{"id":"https://openalex.org/W2012504033","doi":"https://doi.org/10.1371/journal.pntd.0001702","title":"Comparing the Clinical and Histological Diagnosis of Leprosy and Leprosy Reactions in the INFIR Cohort of Indian Patients with Multibacillary Leprosy","display_name":"Comparing the Clinical and Histological Diagnosis of Leprosy and Leprosy Reactions in the INFIR Cohort of Indian Patients with Multibacillary Leprosy","publication_year":2012,"publication_date":"2012-06-26","ids":{"openalex":"https://openalex.org/W2012504033","doi":"https://doi.org/10.1371/journal.pntd.0001702","mag":"2012504033","pmid":"https://pubmed.ncbi.nlm.nih.gov/22745841","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3383736"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pntd.0001702","doi":"https://doi.org/10.1371/journal.pntd.0001702","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pntd.0001702","pdf_url":"https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0001702&type=printable","source":{"id":"https://openalex.org/S46544255","display_name":"PLoS neglected tropical diseases","issn_l":"1935-2727","issn":["1935-2727","1935-2735"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Neglected Tropical Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0001702&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042870699","display_name":"Diana N. J. Lockwood","orcid":"https://orcid.org/0000-0003-2865-8966","observed_orcids":["https://orcid.org/0000-0003-2865-8966"]},"institutions":[{"id":"https://openalex.org/I4210089966","display_name":"London School of Hygiene & Tropical Medicine","ror":"https://ror.org/00a0jsq62","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210089966"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Diana N. J. Lockwood","raw_affiliation_strings":["Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom. Diana.Lockwood@lshtm.ac.uk","Faculty of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom. Diana.Lockwood@lshtm.ac.uk","institution_ids":["https://openalex.org/I4210089966"]},{"raw_affiliation_string":"Faculty of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom","institution_ids":["https://openalex.org/I4210089966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007115319","display_name":"PETER G. NICHOLLS","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Peter Nicholls","raw_affiliation_strings":["School of Health Sciences, University of Southampton, Southampton, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Health Sciences, University of Southampton, Southampton, United Kingdom","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108395098","display_name":"W. C. S. Smith","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I195460627","display_name":"University of Aberdeen","ror":"https://ror.org/016476m91","country_code":"GB","type":"education","lineage":["https://openalex.org/I195460627"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"W. Cairns S. Smith","raw_affiliation_strings":["School of Public Health, University of Aberdeen, Aberdeen, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Public Health, University of Aberdeen, Aberdeen, United Kingdom","institution_ids":["https://openalex.org/I195460627"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033813640","display_name":"Loretta Das","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405267752","display_name":"The Leprosy Mission Trust India","ror":"https://ror.org/046a6pa59","country_code":"IN","type":"nonprofit","lineage":["https://openalex.org/I4405267752"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Loretta Das","raw_affiliation_strings":["The Leprosy Mission Trust, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Leprosy Mission Trust, New Delhi, India","institution_ids":["https://openalex.org/I4405267752"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074429698","display_name":"Pramila Barkataki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405267752","display_name":"The Leprosy Mission Trust India","ror":"https://ror.org/046a6pa59","country_code":"IN","type":"nonprofit","lineage":["https://openalex.org/I4405267752"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Pramila Barkataki","raw_affiliation_strings":["The Leprosy Mission Trust, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Leprosy Mission Trust, New Delhi, India","institution_ids":["https://openalex.org/I4405267752"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082007863","display_name":"Wim H. van