{"id":"https://openalex.org/W2012183591","doi":"https://doi.org/10.1039/c3an00383c","title":"Toward optimal spatial and spectral quality in widefield infrared spectromicroscopy of IR labelled single cells","display_name":"Toward optimal spatial and spectral quality in widefield infrared spectromicroscopy of IR labelled single cells","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2012183591","doi":"https://doi.org/10.1039/c3an00383c","mag":"2012183591","pmid":"https://pubmed.ncbi.nlm.nih.gov/23826609"},"language":"en","primary_location":{"id":"doi:10.1039/c3an00383c","doi":"https://doi.org/10.1039/c3an00383c","is_oa":true,"landing_page_url":"https://doi.org/10.1039/c3an00383c","pdf_url":"https://pubs.rsc.org/en/content/articlepdf/2013/an/c3an00383c","source":{"id":"https://openalex.org/S105746325","display_name":"The Analyst","issn_l":"0003-2654","issn":["0003-2654","1364-5528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Analyst","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://pubs.rsc.org/en/content/articlepdf/2013/an/c3an00383c","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102914413","display_name":"Eric C. Mattson","orcid":"https://orcid.org/0000-0002-0755-2583","observed_orcids":["https://orcid.org/0000-0002-0755-2583"]},"institutions":[{"id":"https://openalex.org/I43579087","display_name":"University of Wisconsin\u2013Milwaukee","ror":"https://ror.org/031q21x57","country_code":"US","type":"education","lineage":["https://openalex.org/I43579087"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric C. Mattson","raw_affiliation_strings":["Physics Dept., University of Wisconsin-Milwaukee, Milwaukee, WI, USA. cjhirsch@uwm.edu","Physics Department, University of Wisconsin-Milwaukee, Milwaukee, WI, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physics Dept., University of Wisconsin-Milwaukee, Milwaukee, WI, USA. cjhirsch@uwm.edu","institution_ids":["https://openalex.org/I43579087"]},{"raw_affiliation_string":"Physics Department, University of Wisconsin-Milwaukee, Milwaukee, WI, USA","institution_ids":["https://openalex.org/I43579087"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103860010","display_name":"Miriam V. Unger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I43579087","display_name":"University of Wisconsin\u2013Milwaukee","ror":"https://ror.org/031q21x57","country_code":"US","type":"education","lineage":["https://openalex.org/I43579087"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Miriam Unger","raw_affiliation_strings":["Physics Dept., University of Wisconsin-Milwaukee, Milwaukee, WI, USA","Physics Dept., University of Wisconsin-Milwaukee,Milwaukee,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physics Dept., University of Wisconsin-Milwaukee, Milwaukee, WI, USA","institution_ids":["https://openalex.org/I43579087"]},{"raw_affiliation_string":"Physics Dept., University of Wisconsin-Milwaukee,Milwaukee,USA","institution_ids":["https://openalex.org/I43579087"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049194765","display_name":"Sylvain Cl\u00e8de","orcid":"https://orcid.org/0009-0008-3075-650X","observed_orcids":["https://orcid.org/0009-0008-3075-650X"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I29607241","display_name":"\u00c9cole Normale Sup\u00e9rieure - PSL","ror":"https://ror.org/05a0dhs15","country_code":"FR","type":"other","lineage":["https://openalex.org/I2746051580","https://openalex.org/I29607241"]},{"id":"https://openalex.org/I4210165010","display_name":"Laboratoire des Biomol\u00e9cules","ror":"https://ror.org/05vd6h165","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I2746051580","https://openalex.org/I29607241","https://openalex.org/I39804081","https://openalex.org/I4210128300","https://openalex.org/I4210165010","https://openalex.org/I4405257589"]},{"id":"https://openalex.org/I4405264447","display_name":"Universit\u00e9 Pierre-et-Marie-Curie","ror":"https://ror.org/01yvrd251","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081","https://openalex.org/I4405264447"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sylvain Cl\u00e8de","raw_affiliation_strings":["Ecole Normale Sup\u00e9rieure, D\u00e9partement de chimie, 24, rue Lhomond, 75005 Paris, France","LBM, CNRS, UMR7203, France","Universit\u00e9 Pierre et Marie Curie Paris 6, 4, Place Jussieu, 75005 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ecole Normale Sup\u00e9rieure, D\u00e9partement de chimie, 24, rue Lhomond, 75005 