{"id":"https://openalex.org/W2012372286","doi":"https://doi.org/10.1016/j.bbrc.2005.10.164","title":"Human T lymphocytes express N-methyl-d-aspartate receptors functionally active in controlling T cell activation","display_name":"Human T lymphocytes express N-methyl-d-aspartate receptors functionally active in controlling T cell activation","publication_year":2005,"publication_date":"2005-11-10","ids":{"openalex":"https://openalex.org/W2012372286","doi":"https://doi.org/10.1016/j.bbrc.2005.10.164","mag":"2012372286","pmid":"https://pubmed.ncbi.nlm.nih.gov/16289038"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbrc.2005.10.164","doi":"https://doi.org/10.1016/j.bbrc.2005.10.164","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bbrc.2005.10.164","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058390513","display_name":"Gianluca Miglio","orcid":"https://orcid.org/0000-0002-6602-2099","observed_orcids":["https://orcid.org/0000-0002-6602-2099"]},"institutions":[{"id":"https://openalex.org/I123338534","display_name":"Universit\u00e0 degli Studi del Piemonte Orientale \u201cAmedeo Avogadro\u201d","ror":"https://ror.org/04387x656","country_code":"IT","type":"education","lineage":["https://openalex.org/I123338534"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gianluca Miglio","raw_affiliation_strings":["DiSCAFF Department, Eastern Piedmont University, Via Bovio 6, 28100 Novara, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DiSCAFF Department, Eastern Piedmont University, Via Bovio 6, 28100 Novara, Italy","institution_ids":["https://openalex.org/I123338534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028469690","display_name":"Federica Varsaldi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I123338534","display_name":"Universit\u00e0 degli Studi del Piemonte Orientale \u201cAmedeo Avogadro\u201d","ror":"https://ror.org/04387x656","country_code":"IT","type":"education","lineage":["https://openalex.org/I123338534"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Federica Varsaldi","raw_affiliation_strings":["DiSCAFF Department, Eastern Piedmont University, Via Bovio 6, 28100 Novara, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DiSCAFF Department, Eastern Piedmont University, Via Bovio 6, 28100 Novara, Italy","institution_ids":["https://openalex.org/I123338534"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103763038","display_name":"Grazia Lombardi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I123338534","display_name":"Universit\u00e0 degli Studi del Piemonte Orientale \u201cAmedeo Avogadro\u201d","ror":"https://ror.org/04387x656","country_code":"IT","type":"education","lineage":["https://openalex.org/I123338534"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Grazia Lombardi","raw_affiliation_strings":["DiSCAFF Department, Eastern Piedmont University, Via Bovio 6, 28100 Novara, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DiSCAFF Department, Eastern Piedmont University, Via Bovio 6, 28100 Novara, Italy","institution_ids":["https://openalex.org/I123338534"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5103763038"],"corresponding_institution_ids":["https://openalex.org/I123338534"],"apc_list":{"value":3110,"currency":"USD","value_usd":3110},"apc_paid":null,"fwci":1.2429,"has_fulltext":false,"cited_by_count":110,"citation_normalized_percentile":{"value":0.7481502,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"338","issue":"4","first_page":"1875","last_page":"1883"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.8403000235557556,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.8403000235557556,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.04190000146627426,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12770","display_name":"Amino Acid Enzymes and Metabolism","score":0.03720000013709068,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nmda-receptor","display_name":"NMDA receptor","score":0.9670000076293945},{"id":"https://openalex.org/keywords/t-cells","display_name":"T cells","score":0.8700000047683716},{"id":"https://openalex.org/keywords/t-cell-activation","display_name":"T cell activation","score":0.9850000143051147},{"id":"https://openalex.org/keywords/nr1-subunit","display_name":"NR1 subunit","score":0.9269999861717224},{"id":"https://openalex.org/keywords/nr2b-subunit","display_name":"NR2B subunit","score":0.9070000052452087},{"id":"https://openalex.org/keywords/d-ap5","display_name":"D-AP5","score":0.7540000081062317},{"id":"https://openalex.org/keywords/mk-801","display_name":"MK-801","score":0.9129999876022339},{"id":"https://openalex.org/keywords/phytohemagglutinin","display_name":"phytohemagglutinin","score":0.8830000162124634},{"id":"https://openalex.org/keywords/interleukin-2","display_name":"interleukin-2","score":0.8759999871253967},{"id":"https://openalex.org/keywords/cd25-expression","display_name":"CD25 expression","score":0.8529999852180481},{"id":"https://openalex.org/keywords/cell-aggregation","display_name":"cell aggregation","score":0.6510000228881836},{"id":"https://openalex.org/keywords/t-cell-proliferation","display_name":"T cell proliferation","score":0.6449999809265137},{"id":"https://openalex.org/keywords/ionotropic-glutamate-receptors","display_name":"ionotropic glutamate