{"id":"https://openalex.org/W201355320","doi":"https://doi.org/10.1007/bf00916551","title":"Host defense againstMycobacterium-avium complex","display_name":"Host defense againstMycobacterium-avium complex","publication_year":1988,"publication_date":"1988-07-01","ids":{"openalex":"https://openalex.org/W201355320","doi":"https://doi.org/10.1007/bf00916551","mag":"201355320","pmid":"https://pubmed.ncbi.nlm.nih.gov/2842366"},"language":"en","primary_location":{"id":"doi:10.1007/bf00916551","doi":"https://doi.org/10.1007/bf00916551","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00916551","pdf_url":null,"source":{"id":"https://openalex.org/S57504206","display_name":"Journal of Clinical Immunology","issn_l":"0271-9142","issn":["0271-9142","1573-2592"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109094913","display_name":"Steven Schnittman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven Schnittman","raw_affiliation_strings":["Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892","Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892","institution_ids":["https://openalex.org/I4210134534"]},{"raw_affiliation_string":"Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda,","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017815904","display_name":"Henry Clifford Lane","orcid":"https://orcid.org/0000-0001-9509-1045","observed_orcids":["https://orcid.org/0000-0001-9509-1045"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. Clifford Lane","raw_affiliation_strings":["Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 20892, Bethesda, Maryland","Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 20892, Bethesda, Maryland","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]},{"raw_affiliation_string":"Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda,","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050714934","display_name":"Frank G. Witebsky","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210155647","display_name":"National Institutes of Health Clinical Center","ror":"https://ror.org/04vfsmv21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Frank G. Witebsky","raw_affiliation_strings":["Clinical Pathology Department, Clinical Center, National Institutes of Health, 20892, Bethesda, Maryland","Clinical Pathology Department, Clinical Center, National Institutes of Health, Bethesda"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Pathology Department, Clinical Center, National Institutes of Health, 20892, Bethesda, Maryland","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210155647"]},{"raw_affiliation_string":"Clinical Pathology Department, Clinical Center, National Institutes of Health, Bethesda","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109214138","display_name":"Linda L. Gosey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210155647","display_name":"National Institutes of Health Clinical Center","ror":"https://ror.org/04vfsmv21","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Linda L. Gosey","raw_affiliation_strings":["Clinical Pathology Department, Clinical Center, National Institutes of Health, 20892, Bethesda, Maryland","Clinical Pathology Department, Clinical Center, National Institutes of Health, Bethesda"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Pathology Department, Clinical Center, National Institutes of Health, 20892, Bethesda, Maryland","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210155647"]},{"raw_affiliation_string":"Clinical Pathology Department, Clinical Center, National Institutes of Health, Bethesda","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210155647"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013039553","display_name":"M. DAVID HOGGAN","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. David Hoggan","raw_affiliation_strings":["Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 20892, Bethesda, Maryland","Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 20892, Bethesda, Maryland","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]},{"raw_affiliation_string":"Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda,","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031736334","display_name":"Anthony S. Fauci","orcid":"https://orcid.org/0000-0002-7865-7235","observed_orcids":["https://orcid.org/0000-0002-7865-7235"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anthony S. Fauci","raw_affiliation_strings":["Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 20892, Bethesda, Maryland","Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 20892, Bethesda, Maryland","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]},{"raw_affiliation_string":"Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda,","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4990,"currency":"USD","value_usd":4990},"apc_paid":null,"fwci":5.6812,"has_fulltext":false,"cited_by_count":49,"citation_normalized_percentile":{"value":0.95732049,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"8","issue":"4","first_page":"234","last_page":"243"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11316","display_name":"Mycobacterium research and diagnosis","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11316","display_name":"Mycobacterium research and diagnosis","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11381","display_name":"Infectious Diseases and Tuberculosis","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mycobacterium-avium-complex","display_name":"Mycobacterium avium complex","score":0.9980000257492065},{"id":"https://openalex.org/keywords/aids","display_name":"AIDS","score":0.6100000143051147},{"id":"https://openalex.org/keywords/disseminated-mac-infection","display_name":"disseminated