{"id":"https://openalex.org/W2013204019","doi":"https://doi.org/10.3945/ajcn.2008.26404","title":"A trial of B vitamins and cognitive function among women at high risk of cardiovascular disease","display_name":"A trial of B vitamins and cognitive function among women at high risk of cardiovascular disease","publication_year":2008,"publication_date":"2008-12-01","ids":{"openalex":"https://openalex.org/W2013204019","doi":"https://doi.org/10.3945/ajcn.2008.26404","mag":"2013204019","pmid":"https://pubmed.ncbi.nlm.nih.gov/19064521","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3470481"},"language":"en","primary_location":{"id":"doi:10.3945/ajcn.2008.26404","doi":"https://doi.org/10.3945/ajcn.2008.26404","is_oa":true,"landing_page_url":"https://doi.org/10.3945/ajcn.2008.26404","pdf_url":null,"source":{"id":"https://openalex.org/S71285955","display_name":"American Journal of Clinical Nutrition","issn_l":"0002-9165","issn":["0002-9165","1938-3207"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Clinical Nutrition","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.3945/ajcn.2008.26404","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014137846","display_name":"Jae Hee Kang","orcid":"https://orcid.org/0000-0003-4812-0557","observed_orcids":["https://orcid.org/0000-0003-4812-0557"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jae Hee Kang","raw_affiliation_strings":["Channing Laboratory, Boston, MA 02115, USA. nhjhk@channing.harvard.edu","From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA","the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Channing Laboratory, Boston, MA 02115, USA. nhjhk@channing.harvard.edu","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084857746","display_name":"Nancy R. Cook","orcid":"https://orcid.org/0000-0002-9705-0842","observed_orcids":["https://orcid.org/0000-0002-9705-0842"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy Cook","raw_affiliation_strings":["From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; and the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)","From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA","the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; and the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049411008","display_name":"JoAnn Elisabeth Manson","orcid":"https://orcid.org/0000-0002-9426-7595","observed_orcids":["https://orcid.org/0000-0002-9426-7595"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"JoAnn Manson","raw_affiliation_strings":["From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; and the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)","From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA","the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; and the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090744975","display_name":"Julie E. Buring","orcid":"https://orcid.org/0000-0003-2648-8692","observed_orcids":["https://orcid.org/0000-0003-2648-8692"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julie E Buring","raw_affiliation_strings":["From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; and the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)","From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA","the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; and the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045787796","display_name":"Christine M. Albert","orcid":"https://orcid.org/0000-0002-2081-1121","observed_orcids":["https://orcid.org/0000-0002-2081-1121"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christine M Albert","raw_affiliation_strings":["From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; and the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)","From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA","the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; and the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088908376","display_name":"Francine Grodstein","orcid":"https://orcid.org/0000-0002-2699-7051","observed_orcids":["https://orcid.org/0000-0002-2699-7051"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Francine Grodstein","raw_affiliation_strings":["From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; and the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)","From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA","the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; and the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"From the Channing Laboratory (JHK, JM, CMA, and FG), the Cardiovascular Division (CMA), and the Division of Preventive Medicine (NC, JM, and JEB), Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"the Department of Epidemiology, Harvard School of Public Health, Boston, MA (JM, JEB, and FG)","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5014137846"],"corresponding_institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"],"apc_list":{"value":5200,"currency":"USD","value_usd":5200},"apc_paid":null,"fwci":8.2447,"has_fulltext":false,"cited_by_count":115,"citation_normalized_percentile":{"value":0.97816253,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"88","issue":"6","first_page":"1602","last_page":"1610"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vitamin-b-supplementation","display_name":"vitamin B supplementation","score":0.8539999723434448},{"id":"https://openalex.org/keywords/folic-acid","display_name":"folic acid","score":0.9620000123977661},{"id":"https://openalex.org/keywords/vitamin-b12","display_name":"vitamin B12","score":0.949999988079071},{"id":"https://openalex.org/keywords/vitamin-b6","display_name":"vitamin B6","score":1.0},{"id":"https://openalex.org/keywords/cognitive-decline","display_name":"cognitive decline","score":0.8349999785423279},{"id":"https://openalex.org/keywords/cognitive-function","display_name":"cognitive function","score":0.6869999766349792},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.7459999918937683},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.8679999709129333},{"id":"https://openalex.org/keywords/older-women","display_name":"older women","score":0.7110000252723694},{"id":"https://openalex.org/keywords/homocysteine","display_name":"homocysteine","score":0.9210000038146973},{"id":"https://openalex.org/keywords/verbal-memory","display_name":"verbal