Paris, France","institution_ids":["https://openalex.org/I29607241"]},{"raw_affiliation_string":"LBM, CNRS, UMR7203, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210165010"]},{"raw_affiliation_string":"Universit\u00e9 Pierre et Marie Curie Paris 6, 4, Place Jussieu, 75005 Paris, France","institution_ids":["https://openalex.org/I4405264447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032847726","display_name":"Fran\u00e7ois Lambert","orcid":"https://orcid.org/0000-0002-8655-2652","observed_orcids":["https://orcid.org/0000-0002-8655-2652"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I29607241","display_name":"\u00c9cole Normale Sup\u00e9rieure - PSL","ror":"https://ror.org/05a0dhs15","country_code":"FR","type":"other","lineage":["https://openalex.org/I2746051580","https://openalex.org/I29607241"]},{"id":"https://openalex.org/I4210165010","display_name":"Laboratoire des Biomol\u00e9cules","ror":"https://ror.org/05vd6h165","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I2746051580","https://openalex.org/I29607241","https://openalex.org/I39804081","https://openalex.org/I4210128300","https://openalex.org/I4210165010","https://openalex.org/I4405257589"]},{"id":"https://openalex.org/I4405264447","display_name":"Universit\u00e9 Pierre-et-Marie-Curie","ror":"https://ror.org/01yvrd251","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081","https://openalex.org/I4405264447"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Fran\u00e7ois Lambert","raw_affiliation_strings":["Ecole Normale Sup\u00e9rieure, D\u00e9partement de chimie, 24, rue Lhomond, 75005 Paris, France","LBM, CNRS, UMR7203, France","Universit\u00e9 Pierre et Marie Curie Paris 6, 4, Place Jussieu, 75005 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ecole Normale Sup\u00e9rieure, D\u00e9partement de chimie, 24, rue Lhomond, 75005 Paris, France","institution_ids":["https://openalex.org/I29607241"]},{"raw_affiliation_string":"LBM, CNRS, UMR7203, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210165010"]},{"raw_affiliation_string":"Universit\u00e9 Pierre et Marie Curie Paris 6, 4, Place Jussieu, 75005 Paris, France","institution_ids":["https://openalex.org/I4405264447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069121068","display_name":"Clotilde Policar","orcid":"https://orcid.org/0000-0003-0255-1650","observed_orcids":["https://orcid.org/0000-0003-0255-1650"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I29607241","display_name":"\u00c9cole Normale Sup\u00e9rieure - PSL","ror":"https://ror.org/05a0dhs15","country_code":"FR","type":"other","lineage":["https://openalex.org/I2746051580","https://openalex.org/I29607241"]},{"id":"https://openalex.org/I4210165010","display_name":"Laboratoire des Biomol\u00e9cules","ror":"https://ror.org/05vd6h165","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I2746051580","https://openalex.org/I29607241","https://openalex.org/I39804081","https://openalex.org/I4210128300","https://openalex.org/I4210165010","https://openalex.org/I4405257589"]},{"id":"https://openalex.org/I4405264447","display_name":"Universit\u00e9 Pierre-et-Marie-Curie","ror":"https://ror.org/01yvrd251","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081","https://openalex.org/I4405264447"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Clotilde Policar","raw_affiliation_strings":["Ecole Normale Sup\u00e9rieure, D\u00e9partement de chimie, 24, rue Lhomond, 75005 Paris, France","LBM, CNRS, UMR7203, France","Universit\u00e9 Pierre et Marie Curie Paris 6, 4, Place Jussieu, 75005 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ecole Normale Sup\u00e9rieure, D\u00e9partement de chimie, 24, rue Lhomond, 75005 Paris, France","institution_ids":["https://openalex.org/I29607241"]},{"raw_affiliation_string":"LBM, CNRS, UMR7203, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210165010"]},{"raw_affiliation_string":"Universit\u00e9 Pierre et Marie Curie Paris 6, 4, Place Jussieu, 75005 Paris, France","institution_ids":["https://openalex.org/I4405264447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064390055","display_name":"Asher Imtiaz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I43579087","display_name":"University of Wisconsin\u2013Milwaukee","ror":"https://ror.org/031q21x57","country_code":"US","type":"education","lineage":["https://openalex.org/I43579087"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Asher Imtiaz","raw_affiliation_strings":["Mechanical Engineering Dept., University of Wisconsin-Milwaukee, Milwaukee, WI, USA","Mechanical