{"id":"https://openalex.org/W2012564010","doi":"https://doi.org/10.3109/17453679608997761","title":"Extracorporeal irradiation and incorporation of bone grafts: Autogeneic cortical grafts studied in rats","display_name":"Extracorporeal irradiation and incorporation of bone grafts: Autogeneic cortical grafts studied in rats","publication_year":1996,"publication_date":"1996-01-01","ids":{"openalex":"https://openalex.org/W2012564010","doi":"https://doi.org/10.3109/17453679608997761","mag":"2012564010","pmid":"https://pubmed.ncbi.nlm.nih.gov/9065072"},"language":"en","primary_location":{"id":"doi:10.3109/17453679608997761","doi":"https://doi.org/10.3109/17453679608997761","is_oa":false,"landing_page_url":"https://doi.org/10.3109/17453679608997761","pdf_url":null,"source":{"id":"https://openalex.org/S198708498","display_name":"Acta Orthopaedica Scandinavica","issn_l":"0001-6470","issn":["0001-6470"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Orthopaedica Scandinavica","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://actaorthop.org/actao/article/download/21053/24888","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059630940","display_name":"G. Voggenreiter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119759","display_name":"Essen University Hospital","ror":"https://ror.org/02na8dn90","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210119759"]},{"id":"https://openalex.org/I4405270573","display_name":"Stiftung Universit\u00e4tsmedizin Essen","ror":"https://ror.org/00ykp8811","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I4405270573"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Gregor Voggenreiter","raw_affiliation_strings":["Department of Trauma Surgery, University Clinic, Essen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Trauma Surgery, University Clinic, Essen, Germany","institution_ids":["https://openalex.org/I4210119759","https://openalex.org/I4405270573"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078105649","display_name":"R. Ascherl","orcid":"https://orcid.org/0000-0002-7788-1526","observed_orcids":["https://orcid.org/0000-0002-7788-1526"]},"institutions":[{"id":"https://openalex.org/I9341345","display_name":"University of L\u00fcbeck","ror":"https://ror.org/00t3r8h32","country_code":"DE","type":"education","lineage":["https://openalex.org/I9341345"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Rudolf Ascherl","raw_affiliation_strings":["Departments of Orthopaedic Surgery, Medical University, L\u00fcbeck, Germany, +49 201-7231301, -7235936"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Orthopaedic Surgery, Medical University, L\u00fcbeck, Germany, +49 201-7231301, -7235936","institution_ids":["https://openalex.org/I9341345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112804050","display_name":"G. Bl\u00fcmel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"G\u00fcnther Bl\u00fcmel","raw_affiliation_strings":["Institute for Experimental Surgery, Technical University, Munich, Germany, +49 201 -7231301, -7235936"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Experimental Surgery, Technical University, Munich, Germany, +49 201 -7231301, -7235936","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112727240","display_name":"K. P. Schmit-Neuerburg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Klaus Peter Schmit-neuerburg","raw_affiliation_strings":["Departments of Trauma Surgery, University Clinic, D-45122 Essen, Technical University, Munich, Germany, +49 201-7231301, -7235936"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Trauma Surgery, University Clinic, D-45122 Essen, Technical University, Munich, Germany, +49 201-7231301, -7235936","institution_ids":["https://openalex.org/I62916508"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5189,"has_fulltext":true,"cited_by_count":48,"citation_normalized_percentile":{"value":0.66148038,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"67","issue":"6","first_page":"583","last_page":"588"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10975","display_name":"Bone Tumor Diagnosis and Treatments","score":0.4722000062465668,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10975","display_name":"Bone Tumor Diagnosis and Treatments","score":0.4722000062465668,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10658","display_name":"Bone fractures and treatments","score":0.24500000476837158,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.13439999520778656,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/autologous-bone-graft","display_name":"autologous bone graft","score":0.671999990940094},{"id":"https://openalex.org/keywords/cortical-bone-graft","display_name":"cortical bone graft","score":0.8769999742507935},{"id":"https://openalex.org/keywords/extracorporeal-irradiation","display_name":"extracorporeal irradiation","score":0.9359999895095825},{"id":"https://openalex.org/keywords/graft-incorporation","display_name":"graft integration","score":0.7319999933242798},{"id":"https://openalex.org/keywords/bone-graft-healing","display_name":"bone graft healing","score":0.6589999794960022},{"id":"https://openalex.org/keywords/tibial-diaphysis","display_name":"tibial diaphysis","score":0.7639999985694885},{"id":"https://openalex.org/keywords/bone-tumor-resection","display_name":"bone tumor resection","score":0.6330000162124634},{"id":"https://openalex.org/keywords/radiation-dose-effects","display_name":"radiation dose effects","score":0.4970000088214874},{"id":"https://openalex.org/keywords/allograft-alternatives","display_name":"allograft alternatives","score":0.7139999866485596}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8882393836975098},{"id":"https://openalex.org/C2779915274","wikidata":"https://www.wikidata.org/wiki/Q1115882","display_name":"Extracorporeal","level":2,"score":0.6772654056549072},{"id":"https://openalex.org/C111337013","wikidata":"https://www.wikidata.org/wiki/Q2737837","display_name":"Irradiation","level":2,"score":0.6118665337562561},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5871039032936096},{"id":"https://openalex.org/C2777236700","wikidata":"https://www.wikidata.org/wiki/Q178366","display_name":"Tibia","level":2,"score":0.5648456811904907},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.485573947429657},{"id":"https://openalex.org/C2781451080","wikidata":"https://www.wikidata.org/wiki/Q265868","display_name":"Cortical