{"id":"https://openalex.org/W2013603242","doi":"https://doi.org/10.1016/s0006-8993(02)03576-x","title":"GABA-ergic innervation of thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus of the rat","display_name":"GABA-ergic innervation of thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus of the rat","publication_year":2002,"publication_date":"2002-12-01","ids":{"openalex":"https://openalex.org/W2013603242","doi":"https://doi.org/10.1016/s0006-8993(02)03576-x","mag":"2013603242","pmid":"https://pubmed.ncbi.nlm.nih.gov/12445967"},"language":"en","primary_location":{"id":"doi:10.1016/s0006-8993(02)03576-x","doi":"https://doi.org/10.1016/s0006-8993(02)03576-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0006-8993(02)03576-x","pdf_url":null,"source":{"id":"https://openalex.org/S96638545","display_name":"Brain Research","issn_l":"0006-8993","issn":["0006-8993","1872-6240"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001902256","display_name":"Csaba Fekete","orcid":"https://orcid.org/0000-0002-8206-562X","observed_orcids":["https://orcid.org/0000-0002-8206-562X"]},"institutions":[{"id":"https://openalex.org/I4210106880","display_name":"HUN-REN Institute of Experimental Medicine","ror":"https://ror.org/01jsgmp44","country_code":"HU","type":"facility","lineage":["https://openalex.org/I4210106880","https://openalex.org/I4387152226"]},{"id":"https://openalex.org/I7597260","display_name":"Hungarian Academy of Sciences","ror":"https://ror.org/02ks8qq67","country_code":"HU","type":"government","lineage":["https://openalex.org/I7597260"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Csaba Fekete","raw_affiliation_strings":["Department of Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary","institution_ids":["https://openalex.org/I4210106880","https://openalex.org/I7597260"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029470979","display_name":"G\u00e1bor Wittmann","orcid":"https://orcid.org/0000-0003-0747-6813","observed_orcids":["https://orcid.org/0000-0003-0747-6813"]},"institutions":[{"id":"https://openalex.org/I4210106880","display_name":"HUN-REN Institute of Experimental Medicine","ror":"https://ror.org/01jsgmp44","country_code":"HU","type":"facility","lineage":["https://openalex.org/I4210106880","https://openalex.org/I4387152226"]},{"id":"https://openalex.org/I7597260","display_name":"Hungarian Academy of Sciences","ror":"https://ror.org/02ks8qq67","country_code":"HU","type":"government","lineage":["https://openalex.org/I7597260"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"G\u00e1bor Wittmann","raw_affiliation_strings":["Department of Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest 1083, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest 1083, Hungary","institution_ids":["https://openalex.org/I4210106880","https://openalex.org/I7597260"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010088706","display_name":"Zsolt Liposits","orcid":"https://orcid.org/0000-0002-3508-2750","observed_orcids":["https://orcid.org/0000-0002-3508-2750"]},"institutions":[{"id":"https://openalex.org/I4210106880","display_name":"HUN-REN Institute of Experimental Medicine","ror":"https://ror.org/01jsgmp44","country_code":"HU","type":"facility","lineage":["https://openalex.org/I4210106880","https://openalex.org/I4387152226"]},{"id":"https://openalex.org/I7597260","display_name":"Hungarian Academy of Sciences","ror":"https://ror.org/02ks8qq67","country_code":"HU","type":"government","lineage":["https://openalex.org/I7597260"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Zsolt Liposits","raw_affiliation_strings":["Department of Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest 1083, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurobiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest 1083, Hungary","institution_ids":["https://openalex.org/I4210106880","https://openalex.org/I7597260"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077497900","display_name":"Ronald Michael Lechan","orcid":"https://orcid.org/0000-0003-0404-2323","observed_orcids":["https://orcid.org/0000-0003-0404-2323"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I1290900354","display_name":"Tufts Medical Center","ror":"https://ror.org/002hsbm82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1290900354"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ronald M Lechan","raw_affiliation_strings":["Department of Neuroscience, Tufts University School of Medicine, 750 Washington St. Box No. 268, Boston, MA 02111, USA","Tupper Research Institute and Department of Medicine, Division of Endocrinology, Diabetes, Metabolism and Molecular Medicine, Tufts New England Medical Center, 750 Washington St. Box