{"id":"https://openalex.org/W2012374251","doi":"https://doi.org/10.1902/jop.2005.76.11-s.2168","title":"Resolution of Inflammation in Periodontitis","display_name":"Resolution of Inflammation in Periodontitis","publication_year":2005,"publication_date":"2005-11-01","ids":{"openalex":"https://openalex.org/W2012374251","doi":"https://doi.org/10.1902/jop.2005.76.11-s.2168","mag":"2012374251","pmid":"https://pubmed.ncbi.nlm.nih.gov/16277590","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1350626"},"language":"en","primary_location":{"id":"doi:10.1902/jop.2005.76.11-s.2168","doi":"https://doi.org/10.1902/jop.2005.76.11-s.2168","is_oa":false,"landing_page_url":"https://doi.org/10.1902/jop.2005.76.11-s.2168","pdf_url":null,"source":{"id":"https://openalex.org/S58498366","display_name":"Journal of Periodontology","issn_l":"0022-3492","issn":["0022-3492","1049-8885","1943-3670"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Periodontology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1350626","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018515481","display_name":"Alpdo\u011fan Kantarc\u0131","orcid":"https://orcid.org/0000-0002-2679-9100","observed_orcids":["https://orcid.org/0000-0002-2679-9100"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alpdogan Kantarci","raw_affiliation_strings":["Department of Periodontology and Oral Biology, Boston University Goldman School of Dental Medicine, Boston, MA 02118, USA","Department of Periodontology and Oral Biology, Boston University Goldman School of Dental Medicine, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Periodontology and Oral Biology, Boston University Goldman School of Dental Medicine, Boston, MA 02118, USA","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"Department of Periodontology and Oral Biology, Boston University Goldman School of Dental Medicine, Boston, MA","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014230085","display_name":"Thomas E. Van Dyke","orcid":"https://orcid.org/0000-0003-0568-124X","observed_orcids":["https://orcid.org/0000-0003-0568-124X"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Thomas E. Van Dyke","raw_affiliation_strings":["Department of Periodontology and Oral Biology, Boston University Goldman School of Dental Medicine, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Periodontology and Oral Biology, Boston University Goldman School of Dental Medicine, Boston, MA","institution_ids":["https://openalex.org/I111088046"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5014230085"],"corresponding_institution_ids":["https://openalex.org/I111088046"],"apc_list":{"value":5000,"currency":"USD","value_usd":5000},"apc_paid":null,"fwci":4.6281,"has_fulltext":false,"cited_by_count":66,"citation_normalized_percentile":{"value":0.94523763,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"76","issue":"11S","first_page":"2168","last_page":"2174"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11570","display_name":"Periodontal Regeneration and Treatments","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/periodontitis","display_name":"periodontitis","score":0.9480000138282776},{"id":"https://openalex.org/keywords/resolution-of-inflammation","display_name":"inflammation resolution","score":0.9269999861717224},{"id":"https://openalex.org/keywords/chronic-inflammation","display_name":"chronic inflammation","score":0.8209999799728394},{"id":"https://openalex.org/keywords/inflammatory-mechanisms","display_name":"inflammatory mechanisms","score":0.5350000262260437},{"id":"https://openalex.org/keywords/periodontal-disease","display_name":"periodontal disease","score":0.7609999775886536},{"id":"https://openalex.org/keywords/systemic-inflammation","display_name":"systemic inflammation","score":0.5630000233650208},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.6179999709129333},{"id":"https://openalex.org/keywords/arthritis","display_name":"arthritis","score":0.9679999947547913},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.8289999961853027}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7526829838752747},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.7062586545944214},{"id":"https://openalex.org/C2780385504","wikidata":"https://www.wikidata.org/wiki/Q520127","display_name":"Periodontitis","level":2,"score":0.7019752860069275},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6227974891662598},{"id":"https://openalex.org/C2778380114","wikidata":"https://www.wikidata.org/wiki/Q143652","display_name":"Periodontium","level":2,"score":0.559532880783081},{"id":"https://openalex.org/C2777077863","wikidata":"https://www.wikidata.org/wiki/Q170990","display_name":"Arthritis","level":2,"score":0.5455862283706665},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.39513829350471497},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.35205820202827454},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3305986523628235},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.16721943020820618},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.13794368505477905},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1072203516960144}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005231","descriptor_name":"Fatty Acids, Unsaturated","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D010518","descriptor_name":"Periodontitis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D010518","descriptor_name":"Periodontitis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010518","descriptor_name":"Periodontitis","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D010587","descriptor_name":"Phagocytosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018836","descriptor_name":"Inflammation