{"id":"https://openalex.org/W2012185417","doi":"https://doi.org/10.1016/s0021-9975(08)80199-5","title":"C cell hyperplasia and carcinoma developing in sheep with experimentally-induced lymphosarcoma","display_name":"C cell hyperplasia and carcinoma developing in sheep with experimentally-induced lymphosarcoma","publication_year":1991,"publication_date":"1991-10-01","ids":{"openalex":"https://openalex.org/W2012185417","doi":"https://doi.org/10.1016/s0021-9975(08)80199-5","mag":"2012185417","pmid":"https://pubmed.ncbi.nlm.nih.gov/1662237"},"language":"en","primary_location":{"id":"doi:10.1016/s0021-9975(08)80199-5","doi":"https://doi.org/10.1016/s0021-9975(08)80199-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0021-9975(08)80199-5","pdf_url":null,"source":{"id":"https://openalex.org/S177502829","display_name":"Journal of Comparative Pathology","issn_l":"0021-9975","issn":["0021-9975","1532-3129"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Comparative Pathology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102723339","display_name":"Hiroyuki M. OKADA","orcid":"https://orcid.org/0000-0003-3251-5853","observed_orcids":["https://orcid.org/0000-0003-3251-5853"]},"institutions":[{"id":"https://openalex.org/I79669737","display_name":"Rakuno Gakuen University","ror":"https://ror.org/014rqt829","country_code":"JP","type":"education","lineage":["https://openalex.org/I79669737"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"H. Okada","raw_affiliation_strings":["Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan","Department of Veterinary Pathology, School of Veterinary Medicine; Rakuno Gakuen University; Ebetsu Hokkaido 069 Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan","institution_ids":["https://openalex.org/I79669737"]},{"raw_affiliation_string":"Department of Veterinary Pathology, School of Veterinary Medicine; Rakuno Gakuen University; Ebetsu Hokkaido 069 Japan","institution_ids":["https://openalex.org/I79669737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111672170","display_name":"Yoshiko Fujimoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205349734","display_name":"Hokkaido University","ror":"https://ror.org/02e16g702","country_code":"JP","type":"education","lineage":["https://openalex.org/I205349734"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Y. Fujimoto","raw_affiliation_strings":["Emeritus Professor of Hokkaido University, Sapporo, Hokkaido 060, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emeritus Professor of Hokkaido University, Sapporo, Hokkaido 060, Japan","institution_ids":["https://openalex.org/I205349734"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044366805","display_name":"Katsuji OHSHIMA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173009982","display_name":"Iwate University","ror":"https://ror.org/04cd75h10","country_code":"JP","type":"education","lineage":["https://openalex.org/I173009982"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"K. Ohshima","raw_affiliation_strings":["Department of Veterinary Pathology, School of Veterinary Medicine, Iwate University, Morioka 020, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Pathology, School of Veterinary Medicine, Iwate University, Morioka 020, Japan","institution_ids":["https://openalex.org/I173009982"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071862017","display_name":"Kiyoshi MATSUKAWA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79669737","display_name":"Rakuno Gakuen University","ror":"https://ror.org/014rqt829","country_code":"JP","type":"education","lineage":["https://openalex.org/I79669737"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"K. Matsukawa","raw_affiliation_strings":["Department of Veterinary Pathology, School of Veterinary Medicine; Rakuno Gakuen University; Ebetsu Hokkaido 069 Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Pathology, School of Veterinary Medicine; Rakuno Gakuen University; Ebetsu Hokkaido 069 Japan","institution_ids":["https://openalex.org/I79669737"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3520,"currency":"USD","value_usd":3520},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.16216216,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"105","issue":"3","first_page":"313","last_page":"322"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11149","display_name":"Veterinary Oncology Research","score":0.5253999829292297,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11149","display_name":"Veterinary Oncology Research","score":0.5253999829292297,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10329","display_name":"Thyroid Cancer Diagnosis and Treatment","score":0.4081999957561493,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11580","display_name":"Veterinary Medicine and Surgery","score":0.0142000000923872,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/c-cell-hyperplasia","display_name":"C-cell hyperplasia","score":0.972000002861023},{"id":"https://openalex.org/keywords/c-cell-carcinoma","display_name":"C-cell carcinoma","score":0.9810000061988831},{"id":"https://openalex.org/keywords/thyroid","display_name":"thyroid gland","score":0.7210000157356262},{"id":"https://openalex.org/keywords/sheep","display_name":"sheep","score":0.6919999718666077},{"id":"https://openalex.org/keywords/lymphosarcoma","display_name":"lymphosarcoma","score":0.8809999823570251},{"id":"https://openalex.org/keywords/calcitonin","display_name":"calcitonin","score":0.8080000281333923},{"id":"https://openalex.org/keywords/calcitonin-gene-related-peptide","display_name":"calcitonin gene-related peptide","score":0.9929999709129333},{"id":"https://openalex.org/keywords/chromogranin-a","display_name":"chromogranin A","score":0.996999979019165},{"id":"https://openalex.org/keywords/neuron-specific-enolase","display_name":"neuron-specific