{"id":"https://openalex.org/W2011967604","doi":"https://doi.org/10.1530/acta.0.062s222","title":"RADIOIMMUNOASSAY WITH ANTIBODY-COATED DISCS AND TUBES","display_name":"RADIOIMMUNOASSAY WITH ANTIBODY-COATED DISCS AND TUBES","publication_year":1969,"publication_date":"1969-12-01","ids":{"openalex":"https://openalex.org/W2011967604","doi":"https://doi.org/10.1530/acta.0.062s222","mag":"2011967604","pmid":"https://pubmed.ncbi.nlm.nih.gov/5308646"},"language":"en","primary_location":{"id":"doi:10.1530/acta.0.062s222","doi":"https://doi.org/10.1530/acta.0.062s222","is_oa":false,"landing_page_url":"https://doi.org/10.1530/acta.0.062s222","pdf_url":null,"source":{"id":"https://openalex.org/S4210218062","display_name":"European Journal of Endocrinology","issn_l":"0804-4643","issn":["0804-4643","1479-683X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Endocrinologica","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111815154","display_name":"K. J. Catt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"K. J. Catt","raw_affiliation_strings":["Department of Medicine, Monash University, Prince Henry\u2019s Hospital, Melbourne, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Monash University, Prince Henry\u2019s Hospital, Melbourne, Australia","institution_ids":["https://openalex.org/I56590836"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5111815154"],"corresponding_institution_ids":["https://openalex.org/I56590836"],"apc_list":{"value":3798,"currency":"EUR","value_usd":4292},"apc_paid":null,"fwci":0.8758,"has_fulltext":false,"cited_by_count":35,"citation_normalized_percentile":{"value":0.65868304,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"62","issue":"1_Suppl","first_page":"S222","last_page":"S246"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.3131999969482422,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12867","display_name":"Advanced Biosensing Techniques and Applications","score":0.3131999969482422,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.13009999692440033,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":0.11959999799728394,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radioimmunoassay","display_name":"radioimmunoassay","score":0.875},{"id":"https://openalex.org/keywords/solid-phase-immunoassay","display_name":"solid-phase immunoassay","score":0.8309999704360962},{"id":"https://openalex.org/keywords/peptide-hormones","display_name":"peptide hormones","score":0.8489999771118164},{"id":"https://openalex.org/keywords/gonadotropins","display_name":"gonadotropins","score":0.7580000162124634},{"id":"https://openalex.org/keywords/human-growth-hormone","display_name":"human growth hormone","score":0.7950000166893005},{"id":"https://openalex.org/keywords/human-chorionic-gonadotropin","display_name":"human chorionic gonadotropin","score":0.8709999918937683},{"id":"https://openalex.org/keywords/luteinizing-hormone","display_name":"luteinizing hormone","score":0.8899999856948853},{"id":"https://openalex.org/keywords/prolactin","display_name":"prolactin","score":0.9210000038146973},{"id":"https://openalex.org/keywords/estrogen-secretion","display_name":"estrogen secretion","score":0.7099999785423279},{"id":"https://openalex.org/keywords/lh-release","display_name":"LH release","score":0.8870000243186951},{"id":"https://openalex.org/keywords/plasma-hormone-measurement","display_name":"plasma hormone measurement","score":0.7369999885559082},{"id":"https://openalex.org/keywords/ligand-binding","display_name":"ligand binding","score":0.4819999933242798}],"concepts":[{"id":"https://openalex.org/C176685330","wikidata":"https://www.wikidata.org/wiki/Q857638","display_name":"Radioimmunoassay","level":2,"score":0.9651098251342773},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6996679902076721},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5663487911224365},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5067105889320374},{"id":"https://openalex.org/C2779064019","wikidata":"https://www.wikidata.org/wiki/Q66590068","display_name":"Prolactin","level":3,"score":0.49148833751678467},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.4872225821018219},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.45917820930480957},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3669469952583313},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.36098167300224304},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22658735513687134},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19181746244430542},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.15284943580627441},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1278306245803833}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000906","descriptor_name":"Antibodies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000941","descriptor_name":"Antigens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004967","descriptor_name":"Estrogens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006062","descriptor_name":"Gonadotropins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D006063","descriptor_name":"Chorionic Gonadotropin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007986","descriptor_name":"Luteinizing Hormone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011863","descriptor_name":"Radioimmunoassay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1530/acta.0.062s222","doi":"https://doi.org/10.1530/acta.0.062s222","is_oa":false,"landing_page_url":"https://doi.org/10.1530/acta.0.062s222","pdf_url":null,"source":{"id":"https://openalex.org/S4210218062","display_name":"European Journal of Endocrinology","issn_l":"0804-4643","issn":["0804-4643","1479-683X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta Endocrinologica","raw_type":"journal-article"},{"id":"pmid:5308646","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5308646","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta endocrinologica. Supplementum","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1974109098","https://openalex.org/W2014870763","https://openalex.org/W2322333218","https://openalex.org/W2050710094","https://openalex.org/W2042827832","https://openalex.org/W2014728001","https://openalex.org/W2913852280","https://openalex.org/W1981173453","https://openalex.org/W2080707322","https://openalex.org/W4249323132"],"abstract_inverted_index":{"ABSTRACT":[0],"The":[1,35,56,149],"measurement":[2,104],"of":[3,14,22,67,77,105,121,127,160,166],"polypeptide":[4],"hormones":[5,129],"by":[6,11,30],"radioimmunoassay":[7,37,72],"has":[8,73],"been":[9,54,100],"facilitated":[10],"the":[12,20,44,75,84,103,119,125,138,164],"introduction":[13],"solid-phase":[15,36],"antibody":[16,68],"preparations":[17],"which":[18,83],"permit":[19],"separation":[21],"bound":[23],"and":[24,46,51,113,132,137,144,156,158,172],"free":[25],"tracer":[26],"to":[27,163],"be":[28],"performed":[29,87],"a":[31],"rapid":[32,155],"washing":[33],"step.":[34],"technique":[38],"originally":[39],"employed":[40],"substituted":[41],"powders":[42],"as":[43,169],"solid-phase,":[45],"more":[47],"recently,":[48],"antibody-coated":[49],"discs":[50],"tubes":[52,61,91],"have":[53,99],"used.":[55],"observation":[57],"that":[58],"standard":[59],"plastic":[60,89],"would":[62],"adsorb":[63],"an":[64,78],"appropriate":[65],"quantity":[66],"for":[69,102,124],"use":[70,120],"in":[71,82,88,130],"allowed":[74],"development":[76],"extremely":[79],"simple":[80],"method,":[81],"assay":[85,151,165],"is":[86,147,153,159],"counting":[90],"coated":[92],"with":[93,175],"specific":[94,176],"antibody.":[95],"Antibody-coated":[96],"tube":[97],"assays":[98,123],"established":[101],"HGH,":[106],"HCS,":[107],"HLH,":[108],"ovine":[109,111,133],"LH,":[110],"prolactin":[112],"other":[114,173],"hormones.":[115],"Recent":[116],"observations":[117],"on":[118],"coated-tube":[122,150],"estimation":[126],"gonadotrophic":[128],"human":[131],"plasma":[134],"are":[135],"described,":[136],"temporal":[139],"relationship":[140],"between":[141],"oestrogen":[142],"secretion":[143],"LH":[145],"release":[146],"presented.":[148],"procedure":[152],"simple,":[154],"reliable,":[157],"general":[161],"application":[162],"ligands":[167],"such":[168],"antigens,":[170],"steroids":[171],"molecules":[174],"binding":[177],"proteins.":[178]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}