{"id":"https://openalex.org/W2012209476","doi":"https://doi.org/10.1073/pnas.94.8.3943","title":"Transgenic expression of CD95 ligand on islet \u03b2 cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts","display_name":"Transgenic expression of CD95 ligand on islet \u03b2 cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts","publication_year":1997,"publication_date":"1997-04-15","ids":{"openalex":"https://openalex.org/W2012209476","doi":"https://doi.org/10.1073/pnas.94.8.3943","mag":"2012209476","pmid":"https://pubmed.ncbi.nlm.nih.gov/9108084","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/20547"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.94.8.3943","doi":"https://doi.org/10.1073/pnas.94.8.3943","is_oa":true,"landing_page_url":"https://doi.org/10.1073/pnas.94.8.3943","pdf_url":"https://www.pnas.org/doi/pdf/10.1073/pnas.94.8.3943","source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2012209476"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.pnas.org/doi/pdf/10.1073/pnas.94.8.3943","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103579241","display_name":"Janette Allison","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1320473756","display_name":"The Royal Melbourne Hospital","ror":"https://ror.org/005bvs909","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1320473756","https://openalex.org/I4210158168"]},{"id":"https://openalex.org/I196021976","display_name":"Walter and Eliza Hall Institute of Medical Research","ror":"https://ror.org/01b6kha49","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I196021976"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Janette Allison","raw_affiliation_strings":["The Walter and Eliza Hall Institute for Medical Research, Post Office Royal Melbourne Hospital, Victoria 3050, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Walter and Eliza Hall Institute for Medical Research, Post Office Royal Melbourne Hospital, Victoria 3050, Australia","institution_ids":["https://openalex.org/I1320473756","https://openalex.org/I196021976"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001745106","display_name":"Harry Michael Georgiou","orcid":"https://orcid.org/0000-0003-0553-9489","observed_orcids":["https://orcid.org/0000-0003-0553-9489"]},"institutions":[{"id":"https://openalex.org/I1320473756","display_name":"The Royal Melbourne Hospital","ror":"https://ror.org/005bvs909","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1320473756","https://openalex.org/I4210158168"]},{"id":"https://openalex.org/I196021976","display_name":"Walter and Eliza Hall Institute of Medical Research","ror":"https://ror.org/01b6kha49","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I196021976"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Harry M. Georgiou","raw_affiliation_strings":["The Walter and Eliza Hall Institute for Medical Research, Post Office Royal Melbourne Hospital, Victoria 3050, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Walter and Eliza Hall Institute for Medical Research, Post Office Royal Melbourne Hospital, Victoria 3050, Australia","institution_ids":["https://openalex.org/I1320473756","https://openalex.org/I196021976"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046532595","display_name":"Andreas Strasser","orcid":"https://orcid.org/0000-0002-5020-4891","observed_orcids":["https://orcid.org/0000-0002-5020-4891"]},"institutions":[{"id":"https://openalex.org/I1320473756","display_name":"The Royal Melbourne Hospital","ror":"https://ror.org/005bvs909","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1320473756","https://openalex.org/I4210158168"]},{"id":"https://openalex.org/I196021976","display_name":"Walter and Eliza Hall Institute of Medical Research","ror":"https://ror.org/01b6kha49","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I196021976"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Andreas Strasser","raw_affiliation_strings":["The Walter and Eliza Hall Institute for Medical Research, Post Office Royal Melbourne Hospital, Victoria 3050, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Walter and Eliza Hall Institute for Medical Research, Post Office Royal Melbourne Hospital, Victoria 3050, Australia","institution_ids":["https://openalex.org/I1320473756","https://openalex.org/I196021976"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084068397","display_name":"David Lawrence Vaux","orcid":"https://orcid.org/0000-0003-2703-1651","observed_orcids":["https://orcid.org/0000-0003-2703-1651"]},"institutions":[{"id":"https://openalex.org/I1320473756","display_name":"The Royal Melbourne