{"id":"https://openalex.org/W2012078324","doi":"https://doi.org/10.1074/jbc.274.26.18428","title":"Transcriptional Induction of the Urokinase Receptor Gene by a Constitutively Active Src","display_name":"Transcriptional Induction of the Urokinase Receptor Gene by a Constitutively Active Src","publication_year":1999,"publication_date":"1999-06-01","ids":{"openalex":"https://openalex.org/W2012078324","doi":"https://doi.org/10.1074/jbc.274.26.18428","mag":"2012078324","pmid":"https://pubmed.ncbi.nlm.nih.gov/10373450"},"language":"en","primary_location":{"id":"doi:10.1074/jbc.274.26.18428","doi":"https://doi.org/10.1074/jbc.274.26.18428","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.274.26.18428","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1074/jbc.274.26.18428","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025744948","display_name":"Heike Allgayer","orcid":"https://orcid.org/0000-0003-2192-5101","observed_orcids":["https://orcid.org/0000-0003-2192-5101"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heike Allgayer","raw_affiliation_strings":["Department of Cancer Biology, M.D. Anderson Cancer Center, Houston, Texas 77030, USA","From the Department of Cancer Biology, M.D. Anderson Cancer Center, Houston, Texas 77030"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cancer Biology, M.D. Anderson Cancer Center, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"From the Department of Cancer Biology, M.D. Anderson Cancer Center, Houston, Texas 77030","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100453950","display_name":"Heng Wang","orcid":"https://orcid.org/0000-0002-1727-9226","observed_orcids":["https://orcid.org/0000-0002-1727-9226","https://orcid.org/0000-0003-4229-8426"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heng Wang","raw_affiliation_strings":["From the Department of Cancer Biology, M.D. Anderson Cancer Center, Houston, Texas 77030"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cancer Biology, M.D. Anderson Cancer Center, Houston, Texas 77030","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111690153","display_name":"Gary E. Gallick","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gary E. Gallick","raw_affiliation_strings":["From the Department of Cancer Biology, M.D. Anderson Cancer Center, Houston, Texas 77030"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cancer Biology, M.D. Anderson Cancer Center, Houston, Texas 77030","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064905746","display_name":"Andrea Crabtree","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrea Crabtree","raw_affiliation_strings":["From the Department of Cancer Biology, M.D. Anderson Cancer Center, Houston, Texas 77030"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cancer Biology, M.D. Anderson Cancer Center, Houston, Texas 77030","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065530824","display_name":"Andrew Paul Mazar","orcid":"https://orcid.org/0009-0000-3681-6704","observed_orcids":["https://orcid.org/0009-0000-3681-6704"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew Mazar","raw_affiliation_strings":["From the Department of Cancer Biology, M.D. Anderson Cancer Center, Houston, Texas 77030"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cancer Biology, M.D. Anderson Cancer Center, Houston, Texas 77030","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073679998","display_name":"Terence R. Jones","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Terence Jones","raw_affiliation_strings":["From the Department of Cancer Biology, M.D. Anderson Cancer Center, Houston, Texas 77030"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cancer Biology, M.D. Anderson Cancer Center, Houston, Texas 77030","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109919617","display_name":"Alan J. Kraker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alan J. Kraker","raw_affiliation_strings":["From the Department of Cancer Biology, M.D. Anderson Cancer Center, Houston, Texas 77030"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cancer Biology, M.D. Anderson Cancer Center, Houston, Texas 77030","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084442354","display_name":"Douglas D. Boyd","orcid":"https://orcid.org/0000-0002-1380-402X","observed_orcids":["https://orcid.org/0000-0002-1380-402X"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Douglas D. Boyd","raw_affiliation_strings":["From the Department of Cancer Biology, M.D. Anderson