{"id":"https://openalex.org/W2012194493","doi":"https://doi.org/10.2165/00003495-200060050-00009","title":"Lercanidipine","display_name":"Lercanidipine","publication_year":2000,"publication_date":"2000-11-01","ids":{"openalex":"https://openalex.org/W2012194493","doi":"https://doi.org/10.2165/00003495-200060050-00009","mag":"2012194493","pmid":"https://pubmed.ncbi.nlm.nih.gov/11129125"},"language":"eo","primary_location":{"id":"doi:10.2165/00003495-200060050-00009","doi":"https://doi.org/10.2165/00003495-200060050-00009","is_oa":false,"landing_page_url":"https://doi.org/10.2165/00003495-200060050-00009","pdf_url":null,"source":{"id":"https://openalex.org/S4436492","display_name":"Drugs","issn_l":"0012-6667","issn":["0012-6667","1179-1950"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320330","host_organization_name":"Adis, Springer Healthcare","host_organization_lineage":["https://openalex.org/P4310320330","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Adis, Springer Healthcare","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drugs","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111753581","display_name":"Karen J. McClellan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Karen J. McClellan","raw_affiliation_strings":["Adis International Limited, Auckland, New Zealand. demail@adis.co.nz","Adis International limited, Auckland, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adis International Limited, Auckland, New Zealand. demail@adis.co.nz","institution_ids":[]},{"raw_affiliation_string":"Adis International limited, Auckland, New Zealand","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070402673","display_name":"Blair Jarvis","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Blair Jarvis","raw_affiliation_strings":["Adis International Limited, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, Auckland 10, New Zealand","Adis International Limited, Mairangi Bay, Auckland 10, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adis International Limited, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, Auckland 10, New Zealand","institution_ids":[]},{"raw_affiliation_string":"Adis International Limited, Mairangi Bay, Auckland 10, New Zealand","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5111753581"],"corresponding_institution_ids":[],"apc_list":{"value":5990,"currency":"USD","value_usd":5990},"apc_paid":null,"fwci":5.0818,"has_fulltext":false,"cited_by_count":119,"citation_normalized_percentile":{"value":0.95484038,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"60","issue":"5","first_page":"1123","last_page":"1140"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lercanidipine","display_name":"lercanidipine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/calcium-channel-blockers","display_name":"calcium channel blockers","score":0.7799999713897705},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.5370000004768372},{"id":"https://openalex.org/keywords/blood-pressure-reduction","display_name":"blood pressure reduction","score":0.796999990940094},{"id":"https://openalex.org/keywords/isolated-systolic-hypertension","display_name":"isolated systolic hypertension","score":0.8180000185966492},{"id":"https://openalex.org/keywords/elderly-patients","display_name":"elderly patients","score":0.6940000057220459},{"id":"https://openalex.org/keywords/severe-hypertension","display_name":"severe hypertension","score":0.6769999861717224},{"id":"https://openalex.org/keywords/adjunctive-therapy","display_name":"adjunctive therapy","score":0.722000002861023},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.8550000190734863},{"id":"https://openalex.org/keywords/antihypertensive-efficacy","display_name":"antihypertensive efficacy","score":0.6190000176429749},{"id":"https://openalex.org/keywords/anti-atherogenic-effects","display_name":"antiatherogenic effects","score":0.6899999976158142},{"id":"https://openalex.org/keywords/l-type-calcium-channels","display_name":"L-type calcium channels","score":0.6309999823570251},{"id":"https://openalex.org/keywords/adverse-effects","display_name":"adverse effects","score":0.5059999823570251},{"id":"https://openalex.org/keywords/drug-interactions","display_name":"drug interactions","score":0.6029999852180481},{"id":"https://openalex.org/keywords/contraindications","display_name":"contraindications","score":0.6460000276565552}],"concepts":[{"id":"https://openalex.org/C2779283177","wikidata":"https://www.wikidata.org/wiki/Q410492","display_name":"Lercanidipine","level":3,"score":0.9934929609298706},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7537193298339844},{"id":"https://openalex.org/C2780361556","wikidata":"https://www.wikidata.org/wiki/Q423930","display_name":"Hydrochlorothiazide","level":3,"score":0.665245771408081},{"id":"https://openalex.org/C2775940317","wikidata":"https://www.wikidata.org/wiki/Q422185","display_name":"Enalapril","level":4,"score":0.6517099142074585},{"id":"https://openalex.org/C2779646130","wikidata":"https://www.wikidata.org/wiki/Q411347","display_name":"Amlodipine","level":3,"score":0.6250753998756409},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5526752471923828},{"id":"https://openalex.org/C2779066535","wikidata":"https://www.wikidata.org/wiki/Q39111","display_name":"Nifedipine","level":3,"score":0.5247595310211182},{"id":"https://openalex.org/C2776992270","wikidata":"https://www.wikidata.org/wiki/Q596022","display_name":"Quinapril","level":5,"score":0.48971012234687805},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.4871616065502167},{"id":"https://openalex.org/C2779572014","wikidata":"https://www.wikidata.org/wiki/Q1163827","display_name":"Lacidipine","level":4,"score":0.4650591015815735},{"id":"https://openalex.org/C2780648877","wikidata":"https://www.wikidata.org/wiki/Q420644","display_name":"Felodipine","level":3,"score":0.4445263743400574},{"id":"https://openalex.org/C2781212610","wikidata":"https://www.wikidata.org/wiki/Q39094","display_name":"Dihydropyridine","level":3,"score":0.4444705843925476},{"id":"https://openalex.org/C2777097880","wikidata":"https://www.wikidata.org/wiki/Q988405","display_name":"Essential