{"id":"https://openalex.org/W2013017465","doi":"https://doi.org/10.1378/chest.114.1_supplement.101s","title":"The Pressure-Overloaded Right Ventricle in Pulmonary Hypertension","display_name":"The Pressure-Overloaded Right Ventricle in Pulmonary Hypertension","publication_year":1998,"publication_date":"1998-07-01","ids":{"openalex":"https://openalex.org/W2013017465","doi":"https://doi.org/10.1378/chest.114.1_supplement.101s","mag":"2013017465","pmid":"https://pubmed.ncbi.nlm.nih.gov/9676654"},"language":"en","primary_location":{"id":"doi:10.1378/chest.114.1_supplement.101s","doi":"https://doi.org/10.1378/chest.114.1_supplement.101s","is_oa":false,"landing_page_url":"https://doi.org/10.1378/chest.114.1_supplement.101s","pdf_url":null,"source":{"id":"https://openalex.org/S76900504","display_name":"CHEST Journal","issn_l":"0012-3692","issn":["0012-3692","1931-3543"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chest","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042834490","display_name":"Michael R. Bristow","orcid":"https://orcid.org/0000-0002-8860-4698","observed_orcids":["https://orcid.org/0000-0002-8860-4698"]},"institutions":[{"id":"https://openalex.org/I4210087413","display_name":"University of Colorado Health","ror":"https://ror.org/0107w4315","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087413"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael R. Bristow","raw_affiliation_strings":["Division of Cardiology, University of Colorado Health Science Center, Denver, USA","From the Division of Cardiology, University of Colorado Health Science Center, Denver"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, University of Colorado Health Science Center, Denver, USA","institution_ids":["https://openalex.org/I4210087413","https://openalex.org/I921990950"]},{"raw_affiliation_string":"From the Division of Cardiology, University of Colorado Health Science Center, Denver","institution_ids":["https://openalex.org/I4210087413","https://openalex.org/I921990950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043266213","display_name":"Lawrence S. Zisman","orcid":"https://orcid.org/0000-0002-7975-4707","observed_orcids":["https://orcid.org/0000-0002-7975-4707"]},"institutions":[{"id":"https://openalex.org/I4210087413","display_name":"University of Colorado Health","ror":"https://ror.org/0107w4315","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087413"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lawrence S. Zisman","raw_affiliation_strings":["From the Division of Cardiology, University of Colorado Health Science Center, Denver"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Cardiology, University of Colorado Health Science Center, Denver","institution_ids":["https://openalex.org/I4210087413","https://openalex.org/I921990950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088568680","display_name":"Brian D. Lowes","orcid":"https://orcid.org/0000-0002-5919-2540","observed_orcids":["https://orcid.org/0000-0002-5919-2540"]},"institutions":[{"id":"https://openalex.org/I4210087413","display_name":"University of Colorado Health","ror":"https://ror.org/0107w4315","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087413"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian D. Lowes","raw_affiliation_strings":["From the Division of Cardiology, University of Colorado Health Science Center, Denver"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Cardiology, University of Colorado Health Science Center, Denver","institution_ids":["https://openalex.org/I4210087413","https://openalex.org/I921990950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066384461","display_name":"William T. Abraham","orcid":"https://orcid.org/0000-0003-4805-1037","observed_orcids":["https://orcid.org/0000-0003-4805-1037"]},"institutions":[{"id":"https://openalex.org/I4210087413","display_name":"University of Colorado Health","ror":"https://ror.org/0107w4315","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087413"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William T. Abraham","raw_affiliation_strings":["From the Division of Cardiology, University of Colorado Health Science Center, Denver"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Cardiology, University of Colorado Health Science Center, Denver","institution_ids":["https://openalex.org/I4210087413","https://openalex.org/I921990950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056518661","display_name":"David B. Badesch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087413","display_name":"University of Colorado Health","ror":"https://ror.org/0107w4315","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087413"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David B. Badesch","raw_affiliation_strings":["From the Division of Cardiology, University of Colorado Health Science Center, Denver"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Cardiology, University of Colorado Health Science Center, Denver","institution_ids":["https://openalex.org/I4210087413","https://openalex.org/I921990950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111519260","display_name":"Bertron \u039c. Groves","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087413","display_name":"University of Colorado Health","ror":"https://ror.org/0107w4315","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087413"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bertron M. Groves","raw_affiliation_strings":["From the Division of Cardiology, University of Colorado Health Science Center, Denver"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Cardiology, University of Colorado Health Science Center, Denver","institution_ids":["https://openalex.org/I4210087413","https://openalex.org/I921990950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111677624","display_name":"Norbert Felix Voelkel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087413","display_name":"University of Colorado Health","ror":"https://ror.org/0107w4315","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087413"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Norbert F. Voelkel","raw_affiliation_strings":["From the Division of Cardiology, University of Colorado Health Science Center, Denver"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Cardiology, University of Colorado Health Science Center, Denver","institution_ids":["https://openalex.org/I4210087413","https://openalex.org/I921990950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102099062","display_name":"David M.B. Lynch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087413","display_name":"University of Colorado Health","ror":"https://ror.org/0107w4315","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087413"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David M.B. Lynch","raw_affiliation_strings":["From the Division of Cardiology, University of Colorado Health Science Center, Denver"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Cardiology, University of Colorado Health Science Center, Denver","institution_ids":["https://openalex.org/I4210087413","https://openalex.org/I921990950"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082971182","display_name":"Robert