{"id":"https://openalex.org/W2012179823","doi":"https://doi.org/10.1155/2012/750891","title":"Current State-of-Art and New Trends on Lipid Nanoparticles (SLN and NLC) for Oral Drug Delivery","display_name":"Current State-of-Art and New Trends on Lipid Nanoparticles (SLN and NLC) for Oral Drug Delivery","publication_year":2011,"publication_date":"2011-11-24","ids":{"openalex":"https://openalex.org/W2012179823","doi":"https://doi.org/10.1155/2012/750891","mag":"2012179823","pmid":"https://pubmed.ncbi.nlm.nih.gov/22175030","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3228282"},"language":"en","primary_location":{"id":"doi:10.1155/2012/750891","doi":"https://doi.org/10.1155/2012/750891","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2012/750891","pdf_url":"https://downloads.hindawi.com/archive/2012/750891.pdf","source":{"id":"https://openalex.org/S2764829945","display_name":"Journal of Drug Delivery","issn_l":"2090-3022","issn":["2090-3022","2090-3014"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","poland-20"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Drug Delivery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://downloads.hindawi.com/archive/2012/750891.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082291455","display_name":"Patr\u00edcia B. Severino","orcid":"https://orcid.org/0000-0001-6527-6612","observed_orcids":["https://orcid.org/0000-0001-6527-6612"]},"institutions":[{"id":"https://openalex.org/I157071867","display_name":"Fernando Pessoa University","ror":"https://ror.org/04h8e7606","country_code":"PT","type":"education","lineage":["https://openalex.org/I157071867"]},{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR","PT"],"is_corresponding":false,"raw_author_name":"Patr\u00edcia Severino","raw_affiliation_strings":["Department of Biotechnological Processes, School of Chemical Engineering, State University of Campinas (UNICAMP), 13083-970 Campinas, SP, Brazil","Faculty of Health Sciences, Fernando Pessoa University (FCS-UFP), Rua Carlos da Maia, 296, 4200-150 Porto, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnological Processes, School of Chemical Engineering, State University of Campinas (UNICAMP), 13083-970 Campinas, SP, Brazil","institution_ids":["https://openalex.org/I181391015"]},{"raw_affiliation_string":"Faculty of Health Sciences, Fernando Pessoa University (FCS-UFP), Rua Carlos da Maia, 296, 4200-150 Porto, Portugal","institution_ids":["https://openalex.org/I157071867"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016516113","display_name":"Tatiana Andreani","orcid":"https://orcid.org/0000-0002-3794-8159","observed_orcids":["https://orcid.org/0000-0002-3794-8159"]},"institutions":[{"id":"https://openalex.org/I155381812","display_name":"University of Tr\u00e1s-os-Montes and Alto Douro","ror":"https://ror.org/03qc8vh97","country_code":"PT","type":"education","lineage":["https://openalex.org/I155381812"]},{"id":"https://openalex.org/I157071867","display_name":"Fernando Pessoa University","ror":"https://ror.org/04h8e7606","country_code":"PT","type":"education","lineage":["https://openalex.org/I157071867"]},{"id":"https://openalex.org/I4405254181","display_name":"Centro de Investiga\u00e7\u00e3o e de Tecnologias Agro-Ambientais e Biologicas","ror":"https://ror.org/01h1p3y81","country_code":"PT","type":"facility","lineage":["https://openalex.org/I155381812","https://openalex.org/I4405254181"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Tatiana Andreani","raw_affiliation_strings":["Centre for Research and Technology of Agro-Environmental and Biological Sciences, 5001-801 Vila Real, Portugal","Department of Biology and Environment, University of Tr\u00e1s-os Montes e Alto Douro, 5001-801 Vila Real, Portugal","Faculty of Health Sciences, Fernando Pessoa University (FCS-UFP), Rua Carlos da Maia, 296, 4200-150 Porto, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Research and Technology of Agro-Environmental and Biological Sciences, 5001-801 Vila Real, Portugal","institution_ids":["https://openalex.org/I4405254181"]},{"raw_affiliation_string":"Department