{"id":"https://openalex.org/W2013177380","doi":"https://doi.org/10.1097/00007890-200111150-00005","title":"OVEREXPRESSION OF HEME OXYGENASE PROTECTS RENAL TUBULAR CELLS AGAINST COLD STORAGE INJURY: Studies Using Hemin Induction and HO-1 Gene Transfer","display_name":"OVEREXPRESSION OF HEME OXYGENASE PROTECTS RENAL TUBULAR CELLS AGAINST COLD STORAGE INJURY: Studies Using Hemin Induction and HO-1 Gene Transfer","publication_year":2001,"publication_date":"2001-11-01","ids":{"openalex":"https://openalex.org/W2013177380","doi":"https://doi.org/10.1097/00007890-200111150-00005","mag":"2013177380","pmid":"https://pubmed.ncbi.nlm.nih.gov/11707736"},"language":"en","primary_location":{"id":"doi:10.1097/00007890-200111150-00005","doi":"https://doi.org/10.1097/00007890-200111150-00005","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00007890-200111150-00005","pdf_url":null,"source":{"id":"https://openalex.org/S11564597","display_name":"Transplantation","issn_l":"0041-1337","issn":["0041-1337","1534-6080"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054698030","display_name":"Ameen Abdulla Salahudeen","orcid":"https://orcid.org/0000-0001-9037-3481","observed_orcids":["https://orcid.org/0000-0001-9037-3481"]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ameen A. Salahudeen","raw_affiliation_strings":["Department of Medicine, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216-4505, USA","Department Medicine, University of Mississippi Medical Center, Jackson, Mississippi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216-4505, USA","institution_ids":["https://openalex.org/I29606459"]},{"raw_affiliation_string":"Department Medicine, University of Mississippi Medical Center, Jackson, Mississippi","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111974603","display_name":"John K. Jenkins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John K. Jenkins","raw_affiliation_strings":["Department Medicine, University of Mississippi Medical Center, Jackson, Mississippi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department Medicine, University of Mississippi Medical Center, Jackson, Mississippi","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108493115","display_name":"Hong Mei Huang","orcid":"https://orcid.org/0009-0002-2448-169X","observed_orcids":["https://orcid.org/0009-0002-2448-169X"]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hong Huang","raw_affiliation_strings":["Department Medicine, University of Mississippi Medical Center, Jackson, Mississippi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department Medicine, University of Mississippi Medical Center, Jackson, Mississippi","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108413306","display_name":"Kenneth Ndebele","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth Ndebele","raw_affiliation_strings":["Department Medicine, University of Mississippi Medical Center, Jackson, Mississippi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department Medicine, University of Mississippi Medical Center, Jackson, Mississippi","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054698030","display_name":"Ameen Abdulla Salahudeen","orcid":"https://orcid.org/0000-0001-9037-3481","observed_orcids":["https://orcid.org/0000-0001-9037-3481"]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Abdulla K. Salahudeen","raw_affiliation_strings":["Department of Medicine, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216-4505, USA","Abdulla K. Salahudeen, MD, FRCP, Associate Professor of Medicine, Renal Division, Department of Medicine, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216-4505. E-mail","Department Medicine, University of Mississippi Medical Center, Jackson, Mississippi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216-4505, USA","institution_ids":["https://openalex.org/I29606459"]},{"raw_affiliation_string":"Abdulla K. Salahudeen, MD, FRCP, Associate Professor of Medicine, Renal Division, Department of Medicine, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216-4505. E-mail","institution_ids":["https://openalex.org/I29606459"]},{"raw_affiliation_string":"Department Medicine, University of Mississippi Medical Center, Jackson, Mississippi","institution_ids":["https://openalex.org/I29606459"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5054698030"],"corresponding_institution_ids":["https://openalex.org/I29606459"],"apc_list":null,"apc_paid":null,"fwci":1.2502,"has_fulltext":false,"cited_by_count":46,"citation_normalized_percentile":{"value":0.76629745,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"72","issue":"9","first_page":"1498","last_page":"1504"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11848","display_name":"Heme Oxygenase-1 and Carbon Monoxide","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11848","display_name":"Heme