A. Quaife","orcid":"https://orcid.org/0000-0002-0695-8872","observed_orcids":["https://orcid.org/0000-0002-0695-8872"]},"institutions":[{"id":"https://openalex.org/I4210087413","display_name":"University of Colorado Health","ror":"https://ror.org/0107w4315","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087413"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert A. Quaife","raw_affiliation_strings":["From the Division of Cardiology, University of Colorado Health Science Center, Denver"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Cardiology, University of Colorado Health Science Center, Denver","institution_ids":["https://openalex.org/I4210087413","https://openalex.org/I921990950"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4160,"currency":"USD","value_usd":4160},"apc_paid":null,"fwci":2.0098,"has_fulltext":false,"cited_by_count":146,"citation_normalized_percentile":{"value":0.85709639,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"114","issue":"1","first_page":"101S","last_page":"106S"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12199","display_name":"Vascular Anomalies and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/idiopathic-pulmonary-arterial-hypertension","display_name":"idiopathic pulmonary arterial hypertension","score":0.9890000224113464},{"id":"https://openalex.org/keywords/right-ventricular-dysfunction","display_name":"right ventricular dysfunction","score":0.8989999890327454},{"id":"https://openalex.org/keywords/right-heart-failure","display_name":"right heart failure","score":0.7789999842643738},{"id":"https://openalex.org/keywords/pressure-overload","display_name":"pressure overload","score":0.7289999723434448},{"id":"https://openalex.org/keywords/pulmonary-vascular-resistance","display_name":"pulmonary vascular resistance","score":0.8460000157356262},{"id":"https://openalex.org/keywords/tricuspid-regurgitation","display_name":"tricuspid regurgitation","score":0.8149999976158142},{"id":"https://openalex.org/keywords/pulmonary-vasodilator-therapy","display_name":"pulmonary vasodilator therapy","score":0.7860000133514404},{"id":"https://openalex.org/keywords/prostacyclin","display_name":"prostacyclin","score":0.890999972820282},{"id":"https://openalex.org/keywords/calcium-channel-blockers","display_name":"calcium channel blockers","score":0.7039999961853027},{"id":"https://openalex.org/keywords/diuretics","display_name":"diuretics","score":0.824999988079071},{"id":"https://openalex.org/keywords/digoxin","display_name":"digoxin","score":0.9750000238418579},{"id":"https://openalex.org/keywords/warfarin","display_name":"warfarin","score":0.8159999847412109},{"id":"https://openalex.org/keywords/thrombosis","display_name":"thrombosis","score":0.8230000138282776},{"id":"https://openalex.org/keywords/vascular-remodeling","display_name":"vascular remodeling","score":0.5730000138282776},{"id":"https://openalex.org/keywords/cardiac-remodeling","display_name":"cardiac remodeling","score":0.671999990940094},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.5450000166893005},{"id":"https://openalex.org/keywords/natural-history-disease","display_name":"natural history (disease)","score":0.6669999957084656},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.8209999799728394},{"id":"https://openalex.org/keywords/right-ventricular-filling-pressure","display_name":"right ventricular filling pressure","score":0.6200000047683716}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8707032203674316},{"id":"https://openalex.org/C2780930700","wikidata":"https://www.wikidata.org/wiki/Q1128595","display_name":"Pulmonary hypertension","level":2,"score":0.7393110394477844},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.626610517501831},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6127272844314575},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.5172377228736877},{"id":"https://openalex.org/C155710745","wikidata":"https://www.wikidata.org/wiki/Q575278","display_name":"Inotrope","level":2,"score":0.4765784740447998},{"id":"https://openalex.org/C58245268","wikidata":"https://www.wikidata.org/wiki/Q456026","display_name":"Vascular resistance","level":3,"score":0.46983951330184937},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.43737077713012695},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.35099470615386963}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006976","descriptor_name":"Hypertension, Pulmonary","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006976","descriptor_name":"Hypertension, Pulmonary","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D007703","descriptor_name":"Peptidyl-Dipeptidase A","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018497","descriptor_name":"Ventricular Dysfunction, Right","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D018497","descriptor_name":"Ventricular Dysfunction, Right","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018497","descriptor_name":"Ventricular Dysfunction, Right","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1378/chest.114.1_supplement.101s","doi":"https://doi.org/10.1378/chest.114.1_supplement.101s","is_oa":false,"landing_page_url":"https://doi.org/10.1378/chest.114.1_supplement.101s","pdf_url":null,"source":{"id":"https://openalex.org/S76900504","display_name":"CHEST Journal","issn_l":"0012-3692","issn":["0012-3692","1931-3543"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chest","raw_type":"journal-article"},{"id":"pmid:9676654","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9676654","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chest","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W195435902","https://openalex.org/W1582334575","https://openalex.org/W1986866063","https://openalex.org/W1989282030","https://openalex.org/W1989475487","https://openalex.org/W1997208142","https://openalex.org/W2006229710","https://openalex.org/W2010346710","https://openalex.org/W2014942570","https://openalex.org/W2015415450","https://openalex.org/W2021315555","https://openalex.org/W2053890291","https://openalex.org/W2068359901","https://openalex.org/W2075228543","https://openalex.org/W2077425788","https://openalex.org/W2078395346","https://openalex.org/W2087495902","https://openalex.org/W2104475665","https://openalex.org/W2115051175","https://openalex.org/W2128867957","https://openalex.org/W2141987653","https://openalex.org/W2150907123","https://openalex.org/W2162394869","https://openalex.org/W2170542286","https://openalex.org/W2321522617","https://openalex.org/W2403669236"],"related_works":["https://openalex.org/W123423038","https://openalex.org/W2595669029","https://openalex.org/W2338767849","https://openalex.org/W2021035905","https://openalex.org/W7097889192","https://openalex.org/W4200101948","https://openalex.org/W3216308099","https://openalex.org/W1583335386","https://openalex.org/W2441742839","https://openalex.org/W1994089102"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":16},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":6}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}