{"id":"https://openalex.org/W2013152933","doi":"https://doi.org/10.1016/j.neuroscience.2011.08.061","title":"Molecular genetics of mouse serotonin neurons across the lifespan","display_name":"Molecular genetics of mouse serotonin neurons across the lifespan","publication_year":2011,"publication_date":"2011-09-01","ids":{"openalex":"https://openalex.org/W2013152933","doi":"https://doi.org/10.1016/j.neuroscience.2011.08.061","mag":"2013152933","pmid":"https://pubmed.ncbi.nlm.nih.gov/21920412","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3295611"},"language":"en","primary_location":{"id":"doi:10.1016/j.neuroscience.2011.08.061","doi":"https://doi.org/10.1016/j.neuroscience.2011.08.061","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neuroscience.2011.08.061","pdf_url":null,"source":{"id":"https://openalex.org/S30122339","display_name":"Neuroscience","issn_l":"0306-4522","issn":["0306-4522","1873-7544"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3295611/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023395524","display_name":"Evan S. Deneris","orcid":"https://orcid.org/0000-0003-4211-9934","observed_orcids":["https://orcid.org/0000-0003-4211-9934"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"E.S. Deneris","raw_affiliation_strings":["Case Western Reserve University, School of Medicine, Department of Neurosciences, Cleveland, OH 44106, USA. esd@case.edu","Case Western Reserve University, School of Medicine, Department of Neurosciences, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Case Western Reserve University, School of Medicine, Department of Neurosciences, Cleveland, OH 44106, USA. esd@case.edu","institution_ids":["https://openalex.org/I58956616"]},{"raw_affiliation_string":"Case Western Reserve University, School of Medicine, Department of Neurosciences, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5023395524"],"corresponding_institution_ids":["https://openalex.org/I58956616"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":null,"fwci":0.3017,"has_fulltext":false,"cited_by_count":34,"citation_normalized_percentile":{"value":0.2,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"197","issue":null,"first_page":"17","last_page":"27"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.7958999872207642,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.7958999872207642,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.10740000009536743,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.03400000184774399,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/serotonergic-neurons","display_name":"serotonergic neurons","score":0.9860000014305115},{"id":"https://openalex.org/keywords/ets-transcription-factors","display_name":"ETS transcription factors","score":0.9279999732971191},{"id":"https://openalex.org/keywords/transgenic-mouse-lines","display_name":"transgenic mouse lines","score":0.5600000023841858},{"id":"https://openalex.org/keywords/conditional-gene-expression","display_name":"conditional gene expression","score":0.6050000190734863},{"id":"https://openalex.org/keywords/neuronal-identity","display_name":"neuronal identity","score":0.4970000088214874},{"id":"https://openalex.org/keywords/maternal-behavior","display_name":"maternal behavior","score":0.597000002861023},{"id":"https://openalex.org/keywords/emotional-behavior","display_name":"emotional behavior","score":0.6930000185966492},{"id":"https://openalex.org/keywords/thermoregulation","display_name":"thermoregulation","score":0.8949999809265137},{"id":"https://openalex.org/keywords/respiration","display_name":"respiration","score":0.968999981880188}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7885081768035889},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6864960789680481},{"id":"https://openalex.org/C2778794669","wikidata":"https://www.wikidata.org/wiki/Q43054","display_name":"Neuron","level":2,"score":0.612700343132019},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.48321664333343506},{"id":"https://openalex.org/C102230213","wikidata":"https://www.wikidata.org/wiki/Q430117","display_name":"Transgene","level":3,"score":0.43134626746177673},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.30445432662963867},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1920783519744873}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008822","descriptor_name":"Mice, Transgenic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008967","descriptor_name":"Molecular Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055495","descriptor_name":"Neurogenesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.neuroscience.2011.08.061","doi":"https://doi.org/10.1016/j.neuroscience.2011.08.061","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neuroscience.2011.08.061","pdf_url":null,"source":{"id":"https://openalex.org/S30122339","display_name":"Neuroscience","issn_l":"0306-4522","issn":["0306-4522","1873-7544"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience","raw_type":"journal-article"},{"id":"pmid:21920412","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21920412","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3295611","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3295611/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Neuroscience","raw_type":"Text"},{"id":"mag:2184944947","doi":null,"is_oa":false,"landing_page_url":"http://knockout.cwru.edu/publications/deneris.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3295611","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3295611/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Neuroscience","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3204767367","display_name":"Genes Controlling Assembly and Function of Serotonin Systems","funder_award_id":"P50MH078028","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G6566227676","display_name":"genetic mechanisms controlling serotonergic function across life span","funder_award_id":"R01MH062723","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":74,"referenced_works":["https://openalex.org/W1965070710","https://openalex.org/W1968415875","https://openalex.org/W1974052352","https://openalex.org/W1976114760","https://openalex.org/W1976494054","https://openalex.org/W1985057945","https://openalex.org/W1985713454","https://openalex.org/W1987299915","https://openalex.org/W1994671021","https://openalex.org/W1994918767","https://openalex.org/W1995120027","https://openalex.org/W1996033370","https://openalex.org/W1996694057","https://openalex.org/W1997749666","https://openalex.org/W1998712336","https://openalex.org/W1999669401","https://openalex.org/W2000827148","https://openalex.org/W2004886688","https://openalex.org/W2005713680","https://openalex.org/W2007077740","https://openalex.org/W2012120903","https://openalex.org/W2013946968","https://openalex.org/W2014711343","https://openalex.org/W2019143604","https://openalex.org/W2020460680","https://openalex.org/W2024628648","https://openalex.org/W2030081504","https://openalex.org/W2031890731","https://openalex.org/W2035221267","https://openalex.org/W2036691617","https://openalex.org/W2038174426","https://openalex.org/W2038771513","https://openalex.org/W2039338324","https://openalex.org/W2041052894","https://openalex.org/W2041174212","https://openalex.org/W2048213004","https://openalex.org/W2052784390","https://openalex.org/W2055135519","https://openalex.org/W2055466946","https://openalex.org/W2055760464","https://openalex.org/W2065502256","https://openalex.org/W2074425528","https://openalex.org/W2075464370","https://openalex.org/W2077552160","https://openalex.org/W2079061045","https://openalex.org/W2080040046","https://openalex.org/W2081784716","https://openalex.org/W2085542890","https://openalex.org/W2087547939","https://openalex.org/W2088131432","https://openalex.org/W2088249036","https://openalex.org/W2094765055","https://openalex.org/W2095148356","https://openalex.org/W2098698941","https://openalex.org/W2099426422","https://openalex.org/W2106218592","https://openalex.org/W2107736130","https://openalex.org/W2110654827","https://openalex.org/W2114773717","https://openalex.org/W2115182798","https://openalex.org/W2126307255","https://openalex.org/W2126816262","https://openalex.org/W2133847377","https://openalex.org/W2135190897","https://openalex.org/W2142401824","https://openalex.org/W2142771373","https://openalex.org/W2152069082","https://openalex.org/W2158271326","https://openalex.org/W2158770881","https://openalex.org/W2163769225","https://openalex.org/W2167244529","https://openalex.org/W2171055927","https://openalex.org/W2171786302","https://openalex.org/W2317783677"],"related_works":["https://openalex.org/W2184944947","https://openalex.org/W2007077740","https://openalex.org/W2052784390","https://openalex.org/W2114773717","https://openalex.org/W2736720916","https://openalex.org/W2313592313","https://openalex.org/W2041741280","https://openalex.org/W2171786302","https://openalex.org/W7002211682","https://openalex.org/W2152069082"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}