Engineering Department, University of Wisconsin-Milwaukee, Milwaukee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mechanical Engineering Dept., University of Wisconsin-Milwaukee, Milwaukee, WI, USA","institution_ids":["https://openalex.org/I43579087"]},{"raw_affiliation_string":"Mechanical Engineering Department, University of Wisconsin-Milwaukee, Milwaukee, USA","institution_ids":["https://openalex.org/I43579087"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101690002","display_name":"Roshan M. D\u2019Souza","orcid":"https://orcid.org/0000-0001-5598-7218","observed_orcids":["https://orcid.org/0000-0001-5598-7218"]},"institutions":[{"id":"https://openalex.org/I43579087","display_name":"University of Wisconsin\u2013Milwaukee","ror":"https://ror.org/031q21x57","country_code":"US","type":"education","lineage":["https://openalex.org/I43579087"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roshan D'Souza","raw_affiliation_strings":["Mechanical Engineering Dept., University of Wisconsin-Milwaukee, Milwaukee, WI, USA","Mechanical Engineering Department, University of Wisconsin-Milwaukee, Milwaukee, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mechanical Engineering Dept., University of Wisconsin-Milwaukee, Milwaukee, WI, USA","institution_ids":["https://openalex.org/I43579087"]},{"raw_affiliation_string":"Mechanical Engineering Department, University of Wisconsin-Milwaukee, Milwaukee, USA","institution_ids":["https://openalex.org/I43579087"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020363466","display_name":"Carol J. Hirschmugl","orcid":"https://orcid.org/0000-0002-9328-0667","observed_orcids":["https://orcid.org/0000-0002-9328-0667"]},"institutions":[{"id":"https://openalex.org/I43579087","display_name":"University of Wisconsin\u2013Milwaukee","ror":"https://ror.org/031q21x57","country_code":"US","type":"education","lineage":["https://openalex.org/I43579087"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Carol J. Hirschmugl","raw_affiliation_strings":["Physics Dept., University of Wisconsin-Milwaukee, Milwaukee, WI, USA","Physics Dept., University of Wisconsin-Milwaukee,Milwaukee,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physics Dept., University of Wisconsin-Milwaukee, Milwaukee, WI, USA","institution_ids":["https://openalex.org/I43579087"]},{"raw_affiliation_string":"Physics Dept., University of Wisconsin-Milwaukee,Milwaukee,USA","institution_ids":["https://openalex.org/I43579087"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5020363466"],"corresponding_institution_ids":["https://openalex.org/I43579087"],"apc_list":null,"apc_paid":null,"fwci":2.1258,"has_fulltext":true,"cited_by_count":36,"citation_normalized_percentile":{"value":0.85815076,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"138","issue":"19","first_page":"5610","last_page":"5610"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10640","display_name":"Spectroscopy and Chemometric Analyses","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11212","display_name":"Cultural Heritage Materials Analysis","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1204","display_name":"Archeology (arts and humanities)"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/spatial-oversampling","display_name":"spatial oversampling","score":0.6990000009536743},{"id":"https://openalex.org/keywords/deconvolution","display_name":"deconvolution","score":0.6380000114440918},{"id":"https://openalex.org/keywords/point-spread-function","display_name":"point spread function","score":0.9150000214576721},{"id":"https://openalex.org/keywords/spectral-preprocessing","display_name":"spectral preprocessing","score":0.871999979019165},{"id":"https://openalex.org/keywords/single-cell-imaging","display_name":"single-cell imaging","score":0.35600000619888306}],"concepts":[{"id":"https://openalex.org/C65597285","wikidata":"https://www.wikidata.org/wiki/Q5090469","display_name":"Chemical imaging","level":3,"score":0.8130972385406494},{"id":"https://openalex.org/C159078339","wikidata":"https://www.wikidata.org/wiki/Q959005","display_name":"Hyperspectral imaging","level":2,"score":0.7382057905197144},{"id":"https://openalex.org/C158355884","wikidata":"https://www.wikidata.org/wiki/Q11388","display_name":"Infrared","level":2,"score":0.6069717407226562},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.5271115899085999},{"id":"https://openalex.org/C160892712","wikidata":"https://www.wikidata.org/wiki/Q901559","display_name":"Fourier