{"id":"https://openalex.org/W2012104865","doi":"https://doi.org/10.1371/journal.pone.0017695","title":"CPORT: A Consensus Interface Predictor and Its Performance in Prediction-Driven Docking with HADDOCK","display_name":"CPORT: A Consensus Interface Predictor and Its Performance in Prediction-Driven Docking with HADDOCK","publication_year":2011,"publication_date":"2011-03-25","ids":{"openalex":"https://openalex.org/W2012104865","doi":"https://doi.org/10.1371/journal.pone.0017695","mag":"2012104865","pmid":"https://pubmed.ncbi.nlm.nih.gov/21464987","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3064578"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0017695","doi":"https://doi.org/10.1371/journal.pone.0017695","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0017695","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0017695&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2012104865"],"child_works_count":12,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0017695&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027261495","display_name":"Sjoerd J. de Vries","orcid":"https://orcid.org/0000-0002-7701-3454","observed_orcids":["https://orcid.org/0000-0002-7701-3454"]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Sjoerd J. de Vries","raw_affiliation_strings":["Faculty of Science, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands. a.m.j.j.bonvin@uu.nl","Faculty of Science, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Science, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands. a.m.j.j.bonvin@uu.nl","institution_ids":["https://openalex.org/I193662353"]},{"raw_affiliation_string":"Faculty of Science, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I193662353"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064072429","display_name":"Alexandre M. J. J. Bonvin","orcid":"https://orcid.org/0000-0001-7369-1322","observed_orcids":["https://orcid.org/0000-0001-7369-1322"]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Alexandre M. J. J. Bonvin","raw_affiliation_strings":["Faculty of Science, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Science, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I193662353"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5064072429"],"corresponding_institution_ids":["https://openalex.org/I193662353"],"apc_list":{"value":2382,"currency":"USD","value_usd":2382},"apc_paid":{"value":2382,"currency":"USD","value_usd":2382},"fwci":4.2113,"has_fulltext":true,"cited_by_count":328,"citation_normalized_percentile":{"value":0.95827559,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"6","issue":"3","first_page":"e17695","last_page":"e17695"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.014800000004470348,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.012000000104308128,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/consensus-forecasts","display_name":"consensus forecasts","score":0.7300000190734863},{"id":"https://openalex.org/keywords/haddock","display_name":"haddock","score":0.996999979019165},{"id":"https://openalex.org/keywords/protein-protein-docking","display_name":"protein-protein docking","score":0.6790000200271606},{"id":"https://openalex.org/keywords/blind-docking","display_name":"blind docking","score":0.5669999718666077},{"id":"https://openalex.org/keywords/contact-analysis","display_name":"contact analysis","score":0.6499999761581421},{"id":"https://openalex.org/keywords/web-server","display_name":"web server","score":0.7200000286102295}],"concepts":[{"id":"https://openalex.org/C41685203","wikidata":"https://www.wikidata.org/wiki/Q1974042","display_name":"Docking (animal)","level":2,"score":0.8932891488075256},{"id":"https://openalex.org/C2781442258","wikidata":"https://www.wikidata.org/wiki/Q46310","display_name":"Ab initio","level":2,"score":0.5812524557113647},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5469543933868408},{"id":"https://openalex.org/C44695244","wikidata":"https://www.wikidata.org/wiki/Q7441727","display_name":"Searching the conformational space for docking","level":3,"score":0.48367390036582947},{"id":"https://openalex.org/C18051474","wikidata":"https://www.wikidata.org/wiki/Q899656","display_name":"Protein structure prediction","level":3,"score":0.47236377000808716},{"id":"https://openalex.org/C116887118","wikidata":"https://www.wikidata.org/wiki/Q836685","display_name":"Macromolecular docking","level":3,"score":0.4694618284702301},{"id":"https://openalex.org/C77319485","wikidata":"https://www.wikidata.org/wiki/Q7251520","display_name":"Protein\u2013ligand docking","level":4,"score":0.4370938539505005},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3767886161804199},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.3615459203720093},{"id":"https://openalex.org/C103697762","wikidata":"https://www.wikidata.org/wiki/Q4112105","display_name":"Virtual