{"id":"https://openalex.org/W2012525852","doi":"https://doi.org/10.1080/08820130902984828","title":"Allotransplantation of Sulphate Glucomannan-Alginate Barium (SGA)-Microencapsulated Rat Islets for the Treatment of Diabetes Mellitus","display_name":"Allotransplantation of Sulphate Glucomannan-Alginate Barium (SGA)-Microencapsulated Rat Islets for the Treatment of Diabetes Mellitus","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W2012525852","doi":"https://doi.org/10.1080/08820130902984828","mag":"2012525852","pmid":"https://pubmed.ncbi.nlm.nih.gov/19811421"},"language":"en","primary_location":{"id":"doi:10.1080/08820130902984828","doi":"https://doi.org/10.1080/08820130902984828","is_oa":false,"landing_page_url":"https://doi.org/10.1080/08820130902984828","pdf_url":null,"source":{"id":"https://openalex.org/S44471553","display_name":"Immunological Investigations","issn_l":"0882-0139","issn":["0882-0139","1532-4311"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunological Investigations","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100329932","display_name":"Xi Chen","orcid":"https://orcid.org/0000-0002-3160-614X","observed_orcids":["https://orcid.org/0000-0002-3160-614X"]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I4210132813","display_name":"Second Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/03s8txj32","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210132813"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xi Chen","raw_affiliation_strings":["Dept of Surgery, Second Affiliated Hospital, Harbin Medical University, Harbin, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept of Surgery, Second Affiliated Hospital, Harbin Medical University, Harbin, PR China","institution_ids":["https://openalex.org/I156144747","https://openalex.org/I4210132813"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023604056","display_name":"Wei Shao","orcid":"https://orcid.org/0000-0003-1763-9911","observed_orcids":["https://orcid.org/0000-0003-1763-9911"]},"institutions":[{"id":"https://openalex.org/I191208505","display_name":"Xiamen University","ror":"https://ror.org/00mcjh785","country_code":"CN","type":"education","lineage":["https://openalex.org/I191208505"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Shao","raw_affiliation_strings":["Organ Transplantation Institute, Xiamen University, Xiamen, P. R China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Organ Transplantation Institute, Xiamen University, Xiamen, P. R China","institution_ids":["https://openalex.org/I191208505"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022681647","display_name":"Jibing Chen","orcid":"https://orcid.org/0000-0001-8596-2126","observed_orcids":["https://orcid.org/0000-0001-8596-2126"]},"institutions":[{"id":"https://openalex.org/I191208505","display_name":"Xiamen University","ror":"https://ror.org/00mcjh785","country_code":"CN","type":"education","lineage":["https://openalex.org/I191208505"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ji-bing Chen","raw_affiliation_strings":["Organ Transplantation Institute, Xiamen University, Xiamen, P. R China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Organ Transplantation Institute, Xiamen University, Xiamen, P. R China","institution_ids":["https://openalex.org/I191208505"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101691764","display_name":"Lei Zhang","orcid":"https://orcid.org/0009-0003-1693-0093","observed_orcids":["https://orcid.org/0009-0003-1693-0093"]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I4210132813","display_name":"Second Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/03s8txj32","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210132813"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lei Zhang","raw_affiliation_strings":["Dept of Surgery, Second Affiliated Hospital, Harbin Medical University, Harbin, P. R China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept of Surgery, Second Affiliated Hospital, Harbin Medical University, Harbin, P. R China","institution_ids":["https://openalex.org/I156144747","https://openalex.org/I4210132813"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052764346","display_name":"Matthias Corbascio","orcid":"https://orcid.org/0000-0003-3544-6689","observed_orcids":["https://orcid.org/0000-0003-3544-6689"]},"institutions":[{"id":"https://openalex.org/I1335113835","display_name":"Karolinska University Hospital","ror":"https://ror.org/00m8d6786","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I1335113835"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Corbascio Matthias","raw_affiliation_strings":["Dept of Cardiothoracic Surgery and Anesthesiology, Karolinska University Hospital, Solna, Karolinska Institute, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept of Cardiothoracic Surgery and Anesthesiology, Karolinska University Hospital, Solna, Karolinska