Hospital","ror":"https://ror.org/005bvs909","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1320473756","https://openalex.org/I4210158168"]},{"id":"https://openalex.org/I196021976","display_name":"Walter and Eliza Hall Institute of Medical Research","ror":"https://ror.org/01b6kha49","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I196021976"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"David L. Vaux","raw_affiliation_strings":["The Walter and Eliza Hall Institute for Medical Research, Post Office Royal Melbourne Hospital, Victoria 3050, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Walter and Eliza Hall Institute for Medical Research, Post Office Royal Melbourne Hospital, Victoria 3050, Australia","institution_ids":["https://openalex.org/I1320473756","https://openalex.org/I196021976"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5103579241"],"corresponding_institution_ids":["https://openalex.org/I1320473756","https://openalex.org/I196021976"],"apc_list":null,"apc_paid":null,"fwci":26.6141,"has_fulltext":false,"cited_by_count":366,"citation_normalized_percentile":{"value":0.99863461,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"94","issue":"8","first_page":"3943","last_page":"3947"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.9032999873161316,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.9032999873161316,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.04010000079870224,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.028300000354647636,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fas-ligand","display_name":"Fas ligand","score":0.9869999885559082},{"id":"https://openalex.org/keywords/pancreatic-beta-cells","display_name":"pancreatic beta cells","score":0.7239999771118164},{"id":"https://openalex.org/keywords/immune-privilege","display_name":"immune privilege","score":0.8569999933242798},{"id":"https://openalex.org/keywords/islet-allograft-rejection","display_name":"islet allograft rejection","score":0.8460000157356262},{"id":"https://openalex.org/keywords/granulocytic-infiltration","display_name":"granulocytic infiltration","score":0.8980000019073486},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.5730000138282776},{"id":"https://openalex.org/keywords/transgenic-mice","display_name":"transgenic mice","score":0.7419999837875366},{"id":"https://openalex.org/keywords/fetal-pancreas-transplantation","display_name":"fetal pancreas transplantation","score":0.7400000095367432},{"id":"https://openalex.org/keywords/allograft-rejection","display_name":"allograft rejection","score":0.44200000166893005}],"concepts":[{"id":"https://openalex.org/C2781185574","wikidata":"https://www.wikidata.org/wiki/Q3404271","display_name":"Immune privilege","level":3,"score":0.8189939260482788},{"id":"https://openalex.org/C165220095","wikidata":"https://www.wikidata.org/wiki/Q207524","display_name":"Islet","level":3,"score":0.758590817451477},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.599635124206543},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5659955739974976},{"id":"https://openalex.org/C3031857","wikidata":"https://www.wikidata.org/wiki/Q1649375","display_name":"Fas receptor","level":4,"score":0.5396175384521484},{"id":"https://openalex.org/C153400128","wikidata":"https://www.wikidata.org/wiki/Q3150731","display_name":"Infiltration (HVAC)","level":2,"score":0.5384130477905273},{"id":"https://openalex.org/C102230213","wikidata":"https://www.wikidata.org/wiki/Q430117","display_name":"Transgene","level":3,"score":0.5333405137062073},{"id":"https://openalex.org/C141035611","wikidata":"https://www.wikidata.org/wiki/Q5532934","display_name":"Genetically modified mouse","level":4,"score":0.5313658714294434},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.5221648216247559},{"id":"https://openalex.org/C2779855799","wikidata":"https://www.wikidata.org/wiki/Q728309","display_name":"Pancreatic islets","level":4,"score":0.48087766766548157},{"id":"https://openalex.org/C66008609","wikidata":"https://www.wikidata.org/wiki/Q14866113","display_name":"Fas ligand","level":4,"score":0.4240989089012146},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.4194728434085846},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.41401243209838867},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3851257562637329},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3564934730529785},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.269362211227417},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24957546591758728},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21141460537910461},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.19734078645706177},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.1364349126815796},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11521714925765991},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006085","descriptor_name":"Graft