memory","score":0.7279999852180481},{"id":"https://openalex.org/keywords/semantic-fluency","display_name":"semantic fluency","score":0.953000009059906}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7044310569763184},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.6453213691711426},{"id":"https://openalex.org/C3020471959","wikidata":"https://www.wikidata.org/wiki/Q183206","display_name":"B vitamins","level":2,"score":0.5738067030906677},{"id":"https://openalex.org/C2776940978","wikidata":"https://www.wikidata.org/wiki/Q34956","display_name":"Vitamin","level":2,"score":0.5377912521362305},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.5082413554191589},{"id":"https://openalex.org/C2777090595","wikidata":"https://www.wikidata.org/wiki/Q192466","display_name":"Homocysteine","level":2,"score":0.4777485728263855},{"id":"https://openalex.org/C2984863031","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Cognitive decline","level":4,"score":0.47209829092025757},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.45865485072135925},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.42701634764671326},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.3408733606338501},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.309781551361084},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.18552443385124207},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.12851399183273315},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D003071","descriptor_name":"Cognition","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005492","descriptor_name":"Folic Acid","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006710","descriptor_name":"Homocysteine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011594","descriptor_name":"Psychometrics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014803","descriptor_name":"Vitamin B Complex","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D014805","descriptor_name":"Vitamin B 12","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D016009","descriptor_name":"Chi-Square Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018709","descriptor_name":"Statistics, Nonparametric","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019587","descriptor_name":"Dietary Supplements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020138","descriptor_name":"Hyperhomocysteinemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D025101","descriptor_name":"Vitamin B 6","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3945/ajcn.2008.26404","doi":"https://doi.org/10.3945/ajcn.2008.26404","is_oa":true,"landing_page_url":"https://doi.org/10.3945/ajcn.2008.26404","pdf_url":null,"source":{"id":"https://openalex.org/S71285955","display_name":"American Journal of Clinical Nutrition","issn_l":"0002-9165","issn":["0002-9165","1938-3207"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Clinical Nutrition","raw_type":"journal-article"},{"id":"pmid:19064521","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19064521","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of clinical nutrition","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3470481","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3470481","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Am J Clin Nutr","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3945/ajcn.2008.26404","doi":"https://doi.org/10.3945/ajcn.2008.26404","is_oa":true,"landing_page_url":"https://doi.org/10.3945/ajcn.2008.26404","pdf_url":null,"source":{"id":"https://openalex.org/S71285955","display_name":"American Journal of Clinical Nutrition","issn_l":"0002-9165","issn":["0002-9165","1938-3207"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Clinical Nutrition","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1915527054","display_name":"Trials of Prevention of Cognitive Decline in Women","funder_award_id":"R01AG015933","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G7494425046","display_name":"Trial of Antioxidant Therapy of CVD in Women","funder_award_id":"R01HL046959","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7883148442","display_name":"INTRAUTERINE ELECTRODE ARRAY FOR DETERMINATION OF FHR","funder_award_id":"R43HL047959","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W254912689","https://openalex.org/W1492075988","https://openalex.org/W1512343954","https://openalex.org/W1556008598","https://openalex.org/W1837131274","https://openalex.org/W1945836171","https://openalex.org/W1966493435","https://openalex.org/W1968517325","https://openalex.org/W1984270090","https://openalex.org/W1988332892","https://openalex.org/W1995781460","https://openalex.org/W1996233154","https://openalex.org/W2005207559","https://openalex.org/W2031093055","https://openalex.org/W2051413962","https://openalex.org/W2064912482","https://openalex.org/W2064963539","https://openalex.org/W2083019740","https://openalex.org/W2093247513","https://openalex.org/W2099614709","https://openalex.org/W2103825558","https://openalex.org/W2108581685","https://openalex.org/W2109544293","https://openalex.org/W2109938394","https://openalex.org/W2115135910","https://openalex.org/W2123652060","https://openalex.org/W2126889148","https://openalex.org/W2128216834","https://openalex.org/W2135182133","https://openalex.org/W2136057401","https://openalex.org/W2143058766","https://openalex.org/W2144435655","https://openalex.org/W2148917936","https://openalex.org/W2153415741","https://openalex.org/W2156925579","https://openalex.org/W2158766477","https://openalex.org/W2160354131","https://openalex.org/W2183383894","https://openalex.org/W2412856690","https://openalex.org/W2605006141","https://openalex.org/W2970384085","https://openalex.org/W4249034646"],"related_works":["https://openalex.org/W2580137834","https://openalex.org/W2016862466","https://openalex.org/W2133052971","https://openalex.org/W4327976323","https://openalex.org/W2066941024","https://openalex.org/W2538258112","https://openalex.org/W2043410161","https://openalex.org/W2034213812","https://openalex.org/W4236502527","https://openalex.org/W2138622161"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":13},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":12}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}