{"id":"https://openalex.org/W2013292129","doi":"https://doi.org/10.1016/j.vaccine.2009.04.064","title":"Genome flexibility in Neisseria meningitidis","display_name":"Genome flexibility in Neisseria meningitidis","publication_year":2009,"publication_date":"2009-05-28","ids":{"openalex":"https://openalex.org/W2013292129","doi":"https://doi.org/10.1016/j.vaccine.2009.04.064","mag":"2013292129","pmid":"https://pubmed.ncbi.nlm.nih.gov/19477564"},"language":"en","primary_location":{"id":"doi:10.1016/j.vaccine.2009.04.064","doi":"https://doi.org/10.1016/j.vaccine.2009.04.064","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.vaccine.2009.04.064","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0264410X09006185/pdf","source":{"id":"https://openalex.org/S27359860","display_name":"Vaccine","issn_l":"0264-410X","issn":["0264-410X","1873-2518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S0264410X09006185/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036667980","display_name":"Christoph U. Schoen","orcid":"https://orcid.org/0000-0003-2222-1085","observed_orcids":["https://orcid.org/0000-0003-2222-1085"]},"institutions":[{"id":"https://openalex.org/I25974101","display_name":"University of W\u00fcrzburg","ror":"https://ror.org/00fbnyb24","country_code":"DE","type":"education","lineage":["https://openalex.org/I25974101"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Christoph Schoen","raw_affiliation_strings":["Institut f\u00fcr Hygiene und Mikrobiologie, der Universit\u00e4t W\u00fcrzburg, Josef-Schneider-Strasse 2, Bau E1, W\u00fcrzburg 97877, Germany. cschoen@hygiene.uni-wuerzburg.de","Institut f\u00fcr Hygiene und Mikrobiologie, der Universit\u00e4t W\u00fcrzburg, Josef-Schneider-Strasse 2, Bau E1, W\u00fcrzburg 97877, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Hygiene und Mikrobiologie, der Universit\u00e4t W\u00fcrzburg, Josef-Schneider-Strasse 2, Bau E1, W\u00fcrzburg 97877, Germany. cschoen@hygiene.uni-wuerzburg.de","institution_ids":["https://openalex.org/I25974101"]},{"raw_affiliation_string":"Institut f\u00fcr Hygiene und Mikrobiologie, der Universit\u00e4t W\u00fcrzburg, Josef-Schneider-Strasse 2, Bau E1, W\u00fcrzburg 97877, Germany","institution_ids":["https://openalex.org/I25974101"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084925508","display_name":"Herv\u00e9 Tettelin","orcid":"https://orcid.org/0000-0002-0615-3257","observed_orcids":["https://orcid.org/0000-0002-0615-3257"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Herv\u00e9 Tettelin","raw_affiliation_strings":["Institute for Genome Sciences, Department of Microbiology and Immunology, University of Maryland Biopark, 801 West Baltimore Street, Room 629, Baltimore, MD 21201, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Genome Sciences, Department of Microbiology and Immunology, University of Maryland Biopark, 801 West Baltimore Street, Room 629, Baltimore, MD 21201, USA","institution_ids":["https://openalex.org/I126744593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084268602","display_name":"Julian Parkhill","orcid":"https://orcid.org/0000-0002-7069-5958","observed_orcids":["https://orcid.org/0000-0002-7069-5958"]},"institutions":[{"id":"https://openalex.org/I2802476451","display_name":"Wellcome Sanger Institute","ror":"https://ror.org/05cy4wa09","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I2802476451","https://openalex.org/I87048295"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Julian Parkhill","raw_affiliation_strings":["Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK","Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK","institution_ids":["https://openalex.org/I2802476451"]},{"raw_affiliation_string":"Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA UK","institution_ids":["https://openalex.org/I2802476451"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029853341","display_name":"Matthias Frosch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I25974101","display_name":"University of W\u00fcrzburg","ror":"https://ror.org/00fbnyb24","country_code":"DE","type":"education","lineage":["https://openalex.org/I25974101"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Matthias Frosch","raw_affiliation_strings":["Institut f\u00fcr Hygiene und Mikrobiologie, der Universit\u00e4t W\u00fcrzburg, Josef-Schneider-Strasse 2, Bau E1, 97877 W\u00fcrzburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Hygiene und Mikrobiologie, der Universit\u00e4t W\u00fcrzburg, Josef-Schneider-Strasse 2, Bau E1, 97877 W\u00fcrzburg, Germany","institution_ids":["https://openalex.org/I25974101"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5036667980"],"corresponding_institution_ids":["https://openalex.org/I25974101"],"apc_list":{"value":3620,"currency":"USD","value_usd":3620},"apc_paid":{"value":3620,"currency":"USD","value_usd":3620},"fwci":5.7261,"has_fulltext":true,"cited_by_count":63,"citation_normalized_percentile":{"value":0.95521812,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"27","issue":null,"first_page":"B103","last_page":"B111"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10943","display_name":"Escherichia