{"id":"https://openalex.org/W2011997395","doi":"https://doi.org/10.1006/biol.1998.0130","title":"Clearance of Murine Leukaemia Virus from Monoclonal Antibody Solution by a Hydrophilic PVDF Microporous Membrane Filter","display_name":"Clearance of Murine Leukaemia Virus from Monoclonal Antibody Solution by a Hydrophilic PVDF Microporous Membrane Filter","publication_year":1998,"publication_date":"1998-06-01","ids":{"openalex":"https://openalex.org/W2011997395","doi":"https://doi.org/10.1006/biol.1998.0130","mag":"2011997395","pmid":"https://pubmed.ncbi.nlm.nih.gov/9811524"},"language":"en","primary_location":{"id":"doi:10.1006/biol.1998.0130","doi":"https://doi.org/10.1006/biol.1998.0130","is_oa":false,"landing_page_url":"https://doi.org/10.1006/biol.1998.0130","pdf_url":null,"source":{"id":"https://openalex.org/S110177920","display_name":"Biologicals","issn_l":"1045-1056","issn":["1045-1056","1095-8320"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biologicals","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000454881","display_name":"Hazel Aranha\u2010Creado","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I103017756","display_name":"Pall Corporation (United States)","ror":"https://ror.org/057jpj338","country_code":"US","type":"company","lineage":["https://openalex.org/I103017756"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hazel Aranha-Creado","raw_affiliation_strings":["Scientific and Laboratory Services Dept., Pall Corporation, Port Washington, NY 11050, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Scientific and Laboratory Services Dept., Pall Corporation, Port Washington, NY 11050, USA","institution_ids":["https://openalex.org/I103017756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105123833","display_name":"John J. Peterson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210152047","display_name":"PDL BioPharma (United States)","ror":"https://ror.org/03ya6pd97","country_code":"US","type":"company","lineage":["https://openalex.org/I4210152047"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John Peterson","raw_affiliation_strings":["Protein Design Laboratories, Plymouth, MN 55447, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Protein Design Laboratories, Plymouth, MN 55447, U.S.A","institution_ids":["https://openalex.org/I4210152047"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113691727","display_name":"Ping Yu. Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210152047","display_name":"PDL BioPharma (United States)","ror":"https://ror.org/03ya6pd97","country_code":"US","type":"company","lineage":["https://openalex.org/I4210152047"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ping Y. Huang","raw_affiliation_strings":["Protein Design Laboratories, Plymouth, MN 55447, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Protein Design Laboratories, Plymouth, MN 55447, U.S.A","institution_ids":["https://openalex.org/I4210152047"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.0969,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.31532767,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"26","issue":"2","first_page":"167","last_page":"172"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11124","display_name":"Protein purification and stability","score":0.9520999789237976,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11124","display_name":"Protein purification and stability","score":0.9520999789237976,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.025800000876188278,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.005799999926239252,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/murine-leukemia-virus","display_name":"murine leukemia virus","score":0.9869999885559082},{"id":"https://openalex.org/keywords/monoclonal-antibody-purification","display_name":"monoclonal antibody purification","score":0.6840000152587891},{"id":"https://openalex.org/keywords/polyvinylidene-fluoride-membranes","display_name":"PVDF membranes","score":0.8309999704360962},{"id":"https://openalex.org/keywords/viral-clearance","display_name":"viral clearance","score":0.5329999923706055},{"id":"https://openalex.org/keywords/immortalized-cell-lines","display_name":"immortalized cell lines","score":0.5759999752044678},{"id":"https://openalex.org/keywords/monoclonal-immunoglobulin-g","display_name":"monoclonal immunoglobulin G","score":0.7870000004768372}],"concepts":[{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.8437525629997253},{"id":"https://openalex.org/C2776254723","wikidata":"https://www.wikidata.org/wiki/Q146393","display_name":"Polyvinylidene fluoride","level":3,"score":0.6456528902053833},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.6022518873214722},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.4806453287601471},{"id":"https://openalex.org/C86381522","wikidata":"https://www.wikidata.org/wiki/Q2752988","display_name":"Microporous material","level":2,"score":0.474201500415802},{"id":"https://openalex.org/C128489963","wikidata":"https://www.wikidata.org/wiki/Q1187724","display_name":"Filtration (mathematics)","level":2,"score":0.47048524022102356},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.45688846707344055},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.45260727405548096},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.38168829679489136},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.38027632236480713},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2676156163215637},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.15077537298202515},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11209404468536377},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D001681","descriptor_name":"Biological Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004340","descriptor_name":"Drug Contamination","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D005069","descriptor_name":"Evaluation Studies as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005465","descriptor_name":"Fluorocarbon Polymers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006825","descriptor_name":"Hybridomas","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008851","descriptor_name":"Micropore Filters","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009052","descriptor_name":"Leukemia Virus, Murine","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D011145","descriptor_name":"Polyvinyls","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012449","descriptor_name":"Safety","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012996","descriptor_name":"Solutions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014462","descriptor_name":"Ultrafiltration","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1006/biol.1998.0130","doi":"https://doi.org/10.1006/biol.1998.0130","is_oa":false,"landing_page_url":"https://doi.org/10.1006/biol.1998.0130","pdf_url":null,"source":{"id":"https://openalex.org/S110177920","display_name":"Biologicals","issn_l":"1045-1056","issn":["1045-1056","1095-8320"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biologicals","raw_type":"journal-article"},{"id":"pmid:9811524","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9811524","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biologicals : journal of the International Association of Biological Standardization","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2111753957","https://openalex.org/W2155885371","https://openalex.org/W2090323079","https://openalex.org/W8414844","https://openalex.org/W93904316","https://openalex.org/W1836489886","https://openalex.org/W2089626975","https://openalex.org/W4391993639","https://openalex.org/W4414800888","https://openalex.org/W7126251869"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}