screening","level":3,"score":0.2830479145050049},{"id":"https://openalex.org/C147597530","wikidata":"https://www.wikidata.org/wiki/Q369472","display_name":"Computational chemistry","level":1,"score":0.26881471276283264},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2613047957420349},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20336279273033142},{"id":"https://openalex.org/C59593255","wikidata":"https://www.wikidata.org/wiki/Q901663","display_name":"Molecular dynamics","level":2,"score":0.20305240154266357},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09997335076332092},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D046912","descriptor_name":"Multiprotein Complexes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":9,"locations":[{"id":"doi:10.1371/journal.pone.0017695","doi":"https://doi.org/10.1371/journal.pone.0017695","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0017695","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0017695&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3064578","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3064578","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmid:21464987","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21464987","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:RePEc:plo:pone00:0017695","doi":null,"is_oa":false,"landing_page_url":"https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017695","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:5c536e9374ea43b7a787b9258156e0cf","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/5c536e9374ea43b7a787b9258156e0cf","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 6, Iss 3, p e17695 (2011)","raw_type":"article"},{"id":"pmh:oai:dspace.library.uu.nl:1874/235166","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/235166","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:figshare.com:article/137960","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/CPORT_A_Consensus_Interface_Predictor_and_Its_Performance_in_Prediction_Driven_Docking_with_HADDOCK/137960","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:uu:oai:dspace.library.uu.nl:1874/235166","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/235166","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS One, 6(3), e17695/1. Public Library of Science","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.795.4790","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.795.4790","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/66/02/pone.0017695.PMC3064578.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0017695","doi":"https://doi.org/10.1371/journal.pone.0017695","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0017695","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0017695&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G175041131","display_name":"Deploying and unifying the NMR e-Infrastructure in System Biology","funder_award_id":"213010","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G3218575804","display_name":"Predicting, modelling and understanding biomolecular interactions in the post-genomic era","funder_award_id":"700.56.442","funder_id":"https://openalex.org/F4320321800","funder_display_name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek"},{"id":"https://openalex.org/G6363223905","display_name":"Pan-European Research infrastructure on High Performance Computing for 21st century Science","funder_award_id":"228398","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G7683943956","display_name":null,"funder_award_id":"HPC-EUROPA2","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321800","display_name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","ror":"https://ror.org/04jsz6e67"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2012104865.pdf","grobid_xml":"https://content.openalex.org/works/W2012104865.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W1548566593","https://openalex.org/W1985481261","https://openalex.org/W1993591356","https://openalex.org/W1995017064","https://openalex.org/W2000383223","https://openalex.org/W2011851849","https://openalex.org/W2014744153","https://openalex.org/W2014957977","https://openalex.org/W2018410079","https://openalex.org/W2027403155","https://openalex.org/W2030728145","https://openalex.org/W2043699100","https://openalex.org/W2046407284","https://openalex.org/W2047468595","https://openalex.org/W2048643046","https://openalex.org/W2053538195","https://openalex.org/W2057813163","https://openalex.org/W2095157453","https://openalex.org/W2104760790","https://openalex.org/W2105438341","https://openalex.org/W2113885150","https://openalex.org/W2118795098","https://openalex.org/W2129454543","https://openalex.org/W2133712572","https://openalex.org/W2133872562","https://openalex.org/W2136525667","https