{"id":"https://openalex.org/W2013159479","doi":"https://doi.org/10.1016/0278-6915(89)90141-5","title":"Dysregulation of IgA production and IgA nephropathy induced by the trichothecene vomitoxin","display_name":"Dysregulation of IgA production and IgA nephropathy induced by the trichothecene vomitoxin","publication_year":1989,"publication_date":"1989-01-01","ids":{"openalex":"https://openalex.org/W2013159479","doi":"https://doi.org/10.1016/0278-6915(89)90141-5","mag":"2013159479","pmid":"https://pubmed.ncbi.nlm.nih.gov/2676788"},"language":"en","primary_location":{"id":"doi:10.1016/0278-6915(89)90141-5","doi":"https://doi.org/10.1016/0278-6915(89)90141-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0278-6915(89)90141-5","pdf_url":null,"source":{"id":"https://openalex.org/S84231135","display_name":"Food and Chemical Toxicology","issn_l":"0278-6915","issn":["0278-6915","1873-6351"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food and Chemical Toxicology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060677752","display_name":"James J. Pestka","orcid":"https://orcid.org/0000-0003-4689-2756","observed_orcids":["https://orcid.org/0000-0003-4689-2756"]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"J.J. Pestka","raw_affiliation_strings":["Department of Food Science and Human Nutrition, Michigan State University, East Lansing 48824","#N#        Department of Food Science and Human Nutrition, Michigan State University, East Lansing 48824"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Food Science and Human Nutrition, Michigan State University, East Lansing 48824","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"#N#        Department of Food Science and Human Nutrition, Michigan State University, East Lansing 48824","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112196905","display_name":"Mark A. Moorman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M.A. Moorman","raw_affiliation_strings":["Center for Environmental Toxicology, Michigan State University, East Lansing, MI 48824, USA","Department of Food Science and Human Nutrition Michigan State University, East Lansing, MI 48824, USA","Department of Microbiology and Public Health, Michigan State University, East Lansing, MI 48824, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Environmental Toxicology, Michigan State University, East Lansing, MI 48824, USA","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Department of Food Science and Human Nutrition Michigan State University, East Lansing, MI 48824, USA","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Department of Microbiology and Public Health, Michigan State University, East Lansing, MI 48824, USA","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111510941","display_name":"R.L. Warner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R.L. Warner","raw_affiliation_strings":["Center for Environmental Toxicology, Michigan State University, East Lansing, MI 48824, USA","Department of Food Science and Human Nutrition Michigan State University, East Lansing, MI 48824, USA","Department of Microbiology and Public Health, Michigan State University, East Lansing, MI 48824, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Environmental Toxicology, Michigan State University, East Lansing, MI 48824, USA","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Department of Food Science and Human Nutrition Michigan State University, East Lansing, MI 48824, USA","institution_ids":["https://openalex.org/I87216513"]},{"raw_affiliation_string":"Department of Microbiology and Public Health, Michigan State University, East Lansing, MI 48824, USA","institution_ids":["https://openalex.org/I87216513"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5060677752"],"corresponding_institution_ids":["https://openalex.org/I87216513"],"apc_list":{"value":4670,"currency":"USD","value_usd":4670},"apc_paid":null,"fwci":6.0339,"has_fulltext":false,"cited_by_count":110,"citation_normalized_percentile":{"value":0.96131026,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"27","issue":"6","first_page":"361","last_page":"368"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10520","display_name":"Mycotoxins in Agriculture and Food","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10520","display_name":"Mycotoxins in Agriculture and Food","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.007400000002235174,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/deoxynivalenol","display_name":"deoxynivalenol","score":0.8510000109672546},{"id":"https://openalex.org/keywords/trichothecenes","display_name":"trichothecenes","score":0.8999999761581421},{"id":"https://openalex.org/keywords/iga-nephropathy","display_name":"IgA nephropathy","score":0.9580000042915344},{"id":"https://openalex.org/keywords/immunoglobulin-a","display_name":"immunoglobulin A","score":0.796999990940094},{"id":"https://openalex.org/keywords/serum-iga","display_name":"serum IgA","score":0.6129999756813049},{"id":"https://openalex.org/keywords/dietary-mycotoxin-exposure","display_name":"dietary mycotoxin exposure","score":0.847000002861023},{"id":"https://openalex.org/keywords/monomeric-iga","display_name":"monomeric IgA","score":0.6729999780654907},{"id":"https://openalex.org/keywords/polymeric-iga","display_name":"polymeric IgA","score":0.9810000061988831},{"id":"https://openalex.org/keywords/igg","display_name":"IgG","score":0.5640000104904175},{"id":"https://openalex.org/keywords/igm","display_name":"IgM","score":0.9940000176429749},{"id":"https://openalex.org/keywords/glomerulonephritis","display_name":"glomerulonephritis","score":0.9409999847412109},{"id":"https://openalex.org/keywords/splenocyte-proliferation","display_name":"splenocyte