hypertension","level":3,"score":0.42430856823921204},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.38712453842163086},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36388635635375977},{"id":"https://openalex.org/C2779611605","wikidata":"https://www.wikidata.org/wiki/Q288280","display_name":"ACE inhibitor","level":4,"score":0.27697044610977173},{"id":"https://openalex.org/C2776885963","wikidata":"https://www.wikidata.org/wiki/Q245204","display_name":"Antagonist","level":3,"score":0.25876182317733765},{"id":"https://openalex.org/C27016395","wikidata":"https://www.wikidata.org/wiki/Q128861","display_name":"Angiotensin-converting enzyme","level":3,"score":0.18738043308258057},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000959","descriptor_name":"Antihypertensive Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000959","descriptor_name":"Antihypertensive Agents","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D000959","descriptor_name":"Antihypertensive Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004095","descriptor_name":"Dihydropyridines","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D004095","descriptor_name":"Dihydropyridines","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D004095","descriptor_name":"Dihydropyridines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004334","descriptor_name":"Drug Administration Schedule","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004347","descriptor_name":"Drug Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D048909","descriptor_name":"Diabetes Complications","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.2165/00003495-200060050-00009","doi":"https://doi.org/10.2165/00003495-200060050-00009","is_oa":false,"landing_page_url":"https://doi.org/10.2165/00003495-200060050-00009","pdf_url":null,"source":{"id":"https://openalex.org/S4436492","display_name":"Drugs","issn_l":"0012-6667","issn":["0012-6667","1179-1950"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320330","host_organization_name":"Adis, Springer Healthcare","host_organization_lineage":["https://openalex.org/P4310320330","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Adis, Springer Healthcare","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drugs","raw_type":"journal-article"},{"id":"pmid:11129125","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11129125","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drugs","raw_type":"Journal Article"},{"id":"pmid:11693466","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11693466","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drugs","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9922999739646912}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":80,"referenced_works":["https://openalex.org/W44171809","https://openalex.org/W53561550","https://openalex.org/W57793719","https://openalex.org/W106741180","https://openalex.org/W110305220","https://openalex.org/W137439897","https://openalex.org/W1492227883","https://openalex.org/W1971027475","https://openalex.org/W1980089653","https://openalex.org/W1980901148","https://openalex.org/W1984270203","https://openalex.org/W1986069303","https://openalex.org/W1988412215","https://openalex.org/W1988715948","https://openalex.org/W1989433812","https://openalex.org/W1989877073","https://openalex.org/W1990580370","https://openalex.org/W1995011685","https://openalex.org/W2000542731","https://openalex.org/W2004198435","https://openalex.org/W2007544919","https://openalex.org/W2009535131","https://openalex.org/W2009828266","https://openalex.org/W2014237787","https://openalex.org/W2016331541","https://openalex.org/W2018591284","https://openalex.org/W2020148100","https://openalex.org/W2025199348","https://openalex.org/W2026948174","https://openalex.org/W2029458168","https://openalex.org/W2032245107","https://openalex.org/W2038561706","https://openalex.org/W2038830316","https://openalex.org/W2063021713","https://openalex.org/W2063717896","https://openalex.org/W2064997656","https://openalex.org/W2065914185","https://openalex.org/W2067074491","https://openalex.org/W2067185750","https://openalex.org/W2067219190","https://openalex.org/W2068164683","https://openalex.org/W2072135724","https://openalex.org/W2073195987","https://openalex.org/W2075223671","https://openalex.org/W2079985008","https://openalex.org/W2081212371","https://openalex.org/W2090121327","https://openalex.org/W2094879598","https://openalex.org/W2096179486","https://openalex.org/W2106447874","https://openalex.org/W2109861453","https://openalex.org/W2118194784","https://openalex.org/W2125977155","https://openalex.org/W2133428408","https://openalex.org/W2165209379","https://openalex.org/W2312977127","https://openalex.org/W2315813223","https://openalex.org/W2322213258","https://openalex.org/W2329101404","https://openalex.org/W2330553044","https://openalex.org/W2338878672","https://openalex.org/W2341534273","https://openalex.org/W2394486757","https://openalex.org/W2396775118","https://openalex.org/W2399522484","https://openalex.org/W2400380409","https://openalex.org/W2405767823","https://openalex.org/W2408002194","https://openalex.org/W2414167269","https://openalex.org/W2416041003","https://openalex.org/W2417986195","https://openalex.org/W2418665131","https://openalex.org/W2418723309","https://openalex.org/W2427682747","https://openalex.org/W2428221346","https://openalex.org/W2559924875","https://openalex.org/W3080346889","https://openalex.org/W3156103205","https://openalex.org/W4239889547","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W1995011685","https://openalex.org/W1944683097","https://openalex.org/W4404880533","https://openalex.org/W7099791158","https://openalex.org/W2289981216","https://openalex.org/W2366389905","https://openalex.org/W4236685033","https://openalex.org/W2072135724","https://openalex.org/W4300910241","https://openalex.org/W2120825093"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}