{"id":"https://openalex.org/W2012389967","doi":"https://doi.org/10.2337/diacare.24.4.753","title":"TNFRSF1Bin Genetic Predisposition to Clinical Neuropathy and Effect on HDL Cholesterol and Glycosylated Hemoglobin in Type 2 Diabetes","display_name":"TNFRSF1Bin Genetic Predisposition to Clinical Neuropathy and Effect on HDL Cholesterol and Glycosylated Hemoglobin in Type 2 Diabetes","publication_year":2001,"publication_date":"2001-04-01","ids":{"openalex":"https://openalex.org/W2012389967","doi":"https://doi.org/10.2337/diacare.24.4.753","mag":"2012389967","pmid":"https://pubmed.ncbi.nlm.nih.gov/11315843"},"language":"en","primary_location":{"id":"doi:10.2337/diacare.24.4.753","doi":"https://doi.org/10.2337/diacare.24.4.753","is_oa":true,"landing_page_url":"https://doi.org/10.2337/diacare.24.4.753","pdf_url":"https://diabetesjournals.org/care/article-pdf/24/4/753/588084/753.pdf","source":{"id":"https://openalex.org/S49878492","display_name":"Diabetes Care","issn_l":"0149-5992","issn":["0149-5992","1935-5548"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320274","host_organization_name":"American Diabetes Association","host_organization_lineage":["https://openalex.org/P4310320274"],"host_organization_lineage_names":["American Diabetes Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Care","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://diabetesjournals.org/care/article-pdf/24/4/753/588084/753.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027730127","display_name":"Adam Benjafield","orcid":"https://orcid.org/0000-0003-4716-2827","observed_orcids":["https://orcid.org/0000-0003-4716-2827"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Adam V. Benjafield","raw_affiliation_strings":["Basic Clinical Genomics Laboratory, Department of Physiology and Institute for Biomedical Research, the University of Sydney, Sydney, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Basic Clinical Genomics Laboratory, Department of Physiology and Institute for Biomedical Research, the University of Sydney, Sydney, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021564592","display_name":"Cheryl L. Glenn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Cheryl L. Glenn","raw_affiliation_strings":["Basic Clinical Genomics Laboratory, Department of Physiology and Institute for Biomedical Research, the University of Sydney, Sydney, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Basic Clinical Genomics Laboratory, Department of Physiology and Institute for Biomedical Research, the University of Sydney, Sydney, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071421730","display_name":"Xing Li Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289525096","display_name":"Texas Biomedical Research Institute","ror":"https://ror.org/00wbskb04","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289525096"]},{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]}],"countries":["AU","US"],"is_corresponding":false,"raw_author_name":"Xing Li Wang","raw_affiliation_strings":["Cardiovascular Genetics Laboratory and the","Centre for Thrombosis and Vascular Research, University of New South Wales, Sydney, Australia","Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Genetics Laboratory and the","institution_ids":[]},{"raw_affiliation_string":"Centre for Thrombosis and Vascular Research, University of New South Wales, Sydney, Australia","institution_ids":["https://openalex.org/I31746571"]},{"raw_affiliation_string":"Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas","institution_ids":["https://openalex.org/I1289525096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080414613","display_name":"Stephen Colagiuri","orcid":"https://orcid.org/0000-0002-2398-4781","observed_orcids":["https://orcid.org/0000-0002-2398-4781"]},"institutions":[{"id":"https://openalex.org/I4210108821","display_name":"Prince of Wales Hospital","ror":"https://ror.org/022arq532","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210108821"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Stephen Colagiuri","raw_affiliation_strings":["Department of Endocrinology, Prince of Wales Hospital, Sydney, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology, Prince of Wales Hospital, Sydney, Australia","institution_ids":["https://openalex.org/I4210108821"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022264359","display_name":"Brian J. Morris","orcid":"https://orcid.org/0000-0003-2468-3566","observed_orcids":["https://orcid.org/0000-0003-2468-3566"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Brian J. Morris","raw_affiliation_strings":["Basic Clinical Genomics Laboratory, Department of Physiology and Institute for Biomedical Research, the University of Sydney, Sydney, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Basic Clinical Genomics Laboratory, Department of Physiology and Institute for Biomedical Research, the University of