bone","level":2,"score":0.44906583428382874},{"id":"https://openalex.org/C2777304102","wikidata":"https://www.wikidata.org/wiki/Q1667915","display_name":"Osteosynthesis","level":2,"score":0.42368435859680176},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.21513265371322632},{"id":"https://openalex.org/C185544564","wikidata":"https://www.wikidata.org/wiki/Q81197","display_name":"Nuclear physics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D003037","descriptor_name":"Cobalt Radioisotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011829","descriptor_name":"Radiation Dosage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013977","descriptor_name":"Tibia","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D014182","descriptor_name":"Transplantation, Autologous","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D014945","descriptor_name":"Wound Healing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016025","descriptor_name":"Bone Transplantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D016348","descriptor_name":"Osseointegration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3109/17453679608997761","doi":"https://doi.org/10.3109/17453679608997761","is_oa":false,"landing_page_url":"https://doi.org/10.3109/17453679608997761","pdf_url":null,"source":{"id":"https://openalex.org/S198708498","display_name":"Acta Orthopaedica Scandinavica","issn_l":"0001-6470","issn":["0001-6470"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Orthopaedica Scandinavica","raw_type":"journal-article"},{"id":"pmh:oai:medicaljournalssweden.se:article/21053","doi":null,"is_oa":true,"landing_page_url":"https://actaorthop.org/actao/article/view/21053","pdf_url":"https://actaorthop.org/actao/article/download/21053/24888","source":{"id":"https://openalex.org/S58634475","display_name":"Acta Orthopaedica","issn_l":"1745-3674","issn":["1745-3674","1745-3682"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"1745-3674","raw_type":"info:eu-repo/semantics/article"},{"id":"pmid:9065072","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9065072","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta orthopaedica Scandinavica","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:medicaljournalssweden.se:article/21053","doi":null,"is_oa":true,"landing_page_url":"https://actaorthop.org/actao/article/view/21053","pdf_url":"https://actaorthop.org/actao/article/download/21053/24888","source":{"id":"https://openalex.org/S58634475","display_name":"Acta Orthopaedica","issn_l":"1745-3674","issn":["1745-3674","1745-3682"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"1745-3674","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2012564010.pdf","grobid_xml":"https://content.openalex.org/works/W2012564010.grobid-xml"},"referenced_works_count":14,"referenced_works":["https://openalex.org/W197424539","https://openalex.org/W1723400417","https://openalex.org/W1969393136","https://openalex.org/W1999635061","https://openalex.org/W2023329278","https://openalex.org/W2073308590","https://openalex.org/W2090661238","https://openalex.org/W2112331964","https://openalex.org/W2154131294","https://openalex.org/W2304302908","https://openalex.org/W2395159049","https://openalex.org/W2395266724","https://openalex.org/W2413809786","https://openalex.org/W2885094438"],"related_works":["https://openalex.org/W2123997936","https://openalex.org/W2059940749","https://openalex.org/W2109942516","https://openalex.org/W1976168507","https://openalex.org/W2006678738","https://openalex.org/W3196811773","https://openalex.org/W4322496321","https://openalex.org/W2052974247","https://openalex.org/W2093828769","https://openalex.org/W2001128814"],"abstract_inverted_index":{"The":[0,111,140],"incorporation":[1,141],"of":[2,29,67,85,113,130,138,142,177,186],"resected,":[3,33],"extracorporeally":[4],"irradiated":[5,34,71,109,116,147,171],"(1,":[6],"5,":[7],"25":[8,114],"and":[9,12,35,52,59,75,91,104,125,144,168,184],"50":[10,69],"kGy)":[11,153,157],"orthotopically":[13],"reimplanted":[14,36],"autogeneic":[15,164,172],"cortical":[16],"bone":[17,173,187],"was":[18,48,82,118],"investigated":[19],"in":[20],"116":[21],"adult":[22],"Wistar":[23],"rats.":[24],"7":[25],"mm-long":[26],"diaphyseal":[27],"segments":[28],"the":[30,68,77,101,121,128,131],"tibia":[31],"were":[32,73,95],"using":[37],"K-wire":[38],"osteosynthesis.":[39],"Autogeneic":[40],"fresh":[41,165],"grafts":[42,72,117,148,174],"served":[43],"as":[44],"controls.":[45],"Graft":[46],"healing":[47,112],"evaluated":[49],"by":[50],"radiography":[51],"histomorphometric":[53],"study":[54],"at":[55,133,159],"3,":[56],"6,":[57],"9,":[58],"12":[60,134,160],"weeks.":[61],"At":[62],"3":[63,90],"weeks,":[64,161],"two":[65],"thirds":[66],"kGy":[70,108,115,146,170],"fractured":[74],"therefore":[76,190],"series":[78],"with":[79],"this":[80],"dose":[81],"interrupted":[83],"because":[84],"mechanical":[86],"graft":[87],"insufficiency.":[88],"After":[89],"6":[92],"weeks":[93,135],"there":[94],"no":[96],"statistically":[97],"significant":[98],"differences":[99],"among":[100],"control":[102],"group":[103],"1":[105,143,167],"or":[106],"5":[107,145,169],"grafts.":[110,166],"delayed":[119],"from":[120],"sixth":[122],"week":[123],"onwards":[124],"continued":[126],"until":[127],"end":[129],"experiment":[132],"(50%":[136],"reduction":[137],"incorporation).":[139],"showed":[149],"a":[150,192],"16%":[151],"(1":[152],"to":[154,163,195],"24%":[155],"(5":[156],"delay":[158],"compared":[162],"retain":[175],"most":[176],"their":[178],"biological":[179],"potential.":[180],"Resection,":[181],"extracorporeal":[182],"irradiation":[183],"reimplantation":[185],"tumors":[188],"may":[189],"be":[191],"possible":[193],"alternative":[194],"allografting.":[196]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}