{"id":"https://openalex.org/W2013222806","doi":"https://doi.org/10.1083/jcb.82.2.347","title":"Changing patterns of plasma membrane-associated filaments during the initial phases of polymorphonuclear leukocyte adherence.","display_name":"Changing patterns of plasma membrane-associated filaments during the initial phases of polymorphonuclear leukocyte adherence.","publication_year":1979,"publication_date":"1979-08-01","ids":{"openalex":"https://openalex.org/W2013222806","doi":"https://doi.org/10.1083/jcb.82.2.347","mag":"2013222806","pmid":"https://pubmed.ncbi.nlm.nih.gov/383726","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2110465"},"language":"en","primary_location":{"id":"doi:10.1083/jcb.82.2.347","doi":"https://doi.org/10.1083/jcb.82.2.347","is_oa":false,"landing_page_url":"https://doi.org/10.1083/jcb.82.2.347","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of cell biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2110465","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111975892","display_name":"Janet K. Boyles","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Boyles","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5112156938","display_name":"Dorothy Ford Bainton","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D F Bainton","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.8578,"has_fulltext":false,"cited_by_count":116,"citation_normalized_percentile":{"value":0.94038294,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"82","issue":"2","first_page":"347","last_page":"368"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.01269999984651804,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11650","display_name":"Skin and Cellular Biology Research","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polymorphonuclear-leukocytes","display_name":"polymorphonuclear leukocytes","score":0.9760000109672546},{"id":"https://openalex.org/keywords/neutrophil-adhesion","display_name":"neutrophil adhesion","score":0.7870000004768372},{"id":"https://openalex.org/keywords/actin-filaments","display_name":"F-actin","score":0.7689999938011169},{"id":"https://openalex.org/keywords/lamellipodia","display_name":"lamellipodia","score":0.972000002861023},{"id":"https://openalex.org/keywords/cell-spreading","display_name":"cell spreading","score":0.8159999847412109},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.3779999911785126},{"id":"https://openalex.org/keywords/myosin","display_name":"myosin","score":0.6800000071525574},{"id":"https://openalex.org/keywords/actin-cytoskeleton","display_name":"actin cytoskeleton","score":0.6539999842643738},{"id":"https://openalex.org/keywords/cell-substrate-adhesion","display_name":"cell-substrate adhesion","score":0.6190000176429749},{"id":"https://openalex.org/keywords/plasma-membrane-ultrastructure","display_name":"plasma membrane ultrastructure","score":0.6330000162124634}],"concepts":[{"id":"https://openalex.org/C109185818","wikidata":"https://www.wikidata.org/wiki/Q3092607","display_name":"Lamellipodium","level":4,"score":0.8573845624923706},{"id":"https://openalex.org/C14228908","wikidata":"https://www.wikidata.org/wiki/Q2920483","display_name":"Protein filament","level":2,"score":0.8483462929725647},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.7449460029602051},{"id":"https://openalex.org/C189040839","wikidata":"https://www.wikidata.org/wiki/Q329638","display_name":"Microfilament","level":4,"score":0.6876082420349121},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.6683331727981567},{"id":"https://openalex.org/C87555872","wikidata":"https://www.wikidata.org/wiki/Q3141316","display_name":"Ultrastructure","level":2,"score":0.607450544834137},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5820322036743164},{"id":"https://openalex.org/C142669718","wikidata":"https://www.wikidata.org/wiki/Q154626","display_name":"Cytoskeleton","level":3,"score":0.5740870237350464},{"id":"https://openalex.org/C6997183","wikidata":"https://www.wikidata.org/wiki/Q271727","display_name":"Myosin","level":2,"score":0.5513274669647217},{"id":"https://openalex.org/C125705527","wikidata":"https://www.wikidata.org/wiki/Q185269","display_name":"Actin","level":2,"score":0.514460563659668},{"id":"https://openalex.org/C78383274","wikidata":"https://www.wikidata.org/wiki/Q421987","display_name":"Intermediate filament","level":4,"score":0.4794398844242096},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.33320143818855286},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3255161643028259},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.29651975631713867},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.240647554397583},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08901318907737732}],"mesh":[{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003599","descriptor_name":"Cytoskeleton","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":true},{"descriptor_ui":"D006652","descriptor_name":"Histological Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008855","descriptor_name":"Microscopy, Electron, Scanning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D011554","descriptor_name":"Pseudopodia","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1083/jcb.82.2.347","doi":"https://doi.org/10.1083/jcb.82.2.347","is_oa":false,"landing_page_url":"https://doi.org/10.1083/jcb.82.2.347","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of