://openalex.org/W2136832587","https://openalex.org/W2141627824","https://openalex.org/W2143881057","https://openalex.org/W2145793759","https://openalex.org/W2148219066","https://openalex.org/W2151311229","https://openalex.org/W2153983456","https://openalex.org/W2154813243","https://openalex.org/W2157991822","https://openalex.org/W2162000798","https://openalex.org/W2162682281","https://openalex.org/W2163561348","https://openalex.org/W2167315103","https://openalex.org/W2488809641","https://openalex.org/W2915344963"],"related_works":["https://openalex.org/W2096734718","https://openalex.org/W2154813243","https://openalex.org/W3119075013","https://openalex.org/W7024003240","https://openalex.org/W4401339769","https://openalex.org/W2064383522","https://openalex.org/W7203589444","https://openalex.org/W2583525420"],"abstract_inverted_index":{"BACKGROUND:":[0],"Macromolecular":[1],"complexes":[2,161,180],"are":[3],"the":[4,8,12,48,120,158,163,189,192,206,220,250,264,272,295],"molecular":[5],"machines":[6],"of":[7,50,63,75,119,160,165,178,191,219],"cell.":[9],"Knowledge":[10],"at":[11,305],"atomic":[13],"level":[14],"is":[15,26,32,57,145,195,236,244,302],"essential":[16],"to":[17,35,71,130,154,294],"understand":[18],"and":[19,28,44,69,114,175,234],"influence":[20],"their":[21,24,80],"function.":[22],"However,":[23],"number":[25],"huge":[27],"a":[29,94,173,182,199],"significant":[30],"fraction":[31],"extremely":[33],"difficult":[34],"study":[36,60,226],"using":[37,232],"classical":[38],"structural":[39,55],"methods":[40],"such":[41],"as":[42],"NMR":[43],"X-ray":[45],"crystallography.":[46],"Therefore,":[47],"importance":[49],"large-scale":[51],"computational":[52,65],"approaches":[53],"in":[54,104,181],"biology":[56],"evident.":[58],"This":[59,243],"combines":[61],"two":[62],"these":[64],"approaches,":[66],"interface":[67,89,102,208,215,276,283],"prediction":[68,90],"docking,":[70,157],"obtain":[72],"atomic-level":[73],"structures":[74],"protein-protein":[76,179],"complexes,":[77],"starting":[78],"from":[79],"unbound":[81],"components.":[82],"METHODOLOGY/PRINCIPAL":[83],"FINDINGS:":[84],"Here":[85],"we":[86],"combine":[87],"six":[88],"web":[91,298],"servers":[92],"into":[93,134],"consensus":[95],"method":[96],"called":[97],"CPORT":[98,110,132,233,301],"(Consensus":[99],"Prediction":[100],"Of":[101],"Residues":[103],"Transient":[105],"complexes).":[106],"We":[107],"show":[108],"that":[109,188,228,274,286],"gives":[111],"more":[112],"stable":[113],"reliable":[115],"predictions":[116,133,209,277],"than":[117],"each":[118],"individual":[121],"predictors":[122],"on":[123,172],"its":[124],"own.":[125],"A":[126,297],"protocol":[127,150],"was":[128,170],"developed":[129],"integrate":[131],"our":[135],"data-driven":[136,255],"docking":[137,149,159,169,221,231,241,248,269,288],"program":[138],"HADDOCK.":[139],"For":[140],"cases":[141],"where":[142],"experimental":[143],"information":[144],"limited,":[146],"this":[147],"prediction-driven":[148,230,247,268,287],"presents":[151],"an":[152],"alternative":[153],"ab":[155,201,239],"initio":[156,202,240],"without":[162],"use":[164],"any":[166,257],"information.":[167],"Prediction-driven":[168],"performed":[171],"large":[174],"diverse":[176],"set":[177],"blind":[183],"manner.":[184],"Our":[185],"results":[186,265],"indicate":[187],"performance":[190],"HADDOCK-CPORT":[193],"combination":[194],"competitive":[196,237],"with":[197,238],"ZDOCK-ZRANK,":[198],"state-of-the-art":[200],"docking/scoring":[203],"combination.":[204],"Finally,":[205,271],"original":[207,275],"could":[210,278],"be":[211,279],"further":[212,280],"improved":[213,281],"by":[214,267,282],"post-prediction":[216,284],"(contact":[217],"analysis":[218],"solutions).":[222],"CONCLUSIONS/SIGNIFICANCE:":[223],"The":[224],"current":[225],"shows":[227],"blind,":[229],"HADDOCK":[235],"methods.":[242],"encouraging":[245],"since":[246],"represents":[249],"absolute":[251],"bottom":[252],"line":[253],"for":[254,300],"docking:":[256],"additional":[258],"biological":[259],"knowledge":[260],"will":[261],"greatly":[262],"improve":[263],"obtained":[266],"alone.":[270],"fact":[273],"suggests":[285],"has":[289],"not":[290],"yet":[291],"been":[292],"pushed":[293],"limit.":[296],"server":[299],"freely":[303],"available":[304],"http://haddock.chem.uu.nl/services/CPORT.":[306]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":28},{"year":2023,"cited_by_count":34},{"year":2022,"cited_by_count":34},{"year":2021,"cited_by_count":43},{"year":2020,"cited_by_count":36},{"year":2019,"cited_by_count":24},{"year":2018,"cited_by_count":19},{"year":2017,"cited_by_count":14},{"year":2016,"cited_by_count":18},{"year":2015,"cited_by_count":19},{"year":2014,"cited_by_count":15},{"year":2013,"cited_by_count":11},{"year":2012,"cited_by_count":11}],"updated_date":"2026-11-15T12:55:33.944570","created_date":"2016-06-24T00:00:00"}