{"id":"https://openalex.org/W2012260534","doi":"https://doi.org/10.13031/2013.32718","title":"Detection of Escherichia coli O157:H7 Using Interdigitated Array Microelectrode-Based Immunosensor","display_name":"Detection of Escherichia coli O157:H7 Using Interdigitated Array Microelectrode-Based Immunosensor","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W2012260534","doi":"https://doi.org/10.13031/2013.32718","mag":"2012260534"},"language":"en","primary_location":{"id":"doi:10.13031/2013.32718","doi":"https://doi.org/10.13031/2013.32718","is_oa":false,"landing_page_url":"https://doi.org/10.13031/2013.32718","pdf_url":null,"source":{"id":"https://openalex.org/S4210212270","display_name":"Biological Engineering","issn_l":"1934-2799","issn":["1934-2799","1934-2837"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological Engineering","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100642712","display_name":"Yun Wang","orcid":"https://orcid.org/0000-0002-7711-1126","observed_orcids":["https://orcid.org/0000-0002-7711-1126"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y. Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"R. Wang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100771498","display_name":"Yanbin Li","orcid":"https://orcid.org/0000-0002-4142-7743","observed_orcids":["https://orcid.org/0000-0002-4142-7743"]},"institutions":[{"id":"https://openalex.org/I78715868","display_name":"University of Arkansas at Fayetteville","ror":"https://ror.org/05jbt9m15","country_code":"US","type":"education","lineage":["https://openalex.org/I78715868"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Y. Li","raw_affiliation_strings":["University Of Arkansas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Of Arkansas","institution_ids":["https://openalex.org/I78715868"]}]},{"author_position":"middle","author":{"id":null,"display_name":"B. Srinivasan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B. Srinivasan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068135140","display_name":"Steve C. H. Tung","orcid":"https://orcid.org/0000-0003-3713-4494","observed_orcids":["https://orcid.org/0000-0003-3713-4494"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. Tung","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"H. Wang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H. Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111770280","display_name":"M. F. Slavik","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. F. Slavik","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5090223888","display_name":"Carl L. Griffis","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C. L. Griffis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.7565,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.75564847,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"2","issue":"2","first_page":"49","last_page":"62"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.7411999702453613,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.7411999702453613,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.08550000190734863,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.04170000180602074,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/escherichia-coli-o157-h7","display_name":"Escherichia coli O157:H7","score":0.9980000257492065},{"id":"https://openalex.org/keywords/label-free-immunosensor","display_name":"label-free immunosensor","score":0.8949999809265137},{"id":"https://openalex.org/keywords/impedance-spectroscopy","display_name":"impedance spectroscopy","score":0.7170000076293945},{"id":"https://openalex.org/keywords/protein-a","display_name":"protein A","score":0.878000020980835},{"id":"https://openalex.org/keywords/foodborne-pathogen-detection","display_name":"foodborne pathogen detection","score":0.8539999723434448},{"id":"https://openalex.org/keywords/food-safety","display_name":"food safety","score":0.8629999756813049},{"id":"https://openalex.org/keywords/chicken-carcasses","display_name":"chicken carcasses","score":0.8420000076293945},{"id":"https://openalex.org/keywords/ground-beef","display_name":"ground beef","score":0.996999979019165}],"concepts":[{"id":"https://openalex.org/C111670793","wikidata":"https://www.wikidata.org/wiki/Q16979465","display_name":"Microelectrode","level":3,"score":0.9100083708763123},{"id":"https://openalex.org/C95967509","wikidata":"https://www.wikidata.org/wiki/Q1952355","display_name":"Multielectrode array","level":4,"score":0.5822880864143372},{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.5621981024742126},{"id":"https://openalex.org/C113196181","wikidata":"https://www.wikidata.org/wiki/Q485223","display_name":"Analytical Chemistry (journal)","level":2,"score":0.5189775824546814},{"id":"https://openalex.org/C956191","wikidata":"https://www.wikidata.org/wiki/Q930144","display_name":"Polyclonal antibodies","level":3,"score":0.5032903552055359},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5021958351135254},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.5003995895385742},{"id":"https://openalex.org/C17829176","wikidata":"https://www.wikidata.org/wiki/Q179043","display_name":"Electrical impedance","level":2,"score":0.4952322542667389},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.4894486963748932},{"id":"https://openalex.org/C96616956","wikidata":"https://www.wikidata.org/wiki/Q285100","display_name":"Phosphate buffered