Cancer Center, Houston, Texas 77030"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cancer Biology, M.D. Anderson Cancer Center, Houston, Texas 77030","institution_ids":["https://openalex.org/I1343551460"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5084442354"],"corresponding_institution_ids":["https://openalex.org/I1343551460"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":1.8365,"has_fulltext":false,"cited_by_count":72,"citation_normalized_percentile":{"value":0.85796074,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"274","issue":"26","first_page":"18428","last_page":"18437"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11501","display_name":"TGF-\u03b2 signaling in diseases","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/urokinase-receptor","display_name":"urokinase receptor","score":0.9800000190734863},{"id":"https://openalex.org/keywords/src-kinase","display_name":"Src kinase","score":0.5559999942779541},{"id":"https://openalex.org/keywords/colon-cancer","display_name":"colon cancer","score":0.7239999771118164},{"id":"https://openalex.org/keywords/sp1-binding","display_name":"Sp1 binding","score":0.7490000128746033},{"id":"https://openalex.org/keywords/promoter-cis-acting-elements","display_name":"promoter cis-acting elements","score":0.7519999742507935},{"id":"https://openalex.org/keywords/laminin-degradation","display_name":"laminin degradation","score":0.953000009059906},{"id":"https://openalex.org/keywords/sw480-cells","display_name":"SW480 cells","score":0.8920000195503235},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.5350000262260437}],"concepts":[{"id":"https://openalex.org/C56219504","wikidata":"https://www.wikidata.org/wiki/Q7900869","display_name":"Urokinase receptor","level":3,"score":0.7311850786209106},{"id":"https://openalex.org/C108636557","wikidata":"https://www.wikidata.org/wiki/Q21109354","display_name":"Proto-oncogene tyrosine-protein kinase Src","level":3,"score":0.6335455179214478},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.49917006492614746},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.46468380093574524},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.44814276695251465},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4004260301589966},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3476409316062927},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.326540470123291},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.27548250555992126}],"mesh":[{"descriptor_ui":"D004591","descriptor_name":"Electrophoresis, Polyacrylamide Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011956","descriptor_name":"Receptors, Cell Surface","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011956","descriptor_name":"Receptors, Cell Surface","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014568","descriptor_name":"Urokinase-Type Plasminogen Activator","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016329","descriptor_name":"Sp1 Transcription Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018909","descriptor_name":"src Homology Domains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055293","descriptor_name":"Receptors, Urokinase Plasminogen Activator","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1074/jbc.274.26.18428","doi":"https://doi.org/10.1074/jbc.274.26.18428","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.274.26.18428","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},{"id":"pmid:10373450","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10373450","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biological chemistry","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1074/jbc.274.26.18428","doi":"https://doi.org/10.1074/jbc.274.26.18428","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.274.26.18428","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G203231466","display_name":null,"funder_award_id":"P01 DE11906","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G7914991926","display_name":"Regulation of type IV collagenase expression","funder_award_id":"R01DE010845","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G8167899804","display_name":"Regulation of urokinase receptor expression in colon cancer","funder_award_id":"R01CA058311","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337365","display_name":"National Institute of Dental and Craniofacial