{"id":"https://openalex.org/W2013335145","doi":"https://doi.org/10.1007/s002130050262","title":"Enhancement by flumazenil of dopamine release in the nucleus accumbens of rats repeatedly exposed to diazepam or imidazenil","display_name":"Enhancement by flumazenil of dopamine release in the nucleus accumbens of rats repeatedly exposed to diazepam or imidazenil","publication_year":1997,"publication_date":"1997-05-15","ids":{"openalex":"https://openalex.org/W2013335145","doi":"https://doi.org/10.1007/s002130050262","mag":"2013335145","pmid":"https://pubmed.ncbi.nlm.nih.gov/9181633"},"language":"en","primary_location":{"id":"doi:10.1007/s002130050262","doi":"https://doi.org/10.1007/s002130050262","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s002130050262","pdf_url":null,"source":{"id":"https://openalex.org/S80334769","display_name":"Psychopharmacology","issn_l":"0033-3158","issn":["0033-3158","1432-2072"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychopharmacology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083331235","display_name":"Costantino Motzo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I172446870","display_name":"University of Cagliari","ror":"https://ror.org/003109y17","country_code":"IT","type":"education","lineage":["https://openalex.org/I172446870"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"C. Motzo","raw_affiliation_strings":["Department of Experimental Biology, University of Cagliari, Italy","Department of Experimental Biology, University of Cagliari,Via Palabanda 12, I-09123 Cagliari, Italy Tel: (+39) 70/670559, Fax (+39) 70/660696, IT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Biology, University of Cagliari, Italy","institution_ids":["https://openalex.org/I172446870"]},{"raw_affiliation_string":"Department of Experimental Biology, University of Cagliari,Via Palabanda 12, I-09123 Cagliari, Italy Tel: (+39) 70/670559, Fax (+39) 70/660696, IT","institution_ids":["https://openalex.org/I172446870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109565698","display_name":"Maria Luisa Porceddu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I172446870","display_name":"University of Cagliari","ror":"https://ror.org/003109y17","country_code":"IT","type":"education","lineage":["https://openalex.org/I172446870"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M. L. Porceddu","raw_affiliation_strings":["Department of Experimental Biology, University of Cagliari,Via Palabanda 12, I-09123 Cagliari, Italy Tel: (+39) 70/670559, Fax (+39) 70/660696, IT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Biology, University of Cagliari,Via Palabanda 12, I-09123 Cagliari, Italy Tel: (+39) 70/670559, Fax (+39) 70/660696, IT","institution_ids":["https://openalex.org/I172446870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066081782","display_name":"Laura Dazzi","orcid":"https://orcid.org/0000-0002-7102-0530","observed_orcids":["https://orcid.org/0000-0002-7102-0530"]},"institutions":[{"id":"https://openalex.org/I172446870","display_name":"University of Cagliari","ror":"https://ror.org/003109y17","country_code":"IT","type":"education","lineage":["https://openalex.org/I172446870"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"L. Dazzi","raw_affiliation_strings":["Department of Experimental Biology, University of Cagliari,Via Palabanda 12, I-09123 Cagliari, Italy Tel: (+39) 70/670559, Fax (+39) 70/660696, IT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Biology, University of Cagliari,Via Palabanda 12, I-09123 Cagliari, Italy Tel: (+39) 70/670559, Fax (+39) 70/660696, IT","institution_ids":["https://openalex.org/I172446870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042203237","display_name":"Angela Sanna","orcid":"https://orcid.org/0000-0001-6390-3811","observed_orcids":["https://orcid.org/0000-0001-6390-3811"]},"institutions":[{"id":"https://openalex.org/I172446870","display_name":"University of Cagliari","ror":"https://ror.org/003109y17","country_code":"IT","type":"education","lineage":["https://openalex.org/I172446870"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A. Sanna","raw_affiliation_strings":["Department of Experimental Biology, University of Cagliari,Via Palabanda 12, I-09123 Cagliari, Italy Tel: (+39) 70/670559, Fax (+39) 70/660696, IT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Biology, University of Cagliari,Via Palabanda 12, I-09123 Cagliari, Italy Tel: (+39) 70/670559, Fax (+39) 70/660696, IT","institution_ids":["https://openalex.org/I172446870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028115615","display_name":"Mariangela Serra","orcid":"https://orcid.org/0000-0002-6908-4228","observed_orcids":["https://orcid.org/0000-0002-6908-4228"]},"institutions":[{"id":"https://openalex.org/I172446870","display_name":"University of Cagliari","ror":"https://ror.org/003109y17","country_code":"IT","type":"education","lineage":["https://openalex.org/I172446870"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M. Serra","raw_affiliation_strings":["Department of Experimental Biology, University of Cagliari,Via Palabanda 12, I-09123 Cagliari, Italy Tel: (+39) 70/670559, Fax (+39) 70/660696, IT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Biology, University of Cagliari,Via Palabanda 12, I-09123 Cagliari, Italy Tel: (+39) 70/670559, Fax (+39) 70/660696, IT","institution_ids":["https://openalex.org/I172446870"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090509427","display_name":"Giovanni Biggio","orcid":"https://orcid.org/0000-0003-2333-5535","observed_orcids":["https://orcid.org/0000-0003-2333-5535"]},"institutions":[{"id":"https://openalex.org/I172446870","display_name":"University of Cagliari","ror":"https://ror.org/003109y17","country_code":"IT","type":"education","lineage":["https://openalex.org/I172446870"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G. Biggio","raw_affiliation_strings":["Department of Experimental Biology, University of Cagliari,Via Palabanda 12, I-09123 Cagliari, Italy Tel: (+39) 70/670559, Fax (+39) 70/660696, IT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Biology, University of Cagliari,Via Palabanda 