coli research studies","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neisseria-meningitidis","display_name":"Neisseria meningitidis","score":1.0},{"id":"https://openalex.org/keywords/genomic-variation","display_name":"genomic variation","score":0.5509999990463257},{"id":"https://openalex.org/keywords/bacterial-virulence","display_name":"bacterial virulence","score":0.8309999704360962},{"id":"https://openalex.org/keywords/meningitis","display_name":"meningitis","score":0.718999981880188},{"id":"https://openalex.org/keywords/sepsis","display_name":"sepsis","score":0.9169999957084656},{"id":"https://openalex.org/keywords/comparative-genomics","display_name":"comparative genomics","score":0.902999997138977},{"id":"https://openalex.org/keywords/bacterial-evolution","display_name":"bacterial evolution","score":0.675000011920929},{"id":"https://openalex.org/keywords/environmental-adaptation","display_name":"environmental adaptation","score":0.47999998927116394}],"concepts":[{"id":"https://openalex.org/C2778458888","wikidata":"https://www.wikidata.org/wiki/Q154625","display_name":"Neisseria meningitidis","level":3,"score":0.9270728826522827},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.7816670536994934},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7451673746109009},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.6758132576942444},{"id":"https://openalex.org/C105176652","wikidata":"https://www.wikidata.org/wiki/Q1147112","display_name":"Comparative genomics","level":5,"score":0.6120675802230835},{"id":"https://openalex.org/C2777954195","wikidata":"https://www.wikidata.org/wiki/Q132209","display_name":"Neisseria","level":3,"score":0.5561397075653076},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.5550084710121155},{"id":"https://openalex.org/C139807058","wikidata":"https://www.wikidata.org/wiki/Q352374","display_name":"Adaptation (eye)","level":2,"score":0.4961274564266205},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.48506489396095276},{"id":"https://openalex.org/C2776645655","wikidata":"https://www.wikidata.org/wiki/Q890785","display_name":"Meningococcal disease","level":4,"score":0.44729360938072205},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4159683883190155},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.273751825094223},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.23050320148468018},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000220","descriptor_name":"Adaptation, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000220","descriptor_name":"Adaptation, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000220","descriptor_name":"Adaptation, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009345","descriptor_name":"Neisseria meningitidis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009345","descriptor_name":"Neisseria meningitidis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009345","descriptor_name":"Neisseria meningitidis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011995","descriptor_name":"Recombination, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011995","descriptor_name":"Recombination, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011995","descriptor_name":"Recombination, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.vaccine.2009.04.064","doi":"https://doi.org/10.1016/j.vaccine.2009.04.064","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.vaccine.2009.04.064","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0264410X09006185/pdf","source":{"id":"https://openalex.org/S27359860","display_name":"Vaccine","issn_l":"0264-410X","issn":["0264-410X","1873-2518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"journal-article"},{"id":"pmid:19477564","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19477564","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2885320","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3898611","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3898611","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3898611","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Vaccine","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.vaccine.2009.04.064","doi":"https://doi.org/10.1016/j.vaccine.2009.04.064","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.vaccine.2009.04.064","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0264410X09006185/pdf","source":{"id":"https://openalex.org/S27359860","display_name":"Vaccine","issn_l":"0264-410X","issn":["0264-410X","1873-2518"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-200","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vaccine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.6600000262260437,"id":"https://metadata.un.org/sdg/15","display_name":"Life