saline","level":2,"score":0.4566251039505005},{"id":"https://openalex.org/C119128265","wikidata":"https://www.wikidata.org/wiki/Q900165","display_name":"Detection limit","level":2,"score":0.43023407459259033},{"id":"https://openalex.org/C7040849","wikidata":"https://www.wikidata.org/wiki/Q899580","display_name":"Dielectric spectroscopy","level":4,"score":0.4122184216976166},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4117732048034668},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.267204225063324},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.22780266404151917},{"id":"https://openalex.org/C52859227","wikidata":"https://www.wikidata.org/wiki/Q7877","display_name":"Electrochemistry","level":3,"score":0.1459718644618988},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.114848792552948},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09042230248451233},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08718296885490417},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.13031/2013.32718","doi":"https://doi.org/10.13031/2013.32718","is_oa":false,"landing_page_url":"https://doi.org/10.13031/2013.32718","pdf_url":null,"source":{"id":"https://openalex.org/S4210212270","display_name":"Biological Engineering","issn_l":"1934-2799","issn":["1934-2799","1934-2837"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological Engineering","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W195809865","https://openalex.org/W1954377869","https://openalex.org/W1977154301","https://openalex.org/W1992262689","https://openalex.org/W1993510035","https://openalex.org/W2001587260","https://openalex.org/W2001786288","https://openalex.org/W2009599826","https://openalex.org/W2020990353","https://openalex.org/W2021194242","https://openalex.org/W2035070293","https://openalex.org/W2037775950","https://openalex.org/W2037865481","https://openalex.org/W2044665723","https://openalex.org/W2050224820","https://openalex.org/W2057057273","https://openalex.org/W2059570909","https://openalex.org/W2060605943","https://openalex.org/W2083896641","https://openalex.org/W2140311155","https://openalex.org/W2149411493","https://openalex.org/W2435055054"],"related_works":["https://openalex.org/W2036625700","https://openalex.org/W1967562255","https://openalex.org/W1993510035","https://openalex.org/W1998614521","https://openalex.org/W2365848611","https://openalex.org/W7110668643","https://openalex.org/W2076680456","https://openalex.org/W2216312176","https://openalex.org/W2014415162","https://openalex.org/W1991009926"],"abstract_inverted_index":{"In":[0],"this":[1],"study,":[2],"a":[3,106,132,149,168],"label-free":[4],"interdigitated":[5],"array":[6],"(IDA)":[7],"microelectrode-based":[8],"immunosensor":[9,225,243],"was":[10,43,76,110,129,194,205,226,247,281],"designed":[11],"and":[12,16,37,41,48,85,126,188,232,257],"tested":[13],"for":[14,87,244],"rapid":[15],"sensitive":[17],"detection":[18],"of":[19,25,31,81,118,152,163,185,192,199,214,223,234,241,272],"E.":[20,55,63,164,215,263,273],"coli":[21,56,64,165,216,264,274],"O157:H7.":[22,57,265],"The":[23,142,221,239],"surface":[24,80,280],"gold":[26],"IDA":[27],"microelectrodes":[28,84],"(25":[29],"pairs":[30],"fingers":[32],"with":[33,45,51,108,159,249,262],"700":[34],"m":[35,39],"length":[36],"10":[38],"width":[40],"space)":[42],"modified":[44,83],"protein":[46],"A":[47,58,179],"further":[49],"immobilized":[50,102],"polyclonal":[52],"antibodies":[53,101],"against":[54],"20":[59,177],"L":[60],"sample":[61],"containing":[62],"O157:H7":[65,166,217,275],"in":[66,148,167],"0.01":[67],"M":[68],"phosphate":[69],"buffered":[70],"saline":[71],"(PBS)":[72],"at":[73,90,196],"pH":[74],"7.4":[75],"dropped":[77],"on":[78,103,277],"the":[79,82,94,100,104,119,122,146,160,183,189,197,224,242,267,270,278],"incubated":[86],"2":[88,173,219],"h":[89],"room":[91],"temperature.":[92],"After":[93],"target":[95],"bacteria":[96],"were":[97],"captured":[98],"by":[99],"microelectrode,":[105],"wash":[107],"PBS":[109],"applied":[111],"to":[112,139,155,172,207],"rinse":[113],"off":[114],"all":[115],"unbound":[116],"parts":[117],"sample.":[120],"Finally,":[121],"impedance,":[123],"both":[124],"magnitude":[125,184],"phase":[127],"angle,":[128],"measured":[130,186],"over":[131],"broad":[133],"frequency":[134,150,198],"range":[135,151,169],"from":[136,170],"1":[137,140,153,156,200],"Hz":[138,154],"MHz.":[141],"results":[143],"showed":[144],"that":[145],"impedance":[147,187],"kHz":[157],"increased":[158],"increasing":[161],"number":[162,191],"80":[171,212],"105":[174],"cells":[175,193,213,276],"per":[176],"L.":[178],"linear":[180],"relationship":[181],"between":[182],"log":[190],"determined":[195],"kHz.":[201],"This":[202],"biosensing":[203],"method":[204],"able":[206],"detect":[208],"as":[209,211],"few":[210],"within":[218],"h.":[220],"specificity":[222],"validated":[227],"using":[228,283],"five":[229],"non-target":[230],"bacteria,":[231],"none":[233],"them":[235],"generated":[236],"detectable":[237],"signals.":[238],"application":[240],"food":[245,250],"safety":[246],"demonstrated":[248],"samples":[251],"including":[252],"chicken":[253],"carcasses,":[254],"ground":[255],"beef,":[256],"fresh":[258],"cut":[259],"broccoli":[260],"inoculated":[261],"At":[266],"same":[268],"time,":[269],"capture":[271],"microelectrode":[279],"confirmed":[282],"atomic":[284],"force":[285],"microscopy.":[286]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-01T08:54:57.152042","created_date":"2016-06-24T00:00:00"}