12, I-09123 Cagliari, Italy Tel: (+39) 70/670559, Fax (+39) 70/660696, IT","institution_ids":["https://openalex.org/I172446870"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I172446870"],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":0.5243,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.58128845,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"131","issue":"1","first_page":"34","last_page":"39"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.9678000211715698,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.9678000211715698,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.027300000190734863,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10043","display_name":"Substance Abuse Treatment and Outcomes","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/flumazenil","display_name":"flumazenil","score":0.9789999723434448},{"id":"https://openalex.org/keywords/diazepam","display_name":"diazepam","score":0.8199999928474426},{"id":"https://openalex.org/keywords/benzodiazepine-receptor","display_name":"benzodiazepine receptor","score":0.8130000233650208},{"id":"https://openalex.org/keywords/dopamine-release","display_name":"dopamine release","score":0.7319999933242798},{"id":"https://openalex.org/keywords/nucleus-accumbens","display_name":"nucleus accumbens","score":1.0},{"id":"https://openalex.org/keywords/benzodiazepine-withdrawal","display_name":"benzodiazepine withdrawal","score":0.8450000286102295},{"id":"https://openalex.org/keywords/benzodiazepine-dependence","display_name":"benzodiazepine dependence","score":0.8560000061988831},{"id":"https://openalex.org/keywords/partial-agonists","display_name":"partial agonists","score":0.7319999933242798},{"id":"https://openalex.org/keywords/full-agonists","display_name":"full agonists","score":0.9010000228881836},{"id":"https://openalex.org/keywords/drug-withdrawal-syndrome","display_name":"drug withdrawal syndrome","score":0.335999995470047}],"concepts":[{"id":"https://openalex.org/C2776552330","wikidata":"https://www.wikidata.org/wiki/Q1476178","display_name":"Nucleus accumbens","level":3,"score":0.9342434406280518},{"id":"https://openalex.org/C2778409475","wikidata":"https://www.wikidata.org/wiki/Q421920","display_name":"Flumazenil","level":4,"score":0.7817456722259521},{"id":"https://openalex.org/C2776175493","wikidata":"https://www.wikidata.org/wiki/Q210402","display_name":"Diazepam","level":2,"score":0.7190130949020386},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.6678207516670227},{"id":"https://openalex.org/C2778173252","wikidata":"https://www.wikidata.org/wiki/Q83871","display_name":"Benzodiazepine","level":3,"score":0.6476236581802368},{"id":"https://openalex.org/C137183658","wikidata":"https://www.wikidata.org/wiki/Q461076","display_name":"Dopaminergic","level":3,"score":0.5812274217605591},{"id":"https://openalex.org/C2778938600","wikidata":"https://www.wikidata.org/wiki/Q389934","display_name":"Agonist","level":3,"score":0.5446353554725647},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5124223828315735},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5094619393348694},{"id":"https://openalex.org/C120069818","wikidata":"https://www.wikidata.org/wiki/Q415496","display_name":"Dopamine receptor","level":3,"score":0.46013325452804565},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4558999240398407},{"id":"https://openalex.org/C2778187257","wikidata":"https://www.wikidata.org/wiki/Q464210","display_name":"Basal ganglia","level":3,"score":0.45061129331588745},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.43471673130989075},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.24127739667892456},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23321262001991272},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.14098432660102844}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001569","descriptor_name":"Benzodiazepines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D003975","descriptor_name":"Diazepam","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004357","descriptor_name":"Drug Synergism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005442","descriptor_name":"Flumazenil","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D007093","descriptor_name":"Imidazoles","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009714","descriptor_name":"Nucleus Accumbens","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D009714","descriptor_name":"Nucleus Accumbens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018757","descriptor_name":"GABA Modulators","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/s002130050262","doi":"https://doi.org/10.1007/s002130050262","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s002130050262","pdf_url":null,"source":{"id":"https://openalex.org/S80334769","display_name":"Psychopharmacology","issn_l":"0033-3158","issn":["0033-3158","1432-2072"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychopharmacology","raw_type":"journal-article"},{"id":"pmid:9181633","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9181633","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychopharmacology","raw_type":"Journal Article"},{"id":"pmh:oai:iris.unica.it:11584/106432","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11584/106432","pdf_url":null,"source":{"id":"https://openalex.org/S4377196293","display_name":"UNICA IRIS Institutional Research Information System (University of Cagliari)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I172446870","host_organization_name":"University of Cagliari","host_organization_lineage":["https://openalex.org/I172446870"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.4099999964237213,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2042186726","https://openalex.org/W2562221776","https://openalex.org/W1988918626","https://openalex.org/W7020855972","https://openalex.org/W2089184509","https://openalex.org/W2241843397","https://openalex.org/W2765549027","https://openalex.org/W1979374956","https://openalex.org/W3018559317","https://openalex.org/W2007943279"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}