Survival","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006098","descriptor_name":"Granulocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006098","descriptor_name":"Granulocytes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008822","descriptor_name":"Mice, Transgenic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014184","descriptor_name":"Transplantation, Homologous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016381","descriptor_name":"Islets of Langerhans Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018014","descriptor_name":"Gene Transfer Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053222","descriptor_name":"Fas Ligand Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1073/pnas.94.8.3943","doi":"https://doi.org/10.1073/pnas.94.8.3943","is_oa":true,"landing_page_url":"https://doi.org/10.1073/pnas.94.8.3943","pdf_url":"https://www.pnas.org/doi/pdf/10.1073/pnas.94.8.3943","source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:189633","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC20547","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:9108084","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9108084","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:20547","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC20547/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1073/pnas.94.8.3943","doi":"https://doi.org/10.1073/pnas.94.8.3943","is_oa":true,"landing_page_url":"https://doi.org/10.1073/pnas.94.8.3943","pdf_url":"https://www.pnas.org/doi/pdf/10.1073/pnas.94.8.3943","source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2012209476.pdf"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W335065683","https://openalex.org/W1518896693","https://openalex.org/W1831418501","https://openalex.org/W1975216258","https://openalex.org/W1976692354","https://openalex.org/W1978018492","https://openalex.org/W1992060545","https://openalex.org/W1995015674","https://openalex.org/W2004645606","https://openalex.org/W2008882737","https://openalex.org/W2014237867","https://openalex.org/W2041466047","https://openalex.org/W2065413461","https://openalex.org/W2065987343","https://openalex.org/W2076229621","https://openalex.org/W2076530564","https://openalex.org/W2078901980","https://openalex.org/W2089723533","https://openalex.org/W2097106158","https://openalex.org/W2399742535","https://openalex.org/W2403463743"],"related_works":["https://openalex.org/W2058477460","https://openalex.org/W2355668985","https://openalex.org/W2080018906","https://openalex.org/W2353247467","https://openalex.org/W2351081611","https://openalex.org/W2034295054","https://openalex.org/W2802834987","https://openalex.org/W2094982703","https://openalex.org/W2054713720","https://openalex.org/W1891714256"],"abstract_inverted_index":{"Binding":[0],"of":[1,12,31,84,88,113,119],"CD95":[2],"(Fas/APO-1)":[3],"by":[4,17],"its":[5],"ligand":[6],"(CD95L)":[7],"commonly":[8],"induces":[9],"apoptosis.":[10],"Apoptosis":[11],"activated":[13],"T":[14],"cells,":[15],"induced":[16],"CD95L":[18,56,70,89,114,120],"expressed":[19],"in":[20,104],"the":[21,29,81,93],"rodent":[22],"testis,":[23],"has":[24],"been":[25],"proposed":[26],"to":[27,91,125],"be":[28,123],"mechanism":[30],"immune":[32],"privilege":[33],"[Bellgrau,":[34],"D.,":[35,37],"Gold,":[36],"Selawry,":[38],"H.,":[39],"Moore,":[40],"J.,":[41],"Franzusoff,":[42],"A.":[43],"&":[44],"Duke,":[45],"R.":[46],"C.":[47],"(1995)":[48],"Nature":[49],"(London)":[50],"377,":[51],"630-632].":[52],"To":[53],"test":[54],"whether":[55],"could":[57],"protect":[58,92,126],"pancreatic":[59],"islet":[60,73],"grafts":[61,94],"from":[62,95],"rejection,":[63],"we":[64],"made":[65],"transgenic":[66,98],"mice":[67,99],"expressing":[68],"murine":[69],"on":[71],"their":[72,105],"beta":[74],"cells":[75],"and":[76,115],"transplanted":[77],"fetal":[78],"pancreata":[79],"under":[80],"kidney":[82],"capsules":[83],"allogeneic":[85],"animals.":[86],"Expression":[87],"failed":[90],"rejection.":[96],"However,":[97],"developed":[100],"a":[101,110],"granulocytic":[102],"infiltration":[103],"pancreata.":[106],"These":[107],"results":[108],"demonstrate":[109],"pro-inflammatory":[111],"function":[112],"suggest":[116],"that":[117],"expression":[118],"may":[121],"not":[122],"sufficient":[124],"organ":[127],"allografts.":[128]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}