{"id":"https://openalex.org/W2012959955","doi":"https://doi.org/10.1021/ac400514u","title":"A Label-Free Potentiometric Sensor Principle for the Detection of Antibody\u2013Antigen Interactions","display_name":"A Label-Free Potentiometric Sensor Principle for the Detection of Antibody\u2013Antigen Interactions","publication_year":2013,"publication_date":"2013-03-27","ids":{"openalex":"https://openalex.org/W2012959955","doi":"https://doi.org/10.1021/ac400514u","mag":"2012959955","pmid":"https://pubmed.ncbi.nlm.nih.gov/23534536"},"language":"en","primary_location":{"id":"doi:10.1021/ac400514u","doi":"https://doi.org/10.1021/ac400514u","is_oa":true,"landing_page_url":"https://doi.org/10.1021/ac400514u","pdf_url":null,"source":{"id":"https://openalex.org/S191963794","display_name":"Analytical Chemistry","issn_l":"0003-2700","issn":["0003-2700","1520-6882"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1021/ac400514u","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010338889","display_name":"Mahir Ozdemir","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137982388","display_name":"Janssen (Belgium)","ror":"https://ror.org/04yzcpd71","country_code":"BE","type":"company","lineage":["https://openalex.org/I1330063522","https://openalex.org/I137982388"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Mahir S. Ozdemir","raw_affiliation_strings":["Janssen Research & Development Pharmaceutical Development & Manufacturing Sciences, , 2340 Beerse, Belgium","Pharmaceutical Development & Manufacturing Sciences, Janssen Research & Development, 2340 Beerse, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Janssen Research & Development Pharmaceutical Development & Manufacturing Sciences, , 2340 Beerse, Belgium","institution_ids":["https://openalex.org/I137982388"]},{"raw_affiliation_string":"Pharmaceutical Development & Manufacturing Sciences, Janssen Research & Development, 2340 Beerse, Belgium","institution_ids":["https://openalex.org/I137982388"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040938243","display_name":"Marcin Marczak","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137982388","display_name":"Janssen (Belgium)","ror":"https://ror.org/04yzcpd71","country_code":"BE","type":"company","lineage":["https://openalex.org/I1330063522","https://openalex.org/I137982388"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Marcin Marczak","raw_affiliation_strings":["Janssen Research & Development Pharmaceutical Development & Manufacturing Sciences, , 2340 Beerse, Belgium","Pharmaceutical Development & Manufacturing Sciences, Janssen Research & Development, 2340 Beerse, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Janssen Research & Development Pharmaceutical Development & Manufacturing Sciences, , 2340 Beerse, Belgium","institution_ids":["https://openalex.org/I137982388"]},{"raw_affiliation_string":"Pharmaceutical Development & Manufacturing Sciences, Janssen Research & Development, 2340 Beerse, Belgium","institution_ids":["https://openalex.org/I137982388"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026224315","display_name":"Hugo Bohets","orcid":"https://orcid.org/0009-0008-2293-8020","observed_orcids":["https://orcid.org/0009-0008-2293-8020"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hugo Bohets","raw_affiliation_strings":["Octens BVBA , Sint-Michielskaai 34, 2000 Antwerpen Belgium","Octens BVBA, Sint-Michielskaai 34, 2000#R#Antwerpen Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Octens BVBA , Sint-Michielskaai 34, 2000 Antwerpen Belgium","institution_ids":[]},{"raw_affiliation_string":"Octens BVBA, Sint-Michielskaai 34, 2000#R#Antwerpen Belgium","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034947768","display_name":"Kristien Bonroy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137982388","display_name":"Janssen (Belgium)","ror":"https://ror.org/04yzcpd71","country_code":"BE","type":"company","lineage":["https://openalex.org/I1330063522","https://openalex.org/I137982388"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Kristien Bonroy","raw_affiliation_strings":["Janssen Infectious Diseases \u2212Diagnostics BVBA, 2340 Beerse, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Janssen Infectious Diseases \u2212Diagnostics BVBA, 2340 Beerse, Belgium","institution_ids":["https://openalex.org/I137982388"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034377203","display_name":"Dirk Roymans","orcid":"https://orcid.org/0000-0003-1309-415X","observed_orcids":["https://orcid.org/0000-0003-1309-415X"]},"institutions":[{"id":"https://openalex.org/I137982388","display_name":"Janssen (Belgium)","ror":"https://ror.org/04yzcpd71","country_code":"BE","type":"company","lineage":["https://openalex.org/I1330063522","https://openalex.org/I137982388"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Dirk Roymans","raw_affiliation_strings":["Janssen Infectious Diseases \u2212Diagnostics BVBA, 2340 Beerse, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Janssen Infectious Diseases \u2212Diagnostics BVBA, 2340 Beerse, Belgium","institution_ids":["https://openalex.org/I137982388"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070724386","display_name":"Lieven J. Stuyver","orcid":"https://orcid.org/0000-0001-7818-9390","observed_orcids":["https://orcid.org/0000-0001-7818-9390"]},"institutions":[{"id":"https://openalex.org/I137982388","display_name":"Janssen (Belgium)","ror":"https://ror.org/04yzcpd71","country_code":"BE","type":"company","lineage":["https://openalex.org/I1330063522","https://openalex.org/I137982388"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Lieven Stuyver","raw_affiliation_strings":["Janssen Infectious Diseases \u2212Diagnostics BVBA, 2340 Beerse, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Janssen Infectious Diseases \u2212Diagnostics BVBA, 2340 Beerse, Belgium","institution_ids":["https://openalex.org/I137982388"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050876063","display_name":"Koen Vanhoutte","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137982388","display_name":"Janssen (Belgium)","ror":"https://ror.org/04yzcpd71","country_code":"BE","type":"company","lineage":["https://openalex.org/I1330063522","https://openalex.org/I137982388"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Koen Vanhoutte","raw_affiliation_strings":["Janssen Research & Development Pharmaceutical Development & Manufacturing Sciences, , 2340 Beerse, Belgium","Pharmaceutical Development & Manufacturing Sciences, Janssen Research & Development, 2340 Beerse, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Janssen Research & Development Pharmaceutical Development & Manufacturing Sciences, , 2340 Beerse, Belgium","institution_ids":["https://openalex.org/I137982388"]},{"raw_affiliation_string":"Pharmaceutical Development & Manufacturing Sciences, Janssen Research & Development, 2340 Beerse, Belgium","institution_ids":["https://openalex.org/I137982388"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085636559","display_name":"Marcin Pawlak","orcid":"https://orcid.org/0000-0003-4124-1698","observed_orcids":["https://orcid.org/0000-0003-4124-1698"]},"institutions":[{"id":"https://openalex.org/I114457229","display_name":"University of Geneva","ror":"https://ror.org/01swzsf04","country_code":"CH","type":"education","lineage":["https://openalex.org/I114457229"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Marcin Pawlak","raw_affiliation_strings":["University of Geneva , , Quai E.-Ansermet 30, CH-1211 Geneva, Switzerland","Department of Inorganic#R#and Analytical Chemistry, University of Geneva, Quai E.-Ansermet 30, CH-1211 Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Geneva , , Quai E.-Ansermet 30, CH-1211 Geneva, Switzerland","institution_ids":["https://openalex.org/I114457229"]},{"raw_affiliation_string":"Department of Inorganic#R#and Analytical Chemistry, University of Geneva, Quai E.-Ansermet 30, CH-1211 Geneva, Switzerland","institution_ids":["https://openalex.org/I114457229"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016418669","display_name":"Eric Bakker","orcid":"https://orcid.org/0000-0001-8970-4343","observed_orcids":["https://orcid.org/0000-0001-8970-4343"]},"institutions":[{"id":"https://openalex.org/I114457229","display_name":"University of Geneva","ror":"https://ror.org/01swzsf04","country_code":"CH","type":"education","lineage":["https://openalex.org/I114457229"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Eric Bakker","raw_affiliation_strings":["University of Geneva , , Quai E.-Ansermet 30, CH-1211 Geneva, Switzerland","Department of Inorganic#R#and Analytical Chemistry, University of Geneva, Quai E.-Ansermet 30, CH-1211 Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Geneva , , Quai E.-Ansermet 30, CH-1211 Geneva, Switzerland","institution_ids":["https://openalex.org/I114457229"]},{"raw_affiliation_string":"Department of Inorganic#R#and Analytical Chemistry, University of Geneva, Quai E.