of Biology and Environment, University of Tr\u00e1s-os Montes e Alto Douro, 5001-801 Vila Real, Portugal","institution_ids":["https://openalex.org/I155381812"]},{"raw_affiliation_string":"Faculty of Health Sciences, Fernando Pessoa University (FCS-UFP), Rua Carlos da Maia, 296, 4200-150 Porto, Portugal","institution_ids":["https://openalex.org/I157071867"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045843520","display_name":"Ana Sofia Macedo","orcid":"https://orcid.org/0000-0002-7018-7478","observed_orcids":["https://orcid.org/0000-0002-7018-7478"]},"institutions":[{"id":"https://openalex.org/I157071867","display_name":"Fernando Pessoa University","ror":"https://ror.org/04h8e7606","country_code":"PT","type":"education","lineage":["https://openalex.org/I157071867"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Ana Sofia Macedo","raw_affiliation_strings":["Faculty of Health Sciences, Fernando Pessoa University (FCS-UFP), Rua Carlos da Maia, 296, 4200-150 Porto, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, Fernando Pessoa University (FCS-UFP), Rua Carlos da Maia, 296, 4200-150 Porto, Portugal","institution_ids":["https://openalex.org/I157071867"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075200094","display_name":"Joana F. Fangueiro","orcid":"https://orcid.org/0000-0001-6544-3943","observed_orcids":["https://orcid.org/0000-0001-6544-3943"]},"institutions":[{"id":"https://openalex.org/I157071867","display_name":"Fernando Pessoa University","ror":"https://ror.org/04h8e7606","country_code":"PT","type":"education","lineage":["https://openalex.org/I157071867"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Joana F. Fangueiro","raw_affiliation_strings":["Faculty of Health Sciences, Fernando Pessoa University (FCS-UFP), Rua Carlos da Maia, 296, 4200-150 Porto, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, Fernando Pessoa University (FCS-UFP), Rua Carlos da Maia, 296, 4200-150 Porto, Portugal","institution_ids":["https://openalex.org/I157071867"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077901406","display_name":"Maria Helena Andrade Santana","orcid":"https://orcid.org/0000-0002-2258-4911","observed_orcids":["https://orcid.org/0000-0002-2258-4911"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Maria Helena A. Santana","raw_affiliation_strings":["Department of Biotechnological Processes, School of Chemical Engineering, State University of Campinas (UNICAMP), 13083-970 Campinas, SP, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnological Processes, School of Chemical Engineering, State University of Campinas (UNICAMP), 13083-970 Campinas, SP, Brazil","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009381122","display_name":"Am\u00e9lia Maria Silva","orcid":"https://orcid.org/0000-0002-7524-9914","observed_orcids":["https://orcid.org/0000-0002-7524-9914","https://orcid.org/0000-0003-3387-4487"]},"institutions":[{"id":"https://openalex.org/I155381812","display_name":"University of Tr\u00e1s-os-Montes and Alto Douro","ror":"https://ror.org/03qc8vh97","country_code":"PT","type":"education","lineage":["https://openalex.org/I155381812"]},{"id":"https://openalex.org/I4405254181","display_name":"Centro de Investiga\u00e7\u00e3o e de Tecnologias Agro-Ambientais e Biologicas","ror":"https://ror.org/01h1p3y81","country_code":"PT","type":"facility","lineage":["https://openalex.org/I155381812","https://openalex.org/I4405254181"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Am\u00e9lia M. Silva","raw_affiliation_strings":["Centre for Research and Technology of Agro-Environmental and Biological Sciences, 5001-801 Vila Real, Portugal","Department of Biology and Environment, University of Tr\u00e1s-os Montes e Alto Douro, 5001-801 Vila Real, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Research and Technology of Agro-Environmental and Biological Sciences, 5001-801 Vila Real, Portugal","institution_ids":["https://openalex.org/I4405254181"]},{"raw_affiliation_string":"Department of Biology and Environment, University of Tr\u00e1s-os Montes e Alto Douro, 5001-801 