proliferation","score":0.6909999847412109},{"id":"https://openalex.org/keywords/b6c3f1-mice","display_name":"B6C3F1 mice","score":0.8349999785423279}],"concepts":[{"id":"https://openalex.org/C2779741023","wikidata":"https://www.wikidata.org/wiki/Q420518","display_name":"Vomitoxin","level":4,"score":0.6045603156089783},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5841546654701233},{"id":"https://openalex.org/C2781184683","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Nephropathy","level":3,"score":0.5800340175628662},{"id":"https://openalex.org/C2779102806","wikidata":"https://www.wikidata.org/wiki/Q79453","display_name":"Immunoglobulin A","level":4,"score":0.5415648818016052},{"id":"https://openalex.org/C2776889654","wikidata":"https://www.wikidata.org/wiki/Q257954","display_name":"Trichothecene","level":3,"score":0.5054335594177246},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5040627717971802},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4857921600341797},{"id":"https://openalex.org/C2777991845","wikidata":"https://www.wikidata.org/wiki/Q2396793","display_name":"Isotype","level":4,"score":0.4488242268562317},{"id":"https://openalex.org/C2780368995","wikidata":"https://www.wikidata.org/wiki/Q605006","display_name":"Glomerulonephritis","level":3,"score":0.4199877977371216},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.38662683963775635},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.36835578083992004},{"id":"https://openalex.org/C2780898057","wikidata":"https://www.wikidata.org/wiki/Q79448","display_name":"Immunoglobulin G","level":3,"score":0.3653952181339264},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.2019326388835907},{"id":"https://openalex.org/C2777367657","wikidata":"https://www.wikidata.org/wiki/Q184651","display_name":"Toxin","level":2,"score":0.1801758110523224},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1517917513847351},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.1127181351184845},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.11089497804641724},{"id":"https://openalex.org/C84699730","wikidata":"https://www.wikidata.org/wiki/Q422449","display_name":"Mycotoxin","level":2,"score":0.10925304889678955},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.0},{"id":"https://openalex.org/C2777140777","wikidata":"https://www.wikidata.org/wiki/Q169326","display_name":"Zearalenone","level":3,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004032","descriptor_name":"Diet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005455","descriptor_name":"Fluorescent Antibody Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005922","descriptor_name":"Glomerulonephritis, IGA","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D005922","descriptor_name":"Glomerulonephritis, IGA","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D007070","descriptor_name":"Immunoglobulin A","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008809","descriptor_name":"Mice, Inbred C3H","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012717","descriptor_name":"Sesquiterpenes","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D014255","descriptor_name":"Trichothecenes","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D014255","descriptor_name":"Trichothecenes","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0278-6915(89)90141-5","doi":"https://doi.org/10.1016/0278-6915(89)90141-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0278-6915(89)90141-5","pdf_url":null,"source":{"id":"https://openalex.org/S84231135","display_name":"Food and Chemical Toxicology","issn_l":"0278-6915","issn":["0278-6915","1873-6351"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food and Chemical Toxicology","raw_type":"journal-article"},{"id":"pmid:2676788","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2676788","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1217047587","display_name":null,"funder_award_id":"ES03358","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"}],"funders":[{"id":"https://openalex.org/F4320337361","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W62771806","https://openalex.org/W293462589","https://openalex.org/W1508067238","https://openalex.org/W1524652166","https://openalex.org/W1552392913","https://openalex.org/W1570765894","https://openalex.org/W1947114133","https://openalex.org/W1965507909","https://openalex.org/W1975985686","https://openalex.org/W1985851585","https://openalex.org/W1986416293","https://openalex.org/W1995247657","https://openalex.org/W2014467313","https://openalex.org/W2016188743","https://openalex.org/W2025254645","https://openalex.org/W2026024653","https://openalex.org/W2036550192","https://openalex.org/W2037322571","https://openalex.org/W2039549505","https://openalex.org/W2070148516","https://openalex.org/W2075473536","https://openalex.org/W2085405913","https://openalex.org/W2090828619","https://openalex.org/W2096887849","https://openalex.org/W2101108802","https://openalex.org/W2111301002","https://openalex.org/W2111828987","https://openalex.org/W2118067399","https://openalex.org/W2137981684","https://openalex.org/W2159012191","https://openalex.org/W2313659229","https://openalex.org/W2318589655","https://openalex.org/W2414508260","https://openalex.org/W4235858129"],"related_works":["https://openalex.org/W4238348407","https://openalex.org/W7099905870","https://openalex.org/W2164856533","https://openalex.org/W4242837602","https://openalex.org/W1994612708","https://openalex.org/W2053582362","https://openalex.org/W1965765751","https://openalex.org/W2069254997","https://openalex.org/W2089394117","https://openalex.org/W2022546686"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":5},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}