Sydney, Sydney, Australia","institution_ids":["https://openalex.org/I129604602"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0918,"has_fulltext":true,"cited_by_count":25,"citation_normalized_percentile":{"value":0.76188705,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"24","issue":"4","first_page":"753","last_page":"757"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.8339999914169312,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.8339999914169312,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.03660000115633011,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.02710000053048134,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tnf-receptor-2","display_name":"TNF receptor 2","score":0.9980000257492065},{"id":"https://openalex.org/keywords/tumor-necrosis-factor-receptor-2","display_name":"tumor necrosis factor receptor 2","score":0.925000011920929},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.8199999928474426},{"id":"https://openalex.org/keywords/diabetic-neuropathy","display_name":"diabetic neuropathy","score":0.9879999756813049},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.8190000057220459},{"id":"https://openalex.org/keywords/hba1c","display_name":"HbA1c","score":0.9959999918937683},{"id":"https://openalex.org/keywords/microsatellite-polymorphism","display_name":"microsatellite polymorphism","score":0.8759999871253967},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.7480000257492065},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.6579999923706055},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.625},{"id":"https://openalex.org/keywords/essential-hypertension","display_name":"essential hypertension","score":0.7179999947547913},{"id":"https://openalex.org/keywords/hypercholesterolemia","display_name":"hypercholesterolemia","score":0.9800000190734863}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8058357834815979},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7720470428466797},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6452098488807678},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6252350211143494},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.57098788022995},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.5091397166252136},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.4823879301548004},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.45903706550598145},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.4345742464065552},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.42153623700141907},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3611752986907959},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.18105143308639526},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11966386437416077},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0904916524887085}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000419","descriptor_name":"Albuminuria","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001315","descriptor_name":"Australia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D003929","descriptor_name":"Diabetic Neuropathies","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003929","descriptor_name":"Diabetic Neuropathies","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D003929","descriptor_name":"Diabetic Neuropathies","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005819","descriptor_name":"Genetic Markers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006442","descriptor_name":"Glycated Hemoglobin","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008076","descriptor_name":"Cholesterol, HDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008078","descriptor_name":"Cholesterol, LDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014280","descriptor_name":"Triglycerides","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018124","descriptor_name":"Receptors, Tumor Necrosis Factor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D044465","descriptor_name":"White People","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D047889","descriptor_name":"Receptors, Tumor Necrosis Factor, Type II","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.2337/diacare.24.4.753","doi":"https://doi.org/10.2337/diacare.24.4.753","is_oa":true,"landing_page_url":"https://doi.org/10.2337/diacare.24.4.753","pdf_url":"https://diabetesjournals.org/care/article-pdf/24/4/753/588084/753.pdf","source":{"id":"https://openalex.org/S49878492","display_name":"Diabetes Care","issn_l":"0149-5992","issn":["0149-5992","1935-5548"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320274","host_organization_name":"American Diabetes Association","host_organization_lineage":["https://openalex.org/P4310320274"],"host_organization_lineage_names":["American Diabetes Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Care","raw_type":"journal-article"},{"id":"pmid:11315843","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11315843","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes care","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.2337/diacare.24.4.753","doi":"https://doi.org/10.2337/diacare.24.4.753","is_oa":true,"landing_page_url":"https://doi.org/10.2337/diacare.24.4.753","pdf_url":"https://diabetesjournals.org/care/article-pdf/24/4/753/588084/753.pdf","source":{"id":"https://openalex.org/S49878492","display_name":"Diabetes