Vila Real, Portugal","institution_ids":["https://openalex.org/I155381812"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072472271","display_name":"Eliana B. Souto","orcid":"https://orcid.org/0000-0002-9737-6017","observed_orcids":["https://orcid.org/0000-0002-9737-6017"]},"institutions":[{"id":"https://openalex.org/I155381812","display_name":"University of Tr\u00e1s-os-Montes and Alto Douro","ror":"https://ror.org/03qc8vh97","country_code":"PT","type":"education","lineage":["https://openalex.org/I155381812"]},{"id":"https://openalex.org/I157071867","display_name":"Fernando Pessoa University","ror":"https://ror.org/04h8e7606","country_code":"PT","type":"education","lineage":["https://openalex.org/I157071867"]},{"id":"https://openalex.org/I4210167387","display_name":"Institute for Biotechnology and Bioengineering","ror":"https://ror.org/05ws8g470","country_code":"PT","type":"facility","lineage":["https://openalex.org/I4210167387"]}],"countries":["PT"],"is_corresponding":true,"raw_author_name":"Eliana B. Souto","raw_affiliation_strings":["Faculty of Health Sciences, Fernando Pessoa University (FCS-UFP), Rua Carlos da Maia, 296, 4200-150 Porto, Portugal","Institute of Biotechnology and Bioengineering, Centre of Genomics and Biotechnology, University of Tr\u00e1s-os-Montes and Alto Douro (CGB-UTAD/IBB), P.O. Box 1013, 5001-801 Vila Real, Portugal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, Fernando Pessoa University (FCS-UFP), Rua Carlos da Maia, 296, 4200-150 Porto, Portugal","institution_ids":["https://openalex.org/I157071867"]},{"raw_affiliation_string":"Institute of Biotechnology and Bioengineering, Centre of Genomics and Biotechnology, University of Tr\u00e1s-os-Montes and Alto Douro (CGB-UTAD/IBB), P.O. Box 1013, 5001-801 Vila Real, Portugal","institution_ids":["https://openalex.org/I155381812","https://openalex.org/I4210167387"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5072472271"],"corresponding_institution_ids":["https://openalex.org/I155381812","https://openalex.org/I157071867","https://openalex.org/I4210167387"],"apc_list":null,"apc_paid":null,"fwci":6.5059,"has_fulltext":true,"cited_by_count":296,"citation_normalized_percentile":{"value":0.97921961,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"2012","issue":null,"first_page":"1","last_page":"10"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.5723000168800354,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.5723000168800354,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.3467000126838684,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.04610000178217888,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lipid-nanoparticles","display_name":"lipid nanoparticles","score":0.9940000176429749},{"id":"https://openalex.org/keywords/solid-lipid-nanoparticles","display_name":"solid lipid nanoparticles","score":0.9599999785423279},{"id":"https://openalex.org/keywords/nanostructured-lipid-carriers","display_name":"nanostructured lipid carriers","score":0.8230000138282776},{"id":"https://openalex.org/keywords/oral-drug-delivery","display_name":"oral drug delivery","score":0.9990000128746033},{"id":"https://openalex.org/keywords/lipid-based-drug-delivery-systems","display_name":"lipid-based drug delivery","score":0.699999988079071},{"id":"https://openalex.org/keywords/gastrointestinal-drug-absorption","display_name":"gastrointestinal drug absorption","score":0.8539999723434448},{"id":"https://openalex.org/keywords/mucoadhesion","display_name":"mucoadhesion","score":0.9330000281333923},{"id":"https://openalex.org/keywords/drug-protection-from-degradation","display_name":"drug protection from degradation","score":0.765999972820282},{"id":"https://openalex.org/keywords/controlled-drug-release","display_name":"controlled drug release","score":0.921999990940094},{"id":"https://openalex.org/keywords/pharmacokinetics","display_name":"pharmacokinetics","score":0.9409999847412109},{"id":"https://openalex.org/keywords/biodegradable-drug-carriers","display_name":"biodegradable drug