{"id":"https://openalex.org/W2013335153","doi":"https://doi.org/10.1016/s0171-2985(86)80098-5","title":"Human Pluripotent Hemopoietic Colony Stimulating Factor: Activities on Human and Murine Cells","display_name":"Human Pluripotent Hemopoietic Colony Stimulating Factor: Activities on Human and Murine Cells","publication_year":1986,"publication_date":"1986-09-01","ids":{"openalex":"https://openalex.org/W2013335153","doi":"https://doi.org/10.1016/s0171-2985(86)80098-5","mag":"2013335153","pmid":"https://pubmed.ncbi.nlm.nih.gov/3492429"},"language":"en","primary_location":{"id":"doi:10.1016/s0171-2985(86)80098-5","doi":"https://doi.org/10.1016/s0171-2985(86)80098-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0171-2985(86)80098-5","pdf_url":null,"source":{"id":"https://openalex.org/S164377831","display_name":"Immunobiology","issn_l":"0171-2985","issn":["0171-2985","1878-3279"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunobiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109214234","display_name":"Erich Platzer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"E. Platzer","raw_affiliation_strings":["Institute for Clinical Immunology and Rheumatology, University of Erlangen, Erlangen, Federal Republic of Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Clinical Immunology and Rheumatology, University of Erlangen, Erlangen, Federal Republic of Germany","institution_ids":["https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111529699","display_name":"Sadik Oez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"S. Oez","raw_affiliation_strings":["Institute for Clinical Immunology and Rheumatology, University of Erlangen, Erlangen, Federal Republic of Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Clinical Immunology and Rheumatology, University of Erlangen, Erlangen, Federal Republic of Germany","institution_ids":["https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012976716","display_name":"Karl Welte","orcid":"https://orcid.org/0000-0001-5178-3074","observed_orcids":["https://orcid.org/0000-0001-5178-3074"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K. Welte","raw_affiliation_strings":["Departments for Developmental Hematopoiesis and Molecular Hematology, Memorial Sloan-Kettering Cancer Center, New York, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments for Developmental Hematopoiesis and Molecular Hematology, Memorial Sloan-Kettering Cancer Center, New York, U.S.A","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110237886","display_name":"Andreas Sendler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"A. Sendler","raw_affiliation_strings":["Institute for Clinical Immunology and Rheumatology, University of Erlangen, Erlangen, Federal Republic of Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Clinical Immunology and Rheumatology, University of Erlangen, Erlangen, Federal Republic of Germany","institution_ids":["https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062295987","display_name":"Janice Lynn Gabrilove","orcid":"https://orcid.org/0000-0002-2967-4493","observed_orcids":["https://orcid.org/0000-0002-2967-4493"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.L. Gabrilove","raw_affiliation_strings":["Departments for Developmental Hematopoiesis and Molecular Hematology, Memorial Sloan-Kettering Cancer Center, New York, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments for Developmental Hematopoiesis and Molecular Hematology, Memorial Sloan-Kettering Cancer Center, New York, U.S.A","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052017720","display_name":"R Mertelsmann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. Mertelsmann","raw_affiliation_strings":["Departments for Developmental Hematopoiesis and Molecular Hematology, Memorial Sloan-Kettering Cancer Center, New York, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments for Developmental Hematopoiesis and Molecular Hematology, Memorial Sloan-Kettering Cancer Center, New York, U.S.A","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110863459","display_name":"Malcolm A.S. Moore","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M.A. S. Moore","raw_affiliation_strings":["Departments for Developmental Hematopoiesis and Molecular Hematology, Memorial Sloan-Kettering Cancer Center, New York, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments for Developmental Hematopoiesis and Molecular Hematology, Memorial Sloan-Kettering Cancer Center, New York, U.S.A","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111735774","display_name":"J. R. Kalden","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"J.R. Kalden","raw_affiliation_strings":["Institute for Clinical Immunology and Rheumatology, University of Erlangen, Erlangen, Federal Republic of Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Clinical Immunology and Rheumatology, University of Erlangen, Erlangen, Federal Republic of