Institute, Stockholm, Sweden","institution_ids":["https://openalex.org/I1335113835","https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008895479","display_name":"Shi-guang Shan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]},{"id":"https://openalex.org/I4210132813","display_name":"Second Affiliated Hospital of Harbin Medical University","ror":"https://ror.org/03s8txj32","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210132813"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shi-guang Shan","raw_affiliation_strings":["Dept of Surgery, Second Affiliated Hospital, Harbin Medical University, Harbin, P. R China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept of Surgery, Second Affiliated Hospital, Harbin Medical University, Harbin, P. R China","institution_ids":["https://openalex.org/I156144747","https://openalex.org/I4210132813"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100627047","display_name":"Zhongquan Qi","orcid":"https://orcid.org/0000-0002-7210-4955","observed_orcids":["https://orcid.org/0000-0002-7210-4955"]},"institutions":[{"id":"https://openalex.org/I191208505","display_name":"Xiamen University","ror":"https://ror.org/00mcjh785","country_code":"CN","type":"education","lineage":["https://openalex.org/I191208505"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhong-quan Qi","raw_affiliation_strings":["Organ Transplantation Institute, Xiamen University, Xiamen, P. R China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Organ Transplantation Institute, Xiamen University, Xiamen, P. R China","institution_ids":["https://openalex.org/I191208505"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5100627047"],"corresponding_institution_ids":["https://openalex.org/I191208505"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.15357562,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"38","issue":"7","first_page":"561","last_page":"571"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11171","display_name":"Diabetes and associated disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/islet-microencapsulation","display_name":"islet microencapsulation","score":0.8320000171661377},{"id":"https://openalex.org/keywords/allogeneic-islet-transplantation","display_name":"allogeneic islet transplantation","score":0.777999997138977},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.7820000052452087},{"id":"https://openalex.org/keywords/insulin-secretion","display_name":"insulin secretion","score":0.7440000176429749},{"id":"https://openalex.org/keywords/cytokine-production","display_name":"cytokine production","score":0.9190000295639038},{"id":"https://openalex.org/keywords/inflammatory-cell-infiltration","display_name":"inflammatory cell infiltration","score":0.8550000190734863},{"id":"https://openalex.org/keywords/normoglycemia","display_name":"normoglycemia","score":0.8899999856948853},{"id":"https://openalex.org/keywords/islet-transplantation","display_name":"islet transplantation","score":0.47600001096725464}],"concepts":[{"id":"https://openalex.org/C165220095","wikidata":"https://www.wikidata.org/wiki/Q207524","display_name":"Islet","level":3,"score":0.732491135597229},{"id":"https://openalex.org/C2777561873","wikidata":"https://www.wikidata.org/wiki/Q1773075","display_name":"Allotransplantation","level":3,"score":0.6925818920135498},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5802690982818604},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.5270119905471802},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.523250937461853},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5205772519111633},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5190873146057129},{"id":"https://openalex.org/C2779855799","wikidata":"https://www.wikidata.org/wiki/Q728309","display_name":"Pancreatic islets","level":4,"score":0.45772039890289307},{"id":"https://openalex.org/C2780179618","wikidata":"https://www.wikidata.org/wiki/Q902534","display_name":"Glucomannan","level":2,"score":0.45579323172569275},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.4411427676677704},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.43921688199043274},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.33618780970573425},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.27006757259368896},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.26265472173690796}],"mesh":[{"descriptor_ui":"D000464","descriptor_name":"Alginates","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001466","descriptor_name":"Barium Sulfate","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003921","descriptor_name":"Diabetes Mellitus, Experimental","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003921","descriptor_name":"Diabetes Mellitus, Experimental","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006603","descriptor_name":"Hexuronic