Care","issn_l":"0149-5992","issn":["0149-5992","1935-5548"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320274","host_organization_name":"American Diabetes Association","host_organization_lineage":["https://openalex.org/P4310320274"],"host_organization_lineage_names":["American Diabetes Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Care","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.8500000238418579,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334705","display_name":"National Health and Medical Research Council","ror":"https://ror.org/011kf5r70"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2012389967.pdf","grobid_xml":"https://content.openalex.org/works/W2012389967.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W106370701","https://openalex.org/W350571946","https://openalex.org/W1704134691","https://openalex.org/W1979669454","https://openalex.org/W1992528601","https://openalex.org/W1997494071","https://openalex.org/W2001218312","https://openalex.org/W2008787181","https://openalex.org/W2011386576","https://openalex.org/W2019917186","https://openalex.org/W2022801078","https://openalex.org/W2032810604","https://openalex.org/W2036689136","https://openalex.org/W2056476689","https://openalex.org/W2056707218","https://openalex.org/W2068103783","https://openalex.org/W2071909694","https://openalex.org/W2078617119","https://openalex.org/W2082813709","https://openalex.org/W2086255604","https://openalex.org/W2088105997","https://openalex.org/W2110649443","https://openalex.org/W2113851528","https://openalex.org/W2120897861","https://openalex.org/W2123242787","https://openalex.org/W2124277514","https://openalex.org/W2126067996","https://openalex.org/W2135442422","https://openalex.org/W2162465275","https://openalex.org/W2166252747","https://openalex.org/W2337454357","https://openalex.org/W2397155544","https://openalex.org/W2398701972","https://openalex.org/W2578765318","https://openalex.org/W4233710124","https://openalex.org/W4388361952"],"related_works":["https://openalex.org/W7096119164","https://openalex.org/W1984788009","https://openalex.org/W2091096419","https://openalex.org/W7099440711","https://openalex.org/W2109206920","https://openalex.org/W2037982863","https://openalex.org/W4413832576","https://openalex.org/W2001695786","https://openalex.org/W2572876869","https://openalex.org/W2010762003"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Genetic":[1,203],"variation":[2,204],"in":[3,19,37,41,62,69,91,99,165,205,220],"the":[4,33,38,95,103],"tumor":[5],"necrosis":[6],"factor":[7],"(TNF)":[8],"receptor":[9],"2":[10,21,43,222],"gene":[11],"(TNFRSF1B)":[12],"has":[13],"shown":[14],"association":[15,119],"with":[16,57,85,94,122,132],"insulin":[17],"resistance":[18],"type":[20,42,221],"diabetes,":[22],"hypercholesterolemia,":[23],"coronary":[24],"artery":[25],"disease,":[26],"and":[27,74,143,150,157,163,175,182,216],"essential":[28],"hypertension.":[29],"Here":[30],"we":[31],"tested":[32],"TNFRSF1B":[34,66,208],"marker":[35,56],"used":[36],"latter":[39,226],"studies":[40],"diabetes":[44,126,223],"patients.":[45,224],"RESEARCH":[46],"DESIGN":[47],"AND":[48],"METHODS:":[49],"A":[50],"case-control":[51],"study":[52],"of":[53,65,230],"a":[54,231],"microsatellite":[55],"five":[58],"alleles":[59],"(CA13-":[60],"CA17)":[61],"intron":[63],"4":[64],"was":[67,83,120],"performed":[68],"357":[70],"well-characterized":[71],"white":[72],"patients":[73,93],"183":[75],"healthy":[76],"control":[77],"subjects.":[78],"RESULTS:":[79],"The":[80,128,225],"CA16":[81,129],"allele":[82,130],"associated":[84],"clinical":[86,211],"neuropathy":[87],"(frequency":[88],"=":[89,106,109,113,154,161,186,192],"27%":[90],"69":[92],"condition":[96],"versus":[97],"16%":[98],"230":[100],"subjects":[101],"without":[102],"condition;":[104],"chi2":[105],"9.0,":[107],"P":[108,160,191],"0.011;":[110],"odds":[111],"ratio":[112],"2.1":[114],"[95%":[115],"CI":[116],"1.2-3.8]).":[117],"No":[118],"seen":[121],"other":[123],"complications":[124],"or":[125,206],"itself.":[127],"tracked":[131],"elevation":[133],"plasma":[134,166],"HDL":[135,218],"cholesterol":[136,219],"(1.3":[137],"+/-":[138,141,145,170,173,177],"0.2,":[139,174],"1.2":[140],"0.4,":[142],"1.1":[144],"0.2":[146],"for":[147,179,199],"CA16/CA16,":[148,180],"CA16/-,":[149,181],"-/-,":[151,183],"respectively;":[152,159,184,190],"n":[153,185],"9,":[155,187],"110,":[156],"218,":[158],"0.009)":[162],"reduction":[164],"glycosylated":[167,214],"hemoglobin":[168],"(6.6":[169],"0.3,":[171],"8.3":[172],"8.1":[176],"0.1":[178],"102,":[188],"205,":[189],"0.007)":[193],"Significance":[194],"remained":[195],"after":[196],"Bonferroni":[197],"correction":[198],"multiple":[200],"testing.":[201],"CONCLUSIONS:":[202],"near":[207],"may":[209],"predispose":[210],"neuropathy,":[212],"reduced":[213],"hemoglobin,":[215],"increased":[217],"could":[227],"be":[228],"part":[229],"protective":[232],"response.":[233]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}