Germany","institution_ids":["https://openalex.org/I181369854"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2840,"currency":"USD","value_usd":2840},"apc_paid":null,"fwci":2.9207,"has_fulltext":false,"cited_by_count":54,"citation_normalized_percentile":{"value":0.9115498,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"172","issue":"3-5","first_page":"185","last_page":"193"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.8657000064849854,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.8657000064849854,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.06419999897480011,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions","score":0.01730000041425228,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/colony-stimulating-factors","display_name":"colony-stimulating factors","score":0.8149999976158142},{"id":"https://openalex.org/keywords/hematopoietic-progenitor-cells","display_name":"hematopoietic progenitor cells","score":0.7400000095367432},{"id":"https://openalex.org/keywords/cfu-gm","display_name":"CFU-GM","score":0.9850000143051147},{"id":"https://openalex.org/keywords/granulocyte-colony-stimulating-factor","display_name":"granulocyte colony-stimulating factor","score":0.6600000262260437},{"id":"https://openalex.org/keywords/synergistic-action","display_name":"synergistic activity","score":0.4320000112056732},{"id":"https://openalex.org/keywords/neutrophil-cytotoxicity","display_name":"neutrophil cytotoxicity","score":0.8410000205039978},{"id":"https://openalex.org/keywords/antibody-dependent-cellular-cytotoxicity","display_name":"antibody-dependent cellular cytotoxicity","score":0.9909999966621399},{"id":"https://openalex.org/keywords/granulocyte-precursors","display_name":"granulocyte precursors","score":0.8320000171661377},{"id":"https://openalex.org/keywords/mouse-cells","display_name":"mouse cells","score":0.7860000133514404}],"concepts":[{"id":"https://openalex.org/C107459253","wikidata":"https://www.wikidata.org/wiki/Q674925","display_name":"Induced pluripotent stem cell","level":4,"score":0.7911261320114136},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.7031851410865784},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.584755003452301},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.5628934502601624},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.5402981042861938},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5044809579849243},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4742017388343811},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.46054524183273315},{"id":"https://openalex.org/C880424","wikidata":"https://www.wikidata.org/wiki/Q416030","display_name":"Colony-stimulating factor","level":4,"score":0.4555753767490387},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4366884231567383},{"id":"https://openalex.org/C2777983669","wikidata":"https://www.wikidata.org/wiki/Q223143","display_name":"Granulocyte","level":2,"score":0.4231572449207306},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.3414645791053772},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.1460188329219818},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13396969437599182},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000920","descriptor_name":"Antibody-Dependent Cell Cytotoxicity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001854","descriptor_name":"Bone Marrow Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002453","descriptor_name":"Cell Cycle","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003114","descriptor_name":"Colony-Forming Units Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003115","descriptor_name":"Colony-Stimulating Factors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004357","descriptor_name":"Drug Synergism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006133","descriptor_name":"Growth Substances","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D006410","descriptor_name":"Hematopoiesis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008815","descriptor_name":"Mice, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0171-2985(86)80098-5","doi":"https://doi.org/10.1016/s0171-2985(86)80098-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0171-2985(86)80098-5","pdf_url":null,"source":{"id":"https://openalex.org/S164377831","display_name":"Immunobiology","issn_l":"0171-2985","issn":["0171-2985","1878-3279"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunobiology","raw_type":"journal-article"},{"id":"pmid:3492429","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3492429","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunobiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1517056268","https://openalex.org/W1675276494","https://openalex.org/W1963843070","https://openalex.org/W1971869828","https://openalex.org/W1993880501","https://openalex.org/W2068021117","https://openalex.org/W2092368843","https://openalex.org/W2131354945","https://openalex.org/W2152273804","https://openalex.org/W2225117017","https://openalex.org/W2414812974","https://openalex.org/W2419393926"],"related_works":["https://openalex.org/W1993880501","https://openalex.org/W2419393926","https://openalex.org/W2094113478","https://openalex.org/W2109258274","https://openalex.org/W1575954529","https://openalex.org/W7098672586","https://openalex.org/W2068021117","https://openalex.org/W1585358225","https://openalex.org/W2063232385","https://openalex.org/W2056202093"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}