enolase","score":0.9679999947547913},{"id":"https://openalex.org/keywords/secretory-granules","display_name":"secretory granules","score":0.9309999942779541},{"id":"https://openalex.org/keywords/serum-calcium","display_name":"serum calcium","score":0.7149999737739563},{"id":"https://openalex.org/keywords/amyloid-deposition","display_name":"amyloid deposition","score":0.7379999756813049},{"id":"https://openalex.org/keywords/multiple-endocrine-neoplasia","display_name":"multiple endocrine neoplasia","score":0.9139999747276306},{"id":"https://openalex.org/keywords/ultrastructure","display_name":"ultrastructure","score":0.5130000114440918}],"concepts":[{"id":"https://openalex.org/C77231918","wikidata":"https://www.wikidata.org/wiki/Q3698322","display_name":"Chromogranin A","level":3,"score":0.7885507345199585},{"id":"https://openalex.org/C2779627488","wikidata":"https://www.wikidata.org/wiki/Q315860","display_name":"Calcitonin","level":2,"score":0.7738964557647705},{"id":"https://openalex.org/C2777562237","wikidata":"https://www.wikidata.org/wiki/Q835051","display_name":"Hyperplasia","level":2,"score":0.7257475256919861},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.640072226524353},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.5833500623703003},{"id":"https://openalex.org/C190062978","wikidata":"https://www.wikidata.org/wiki/Q79899","display_name":"Cytoplasm","level":2,"score":0.4702039361000061},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.4663521349430084},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.4416988790035248},{"id":"https://openalex.org/C103395026","wikidata":"https://www.wikidata.org/wiki/Q5380231","display_name":"Enteroendocrine cell","level":4,"score":0.4267841875553131},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36078548431396484},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.34335100650787354},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3378334641456604},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.29713284969329834},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.24239277839660645},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.08595755696296692},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.06890955567359924},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001909","descriptor_name":"Leukemia Virus, Bovine","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006965","descriptor_name":"Hyperplasia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008228","descriptor_name":"Lymphoma, Non-Hodgkin","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009378","descriptor_name":"Neoplasms, Multiple Primary","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D009378","descriptor_name":"Neoplasms, Multiple Primary","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009378","descriptor_name":"Neoplasms, Multiple Primary","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012757","descriptor_name":"Sheep Diseases","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D012757","descriptor_name":"Sheep Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D013961","descriptor_name":"Thyroid Gland","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013964","descriptor_name":"Thyroid Neoplasms","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0021-9975(08)80199-5","doi":"https://doi.org/10.1016/s0021-9975(08)80199-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0021-9975(08)80199-5","pdf_url":null,"source":{"id":"https://openalex.org/S177502829","display_name":"Journal of Comparative Pathology","issn_l":"0021-9975","issn":["0021-9975","1532-3129"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Comparative Pathology","raw_type":"journal-article"},{"id":"pmid:1662237","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1662237","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of comparative pathology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W32885507","https://openalex.org/W39231574","https://openalex.org/W177586398","https://openalex.org/W187123369","https://openalex.org/W1471266385","https://openalex.org/W1664001086","https://openalex.org/W1901720315","https://openalex.org/W1906014200","https://openalex.org/W1964481712","https://openalex.org/W1966042926","https://openalex.org/W1971321047","https://openalex.org/W1975707095","https://openalex.org/W1981934184","https://openalex.org/W1986827198","https://openalex.org/W1996921456","https://openalex.org/W1997770515","https://openalex.org/W1998864078","https://openalex.org/W2032433209","https://openalex.org/W2036227659","https://openalex.org/W2049504490","https://openalex.org/W2052577645","https://openalex.org/W2062082681","https://openalex.org/W2074371218","https://openalex.org/W2082736802","https://openalex.org/W2085074491","https://openalex.org/W2112739109","https://openalex.org/W2113824699","https://openalex.org/W2123651874","https://openalex.org/W2126003951","https://openalex.org/W2143302877","https://openalex.org/W2155470839","https://openalex.org/W2158510116","https://openalex.org/W2273508797","https://openalex.org/W2316758973","https://openalex.org/W2323916369","https://openalex.org/W2329553500","https://openalex.org/W2396681525","https://openalex.org/W2408317917","https://openalex.org/W2412921066","https://openalex.org/W2416240959","https://openalex.org/W6644025105"],"related_works":["https://openalex.org/W2611921716","https://openalex.org/W2417547817","https://openalex.org/W7036708074","https://openalex.org/W2334304579","https://openalex.org/W1983181954","https://openalex.org/W1664001086","https://openalex.org/W2035003798","https://openalex.org/W142730825","https://openalex.org/W2468511502","https://openalex.org/W2323916369"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}