Brakel","orcid":"https://orcid.org/0000-0002-3421-4686","observed_orcids":["https://orcid.org/0000-0002-3421-4686"]},"institutions":[{"id":"https://openalex.org/I2800512269","display_name":"Royal Tropical Institute","ror":"https://ror.org/01z6bgg93","country_code":"NL","type":"archive","lineage":["https://openalex.org/I2800512269"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Wim van Brakel","raw_affiliation_strings":["Leprosy Unit, Royal Tropical Institute, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Leprosy Unit, Royal Tropical Institute, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I2800512269"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110719605","display_name":"Sujai K. Suneetha","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sujai Suneetha","raw_affiliation_strings":["Blue Peter Research Centre, Hyderabad, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blue Peter Research Centre, Hyderabad, India","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5042870699"],"corresponding_institution_ids":["https://openalex.org/I4210089966"],"apc_list":{"value":2670,"currency":"USD","value_usd":2670},"apc_paid":{"value":2670,"currency":"USD","value_usd":2670},"fwci":2.9009,"has_fulltext":true,"cited_by_count":65,"citation_normalized_percentile":{"value":0.89788694,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"6","issue":"6","first_page":"e1702","last_page":"e1702"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12107","display_name":"Leprosy Research and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12107","display_name":"Leprosy Research and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10823","display_name":"Research on Leishmaniasis Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11934","display_name":"Syphilis Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/leprosy-reactions","display_name":"leprosy reactions","score":0.8199999928474426},{"id":"https://openalex.org/keywords/multibacillary-leprosy","display_name":"multibacillary leprosy","score":0.9480000138282776},{"id":"https://openalex.org/keywords/type-1-reaction","display_name":"type 1 reaction","score":0.7179999947547913},{"id":"https://openalex.org/keywords/erythema-nodosum-leprosum","display_name":"erythema nodosum leprosum","score":0.9860000014305115},{"id":"https://openalex.org/keywords/borderline-tuberculoid-leprosy","display_name":"borderline tuberculoid leprosy","score":0.8339999914169312},{"id":"https://openalex.org/keywords/borderline-lepromatous-leprosy","display_name":"borderline lepromatous leprosy","score":0.9990000128746033},{"id":"https://openalex.org/keywords/lepromatous-leprosy","display_name":"lepromatous leprosy","score":0.8379999995231628},{"id":"https://openalex.org/keywords/nerve-function-impairment","display_name":"nerve function impairment","score":0.7160000205039978},{"id":"https://openalex.org/keywords/skin-biopsy-histopathology","display_name":"skin biopsy histopathology","score":0.7379999756813049},{"id":"https://openalex.org/keywords/diagnostic-accuracy","display_name":"diagnostic accuracy","score":0.7289999723434448}],"concepts":[{"id":"https://openalex.org/C2780695269","wikidata":"https://www.wikidata.org/wiki/Q36956","display_name":"Leprosy","level":2,"score":0.9859365224838257},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6968187093734741},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5742441415786743},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.5455668568611145},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.4100199341773987},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3582732677459717}],"mesh":[{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007194","descriptor_name":"India","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010338","descriptor_name":"Pathology, Clinical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015510","descriptor_name":"Clinical Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D056006","descriptor_name":"Leprosy, Multibacillary","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D056006","descriptor_name":"Leprosy, Multibacillary","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":12,"locations":[{"id":"doi:10.1371/journal.pntd.0001702","doi":"https://doi.org/10.1371/journal.pntd.0001702","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pntd.0001702","pdf_url":"https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0001702&type=printable","source":{"id":"https://openalex.org/S46544255","display_name":"PLoS neglected tropical diseases","issn_l":"1935-2727","issn":["1935-2727","1935-2735"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Neglected