-Ansermet 30, CH-1211 Geneva, Switzerland","institution_ids":["https://openalex.org/I114457229"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5016418669"],"corresponding_institution_ids":["https://openalex.org/I114457229"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":{"value":4500,"currency":"USD","value_usd":4500},"fwci":4.6603,"has_fulltext":false,"cited_by_count":62,"citation_normalized_percentile":{"value":0.95751377,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"85","issue":"9","first_page":"4770","last_page":"4776"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.005499999970197678,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ion-selective-membranes","display_name":"ion-selective membranes","score":0.8560000061988831},{"id":"https://openalex.org/keywords/respiratory-syncytial-virus","display_name":"respiratory syncytial virus","score":0.8759999871253967},{"id":"https://openalex.org/keywords/click-chemistry","display_name":"click chemistry","score":0.828000009059906},{"id":"https://openalex.org/keywords/polyvinyl-chloride-membrane","display_name":"PVC membrane","score":0.7020000219345093},{"id":"https://openalex.org/keywords/quaternary-ammonium-ions","display_name":"quaternary ammonium ions","score":0.871999979019165},{"id":"https://openalex.org/keywords/biotin-streptavidin","display_name":"biotin-streptavidin","score":0.7570000290870667},{"id":"https://openalex.org/keywords/point-of-care-testing","display_name":"point-of-care testing","score":0.6520000100135803},{"id":"https://openalex.org/keywords/quartz-crystal-microbalance","display_name":"quartz crystal microbalance","score":0.6669999957084656}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9166197180747986},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.7489543557167053},{"id":"https://openalex.org/C204628709","wikidata":"https://www.wikidata.org/wiki/Q864854","display_name":"Biotinylation","level":2,"score":0.7096949219703674},{"id":"https://openalex.org/C124614425","wikidata":"https://www.wikidata.org/wiki/Q1813495","display_name":"Potentiometric titration","level":3,"score":0.6124382019042969},{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.5593210458755493},{"id":"https://openalex.org/C2776190903","wikidata":"https://www.wikidata.org/wiki/Q421817","display_name":"Streptavidin","level":3,"score":0.5160838961601257},{"id":"https://openalex.org/C9996572","wikidata":"https://www.wikidata.org/wiki/Q629569","display_name":"Quartz crystal microbalance","level":3,"score":0.47104430198669434},{"id":"https://openalex.org/C119128265","wikidata":"https://www.wikidata.org/wiki/Q900165","display_name":"Detection limit","level":2,"score":0.44807010889053345},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.44057056307792664},{"id":"https://openalex.org/C145148216","wikidata":"https://www.wikidata.org/wiki/Q36496","display_name":"Ion","level":2,"score":0.31570011377334595},{"id":"https://openalex.org/C2778204606","wikidata":"https://www.wikidata.org/wiki/Q181354","display_name":"Biotin","level":2,"score":0.3114788234233856},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.17886260151863098},{"id":"https://openalex.org/C150394285","wikidata":"https://www.wikidata.org/wiki/Q180254","display_name":"Adsorption","level":2,"score":0.15036407113075256},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.12548419833183289}],"mesh":[{"descriptor_ui":"D000906","descriptor_name":"Antibodies","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000937","descriptor_name":"Antigen-Antibody Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004566","descriptor_name":"Electrodes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011199","descriptor_name":"Potentiometry","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D012136","descriptor_name":"Respiratory Syncytial Viruses","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013499","descriptor_name":"Surface Properties","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1021/ac400514u","doi":"https://doi.org/10.1021/ac400514u","is_oa":true,"landing_page_url":"https://doi.org/10.1021/ac400514u","pdf_url":null,"source":{"id":"https://openalex.org/S191963794","display_name":"Analytical Chemistry","issn_l":"0003-2700","issn":["0003-2700","1520-6882"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical Chemistry","raw_type":"journal-article"},{"id":"pmid:23534536","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23534536","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical chemistry","raw_type":"Journal