carriers","score":0.8109999895095825}],"concepts":[{"id":"https://openalex.org/C199529486","wikidata":"https://www.wikidata.org/wiki/Q7557912","display_name":"Solid lipid nanoparticle","level":3,"score":0.8070292472839355},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.6943752765655518},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.6467350125312805},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5930802226066589},{"id":"https://openalex.org/C112705442","wikidata":"https://www.wikidata.org/wiki/Q323936","display_name":"Pharmacokinetics","level":2,"score":0.5747740268707275},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4746849238872528},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.474005788564682},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.31969815492630005},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.22846180200576782},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.20506086945533752},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.10331940650939941}],"mesh":[],"locations_count":7,"locations":[{"id":"doi:10.1155/2012/750891","doi":"https://doi.org/10.1155/2012/750891","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2012/750891","pdf_url":"https://downloads.hindawi.com/archive/2012/750891.pdf","source":{"id":"https://openalex.org/S2764829945","display_name":"Journal of Drug Delivery","issn_l":"2090-3022","issn":["2090-3022","2090-3014"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","poland-20"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Drug Delivery","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2243844","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3228282","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:22175030","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22175030","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of drug delivery","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3228282","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3228282/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Drug Deliv","raw_type":"Text"},{"id":"pmh:oai:repositorio.unicamp.br:REPOSIP/200400","doi":null,"is_oa":true,"landing_page_url":"http://repositorio.unicamp.br/jspui/handle/REPOSIP/200400","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PubMed","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.288.1196","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.288.1196","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/c4/7d/J_Drug_Deliv_2012_Nov_24_2012_750891.tar.gz","raw_type":"text"},{"id":"pmh:oai:americanae.aecid.es:2827496","doi":null,"is_oa":true,"landing_page_url":"http://americanae.aecid.es/americanae/es/registros/registro.do?tipoRegistro=MTD&idBib=2827496","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":{"id":"doi:10.1155/2012/750891","doi":"https://doi.org/10.1155/2012/750891","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2012/750891","pdf_url":"https://downloads.hindawi.com/archive/2012/750891.pdf","source":{"id":"https://openalex.org/S2764829945","display_name":"Journal of Drug Delivery","issn_l":"2090-3022","issn":["2090-3022","2090-3014"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","poland-20"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Drug Delivery","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3613628650","display_name":null,"funder_award_id":"SFRH/BD/60640/2009","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"},{"id":"https://openalex.org/G368410320","display_name":null,"funder_award_id":"SFRH/BD/60640/2009","funder_id":"https://openalex.org/F4320321091","funder_display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior"},{"id":"https://openalex.org/G5426901979","display_name":null,"funder_award_id":"ERA-Eula/0002/2009","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"},{"id":"https://openalex.org/G6574727509","display_name":null,"funder_award_id":"ERA-Eula/0002/2009","funder_id":"https://openalex.org/F4320321091","funder_display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior"},{"id":"https://openalex.org/G7233702660","display_name":"NanoSKIN: Nanopart\u00edculas contendo agentes quimioterap\u00eauticos para terapias inovadoras de doen\u00e7as severas da pele - Leishmaniase muco/cut\u00e2nea e carcinoma espinocelular como exemplos","funder_award_id":"ERA-Eula/0002/2009","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"},{"id":"https://openalex.org/G8105582771","display_name":"INCRETINE PEPTIDE-BASED NANOPARTICLE SCAFFOLDS FOR DIABETES MELLITUS CONTROL AND TREATMENT","funder_award_id":"SFRH/BD/60640/2009","funder_id":"https://openalex.org/F4320334779","funder_display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia"}],"funders":[{"id":"https://openalex.org/F4320320997","display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","ror":"https://ror.org/02ddkpn78"},{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"},{"id":"https://openalex.org/F4320324388","display_name":"Minist\u00e9rio da Ci\u00eancia e Tecnologia","ror":"https://ror.org/050zdnc69"},{"id":"https://openalex.org/F4320334779","display_name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","ror":"https://ror.org/00snfqn58"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2012179823.pdf","grobid_xml":"https://content.openalex.org/works/W2012179823.grobid-xml"},"referenced_works_count":123,"referenced_works":["https://openalex.org/W3651199","https://openalex.org/W32176613","https://openalex.org/W37840549","https://openalex.org/W85362793","https://openalex.org/W88550752","https://openalex.org/W112317081","https://openalex.org/W137791175","https://openalex.org/W232893415","https://openalex.org/W287995008","https://openalex.org/W1236654308","https://openalex.org/W1567006673","https://openalex.org/W1579046626","https://openalex.org/W1880932432","https://openalex.org/W1912284197","https://openalex.org/W1963935732","https://openalex.org/W1964896591","https://openalex.org/W1966057568","https://openalex.org/W1967438326","https://openalex.org/W1968464905","https://openalex.org/W1970541980","https://openalex.org/W1971874586","https://openalex.org/W1971882647","https://openalex.org/W1971907096","https://openalex.org/W1974050571","https://openalex.org/W1974139131","https://openalex.org/W1974471610","https://openalex.org/W1978477577","https://openalex.org/W1979049827","https://openalex.org/W1982759704","https://openalex.org/W1983692314","https://openalex.org/W1984044241","https://openalex.org/W1985475153","https://openalex.org/W1988733774","https://openalex.org/W1990139570","https://openalex.org/W1991888801","https://openalex.org/W1997002078","https://openalex.org/W1997199689","https://openalex.org/W1998751459","https://openalex.org/W1999151538","https://openalex.org/W1999674940","https://openalex.org/W2000937701","https://openalex.org/W2002547755","https://openalex.org/W2004039204","https://openalex.org/W2006606903","https://openalex.org/W2007893172","https://openalex.org/W2008495939","https://openalex.org/W2009204789","https://openalex.org/W2012272386","https://openalex.org/W2012707522","https://openalex.org/W2013567835","https://openalex.org/W2013630484","https://openalex.org/W2018504340","https://openalex.org/W2022890459","https://openalex.org/W2025418692","https://openalex.org/W2027787157","https://openalex.org/W2029905795","https://openalex.org/W2030609925","https://openalex.org/W2034930121","https://openalex.org/W2036622542","https://openalex.org/W2037356904","https://openalex.org/W2037773144","https://openalex.org/W2038457912","https://openalex.org/W2040405360","https://openalex.org/W2040479156","https://openalex.org/W2041033779","https://openalex.org/W2044903986","https://openalex.org/W2045388461","https://openalex.org/W2046845840","https://openalex.org/W2048444860","https://openalex.org/W2049511402","https://openalex.org/W2050029045","https://openalex.org/W2053002347","https://openalex.org/W2054189154","https://openalex.org/W2055449190","https://openalex.org/W2064583380","https://openalex.org/W2070182118","https://openalex.org/W2071306094","https://openalex.org/W2075015873","https://openalex.org/W2077870718","https://openalex.org/W2077978240","https://openalex.org/W2079461103","https://openalex.org/W2081926138","https://openalex.org/W2082675655","https://openalex.org/W2084224847","https://openalex.org/W2085679737","https://openalex.org/W2085692671","https://openalex.org/W2089043560","https://openalex.org/W2091368749","https://openalex.org/W2092749962","https://openalex.org/W2093624389","https://openalex.org/W2094006170","https://openalex.org/W2094108005","https://openalex.org/W2094220461","https://openalex.org/W2094990985","https://openalex.org/W2099318703","https://openalex.org/W2107289916","https://openalex.org/W2109918714","https://openalex.org/W2111023720","https://openalex.org/W2112929560","https://openalex.org/W2114403974","https://openalex.org/W2128156533","https://openalex.org/W2128863256","https://openalex.org/W2139443876","https://openalex.org/W2139802257","https://openalex.org/W2144264198","https://openalex.org/W2145474599","https://openalex.org/W2146408988","https://openalex.org/W2155518779","https://openalex.org/W2158345652","https://openalex.org/W2161051443","https://openalex.org/W2162250373","https://openalex.org/W2162838846","https://openalex.org/W2167925058","https://openalex.org/W2169546138","https://openalex.org/W2169946060","https://openalex.org/W2172297020","https://openalex.org/W2239727806","https://openalex.org/W2325084021","https://openalex.org/W2417149991","https://openalex.org/W2443007980","https://openalex.org/W2770002675","https://openalex.org/W2866991640","https://openalex.org/W3217746387"],"related_works":["https://openalex.org/W7095832874","https://openalex.org/W7153591440","https://openalex.org/W4415279153","https://openalex.org/W96602793","https://openalex.org/W2916175089","https://openalex.org/W4387640012","https://openalex.org/W4392300869","https://openalex.org/W2104752356","https://openalex.org/W2013630484","https://openalex.org/W2971645342"],"abstract_inverted_index":{"Lipids":[0,29],"and":[1,12,39,54,72,75,100,110,137],"lipid":[2,62,82,103,130],"nanoparticles":[3,63,131],"are":[4],"extensively":[5],"employed":[6],"as":[7,42],"oral-delivery":[8],"systems":[9,116],"for":[10,20],"drugs":[11,69,142],"other":[13,120],"active":[14],"ingredients.":[15],"These":[16],"have":[17],"been":[18],"exploited":[19],"many":[21],"features":[22],"in":[23,34,87],"the":[24,35,67,81,114,127,134,138],"field":[25],"of":[26,113,121,129,141],"pharmaceutical":[27],"technology.":[28],"usually":[30],"enhance":[31],"drug":[32,78],"absorption":[33],"gastrointestinal":[36],"tract":[37],"(GIT),":[38],"when":[40,117,143],"formulated":[41],"nanoparticles,":[43],"these":[44],"molecules":[45,79,104],"improve":[46],"mucosal":[47],"adhesion":[48],"due":[49,96],"to":[50,92,97,119,132],"small":[51],"particle":[52],"size":[53],"increasing":[55],"their":[56,98],"GIT":[57],"residence":[58],"time.":[59],"In":[60],"addition,":[61],"may":[64,105],"also":[65],"protect":[66],"loaded":[68],"from":[70,80],"chemical":[71],"enzymatic":[73],"degradation":[74],"gradually":[76],"release":[77,135],"matrix":[83],"into":[84],"blood,":[85],"resulting":[86],"improved":[88],"therapeutic":[89],"profiles":[90],"compared":[91,118],"free":[93],"drug.":[94],"Therefore,":[95],"physiological":[99],"biodegradable":[101],"properties,":[102],"decrease":[106],"adverse":[107],"side":[108],"effects":[109],"chronic":[111],"toxicity":[112],"drug-delivery":[115],"polymeric":[122],"nature.":[123],"This":[124],"paper":[125],"highlights":[126],"importance":[128],"modify":[133],"profile":[136],"pharmacokinetic":[139],"parameters":[140],"administrated":[144],"through":[145],"oral":[146],"route.":[147]},"counts_by_year":[{"year":2026,"cited_by_count":11},{"year":2025,"cited_by_count":15},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":17},{"year":2022,"cited_by_count":30},{"year":2021,"cited_by_count":28},{"year":2020,"cited_by_count":38},{"year":2019,"cited_by_count":25},{"year":2018,"cited_by_count":20},{"year":2017,"cited_by_count":23},{"year":2016,"cited_by_count":26},{"year":2015,"cited_by_count":19},{"year":2014,"cited_by_count":13},{"year":2013,"cited_by_count":11},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2016-06-24T00:00:00"}