transform infrared spectroscopy","level":2,"score":0.4917295277118683},{"id":"https://openalex.org/C21368211","wikidata":"https://www.wikidata.org/wiki/Q689863","display_name":"Synchrotron","level":2,"score":0.4795001149177551},{"id":"https://openalex.org/C2987860518","wikidata":"https://www.wikidata.org/wiki/Q1074953","display_name":"Infrared microscopy","level":3,"score":0.4353805184364319},{"id":"https://openalex.org/C197323446","wikidata":"https://www.wikidata.org/wiki/Q331222","display_name":"Oversampling","level":3,"score":0.4208492338657379},{"id":"https://openalex.org/C205372480","wikidata":"https://www.wikidata.org/wiki/Q210521","display_name":"Image resolution","level":2,"score":0.42079320549964905},{"id":"https://openalex.org/C145406643","wikidata":"https://www.wikidata.org/wiki/Q2641959","display_name":"Raster scan","level":2,"score":0.4199146032333374},{"id":"https://openalex.org/C102519508","wikidata":"https://www.wikidata.org/wiki/Q6520159","display_name":"Fourier transform","level":2,"score":0.41802138090133667},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4173273742198944},{"id":"https://openalex.org/C158479148","wikidata":"https://www.wikidata.org/wiki/Q609991","display_name":"Imaging spectroscopy","level":3,"score":0.415897935628891},{"id":"https://openalex.org/C3232514","wikidata":"https://www.wikidata.org/wiki/Q7575196","display_name":"Spectral imaging","level":2,"score":0.4156862199306488},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.39029088616371155},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.3014522194862366},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2660718560218811},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.1698506474494934},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.13778626918792725},{"id":"https://openalex.org/C46362747","wikidata":"https://www.wikidata.org/wiki/Q173431","display_name":"CMOS","level":2,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007424","descriptor_name":"Intracellular Fluid","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D017550","descriptor_name":"Spectroscopy, Fourier Transform Infrared","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1039/c3an00383c","doi":"https://doi.org/10.1039/c3an00383c","is_oa":true,"landing_page_url":"https://doi.org/10.1039/c3an00383c","pdf_url":"https://pubs.rsc.org/en/content/articlepdf/2013/an/c3an00383c","source":{"id":"https://openalex.org/S105746325","display_name":"The Analyst","issn_l":"0003-2654","issn":["0003-2654","1364-5528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Analyst","raw_type":"journal-article"},{"id":"pmid:23826609","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23826609","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Analyst","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-00841517v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-00841517v1/document","pdf_url":"https://hal.science/hal-00841517v1/file/C3AN00383C.pdf","source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Analyst, 2013, 138 (19), pp.5610-5618. ⟨10.1039/c3an00383c⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1039/c3an00383c","doi":"https://doi.org/10.1039/c3an00383c","is_oa":true,"landing_page_url":"https://doi.org/10.1039/c3an00383c","pdf_url":"https://pubs.rsc.org/en/content/articlepdf/2013/an/c3an00383c","source":{"id":"https://openalex.org/S105746325","display_name":"The Analyst","issn_l":"0003-2654","issn":["0003-2654","1364-5528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Analyst","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3405068560","display_name":"MRI: Development of Synchrotron Based Infrared Microspectroscopy with a Multi-Element Detector","funder_award_id":"0619759","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G5369473451","display_name":"Collaborative Research: Advancing In-vivo Chemical Imaging by Merging Synchrotron-Based Infrared Data, Rapid Spectral Image Analysis, and Quantitative Chemometrics","funder_award_id":"1112433","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G8243507912","display_name":null,"funder_award_id":"CHE-1112433","funder_id":"https://openalex.org/F4320337393","funder_display_name":"Division of Chemistry"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320337367","display_name":"Division of Materials Research","ror":"https://ror.org/01pc7k308"},{"id":"https://openalex.org/F4320337393","display_name":"Division of