{"id":"https://openalex.org/W2012520740","doi":"https://doi.org/10.1001/jama.1973.03220020064039","title":"Multiple Sclerosis: Immunology, Virology, and Ultrastructure","display_name":"Multiple Sclerosis: Immunology, Virology, and Ultrastructure","publication_year":1973,"publication_date":"1973-01-08","ids":{"openalex":"https://openalex.org/W2012520740","doi":"https://doi.org/10.1001/jama.1973.03220020064039","mag":"2012520740"},"language":"en","primary_location":{"id":"doi:10.1001/jama.1973.03220020064039","doi":"https://doi.org/10.1001/jama.1973.03220020064039","is_oa":false,"landing_page_url":"https://doi.org/10.1001/jama.1973.03220020064039","pdf_url":null,"source":{"id":"https://openalex.org/S172573765","display_name":"JAMA","issn_l":"0002-9955","issn":["0002-9955","0098-7484","1538-3598","2376-8118"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA: The Journal of the American Medical Association","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055807956","display_name":"Frank R. Freemon","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Frank R. Freemon","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5055807956"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":16.5531,"has_fulltext":false,"cited_by_count":108,"citation_normalized_percentile":{"value":0.99506092,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":"223","issue":"2","first_page":"198","last_page":"198"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11827","display_name":"Polyomavirus and related diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11112","display_name":"Viral Infections and Immunology Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiple-sclerosis","display_name":"multiple sclerosis","score":1.0},{"id":"https://openalex.org/keywords/immunology","display_name":"immunology","score":0.796999990940094},{"id":"https://openalex.org/keywords/virology","display_name":"virology","score":0.9810000061988831},{"id":"https://openalex.org/keywords/ultrastructure","display_name":"ultrastructure","score":0.9750000238418579},{"id":"https://openalex.org/keywords/animal-models-of-multiple-sclerosis","display_name":"animal models of multiple sclerosis","score":0.8820000290870667},{"id":"https://openalex.org/keywords/childhood-onset","display_name":"childhood onset","score":0.47999998927116394}],"concepts":[{"id":"https://openalex.org/C2777869424","wikidata":"https://www.wikidata.org/wiki/Q978185","display_name":"TypeScript","level":2,"score":0.8982208967208862},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.639974057674408},{"id":"https://openalex.org/C2780640218","wikidata":"https://www.wikidata.org/wiki/Q8277","display_name":"Multiple sclerosis","level":2,"score":0.6193556785583496},{"id":"https://openalex.org/C554936623","wikidata":"https://www.wikidata.org/wiki/Q199657","display_name":"Reading (process)","level":2,"score":0.5736867785453796},{"id":"https://openalex.org/C122980154","wikidata":"https://www.wikidata.org/wiki/Q205555","display_name":"Feeling","level":2,"score":0.4962676167488098},{"id":"https://openalex.org/C52119013","wikidata":"https://www.wikidata.org/wiki/Q50637","display_name":"Art history","level":1,"score":0.25957369804382324},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.2394842803478241},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.22113922238349915},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2069159746170044},{"id":"https://openalex.org/C95457728","wikidata":"https://www.wikidata.org/wiki/Q309","display_name":"History","level":0,"score":0.1662449836730957},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1001/jama.1973.03220020064039","doi":"https://doi.org/10.1001/jama.1973.03220020064039","is_oa":false,"landing_page_url":"https://doi.org/10.1001/jama.1973.03220020064039","pdf_url":null,"source":{"id":"https://openalex.org/S172573765","display_name":"JAMA","issn_l":"0002-9955","issn":["0002-9955","0098-7484","1538-3598","2376-8118"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA: The Journal of the American Medical Association","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1965538421","https://openalex.org/W1997994346","https://openalex.org/W4242548767","https://openalex.org/W1997987836","https://openalex.org/W2058269387","https://openalex.org/W2326954558","https://openalex.org/W2045007190","https://openalex.org/W2048697201","https://openalex.org/W2527092858","https://openalex.org/W161295041"],"abstract_inverted_index":{"Despite":[0],"tantalizing":[1],"immunologic":[2],"and":[3,35,49,75,97,148],"epidemiologic":[4],"clues,":[5],"real":[6],"progress":[7],"in":[8,23,42,94,133,144],"understanding":[9],"multiple":[10,33,121,140],"sclerosis":[11,34,122,141],"eludes":[12],"us.":[13],"Many":[14],"American":[15],"research":[16,30,123,129],"workers":[17],"gathered":[18,78],"at":[19,79],"a":[20,63,116,120],"California":[21],"ranch":[22],"February":[24],"1972":[25],"to":[26,72,91],"consider":[27],"some":[28],"recent":[29],"results":[31,93],"concerning":[32],"its":[36],"animal":[37],"models.":[38],"This":[39],"book":[40],"reproduces":[41],"typescript":[43],"form":[44],"the":[45,50,80,106,110],"invited":[46],"technical":[47,53],"papers":[48],"even":[51],"more":[52],"discussions.":[54],"Typescript":[55],"printing":[56],"techniques":[57],"allow":[58],"rapid":[59],"publication":[60],"but":[61],"produce":[62],"page":[64],"with":[65],"uneven":[66],"righthand":[67],"margins,":[68],"which":[69],"is":[70,114,142],"difficult":[71],"read.":[73],"Figures":[74],"tables":[76],"are":[77,102,131],"end":[81],"of":[82,128],"each":[83],"chapter":[84],"rather":[85],"than":[86],"interspersed":[87],"throughout.":[88],"The":[89],"rush":[90],"press":[92],"many":[95],"typographical":[96],"grammatical":[98],"errors.":[99],"These":[100],"contributions":[101],"so":[103],"unpolished":[104],"that":[105,112,139],"reader":[107],"may":[108],"get":[109],"feeling":[111],"he":[113],"reading":[115],"typed":[117],"manuscript":[118],"from":[119],"worker.":[124],"Several":[125],"separate":[126],"lines":[127],"endeavor":[130],"reviewed":[132],"this":[134],"book.":[135],"Epidemiologic":[136],"studies":[137],"suggest":[138],"acquired":[143],"childhood":[145],"or":[146],"adolescence":[147],"several":[149]},"counts_by_year":[],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}