No. 268, Boston, MA 02111, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Tufts University School of Medicine, 750 Washington St. Box No. 268, Boston, MA 02111, USA","institution_ids":["https://openalex.org/I121934306"]},{"raw_affiliation_string":"Tupper Research Institute and Department of Medicine, Division of Endocrinology, Diabetes, Metabolism and Molecular Medicine, Tufts New England Medical Center, 750 Washington St. Box No. 268, Boston, MA 02111, USA","institution_ids":["https://openalex.org/I1290900354"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5077497900"],"corresponding_institution_ids":["https://openalex.org/I121934306","https://openalex.org/I1290900354"],"apc_list":{"value":3360,"currency":"USD","value_usd":3360},"apc_paid":null,"fwci":0.5809,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.57743069,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"957","issue":"2","first_page":"251","last_page":"258"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.5015000104904175,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.5015000104904175,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.25780001282691956,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.2012999951839447,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gabaergic-innervation","display_name":"GABAergic innervation","score":0.9589999914169312},{"id":"https://openalex.org/keywords/paraventricular-nucleus","display_name":"paraventricular nucleus","score":0.906000018119812},{"id":"https://openalex.org/keywords/glutamic-acid-decarboxylase","display_name":"glutamic acid decarboxylase","score":0.9509999752044678},{"id":"https://openalex.org/keywords/neuropeptide-y","display_name":"neuropeptide Y","score":0.9470000267028809},{"id":"https://openalex.org/keywords/arcuate-nucleus","display_name":"arcuate nucleus","score":0.9210000038146973},{"id":"https://openalex.org/keywords/inhibitory-synapses","display_name":"inhibitory synapses","score":0.7120000123977661},{"id":"https://openalex.org/keywords/axonal-varicosities","display_name":"axonal varicosities","score":0.7229999899864197},{"id":"https://openalex.org/keywords/hypothalamic-pituitary-axis","display_name":"hypothalamic-pituitary axis","score":0.699999988079071}],"concepts":[{"id":"https://openalex.org/C2778458369","wikidata":"https://www.wikidata.org/wiki/Q253246","display_name":"Arcuate nucleus","level":3,"score":0.7182862758636475},{"id":"https://openalex.org/C35866371","wikidata":"https://www.wikidata.org/wiki/Q6005502","display_name":"Immunocytochemistry","level":2,"score":0.6721667051315308},{"id":"https://openalex.org/C2780723820","wikidata":"https://www.wikidata.org/wiki/Q1934178","display_name":"Nucleus","level":2,"score":0.6066133975982666},{"id":"https://openalex.org/C2776216936","wikidata":"https://www.wikidata.org/wiki/Q24726011","display_name":"Thyrotropin-releasing hormone","level":3,"score":0.5581640005111694},{"id":"https://openalex.org/C9497952","wikidata":"https://www.wikidata.org/wiki/Q419650","display_name":"Glutamate decarboxylase","level":3,"score":0.5497326850891113},{"id":"https://openalex.org/C2779530196","wikidata":"https://www.wikidata.org/wiki/Q178999","display_name":"Axon","level":2,"score":0.5444076061248779},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5095201134681702},{"id":"https://openalex.org/C2777003273","wikidata":"https://www.wikidata.org/wiki/Q164386","display_name":"Hypothalamus","level":2,"score":0.4925268590450287},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.47048500180244446},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.45565366744995117},{"id":"https://openalex.org/C118303440","wikidata":"https://www.wikidata.org/wiki/Q419968","display_name":"Neuropeptide","level":3,"score":0.4451519250869751},{"id":"https://openalex.org/C121731113","wikidata":"https://www.wikidata.org/wiki/Q7141373","display_name":"Parvocellular cell","level":3,"score":0.4393322169780731},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4008728265762329},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.32567155361175537},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.22218236327171326},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.18224593997001648},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.06063970923423767},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000344","descriptor_name":"Afferent Pathways","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000344","descriptor_name":"Afferent Pathways","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001111","descriptor_name":"Arcuate Nucleus of Hypothalamus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001111","descriptor_name":"Arcuate