Tropical Diseases","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2388276","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3383736","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:22745841","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22745841","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS neglected tropical diseases","raw_type":"Evaluation Study"},{"id":"pmh:oai:pubmedcentral.nih.gov:3383736","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3383736/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Negl Trop Dis","raw_type":"Text"},{"id":"pmh:oai:research.vu.nl:openaire/4de2f9a4-6758-475c-b463-2f79de1feaa3","doi":null,"is_oa":true,"landing_page_url":"https://research.vu.nl/en/publications/4de2f9a4-6758-475c-b463-2f79de1feaa3","pdf_url":"https://research.vu.nl/ws/files/703531/303854.pdf","source":{"id":"https://openalex.org/S4306401107","display_name":"VU Research Portal","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I865915315","host_organization_name":"Vrije Universiteit Amsterdam","host_organization_lineage":["https://openalex.org/I865915315"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Lockwood, D N J, Nicholls, P, Smith, W C S, Das, L, Barkataki, P, van Brakel, W H & Suneetha, S 2012, 'Comparing the clinical and histological diagnosis of leprosy and leprosy reactions in the infir cohort of indian patients with multibacillary leprosy', PLoS Neglected Tropical Diseases, vol. 6, no. 6. https://doi.org/10.1371/journal.pntd.0001702","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:researchonline.lshtm.ac.uk:39817","doi":null,"is_oa":false,"landing_page_url":"https://researchonline.lshtm.ac.uk/view/creators/icrudloc.html>;","pdf_url":null,"source":{"id":"https://openalex.org/S4306402527","display_name":"LSHTM Research Online (London School of Hygiene and Tropical Medicine)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210089966","host_organization_name":"London School of Hygiene & Tropical Medicine","host_organization_lineage":["https://openalex.org/I4210089966"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.787.8246","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.787.8246","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/cd/af/pntd.0001702.PMC3383736.pdf","raw_type":"text"},{"id":"pmh:oai:dare.ubvu.vu.nl:1871/48802","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1871/48802","pdf_url":null,"source":{"id":"https://openalex.org/S4306400546","display_name":"Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I865915315","host_organization_name":"Vrije Universiteit Amsterdam","host_organization_lineage":["https://openalex.org/I865915315"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"6","raw_type":"Article / Letter to editor"},{"id":"pmh:oai:doaj.org/article:60ddf0ce34664317be5d322e2b4e14da","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/60ddf0ce34664317be5d322e2b4e14da","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Neglected Tropical Diseases, Vol 6, Iss 6, p e1702 (2012)","raw_type":"article"},{"id":"pmh:vu:oai:research.vu.nl:publications/4de2f9a4-6758-475c-b463-2f79de1feaa3","doi":null,"is_oa":true,"landing_page_url":"https://research.vu.nl/en/publications/4de2f9a4-6758-475c-b463-2f79de1feaa3","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Neglected Tropical Diseases, 6(6). Public Library of Science","raw_type":"info:eu-repo/semantics/article"},{"id":"doi:10.60692/6g2p9-hnp89","doi":"https://doi.org/10.60692/6g2p9-hnp89","is_oa":true,"landing_page_url":"https://doi.org/10.60692/6g2p9-hnp89","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"},{"id":"doi:10.60692/8wz8d-09d50","doi":"https://doi.org/10.60692/8wz8d-09d50","is_oa":true,"landing_page_url":"https://doi.org/10.60692/8wz8d-09d50","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1371/journal.pntd.0001702","doi":"https://doi.org/10.1371/journal.pntd.0001702","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pntd.0001702","pdf_url":"https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0001702&type=printable","source":{"id":"https://openalex.org/S46544255","display_name":"PLoS neglected tropical diseases","issn_l":"1935-2727","issn":["1935-2727","1935-2735"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Neglected Tropical Diseases","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320279","display_name":"University of Warwick","ror":"https://ror.org/01a77tt86"},{"id":"https://openalex.org/F4320323507","display_name":"Christian Medical