Acids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007371","descriptor_name":"Interferon-gamma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007375","descriptor_name":"Interleukin-1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007515","descriptor_name":"Islets of Langerhans","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007515","descriptor_name":"Islets of Langerhans","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008351","descriptor_name":"Mannans","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008863","descriptor_name":"Microspheres","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011107","descriptor_name":"Polylysine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D011107","descriptor_name":"Polylysine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011917","descriptor_name":"Rats, Inbred Lew","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014184","descriptor_name":"Transplantation, Homologous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016381","descriptor_name":"Islets of Langerhans Transplantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018932","descriptor_name":"Chemokine CCL2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020723","descriptor_name":"Glucuronic Acid","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1080/08820130902984828","doi":"https://doi.org/10.1080/08820130902984828","is_oa":false,"landing_page_url":"https://doi.org/10.1080/08820130902984828","pdf_url":null,"source":{"id":"https://openalex.org/S44471553","display_name":"Immunological Investigations","issn_l":"0882-0139","issn":["0882-0139","1532-4311"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunological Investigations","raw_type":"journal-article"},{"id":"pmid:19811421","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19811421","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunological investigations","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320323085","display_name":"Natural Science Foundation of Heilongjiang Province","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W2022282748","https://openalex.org/W2037857020","https://openalex.org/W2046016102","https://openalex.org/W2050850786","https://openalex.org/W2078877235","https://openalex.org/W2098899709","https://openalex.org/W2108371710","https://openalex.org/W2112773576","https://openalex.org/W2133186034","https://openalex.org/W2146870193","https://openalex.org/W2154806185","https://openalex.org/W2328786770","https://openalex.org/W2416319624","https://openalex.org/W2432268344"],"related_works":["https://openalex.org/W1987392828","https://openalex.org/W2347890311","https://openalex.org/W2367443253","https://openalex.org/W2363208480","https://openalex.org/W2433275453","https://openalex.org/W2387597671","https://openalex.org/W354003612","https://openalex.org/W942245124","https://openalex.org/W2353438809","https://openalex.org/W2352105020"],"abstract_inverted_index":{"To":[0,59],"offer":[1],"a":[2,17],"more":[3,111],"effective":[4],"microencapsulation":[5],"technique":[6],"of":[7,12,20,43,87,91,139,156],"islets":[8,45,74,93,105,119,168],"for":[9,125,177],"the":[10,73,85,88,102,114,128,133,142,149,154,160,164],"treatment":[11],"diabetes,":[13],"we":[14,53],"have":[15],"developed":[16],"new":[18],"type":[19],"microcapsule":[21],"comprising":[22],"sulphate":[23],"glucomannan-alginate":[24],"barium":[25],"(SGA).":[26],"We":[27],"compared":[28],"it":[29],"with":[30],"traditional":[31],"microencapsulated":[32,38,44,92,104,118,167,183],"APA":[33,115,180],"(alginate-poly-L-lysine-alginate)":[34],"and":[35,48,52,57,66,109,116,181],"ABa":[36,117,182],"(Ba(2+)-alginate)":[37],"islets.":[39,184],"These":[40],"three":[41,89],"types":[42,90],"were":[46,75,145],"prepared":[47],"cultured":[49],"in":[50,84,99,127,132,141,148,172],"vitro":[51],"studied":[54],"their":[55,61,95],"morphology":[56],"activity.":[58],"determine":[60],"effects":[62],"on":[63],"insulin":[64,96,112],"secretion":[65],"cytokine":[67],"production":[68],"(MCP-1,":[69],"IL-1,":[70],"IFN-gamma,":[71],"TNF-alpha)":[72],"transplanted":[76],"into":[77],"diabetic":[78,173],"rats.":[79],"There":[80],"was":[81,123,153],"no":[82],"difference":[83],"morphologies":[86],"or":[94],"secretory":[97],"capacity":[98],"vitro.":[100],"However,":[101],"SGA":[103,150,166],"had":[106],"higher":[107],"activity":[108],"produced":[110],"than":[113,131,179],"after":[120],"transplantation.":[121],"Normoglycemia":[122],"maintained":[124],"longer":[126,178],"SGA-transplanted":[129],"group":[130],"other":[134],"two":[135],"groups.":[136],"The":[137],"concentrations":[138],"cytokines":[140],"peritoneal":[143],"fluid":[144],"significantly":[146],"decreased":[147],"group,":[151],"as":[152],"infiltration":[155],"inflammatory":[157],"cells":[158],"around":[159],"microcapsules.":[161],"In":[162],"conclusion,":[163],"novel":[165],"can":[169],"maintain":[170],"normoglycemia":[171],"rats":[174],"without":[175],"immunosuppression":[176]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}