MAC infection","score":0.8619999885559082},{"id":"https://openalex.org/keywords/host-defense-defects","display_name":"host defense defects","score":0.7889999747276306},{"id":"https://openalex.org/keywords/monocytes","display_name":"monocytes","score":0.8109999895095825},{"id":"https://openalex.org/keywords/phagocytosis","display_name":"phagocytosis","score":0.9769999980926514},{"id":"https://openalex.org/keywords/superoxide-production","display_name":"superoxide production","score":0.9660000205039978},{"id":"https://openalex.org/keywords/bacterial-killing-kinetics","display_name":"bacterial killing kinetics","score":0.6190000176429749},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.9520000219345093},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9990000128746033},{"id":"https://openalex.org/keywords/interleukin-2","display_name":"interleukin-2","score":0.9110000133514404},{"id":"https://openalex.org/keywords/antibody-mediated-killing","display_name":"antibody-mediated killing","score":0.7239999771118164},{"id":"https://openalex.org/keywords/polymyositis","display_name":"polymyositis","score":0.824999988079071},{"id":"https://openalex.org/keywords/immunocompromised-patients","display_name":"immunocompromised patients","score":0.652999997138977}],"concepts":[{"id":"https://openalex.org/C190139176","wikidata":"https://www.wikidata.org/wiki/Q598976","display_name":"Medical microbiology","level":2,"score":0.6030459403991699},{"id":"https://openalex.org/C126831891","wikidata":"https://www.wikidata.org/wiki/Q221673","display_name":"Host (biology)","level":2,"score":0.46223124861717224},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4475496709346771},{"id":"https://openalex.org/C2781455004","wikidata":"https://www.wikidata.org/wiki/Q3311330","display_name":"Mycobacterium avium complex","level":2,"score":0.44010287523269653},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.42101380228996277},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.35354894399642944},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.35002511739730835},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.32081133127212524},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.25059258937835693}],"mesh":[{"descriptor_ui":"D000276","descriptor_name":"Adjuvants, Immunologic","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D003602","descriptor_name":"Cytotoxicity, Immunologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007106","descriptor_name":"Immune Sera","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007113","descriptor_name":"Immunity, Innate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009162","descriptor_name":"Mycobacterium avium","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D010587","descriptor_name":"Phagocytosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013481","descriptor_name":"Superoxides","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D014376","descriptor_name":"Tuberculosis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D014376","descriptor_name":"Tuberculosis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf00916551","doi":"https://doi.org/10.1007/bf00916551","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00916551","pdf_url":null,"source":{"id":"https://openalex.org/S57504206","display_name":"Journal of Clinical Immunology","issn_l":"0271-9142","issn":["0271-9142","1573-2592"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Immunology","raw_type":"journal-article"},{"id":"pmid:2842366","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2842366","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical immunology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.8399999737739563,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W1820832","https://openalex.org/W257777918","https://openalex.org/W1501828225","https://openalex.org/W1503022370","https://openalex.org/W1864777644","https://openalex.org/W1923435690","https://openalex.org/W1930779565","https://openalex.org/W1974401900","https://openalex.org/W1981753754","https://openalex.org/W1995277163","https://openalex.org/W2014696818","https://openalex.org/W2016554549","https://openalex.org/W2026588653","https://openalex.org/W2033962378","https://openalex.org/W2036046048","https://openalex.org/W2049402938","https://openalex.org/W2050358929","https://openalex.org/W2074387820","https://openalex.org/W2087790020","https://openalex.org/W2092973954","https://openalex.org/W2116168633","https://openalex.org/W2162206620","https://openalex.org/W2162822989","https://openalex.org/W2166305071","https://openalex.org/W2192032207","https://openalex.org/W2225633666","https://openalex.org/W2237403372","https://openalex.org/W2319153630","https://openalex.org/W2321232203","https://openalex.org/W2328590806","https://openalex.org/W2334923455","https://openalex.org/W2405533973","https://openalex.org/W2410439354","https://openalex.org/W2415130926","https://openalex.org/W2424507589","https://openalex.org/W2435874225","https://openalex.org/W3020963154","https://openalex.org/W4256356205","https://openalex.org/W4301868472"],"related_works":["https://openalex.org/W2028899046","https://openalex.org/W2413765641","https://openalex.org/W2155186392","https://openalex.org/W4313383497","https://openalex.org/W1587195158","https://openalex.org/W2022629108","https://openalex.org/W2412099400","https://openalex.org/W2067610643","https://openalex.org/W2022780664","https://openalex.org/W4309852321"],"abstract_inverted_index":null,"counts_by_year":[{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}