Nucleus of Hypothalamus","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D003712","descriptor_name":"Dendrites","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003712","descriptor_name":"Dendrites","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005508","descriptor_name":"Food Deprivation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005680","descriptor_name":"gamma-Aminobutyric Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005968","descriptor_name":"Glutamate Decarboxylase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007030","descriptor_name":"Hypothalamo-Hypophyseal System","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007030","descriptor_name":"Hypothalamo-Hypophyseal System","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009433","descriptor_name":"Neural Inhibition","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009478","descriptor_name":"Neuropeptide Y","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010286","descriptor_name":"Paraventricular Hypothalamic Nucleus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010286","descriptor_name":"Paraventricular Hypothalamic Nucleus","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D013963","descriptor_name":"Thyroid Hormones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013973","descriptor_name":"Thyrotropin-Releasing Hormone","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D013973","descriptor_name":"Thyrotropin-Releasing Hormone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017729","descriptor_name":"Presynaptic Terminals","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017729","descriptor_name":"Presynaptic Terminals","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0006-8993(02)03576-x","doi":"https://doi.org/10.1016/s0006-8993(02)03576-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0006-8993(02)03576-x","pdf_url":null,"source":{"id":"https://openalex.org/S96638545","display_name":"Brain Research","issn_l":"0006-8993","issn":["0006-8993","1872-6240"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Research","raw_type":"journal-article"},{"id":"pmid:12445967","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12445967","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.428600013256073,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1268908064","display_name":null,"funder_award_id":"DK 37021","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G5126911581","display_name":"CART AND THE HYPOTHALAMIC-PITUITARY-THYROID AXIS","funder_award_id":"5r03tw001494-03","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5999628863","display_name":null,"funder_award_id":"TW01494","funder_id":"https://openalex.org/F4320337356","funder_display_name":"Fogarty International Center"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337356","display_name":"Fogarty International Center","ror":"https://ror.org/02xey9a22"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W1483887312","https://openalex.org/W1504054592","https://openalex.org/W1516501072","https://openalex.org/W1530537034","https://openalex.org/W1955394373","https://openalex.org/W1958860054","https://openalex.org/W1975347123","https://openalex.org/W1986413865","https://openalex.org/W1988005306","https://openalex.org/W1988819654","https://openalex.org/W1992841732","https://openalex.org/W1993361286","https://openalex.org/W1993563186","https://openalex.org/W1993602125","https://openalex.org/W2015237616","https://openalex.org/W2019223615","https://openalex.org/W2022713347","https://openalex.org/W2024794762","https://openalex.org/W2027392619","https://openalex.org/W2028110564","https://openalex.org/W2031929672","https://openalex.org/W2034546665","https://openalex.org/W2040180486","https://openalex.org/W2052948801","https://openalex.org/W2061128822","https://openalex.org/W2064183906","https://openalex.org/W2066543142","https://openalex.org/W2068555170","https://openalex.org/W2072886744","https://openalex.org/W2083118347","https://openalex.org/W2085205986","https://openalex.org/W2094868917","https://openalex.org/W2131841257","https://openalex.org/W2156147980","https://openalex.org/W2159171051","https://openalex.org/W2315654621","https://openalex.org/W2328797810","https://openalex.org/W2400961431"],"related_works":["https://openalex.org/W2079963999","https://openalex.org/W2982550910","https://openalex.org/W2069399632","https://openalex.org/W2039667783","https://openalex.org/W2023234701","https://openalex.org/W1992841732","https://openalex.org/W2061005803","https://openalex.org/W2030757576","https://openalex.org/W1964700389","https://openalex.org/W2004881152"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}