1993718011","https://openalex.org/W1996165088","https://openalex.org/W1997113794","https://openalex.org/W1999765805","https://openalex.org/W2001841360","https://openalex.org/W2001907279","https://openalex.org/W2002057610","https://openalex.org/W2002120952","https://openalex.org/W2002458506","https://openalex.org/W2003505985","https://openalex.org/W2007214804","https://openalex.org/W2008978687","https://openalex.org/W2010935103","https://openalex.org/W2024688918","https://openalex.org/W2034457899","https://openalex.org/W2036602611","https://openalex.org/W2046140783","https://openalex.org/W2053654911","https://openalex.org/W2053692112","https://openalex.org/W2054295655","https://openalex.org/W2054682108","https://openalex.org/W2057201961","https://openalex.org/W2057632590","https://openalex.org/W2057814279","https://openalex.org/W2059684032","https://openalex.org/W2070246424","https://openalex.org/W2070956353","https://openalex.org/W2078349619","https://openalex.org/W2079374796","https://openalex.org/W2081528824","https://openalex.org/W2082537383","https://openalex.org/W2085069835","https://openalex.org/W2085264280","https://openalex.org/W2118262335","https://openalex.org/W2147167765","https://openalex.org/W2147717385","https://openalex.org/W2154367489","https://openalex.org/W2169712414","https://openalex.org/W2206678636","https://openalex.org/W2277024590","https://openalex.org/W2309240847","https://openalex.org/W2330423281","https://openalex.org/W2436344219","https://openalex.org/W2441506123","https://openalex.org/W2461064090","https://openalex.org/W4211142504","https://openalex.org/W4232464497"],"related_works":["https://openalex.org/W2012640937","https://openalex.org/W2062228760","https://openalex.org/W2082537383","https://openalex.org/W2028977278","https://openalex.org/W2037360023","https://openalex.org/W2061707586","https://openalex.org/W2064190341","https://openalex.org/W2093589803","https://openalex.org/W2045993824","https://openalex.org/W1981133890"],"abstract_inverted_index":{"Abstract\u2014":[0],"Previous":[1],"suggestions":[2,218],"that":[3,219,236],"the":[4,64,83,90,96,104,107,167,172,176,186,195,200,210,260,265],"K+\u2010dependent":[5,224],"uptake":[6,86,108,122,230,238],"of":[7,24,66,73,85,87,95,98,118,152,171,179,184,251,264,272],"chloride":[8,227],"by":[9,89,111,131,144,231],"mammalian":[10,232],"cerebral":[11],"cortex":[12],"is":[13,221,239],"localized":[14],"to":[15,181,212],"cortical":[16,278],"astrocytes":[17,31,91,173,257],"has":[18],"been":[19,247],"investigated":[20],"in":[21,27,44,63,103,249,258,270],"two":[22],"lines":[23],"neural":[25],"cells":[26,35,196],"tissue":[28],"culture.":[29],"Hamster":[30],"and":[32,106,114,125,141,194,228,235,269,277],"mouse":[33],"neuroblastoma":[34,158],"were":[36,56,155],"each":[37],"cultured":[38],"on":[39],"small":[40],"glass":[41],"cover":[42,201],"slips":[43,202],"Eagle's":[45],"(astrocytes)":[46],"or":[47,133,139],"Dulbecco's":[48],"(neuroblastoma)":[49],"supplemented":[50],"media.":[51],"At":[52],"48":[53],"h,":[54],"cultures":[55,159],"incubated":[57],"at":[58],"37\u00b0C":[59],"for":[60,216,256,274],"1\u201360":[61],"min":[62],"presence":[65],"36Cl":[67,88],"plus":[68],"[3H]inulin":[69],"(as":[70],"a":[71,93,182,222,252],"measure":[72],"extracellular":[74],"space).":[75],"In":[76,164],"media":[77],"containing":[78],"approximately":[79],"140":[80],"mm":[81,135,146],"chloride,":[82],"rate":[84],"was":[92,109,123],"function":[94],"concentration":[97],"K+":[99],"(range":[100],"5\u201354":[101],"mm)":[102],"medium,":[105],"characterized":[110],"saturation":[112],"kinetics":[113],"an":[115,240],"apparent":[116],"Km":[117],"38\u00b75":[119],"mm.":[120],"The":[121,244],"temperature":[124],"apparently":[126],"energy":[127],"dependent,":[128],"significantly":[129],"inhibited":[130,143],"5":[132],"10":[134,145],"Br\u2010,":[136],"I\u2010,":[137],"SCN\u2010":[138],"ClO4\u2010,":[140],"competitively":[142],"acetazolamide":[147],"(Ki=":[148],"27\u00b71":[149],"mm).":[150],"None":[151],"these":[153],"characteristics":[154],"observed":[156],"with":[157],"studied":[160],"under":[161],"similar":[162],"conditions.":[163],"chloride\u2010free":[165],"media,":[166],"cellular":[168],"K/Na":[169],"ratio":[170],"shifted":[174],"from":[175,199],"usual":[177],"value":[178,183],"4\u00b755":[180],"0\u00b729,":[185],"culture":[187],"medium":[188],"became":[189],"more":[190],"alkaline":[191],"than":[192],"normal,":[193],"spontaneously":[197],"sloughed":[198],"but":[203],"remained":[204],"normally":[205],"viable.":[206],"Our":[207],"observations":[208,245],"are":[209],"first":[211],"provide":[213],"direct":[214],"support":[215],"previous":[217],"there":[220],"mediated,":[223],"coupled":[225],"cation,":[226],"fluid":[229],"cerebrocortical":[233],"glia":[234],"this":[237],"enzymatically":[241],"catalysed":[242],"process.":[243],"have":[246],"discussed":[248],"terms":[250,271],"presumed":[253],"central":[254],"role":[255],"modulating":[259],"external":[261],"ionic":[262],"milieu":[263],"neurons":[266],"they":[267],"surround":[268],"implications":[273],"epilepsy,":[275],"stroke":[276],"edema.":[279]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}