{"id":"https://openalex.org/W2013342412","doi":"https://doi.org/10.1016/s0166-6851(00)00281-4","title":"The cytoadherence ligand Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) binds to the P. falciparum Knob-associated Histidine-rich Protein (KAHRP) by electrostatic interactions","display_name":"The cytoadherence ligand Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) binds to the P. falciparum Knob-associated Histidine-rich Protein (KAHRP) by electrostatic interactions","publication_year":2000,"publication_date":"2000-10-01","ids":{"openalex":"https://openalex.org/W2013342412","doi":"https://doi.org/10.1016/s0166-6851(00)00281-4","mag":"2013342412","pmid":"https://pubmed.ncbi.nlm.nih.gov/11071296"},"language":"en","primary_location":{"id":"doi:10.1016/s0166-6851(00)00281-4","doi":"https://doi.org/10.1016/s0166-6851(00)00281-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0166-6851(00)00281-4","pdf_url":null,"source":{"id":"https://openalex.org/S144099348","display_name":"Molecular and Biochemical Parasitology","issn_l":"0166-6851","issn":["0166-6851","1872-9428"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Biochemical Parasitology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087774699","display_name":"Sabine Voigt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I3018163063","display_name":"St. Elizabeth's Medical Center","ror":"https://ror.org/00cr15z55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3018163063"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sabine Voigt","raw_affiliation_strings":["Department of Medicine, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA. voigt@cbr.med.harvard.edu","Section of Oncology/Hematology Research, Departments of Medicine, Anatomy and Cellular Biology, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA. voigt@cbr.med.harvard.edu","institution_ids":["https://openalex.org/I121934306","https://openalex.org/I3018163063"]},{"raw_affiliation_string":"Section of Oncology/Hematology Research, Departments of Medicine, Anatomy and Cellular Biology, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA","institution_ids":["https://openalex.org/I121934306","https://openalex.org/I3018163063"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061672499","display_name":"Manjit Hanspal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I3018163063","display_name":"St. Elizabeth's Medical Center","ror":"https://ror.org/00cr15z55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3018163063"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Manjit Hanspal","raw_affiliation_strings":["Section of Oncology/Hematology Research, Departments of Medicine, Anatomy and Cellular Biology, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Oncology/Hematology Research, Departments of Medicine, Anatomy and Cellular Biology, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA","institution_ids":["https://openalex.org/I121934306","https://openalex.org/I3018163063"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080651723","display_name":"Patrick J. Leroy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I3018163063","display_name":"St. Elizabeth's Medical Center","ror":"https://ror.org/00cr15z55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3018163063"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patrick J LeRoy","raw_affiliation_strings":["Section of Oncology/Hematology Research, Departments of Medicine, Anatomy and Cellular Biology, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Oncology/Hematology Research, Departments of Medicine, Anatomy and Cellular Biology, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA","institution_ids":["https://openalex.org/I121934306","https://openalex.org/I3018163063"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085025992","display_name":"Pei-shan Zhao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I3018163063","display_name":"St. Elizabeth's Medical Center","ror":"https://ror.org/00cr15z55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3018163063"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pei-shan Zhao","raw_affiliation_strings":["Section of Oncology/Hematology Research, Departments of Medicine, Anatomy and Cellular Biology, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Oncology/Hematology Research, Departments of Medicine, Anatomy and Cellular Biology, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA","institution_ids":["https://openalex.org/I121934306","https://openalex.org/I3018163063"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040256114","display_name":"Steven S. Oh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I3018163063","display_name":"St. Elizabeth's Medical Center","ror":"https://ror.org/00cr15z55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3018163063"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S.Steven Oh","raw_affiliation_strings":["Section of Oncology/Hematology Research, Departments of Medicine, Anatomy and Cellular Biology, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Oncology/Hematology Research, Departments of Medicine, Anatomy and Cellular Biology, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA","institution_ids":["https://openalex.org/I121934306","https://openalex.org/I3018163063"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046912410","display_name":"Athar H. Chishti","orcid":"https://orcid.org/0000-0003-0335-1861","observed_orcids":["https://orcid.org/0000-0003-0335-1861"]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I3018163063","display_name":"St. Elizabeth's Medical Center","ror":"https://ror.org/00cr15z55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3018163063"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Athar H Chishti","raw_affiliation_strings":["Section of Oncology/Hematology Research, Departments of Medicine, Anatomy and Cellular Biology, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Oncology/Hematology Research, Departments of Medicine, Anatomy and Cellular Biology, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA","institution_ids":["https://openalex.org/I121934306","https://openalex.org/I3018163063"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061926545","display_name":"Shih\u2010Chun Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121934306","display_name":"Tufts University","ror":"https://ror.org/05wvpxv85","country_code":"US","type":"education","lineage":["https://openalex.org/I121934306"]},{"id":"https://openalex.org/I3018163063","display_name":"St. Elizabeth's