on land"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321114","display_name":"Bundesministerium f\u00fcr Bildung und Forschung","ror":"https://ror.org/04pz7b180"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2013292129.pdf","grobid_xml":"https://content.openalex.org/works/W2013292129.grobid-xml"},"referenced_works_count":75,"referenced_works":["https://openalex.org/W575101333","https://openalex.org/W1497945502","https://openalex.org/W1522770837","https://openalex.org/W1540502358","https://openalex.org/W1804726954","https://openalex.org/W1968146772","https://openalex.org/W1968943198","https://openalex.org/W1971403296","https://openalex.org/W1972740086","https://openalex.org/W1986897865","https://openalex.org/W1990321397","https://openalex.org/W1990453950","https://openalex.org/W1991330646","https://openalex.org/W1993584992","https://openalex.org/W1994103748","https://openalex.org/W1995703715","https://openalex.org/W1996616626","https://openalex.org/W1998743067","https://openalex.org/W2004753931","https://openalex.org/W2006205474","https://openalex.org/W2012506967","https://openalex.org/W2024895709","https://openalex.org/W2025337114","https://openalex.org/W2028546667","https://openalex.org/W2029277223","https://openalex.org/W2029462694","https://openalex.org/W2031643774","https://openalex.org/W2032801248","https://openalex.org/W2044510197","https://openalex.org/W2044833949","https://openalex.org/W2045162565","https://openalex.org/W2054896894","https://openalex.org/W2057342234","https://openalex.org/W2068225247","https://openalex.org/W2080724113","https://openalex.org/W2080885816","https://openalex.org/W2082919450","https://openalex.org/W2085296777","https://openalex.org/W2090700204","https://openalex.org/W2093610003","https://openalex.org/W2094044277","https://openalex.org/W2100152398","https://openalex.org/W2100478698","https://openalex.org/W2102920659","https://openalex.org/W2111553955","https://openalex.org/W2112234668","https://openalex.org/W2112882649","https://openalex.org/W2112927445","https://openalex.org/W2114770490","https://openalex.org/W2115523105","https://openalex.org/W2124672930","https://openalex.org/W2127335580","https://openalex.org/W2128161048","https://openalex.org/W2131459995","https://openalex.org/W2134519547","https://openalex.org/W2137659264","https://openalex.org/W2138450775","https://openalex.org/W2145694918","https://openalex.org/W2148435514","https://openalex.org/W2150550043","https://openalex.org/W2151371624","https://openalex.org/W2153887780","https://openalex.org/W2155507398","https://openalex.org/W2155534524","https://openalex.org/W2157931451","https://openalex.org/W2158895096","https://openalex.org/W2160423401","https://openalex.org/W2161247547","https://openalex.org/W2162423297","https://openalex.org/W2163255170","https://openalex.org/W2172260003","https://openalex.org/W4211043921","https://openalex.org/W4211090384","https://openalex.org/W4236165064","https://openalex.org/W4240238624"],"related_works":["https://openalex.org/W1957800381","https://openalex.org/W2003004797","https://openalex.org/W2163631167","https://openalex.org/W2891721133","https://openalex.org/W2018660896","https://openalex.org/W2408300477","https://openalex.org/W4230979920","https://openalex.org/W2049463023","https://openalex.org/W4387115080","https://openalex.org/W2021588001"],"abstract_inverted_index":{"Neisseria":[0],"meningitidis":[1,54,89],"usually":[2],"lives":[3],"as":[4,24,91,100],"a":[5,57,66,92],"commensal":[6],"bacterium":[7],"in":[8],"the":[9,47,80],"upper":[10],"airways":[11],"of":[12,68,82],"humans.":[13],"However,":[14],"occasionally":[15],"some":[16],"strains":[17,42],"can":[18],"also":[19,64,77],"cause":[20],"life-threatening":[21],"diseases":[22],"such":[23],"sepsis":[25],"and":[26,40,51,105],"bacterial":[27],"meningitis.":[28],"Comparative":[29,61],"genomics":[30],"demonstrates":[31],"that":[32,52,96],"only":[33],"very":[34,58],"subtle":[35],"genetic":[36,69],"differences":[37,50],"between":[38],"carriage":[39],"disease":[41],"might":[43,78],"be":[44],"responsible":[45],"for":[46,94],"observed":[48],"virulence":[49,81],"N.":[53,88],"is,":[55],"evolutionarily,":[56],"recent":[59],"species.":[60],"genome":[62,98],"sequencing":[63],"revealed":[65],"panoply":[67],"mechanisms":[70],"underlying":[71],"its":[72],"enormous":[73],"genomic":[74],"flexibility":[75],"which":[76],"affect":[79],"particular":[83],"strains.":[84],"From":[85],"these":[86],"studies,":[87],"emerges":[90],"paradigm":[93],"organisms":[95],"use":[97],"variability":[99],"an":[101],"adaptation":[102],"to":[103],"changing":[104],"thus":[106],"challenging":[107],"environments.":[108]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":5},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}