Article"},{"id":"pmh:oai:unige.ch:unige:31449","doi":null,"is_oa":false,"landing_page_url":"https://archive-ouverte.unige.ch/unige:31449","pdf_url":null,"source":{"id":"https://openalex.org/S4306402259","display_name":"Archive ouverte UNIGE (University of Geneva)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114457229","host_organization_name":"University of Geneva","host_organization_lineage":["https://openalex.org/I114457229"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ISSN: 0003-2700","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:unige.ch:aou:unige:31449","doi":null,"is_oa":true,"landing_page_url":"https://archive-ouverte.unige.ch/unige:31449","pdf_url":null,"source":{"id":"https://openalex.org/S4306402259","display_name":"Archive ouverte UNIGE (University of Geneva)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114457229","host_organization_name":"University of Geneva","host_organization_lineage":["https://openalex.org/I114457229"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 0003-2700","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1021/ac400514u","doi":"https://doi.org/10.1021/ac400514u","is_oa":true,"landing_page_url":"https://doi.org/10.1021/ac400514u","pdf_url":null,"source":{"id":"https://openalex.org/S191963794","display_name":"Analytical Chemistry","issn_l":"0003-2700","issn":["0003-2700","1520-6882"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1976726504","https://openalex.org/W1987959303","https://openalex.org/W1989368177","https://openalex.org/W1994982992","https://openalex.org/W2002910847","https://openalex.org/W2019706667","https://openalex.org/W2058651751","https://openalex.org/W2062528273","https://openalex.org/W2073113652","https://openalex.org/W2085112983","https://openalex.org/W2088110618","https://openalex.org/W2109831018","https://openalex.org/W2112030528","https://openalex.org/W2125843387","https://openalex.org/W2141504585","https://openalex.org/W2143908604"],"related_works":["https://openalex.org/W57176718","https://openalex.org/W2030166185","https://openalex.org/W2043857759","https://openalex.org/W2039574949","https://openalex.org/W2946811475","https://openalex.org/W2054154331","https://openalex.org/W2079025922","https://openalex.org/W1992674053","https://openalex.org/W2058622044","https://openalex.org/W2792461921"],"abstract_inverted_index":{"We":[0],"report":[1],"here":[2],"on":[3,108,156],"a":[4,25,28,40,45,78,101,195],"new":[5],"potentiometric":[6],"biosensing":[7],"principle":[8],"for":[9],"the":[10,16,21,32,49,52,59,63,72,109,116,137,149,157,174,178,182,187],"detection":[11],"of":[12,44,115,151,177,186,194],"antibody-antigen":[13],"interactions":[14],"at":[15,58,71],"sensing":[17,60,161],"membrane":[18,50,73,158],"surface":[19,61,74],"without":[20],"need":[22],"to":[23,31,145,192],"add":[24],"label":[26],"or":[27],"reporter":[29],"ion":[30,47,134],"sample":[33],"solution.":[34,54],"This":[35],"is":[36],"accomplished":[37],"by":[38,148],"establishing":[39],"steady-state":[41],"outward":[42],"flux":[43],"marker":[46,64,138,179],"from":[48,181],"into":[51],"contacting":[53],"The":[55,81,118,140,160,184],"immunobinding":[56],"event":[57],"retards":[62],"ion,":[65],"which":[66],"results":[67],"in":[68,77],"its":[69],"accumulation":[70],"and":[75,104,127,170],"hence":[76],"potential":[79,142],"response.":[80],"ion-selective":[82],"membranes":[83],"were":[84],"surface-modified":[85],"with":[86,100,125,165,200],"an":[87,105],"antibody":[88],"against":[89],"respiratory":[90,152],"syncytial":[91,153],"virus":[92,154],"using":[93],"click":[94],"chemistry":[95],"between":[96],"biotin":[97],"molecules":[98],"functionalized":[99],"triple":[102],"bond":[103],"azide":[106],"group":[107,114],"modified":[110],"poly":[111],"(vinyl":[112],"chloride)":[113],"membrane.":[117,183],"bioassay":[119],"sensor":[120,189],"was":[121,143,163,190],"then":[122],"built":[123],"up":[124],"streptavidin":[126],"subsequent":[128],"biotinylated":[129],"antibody.":[130],"A":[131],"quaternary":[132],"ammonium":[133],"served":[135],"as":[136],"ion.":[139],"observed":[141],"found":[144],"be":[146],"modulated":[147],"presence":[150],"bound":[155],"surface.":[159],"architecture":[162],"confirmed":[164,173],"quartz":[166],"crystal":[167],"microbalance":[168],"studies,":[169],"stir":[171],"effects":[172],"kinetic":[175],"nature":[176],"release":[180],"sensitivity":[185],"model":[188],"compared":[191],"that":[193],"commercially":[196],"available":[197],"point-of-care":[198],"test,":[199],"promising":[201],"results.":[202]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}