Medical Center","ror":"https://ror.org/00cr15z55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3018163063"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shih-Chun Liu","raw_affiliation_strings":["Section of Oncology/Hematology Research, Departments of Medicine, Anatomy and Cellular Biology, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Oncology/Hematology Research, Departments of Medicine, Anatomy and Cellular Biology, St Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA, USA","institution_ids":["https://openalex.org/I121934306","https://openalex.org/I3018163063"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5087774699"],"corresponding_institution_ids":["https://openalex.org/I121934306","https://openalex.org/I3018163063"],"apc_list":{"value":3460,"currency":"USD","value_usd":3460},"apc_paid":null,"fwci":2.2607,"has_fulltext":false,"cited_by_count":31,"citation_normalized_percentile":{"value":0.87356488,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"110","issue":"2","first_page":"423","last_page":"428"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12286","display_name":"Erythrocyte Function and Pathophysiology","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/plasmodium-falciparum","display_name":"Plasmodium falciparum","score":0.949999988079071},{"id":"https://openalex.org/keywords/pfemp1","display_name":"PfEMP1","score":0.9340000152587891},{"id":"https://openalex.org/keywords/cytoadherence","display_name":"cytoadherence","score":0.8730000257492065},{"id":"https://openalex.org/keywords/erythrocyte-membrane-proteins","display_name":"erythrocyte membrane proteins","score":0.6589999794960022},{"id":"https://openalex.org/keywords/erythrocyte-cytoskeleton","display_name":"erythrocyte cytoskeleton","score":0.878000020980835},{"id":"https://openalex.org/keywords/parasite-virulence","display_name":"parasite virulence","score":0.5699999928474426},{"id":"https://openalex.org/keywords/shear-force","display_name":"shear force","score":0.46299999952316284},{"id":"https://openalex.org/keywords/schizonts","display_name":"schizonts","score":0.503000020980835}],"concepts":[{"id":"https://openalex.org/C2778371730","wikidata":"https://www.wikidata.org/wiki/Q311383","display_name":"Plasmodium falciparum","level":3,"score":0.8464746475219727},{"id":"https://openalex.org/C142669718","wikidata":"https://www.wikidata.org/wiki/Q154626","display_name":"Cytoskeleton","level":3,"score":0.7740767598152161},{"id":"https://openalex.org/C2776589458","wikidata":"https://www.wikidata.org/wiki/Q425149","display_name":"Band 3","level":4,"score":0.7164590954780579},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7062195539474487},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5336335897445679},{"id":"https://openalex.org/C144647389","wikidata":"https://www.wikidata.org/wiki/Q423042","display_name":"Membrane protein","level":3,"score":0.4786492586135864},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4614075720310211},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.452311247587204},{"id":"https://openalex.org/C2776557347","wikidata":"https://www.wikidata.org/wiki/Q37187","display_name":"Red blood cell","level":2,"score":0.4262693524360657},{"id":"https://openalex.org/C125705527","wikidata":"https://www.wikidata.org/wiki/Q185269","display_name":"Actin","level":2,"score":0.41931888461112976},{"id":"https://openalex.org/C84416704","wikidata":"https://www.wikidata.org/wiki/Q188666","display_name":"Adhesion","level":2,"score":0.4101071357727051},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.35188376903533936},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.17766469717025757},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.16901707649230957},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.09132117033004761},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.07843402028083801},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010963","descriptor_name":"Plasmodium falciparum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015800","descriptor_name":"Protozoan Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D055672","descriptor_name":"Static Electricity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0166-6851(00)00281-4","doi":"https://doi.org/10.1016/s0166-6851(00)00281-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0166-6851(00)00281-4","pdf_url":null,"source":{"id":"https://openalex.org/S144099348","display_name":"Molecular and Biochemical Parasitology","issn_l":"0166-6851","issn":["0166-6851","1872-9428"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Biochemical Parasitology","raw_type":"journal-article"},{"id":"pmid:11071296","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11071296","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and biochemical parasitology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3370679286","display_name":null,"funder_award_id":"HL 60961","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G681746002","display_name":null,"funder_award_id":"HL 37462","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7570834074","display_name":"MEMBRANE SKELETON OF NORMAL AND ABNORMAL RED CELLS","funder_award_id":"P01HL037462","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8151599841","display_name":"Role of erythrocyte band 3 in malaria adhesion","funder_award_id":"R01HL060961","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W105433308","https://openalex.org/W206142983","https://openalex.org/W1800815393","https://openalex.org/W1855353753","https://openalex.org/W1966591945","https://openalex.org/W1995725957","https://openalex.org/W2009052964","https://openalex.org/W2009448974","https://openalex.org/W2016779039","https://openalex.org/W2021874649","https://openalex.org/W2029372771","https://openalex.org/W2043873794","https://openalex.org/W2049700891","https://openalex.org/W2082082055","https://openalex.org/W2085541452","https://openalex.org/W2093451052","https://openalex.org/W2146472357","https://openalex.org/W2418509754","https://openalex.org/W4231646317"],"related_works":["https://openalex.org/W2075412398","https://openalex.org/W2094797464","https://openalex.org/W2231638149","https://openalex.org/W2769679296","https://openalex.org/W2029372771","https://openalex.org/W2749945688","https://openalex.org/W2015082048","https://openalex.org/W1996117877","https://openalex.org/W2043873794","https://openalex.org/W2980289092"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