Chemistry","ror":"https://ror.org/01ar8dr59"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2012183591.pdf","grobid_xml":"https://content.openalex.org/works/W2012183591.grobid-xml"},"referenced_works_count":32,"referenced_works":["https://openalex.org/W1976660395","https://openalex.org/W1987955706","https://openalex.org/W1992655034","https://openalex.org/W2008071996","https://openalex.org/W2008674896","https://openalex.org/W2011032033","https://openalex.org/W2011238330","https://openalex.org/W2014466025","https://openalex.org/W2020933885","https://openalex.org/W2027322045","https://openalex.org/W2027444499","https://openalex.org/W2043197681","https://openalex.org/W2048356821","https://openalex.org/W2055400038","https://openalex.org/W2076814295","https://openalex.org/W2079248766","https://openalex.org/W2086329466","https://openalex.org/W2099441762","https://openalex.org/W2129169938","https://openalex.org/W2131207623","https://openalex.org/W2139522708","https://openalex.org/W2142773345","https://openalex.org/W2147970793","https://openalex.org/W2149498770","https://openalex.org/W2159920173","https://openalex.org/W2160224564","https://openalex.org/W2161921805","https://openalex.org/W2165871985","https://openalex.org/W2167273463","https://openalex.org/W2169288390","https://openalex.org/W2170034127","https://openalex.org/W2327055006"],"related_works":["https://openalex.org/W2048356821","https://openalex.org/W1992655034","https://openalex.org/W1977448398","https://openalex.org/W2120119943","https://openalex.org/W1981743112","https://openalex.org/W2088260822","https://openalex.org/W1970448845","https://openalex.org/W1987955706","https://openalex.org/W2327055006","https://openalex.org/W2035587056"],"abstract_inverted_index":{"Advancements":[0],"in":[1,58,179,216],"widefield":[2],"infrared":[3,20,73,183,188],"spectromicroscopy":[4],"have":[5],"recently":[6],"been":[7],"demonstrated":[8],"following":[9],"the":[10,26,34,46,122,130,137,163,174,217],"commissioning":[11],"of":[12,36,51,121,158,162],"IRENI":[13],"(InfraRed":[14],"ENvironmental":[15],"Imaging),":[16],"a":[17,59],"Fourier":[18],"Transform":[19],"(FTIR)":[21],"chemical":[22,156],"imaging":[23,74,123],"beamline":[24],"at":[25,82],"Synchrotron":[27],"Radiation":[28],"Center.":[29],"The":[30,119,187],"present":[31],"study":[32],"demonstrates":[33],"effects":[35],"magnification,":[37],"spatial":[38,69],"oversampling,":[39],"spectral":[40,160,199],"pre-processing":[41,200],"and":[42,49,88,92,102,111,166,176,184,192,207],"deconvolution,":[43],"focusing":[44],"on":[45],"intracellular":[47],"detection":[48],"distribution":[50],"an":[52],"exogenous":[53],"metal":[54],"tris-carbonyl":[55],"derivative":[56],"1":[57,165,169],"single":[60],"MDA-MB-231":[61],"breast":[62],"cancer":[63],"cell.":[64],"We":[65],"demonstrate":[66],"here":[67],"that":[68,133,168],"oversampling":[70],"for":[71,95,115,147],"synchrotron-based":[72],"is":[75,134,141,170],"critical":[76],"to":[77,108,112,173,212],"obtain":[78],"accurate":[79],"diffraction-limited":[80],"images":[81,94,157],"all":[83],"wavelengths":[84],"simultaneously.":[85],"Resolution":[86],"criteria":[87],"results":[89],"from":[90],"raw":[91],"deconvoluted":[93],"two":[96],"Schwarzschild":[97],"objectives":[98],"(36\u00d7,":[99],"NA":[100,104],"0.5":[101],"74\u00d7,":[103],"0.65)":[105],"are":[106,194],"compared":[107],"each":[109],"other":[110],"prior":[113],"reports":[114],"raster-scanned,":[116],"confocal":[117],"microscopes.":[118],"resolution":[120],"data":[124],"can":[125],"be":[126],"improved":[127,195],"by":[128],"deconvolving":[129],"instrumental":[131],"broadening":[132],"determined":[135],"with":[136,143,181],"measured":[138],"PSFs,":[139],"which":[140],"implemented":[142],"GPU":[144],"programming":[145],"architecture":[146],"fast":[148],"hyperspectral":[149,218],"processing.":[150],"High":[151],"definition,":[152],"rapidly":[153],"acquired,":[154],"FTIR":[155],"respective":[159],"signatures":[161],"cell":[164],"shows":[167],"localized":[171],"next":[172],"phosphate-":[175],"Amide-rich":[177],"regions,":[178],"agreement":[180],"previous":[182],"luminescence":[185],"studies.":[186],"image":[189],"contrast,":[190],"localization":[191],"definition":[193],"after":[196],"applying":[197],"proven":[198],"(principal":[201],"component":[202],"analysis":[203],"based":[204],"noise":[205],"reduction":[206],"RMie":[208],"scattering":[209],"correction":[210],"algorithms)":[211],"individual":[213],"pixel":[214],"spectra":[215],"cube.":[219]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}