Mediators","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D044045","descriptor_name":"Lipoxins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1902/jop.2005.76.11-s.2168","doi":"https://doi.org/10.1902/jop.2005.76.11-s.2168","is_oa":false,"landing_page_url":"https://doi.org/10.1902/jop.2005.76.11-s.2168","pdf_url":null,"source":{"id":"https://openalex.org/S58498366","display_name":"Journal of Periodontology","issn_l":"0022-3492","issn":["0022-3492","1049-8885","1943-3670"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Periodontology","raw_type":"journal-article"},{"id":"pmid:16277590","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16277590","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of periodontology","raw_type":"Journal Article"},{"id":"pmid:29539044","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29539044","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of periodontology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1350626","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1350626","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Periodontol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1350626","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1350626","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Periodontol","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4796277574","display_name":"Specialized Center for Oral Inflammation and Resolution","funder_award_id":"P50DE016191","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G5407248525","display_name":"General Clinical Research Center","funder_award_id":"M01RR000533","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"}],"funders":[{"id":"https://openalex.org/F4320337365","display_name":"National Institute of Dental and Craniofacial Research","ror":"https://ror.org/004a2wv92"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W85194748","https://openalex.org/W1497700962","https://openalex.org/W1507009700","https://openalex.org/W1604298518","https://openalex.org/W1836416096","https://openalex.org/W1845306201","https://openalex.org/W1923571095","https://openalex.org/W1970599157","https://openalex.org/W1971236330","https://openalex.org/W1981748455","https://openalex.org/W1985458126","https://openalex.org/W1986796030","https://openalex.org/W1987449056","https://openalex.org/W1987707775","https://openalex.org/W1987989175","https://openalex.org/W1998377876","https://openalex.org/W2013144840","https://openalex.org/W2019954713","https://openalex.org/W2020561358","https://openalex.org/W2024176341","https://openalex.org/W2029251290","https://openalex.org/W2037179116","https://openalex.org/W2039342563","https://openalex.org/W2040801758","https://openalex.org/W2050045837","https://openalex.org/W2056879548","https://openalex.org/W2063252400","https://openalex.org/W2066579296","https://openalex.org/W2073581969","https://openalex.org/W2076443467","https://openalex.org/W2082649626","https://openalex.org/W2083289835","https://openalex.org/W2085757616","https://openalex.org/W2100726346","https://openalex.org/W2103933097","https://openalex.org/W2110628158","https://openalex.org/W2111873809","https://openalex.org/W2119054402","https://openalex.org/W2125543770","https://openalex.org/W2138291177","https://openalex.org/W2147758955","https://openalex.org/W2151840463","https://openalex.org/W2152833639","https://openalex.org/W2153454088","https://openalex.org/W2160381871","https://openalex.org/W2162465757","https://openalex.org/W2163134721","https://openalex.org/W2171105146","https://openalex.org/W2201507391","https://openalex.org/W2256824405","https://openalex.org/W2317823047","https://openalex.org/W2409543526","https://openalex.org/W2409590791","https://openalex.org/W2413937467","https://openalex.org/W2416695338","https://openalex.org/W2472969637"],"related_works":["https://openalex.org/W1512020104","https://openalex.org/W7096003046","https://openalex.org/W7033088723","https://openalex.org/W3125030132","https://openalex.org/W2119338383","https://openalex.org/W22718774","https://openalex.org/W4400511646","https://openalex.org/W2007354773","https://openalex.org/W2417268101","https://openalex.org/W2138357144"],"abstract_inverted_index":{"Chronic":[0],"inflammatory":[1,44,83,90],"illnesses":[2],"such":[3],"as":[4,13,31],"diabetes,":[5],"arthritis,":[6],"and":[7,22,68,88,107],"heart":[8],"disease":[9,66,87],"are":[10,28],"now":[11],"seen":[12],"problems":[14],"that":[15,57],"might":[16],"have":[17],"impacts":[18],"on":[19,51,102],"the":[20,35,43,47,52,65,82,97,104,118],"periodontium,":[21],"reciprocal":[23],"effects":[24,120],"of":[25,37,42,54,64,70,85],"periodontal":[26,86],"diseases":[27],"being":[29],"considered":[30],"factors":[32],"potentially":[33],"affecting":[34],"progression":[36],"these":[38],"diseases.":[39],"Successful":[40],"management":[41],"disorders":[45,94],"in":[46,96],"human":[48],"body":[49],"depends":[50],"identification":[53],"common":[55,89],"pathways":[56],"would":[58],"lead":[59],"to":[60,80,114,122],"a":[61],"better":[62],"understanding":[63],"processes":[67],"development":[69],"novel":[71],"treatment":[72],"strategies.":[73],"In":[74],"this":[75],"review,":[76],"our":[77],"objective":[78],"is":[79],"identify":[81],"basis":[84],"mechanisms":[91],"underlying":[92],"several":[93],"elsewhere":[95],"body,":[98],"with":[99],"an":[100],"emphasis":[101],"how":[103],"potential":[105],"extrinsic":[106],"intrinsic":[108],"control":[109],"methods":[110],"could":[111],"be":[112],"used":[113],"prevent":[115],"or":[116],"treat":[117],"harmful":[119],"linked":[121],"inflammation.":[123]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}