Oxygenase-1 and Carbon Monoxide","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10999","display_name":"Organ Transplantation Techniques and Outcomes","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12094","display_name":"Hemoglobin structure and function","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heme-oxygenase-1","display_name":"heme oxygenase-1","score":1.0},{"id":"https://openalex.org/keywords/cold-storage-injury","display_name":"cold storage injury","score":0.902999997138977},{"id":"https://openalex.org/keywords/renal-proximal-tubular-epithelial-cells","display_name":"renal proximal tubular epithelial cells","score":0.9760000109672546},{"id":"https://openalex.org/keywords/hemin","display_name":"hemin","score":0.8069999814033508},{"id":"https://openalex.org/keywords/cytoprotection","display_name":"cytoprotection","score":0.8510000109672546},{"id":"https://openalex.org/keywords/iron-release","display_name":"iron release","score":0.7310000061988831},{"id":"https://openalex.org/keywords/ferritin","display_name":"ferritin","score":0.8980000019073486},{"id":"https://openalex.org/keywords/deferoxamine","display_name":"deferoxamine","score":0.8309999704360962},{"id":"https://openalex.org/keywords/organ-preservation","display_name":"organ preservation","score":0.4339999854564667},{"id":"https://openalex.org/keywords/kidney-transplantation","display_name":"kidney transplantation","score":0.7179999947547913},{"id":"https://openalex.org/keywords/transfection","display_name":"transfection","score":0.5789999961853027}],"concepts":[{"id":"https://openalex.org/C2777723881","wikidata":"https://www.wikidata.org/wiki/Q107315604","display_name":"Hemin","level":4,"score":0.9655753374099731},{"id":"https://openalex.org/C2780967304","wikidata":"https://www.wikidata.org/wiki/Q246156","display_name":"Cytoprotection","level":3,"score":0.9372211694717407},{"id":"https://openalex.org/C2779219270","wikidata":"https://www.wikidata.org/wiki/Q419972","display_name":"Heme oxygenase","level":4,"score":0.8471171259880066},{"id":"https://openalex.org/C2988529969","wikidata":"https://www.wikidata.org/wiki/Q5142478","display_name":"Cold storage","level":2,"score":0.6758918762207031},{"id":"https://openalex.org/C2778319317","wikidata":"https://www.wikidata.org/wiki/Q22327449","display_name":"Ferritin","level":2,"score":0.6638553738594055},{"id":"https://openalex.org/C2776217839","wikidata":"https://www.wikidata.org/wiki/Q189621","display_name":"Heme","level":3,"score":0.6137509942054749},{"id":"https://openalex.org/C2776672577","wikidata":"https://www.wikidata.org/wiki/Q419618","display_name":"Deferoxamine","level":2,"score":0.6121339797973633},{"id":"https://openalex.org/C54009773","wikidata":"https://www.wikidata.org/wiki/Q1429031","display_name":"Transfection","level":3,"score":0.5732797384262085},{"id":"https://openalex.org/C2225953","wikidata":"https://www.wikidata.org/wiki/Q1661899","display_name":"Inducer","level":3,"score":0.5206422209739685},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4803929924964905},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.4496699273586273},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.36340638995170593},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.32745909690856934},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30933576822280884},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.3006439208984375},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.19939884543418884},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.14576658606529236},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C144027150","wikidata":"https://www.wikidata.org/wiki/Q48803","display_name":"Horticulture","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003080","descriptor_name":"Cold Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003676","descriptor_name":"Deferoxamine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004790","descriptor_name":"Enzyme Induction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005293","descriptor_name":"Ferritins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D006419","descriptor_name":"Heme Oxygenase (Decyclizing)","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D006419","descriptor_name":"Heme Oxygenase (Decyclizing)","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006427","descriptor_name":"Hemin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007687","descriptor_name":"Kidney Tubules, Proximal","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D007687","descriptor_name":"Kidney Tubules, Proximal","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007687","descriptor_name":"Kidney Tubules, Proximal","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007770","descriptor_name":"L-Lactate