receptors","score":0.6340000033378601}],"concepts":[{"id":"https://openalex.org/C67018056","wikidata":"https://www.wikidata.org/wiki/Q414896","display_name":"NMDA receptor","level":3,"score":0.7587333917617798},{"id":"https://openalex.org/C179464577","wikidata":"https://www.wikidata.org/wiki/Q1632589","display_name":"Jurkat cells","level":4,"score":0.7375112771987915},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.6733076572418213},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.5947831869125366},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5657252073287964},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5400856733322144},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.48968270421028137},{"id":"https://openalex.org/C79484868","wikidata":"https://www.wikidata.org/wiki/Q5971673","display_name":"IL-2 receptor","level":4,"score":0.4876164495944977},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.44963571429252625},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3125802278518677},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.18227988481521606},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.14763689041137695}],"mesh":[{"descriptor_ui":"D002453","descriptor_name":"Cell Cycle","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007376","descriptor_name":"Interleukin-2","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007963","descriptor_name":"Leukocytes, Mononuclear","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008213","descriptor_name":"Lymphocyte Activation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015375","descriptor_name":"Receptors, Interleukin-2","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D015375","descriptor_name":"Receptors, Interleukin-2","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D015763","descriptor_name":"2-Amino-5-phosphonovalerate","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D016194","descriptor_name":"Receptors, N-Methyl-D-Aspartate","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D016194","descriptor_name":"Receptors, N-Methyl-D-Aspartate","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D016194","descriptor_name":"Receptors, N-Methyl-D-Aspartate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016291","descriptor_name":"Dizocilpine Maleate","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.bbrc.2005.10.164","doi":"https://doi.org/10.1016/j.bbrc.2005.10.164","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bbrc.2005.10.164","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},{"id":"pmid:16289038","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16289038","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and biophysical research communications","raw_type":"Journal Article"},{"id":"pmh:oai:iris.unito.it:2318/7062","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2318/7062","pdf_url":null,"source":{"id":"https://openalex.org/S4306400637","display_name":"Institutional Research Information System University of Turin (University of Turin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I55143463","host_organization_name":"University of Turin","host_organization_lineage":["https://openalex.org/I55143463"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W43991711","https://openalex.org/W1523162832","https://openalex.org/W1554736362","https://openalex.org/W1561736917","https://openalex.org/W1579591510","https://openalex.org/W1600539804","https://openalex.org/W1942202520","https://openalex.org/W1979523453","https://openalex.org/W1980856393","https://openalex.org/W1984252028","https://openalex.org/W1995032030","https://openalex.org/W1999934349","https://openalex.org/W2011619507","https://openalex.org/W2011654786","https://openalex.org/W2013374077","https://openalex.org/W2017610520","https://openalex.org/W2018199192","https://openalex.org/W2020939800","https://openalex.org/W2025105921","https://openalex.org/W2032435880","https://openalex.org/W2035798975","https://openalex.org/W2041024256","https://openalex.org/W2058870251","https://openalex.org/W2065169750","https://openalex.org/W2065848862","https://openalex.org/W2068189481","https://openalex.org/W2071685414","https://openalex.org/W2074900847","https://openalex.org/W2091765514","https://openalex.org/W2106042714","https://openalex.org/W2109495864","https://openalex.org/W2114918609","https://openalex.org/W2121239869","https://openalex.org/W2121569266","https://openalex.org/W2122532139","https://openalex.org/W2132446815","https://openalex.org/W2134966618","https://openalex.org/W2140899588","https://openalex.org/W2147294326","https://openalex.org/W2159014320","https://openalex.org/W2468119228","https://openalex.org/W4251348922","https://openalex.org/W4253885482","https://openalex.org/W4322388488","https://openalex.org/W4406059073"],"related_works":["https://openalex.org/W2003139984","https://openalex.org/W2102515794","https://openalex.org/W2089519174","https://openalex.org/W2759941852","https://openalex.org/W7120776019","https://openalex.org/W2076282449","https://openalex.org/W2069678140","https://openalex.org/W2121208257","https://openalex.org/W2809045785","https://openalex.org/W6964841682"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":10}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}