cell biology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2110465","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2110465","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Cell Biol","raw_type":"Text"},{"id":"pmid:383726","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/383726","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of cell biology","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.280.4760","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.280.4760","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/5a/b2/J_Cell_Biol_1979_Aug_1_82(2)_347-368.tar.gz","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2110465","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2110465","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Cell Biol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W1516263041","https://openalex.org/W1526581318","https://openalex.org/W1534412090","https://openalex.org/W1559994288","https://openalex.org/W1971407845","https://openalex.org/W1977528793","https://openalex.org/W1984322384","https://openalex.org/W1988613008","https://openalex.org/W1991763451","https://openalex.org/W1993274691","https://openalex.org/W2007849749","https://openalex.org/W2015989618","https://openalex.org/W2023265740","https://openalex.org/W2031798346","https://openalex.org/W2038084803","https://openalex.org/W2044385169","https://openalex.org/W2044487480","https://openalex.org/W2045014157","https://openalex.org/W2047176385","https://openalex.org/W2058206821","https://openalex.org/W2058442820","https://openalex.org/W2061651602","https://openalex.org/W2062099855","https://openalex.org/W2074955064","https://openalex.org/W2076307165","https://openalex.org/W2090821047","https://openalex.org/W2093203659","https://openalex.org/W2109006351","https://openalex.org/W2109618118","https://openalex.org/W2116403121","https://openalex.org/W2127586684","https://openalex.org/W2130747320","https://openalex.org/W2135630126","https://openalex.org/W2160971658","https://openalex.org/W2336456478","https://openalex.org/W2400688014"],"related_works":["https://openalex.org/W7095989028","https://openalex.org/W2883017068","https://openalex.org/W2889445804","https://openalex.org/W95361310","https://openalex.org/W1995985615","https://openalex.org/W2049368574","https://openalex.org/W2414434411","https://openalex.org/W2056602261","https://openalex.org/W2235702037","https://openalex.org/W2055600721"],"abstract_inverted_index":{"By":[0,184],"utilizing":[1],"a":[2,117,127,145],"combination":[3],"of":[4,23,40,55,100,106,112,121,147,158,197,204,225],"several":[5],"ultrastructural":[6],"techniques,":[7],"we":[8,49],"have":[9],"been":[10],"able":[11],"to":[12,114],"demonstrate":[13],"differences":[14],"in":[15,137,177,208],"filament":[16,129,206],"organization":[17,224],"on":[18,222],"the":[19,32,37,52,97,115,155,159,164,171,180,190,195,223,231],"adherent":[20,68,161],"plasma":[21,232],"membranes":[22,69,103],"spreading":[24],"and":[25,59,73,90,124,149,175],"mobile":[26],"PMN":[27,102,191],"as":[28,30,189],"well":[29],"within":[31,109],"extending":[33,142],"lamellipodia.":[34],"To":[35],"follow":[36],"subplasmalemmal":[38,128],"filaments":[39,212],"this":[41,167],"small":[42],"amoeboid":[43,198],"cell":[44],"during":[45,234],"these":[46],"kinetic":[47],"events,":[48],"sheared":[50],"off":[51],"upper":[53],"portions":[54],"cells":[56,81],"onto":[57],"glass":[58],"carbon":[60],"surfaces":[61],"for":[62,75],"30":[63,110],"s--5":[64],"min.":[65,183],"The":[66],"exposed":[67],"were":[70,82],"immediately":[71],"fixed":[72],"processed":[74],"high-resolution":[76],"SEM":[77],"or":[78,134],"TEM.":[79],"Whole":[80],"also":[83],"examined":[84],"by":[85,95,140],"phase":[86],"contrast":[87],"microscopy,":[88],"SEM,":[89,96],"oriented":[91],"thin":[92],"sections.":[93],"Observed":[94],"inner":[98],"surface":[99],"nonadherent":[101],"is":[104],"free":[105],"filaments,":[107],"but":[108],"s":[111],"attachment":[113],"substrate":[116],"three-dimensional,":[118],"interlocking":[119],"network":[120],"globular":[122],"projections":[123],"radiating":[125],"microfilaments--i.e.,":[126],"complex--is":[130],"consistently":[131],"demonstrable":[132],"(with":[133],"without":[135],"postfixation":[136],"OsO4).":[138],"Seen":[139],"TEM,":[141],"lamellipodia":[143],"contain":[144],"felt":[146],"filamentous":[148],"finely":[150],"granular":[151],"material,":[152],"distinct":[153],"from":[154],"golbule/filament":[156],"complex":[157,169],"adjacent":[160],"membrane.":[162],"In":[163],"spread":[165],"cell,":[166],"golbule-filament":[168],"covers":[170],"entire":[172],"lower":[173],"membrane":[174,233],"increases":[176],"filament-density":[178],"over":[179],"next":[181],"2--3":[182],"3--5":[185],"min":[186],"after":[187],"plating,":[188],"rounds":[192],"up":[193],"before":[194],"initiation":[196],"movements,":[199],"another":[200],"pattern":[201],"emerges--circumferential":[202],"bands":[203],"anastomosing":[205],"bundles":[207],"which":[209],"thick,":[210],"short":[211],"resembling":[213],"myosin":[214],"are":[215],"found.":[216],"This":[217],"work":[218],"provides":[219],"structural":[220],"evidence":[221],"polymerized":[226],"contractile":[227],"elements":[228],"associated":[229],"with":[230],"cellular":[235],"adherence.":[236]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}