College, Vellore","ror":"https://ror.org/00c7kvd80"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2012504033.pdf","grobid_xml":"https://content.openalex.org/works/W2012504033.grobid-xml"},"referenced_works_count":22,"referenced_works":["https://openalex.org/W81712004","https://openalex.org/W184485255","https://openalex.org/W288518295","https://openalex.org/W1482217310","https://openalex.org/W1592233687","https://openalex.org/W1605538900","https://openalex.org/W1873330124","https://openalex.org/W2057796945","https://openalex.org/W2119571471","https://openalex.org/W2138386305","https://openalex.org/W2144894592","https://openalex.org/W2152305969","https://openalex.org/W2158701076","https://openalex.org/W2162446333","https://openalex.org/W2290751008","https://openalex.org/W2310111717","https://openalex.org/W2401793899","https://openalex.org/W2403207875","https://openalex.org/W2414170434","https://openalex.org/W2620844555","https://openalex.org/W3206486718","https://openalex.org/W4291677065"],"related_works":["https://openalex.org/W2410754570","https://openalex.org/W2144894592","https://openalex.org/W2770945023","https://openalex.org/W6948998328","https://openalex.org/W3080619950","https://openalex.org/W2069518376","https://openalex.org/W2131052976","https://openalex.org/W3049331097","https://openalex.org/W2898267625","https://openalex.org/W2528525004"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,25,93,171,209],"ILEP":[2],"Nerve":[3],"Function":[4],"Impairment":[5],"in":[6,23,57,61,103,121,201,206,274],"Reaction":[7],"(INFIR)":[8],"is":[9,239],"a":[10,72,138,147],"cohort":[11],"study":[12,29],"designed":[13],"to":[14,28,75,254],"identify":[15],"predictors":[16],"of":[17,36,82,90,105,112,142,144,151,175,212,277],"reactions":[18,85,114,120,143,262],"and":[19,33,42,86,124,128,146,162,168,173,182,187,189,228,242,249,268,286,288],"nerve":[20,129],"function":[21],"impairment":[22],"leprosy.":[24],"aim":[26],"was":[27,180,198,217],"correlations":[30],"between":[31],"clinical":[32,139,161,176,294],"histological":[34,80,148,163],"diagnosis":[35,81,140,149,164,177,276],"reactions.":[37,278],"METHODOLOGY/PRINCIPAL":[38],"FINDINGS:":[39],"Three":[40],"hundred":[41],"three":[43],"newly":[44],"diagnosed":[45,95,117,199],"patients":[46,109,123,154,186,203,213,244,255],"with":[47,126,132,155,230,245,256],"World":[48],"Health":[49],"Organization":[50],"multibacillary":[51],"(MB)":[52],"leprosy":[53,84,136,159],"from":[54,108],"two":[55,202],"centres":[56],"India":[58],"were":[59,69,166],"enrolled":[60],"the":[62,79,87,91,160,275],"study.":[63],"Skin":[64],"biopsies":[65,107],"taken":[66],"at":[67,110,283],"enrolment":[68],"assessed":[70],"using":[71],"standardised":[73],"proforma":[74],"collect":[76],"data":[77,234],"on":[78,293],"leprosy,":[83],"certainty":[88],"level":[89],"diagnosis.":[92],"pathologist":[94],"definite":[96],"or":[97],"probable":[98],"Type":[99],"1":[100],"Reactions":[101],"(T1R)":[102],"113":[104],"265":[106],"risk":[111],"developing":[113],"whereas":[115],"clinicians":[116,267],"skin":[118,127],"only":[119],"39":[122],"19":[125],"involvement.":[130],"Patients":[131],"Borderline":[133,156],"Tuberculoid":[134],"(BT)":[135],"had":[137],"rate":[141,150],"43%":[145],"61%;":[152],"for":[153,178,184,191],"Lepromatous":[157,223],"(BL)":[158],"rates":[165,271],"53.7%":[167],"46.2%":[169],"respectively.":[170],"sensitivity":[172],"specificity":[174],"T1R":[179,285],"53.1%":[181],"61.9%":[183],"BT":[185],"61.1%":[188],"71.0%":[190],"BL":[192],"patients.":[193,208],"Erythema":[194],"Nodosum":[195],"Leprosum":[196],"(ENL)":[197],"clinically":[200],"but":[204],"histologically":[205],"13":[207],"Ridley-Jopling":[210],"classification":[211,238],"(n":[214],"=":[215],"303)":[216],"42.8%":[218],"BT,":[219],"27.4%":[220],"BL,":[221],"9.4%":[222],"Leprosy":[224,261],"(LL),":[225],"13.0%":[226],"Indeterminate":[227],"7.4%":[229],"non-specific":[231],"inflammation.":[232],"This":[233],"shows":[235],"that":[236],"MB":[237],"very":[240],"heterogeneous":[241],"encompasses":[243],"no":[246],"detectable":[247],"bacteria":[248],"high":[250,257],"immunological":[251],"activity":[252],"through":[253],"bacterial":[258],"loads.":[259],"CONCLUSIONS/SIGNIFICANCE:":[260],"may":[263],"be":[264],"under-diagnosed":[265],"by":[266],"increasing":[269],"biopsy":[270],"would":[272],"help":[273],"Future":[279],"studies":[280],"should":[281],"look":[282],"sub-clinical":[284],"ENL":[287],"whether":[289],"they":[290],"have":[291],"impact":[292],"outcomes.":[295]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":5}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}