Research","ror":"https://ror.org/004a2wv92"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":54,"referenced_works":["https://openalex.org/W45293395","https://openalex.org/W146261343","https://openalex.org/W1275325292","https://openalex.org/W1481724645","https://openalex.org/W1487780734","https://openalex.org/W1497832606","https://openalex.org/W1497917975","https://openalex.org/W1534435601","https://openalex.org/W1540038532","https://openalex.org/W1543536169","https://openalex.org/W1550325341","https://openalex.org/W1557341375","https://openalex.org/W1583835478","https://openalex.org/W1598321878","https://openalex.org/W1604744894","https://openalex.org/W1670322156","https://openalex.org/W1672973700","https://openalex.org/W1792229897","https://openalex.org/W1971241686","https://openalex.org/W1978165300","https://openalex.org/W1978847194","https://openalex.org/W1997526503","https://openalex.org/W1999899623","https://openalex.org/W2003593894","https://openalex.org/W2005847772","https://openalex.org/W2008422280","https://openalex.org/W2010632289","https://openalex.org/W2013687281","https://openalex.org/W2014906721","https://openalex.org/W2016450706","https://openalex.org/W2020537787","https://openalex.org/W2030565228","https://openalex.org/W2034499790","https://openalex.org/W2042155824","https://openalex.org/W2049631846","https://openalex.org/W2058849071","https://openalex.org/W2080258889","https://openalex.org/W2100404293","https://openalex.org/W2110274253","https://openalex.org/W2126888026","https://openalex.org/W2128647783","https://openalex.org/W2131243830","https://openalex.org/W2132764202","https://openalex.org/W2135092755","https://openalex.org/W2144955716","https://openalex.org/W2149585395","https://openalex.org/W2154671319","https://openalex.org/W2167401403","https://openalex.org/W2284365973","https://openalex.org/W2286875504","https://openalex.org/W2316299830","https://openalex.org/W2403510858","https://openalex.org/W2403720363","https://openalex.org/W4324263428"],"related_works":["https://openalex.org/W2156782693","https://openalex.org/W2126888026","https://openalex.org/W1583040017","https://openalex.org/W2005847772","https://openalex.org/W2171883866","https://openalex.org/W2317224850","https://openalex.org/W2009633597","https://openalex.org/W2034499790","https://openalex.org/W2007026034","https://openalex.org/W2025637687"],"abstract_inverted_index":{"Since":[0],"c-src":[1],"overexpression":[2],"increases":[3],"colonic":[4],"cell":[5],"invasiveness":[6],"and":[7,12,39,45,70,87,176],"because":[8],"both":[9],"Src":[10,34,62,71,182,196],"activity":[11,120],"urokinase":[13,36,66,83,100,106,168,189],"receptor":[14,37,67,84,101,107,169,190],"protein":[15,63,85,170],"are":[16],"elevated":[17],"in":[18,104,141,172],"invasive":[19],"colon":[20,49,174,179],"cancers,":[21],"the":[22,75,99,114,119,133,138,142,150],"present":[23],"study":[24],"was":[25,129,145],"undertaken:":[26],"1)":[27],"to":[28,41,157],"determine":[29],"if":[30],"a":[31,59,79,122],"constitutively":[32,60],"active":[33,61],"regulates":[35],"expression":[38,55,69,192],"2)":[40],"identify":[42],"required":[43],"cis-elements":[44],"trans-acting":[46],"factors.":[47],"SW480":[48,164],"cancer":[50],"cells":[51],"transfected":[52],"with":[53,78,161,181],"an":[54,95],"plasmid":[56],"(c-srcY527F)":[57],"encoding":[58],"manifested":[64],"increased":[65,154,199],"gene":[68,191],"activity.":[72,184],"Treatment":[73],"of":[74,98,121],"src":[76,151],"transfectants":[77,152],"Src-inhibitor":[80],"(PD173955)":[81],"reduced":[82],"levels":[86],"laminin":[88],"degradation.":[89],"Inasmuch":[90],"as":[91],"we":[92,109],"recently":[93],"implicated":[94],"upstream":[96],"region":[97,128,144,158],"promoter":[102,135],"(-152/-135)":[103],"constitutive":[105],"expression,":[108],"determined":[110],"its":[111],"role":[112],"for":[113],"induction":[115],"by":[116,126,131,195],"src.":[117],"Whereas":[118],"CAT":[123],"reporter":[124],"driven":[125],"this":[127],"stimulated":[130],"c-srcY527F,":[132],"u-PAR":[134],"mutated":[136],"at":[137],"Sp1-binding":[139],"motif":[140],"-152/-135":[143,159],"not.":[146],"Nuclear":[147],"extracts":[148],"from":[149,163],"demonstrated":[153],"Sp1":[155,200],"binding":[156],"compared":[160],"those":[162],"cells.":[165],"Finally,":[166],"endogenous":[167],"amounts":[171],"10":[173],"cancers":[175],"corresponding":[177],"normal":[178],"correlated":[180],"specific":[183],"These":[185],"data":[186],"suggest":[187],"that":[188],"is":[193],"regulated":[194],"partly":[197],"via":[198],"binding.":[201]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}