Dehydrogenase","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014021","descriptor_name":"Tissue Preservation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014176","descriptor_name":"Protein Biosynthesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015971","descriptor_name":"Gene Expression Regulation, Enzymologic","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D051547","descriptor_name":"Heme Oxygenase-1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/00007890-200111150-00005","doi":"https://doi.org/10.1097/00007890-200111150-00005","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00007890-200111150-00005","pdf_url":null,"source":{"id":"https://openalex.org/S11564597","display_name":"Transplantation","issn_l":"0041-1337","issn":["0041-1337","1534-6080"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation","raw_type":"journal-article"},{"id":"pmid:11707736","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11707736","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G464395340","display_name":null,"funder_award_id":"R01 DK-56835-01","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G6140810628","display_name":null,"funder_award_id":"K-08-01935","funder_id":"https://openalex.org/F4320332505","funder_display_name":"U.S. Public Health Service"},{"id":"https://openalex.org/G8880120036","display_name":"COLD STORAGE OF KIDNEYS FOR TRANSPLANTATION","funder_award_id":"R01DK056835","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1568437985","https://openalex.org/W1600690434","https://openalex.org/W1829187584","https://openalex.org/W1967593017","https://openalex.org/W1991851525","https://openalex.org/W2005894414","https://openalex.org/W2009183800","https://openalex.org/W2013698212","https://openalex.org/W2016203818","https://openalex.org/W2019003542","https://openalex.org/W2020859230","https://openalex.org/W2039403847","https://openalex.org/W2041553103","https://openalex.org/W2046658387","https://openalex.org/W2050971607","https://openalex.org/W2056183344","https://openalex.org/W2057295464","https://openalex.org/W2058112032","https://openalex.org/W2061754921","https://openalex.org/W2072256632","https://openalex.org/W2088786552","https://openalex.org/W2096208007","https://openalex.org/W2115485369","https://openalex.org/W2163983229","https://openalex.org/W2412300124","https://openalex.org/W2425978794"],"related_works":["https://openalex.org/W1977120555","https://openalex.org/W2397789822","https://openalex.org/W2072353087","https://openalex.org/W3096562245","https://openalex.org/W2031783595","https://openalex.org/W2128451405","https://openalex.org/W2075026527","https://openalex.org/W2031826756","https://openalex.org/W2030802562","https://openalex.org/W2061762822"],"abstract_inverted_index":{"Heme":[0],"oxygenase-1":[1],"(HO-1),":[2],"a":[3,14,38,42,68,78,130,168],"32-kd":[4],"microsomal":[5],"enzyme,":[6],"is":[7],"induced":[8],"as":[9,101],"an":[10,85,102],"adaptive":[11],"response":[12],"to":[13,119],"wide":[15],"variety":[16],"of":[17,25,30,53,114,143,159],"injurious":[18],"stimuli.":[19],"We":[20],"examined":[21],"the":[22,94,111],"possible":[23],"role":[24],"HO-1":[26,46,63,120,131,137,144,160],"in":[27,45,73,81,96,140,174],"cold":[28,58,135,151,162,176],"storage":[29,59],"renal":[31],"proximal":[32],"tubular":[33],"epithelial":[34],"(RPTE)":[35],"cells.":[36],"Hemin,":[37],"potent":[39],"HO-1-inducer,":[40],"caused":[41],"time-dependent":[43],"increase":[44,72,80,95],"mRNA":[47],"and":[48,70,77,93,146],"protein":[49,64,145],"expression.":[50],"Hemin":[51],"pretreatment":[52],"human":[54],"RPTE":[55],"cells":[56,128],"before":[57,134],"conferred":[60],"cytoprotection.":[61],"Increased":[62],"was":[65,117],"associated":[66],"with":[67,129],"brisk":[69],"early":[71],"catalytically":[74],"active":[75],"iron":[76,86,91,99],"robust":[79],"cellular":[82],"ferritin.":[83],"Deferoxamine,":[84],"sequestrating":[87],"antioxidant,":[88],"prevented":[89],"hemin-induced":[90],"release":[92,100],"ferritin,":[97],"suggesting":[98],"antecedent":[103],"mechanism":[104],"for":[105],"ferritin":[106],"induction.":[107],"To":[108],"verify":[109],"that":[110,156,167],"proximate":[112],"cause":[113],"hemin":[115],"cytoprotection":[116],"due":[118],"induction,":[121],"we":[122],"transiently":[123],"transfected":[124],"LL-CPK1":[125],"porcine":[126],"kidney":[127],"expression":[132,142],"vector":[133],"storage.":[136,152],"transfection":[138],"resulted":[139],"increased":[141],"reduced":[147],"cell":[148,164],"injury":[149,165],"during":[150,180],"The":[153],"novel":[154],"observation":[155],"prior":[157],"induction":[158],"prevents":[161],"storage-induced":[163,177],"suggests":[166],"similar":[169],"strategy":[170],"may":[171],"prove":[172],"efficacious":[173],"preventing":[175],"organ":[178],"damage":[179],"transplantation.":[181]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}