{"id":"https://openalex.org/W2011949118","doi":"https://doi.org/10.1016/s0039-6060(99)70291-6","title":"Pancreatic cancer cells can evade immune surveillance via nonfunctional Fas (APO-1/CD95) receptors and aberrant expression of functional Fas ligand","display_name":"Pancreatic cancer cells can evade immune surveillance via nonfunctional Fas (APO-1/CD95) receptors and aberrant expression of functional Fas ligand","publication_year":1999,"publication_date":"1999-01-01","ids":{"openalex":"https://openalex.org/W2011949118","doi":"https://doi.org/10.1016/s0039-6060(99)70291-6","mag":"2011949118","pmid":"https://pubmed.ncbi.nlm.nih.gov/9889801"},"language":"en","primary_location":{"id":"doi:10.1016/s0039-6060(99)70291-6","doi":"https://doi.org/10.1016/s0039-6060(99)70291-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0039-6060(99)70291-6","pdf_url":null,"source":{"id":"https://openalex.org/S4210173306","display_name":"Surgery","issn_l":"0039-6060","issn":["0039-6060","1532-7361"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgery","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061893056","display_name":"Wolfram von Bernstorff","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Wolfram v. Bernstorff","raw_affiliation_strings":["Boston, Mass From the Laboratory of Biologic Cancer Therapy, Division of Surgical Oncology, Department of Surgery, and the Tissue Typing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass a Current address: Department of Otolaryngology, Boston University School of Medicine, Cancer Research Center, Boston, Mass. b Current address: Abteilung f\u00fcr Allgemeinchirurgie, Chirurgische Klinik, Universit\u00e4ts-Krankenhaus Hamburg-Eppendorf, Hamburg, Germany","Boston University, Boston, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston, Mass From the Laboratory of Biologic Cancer Therapy, Division of Surgical Oncology, Department of Surgery, and the Tissue Typing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass a Current address: Department of Otolaryngology, Boston University School of Medicine, Cancer Research Center, Boston, Mass. b Current address: Abteilung f\u00fcr Allgemeinchirurgie, Chirurgische Klinik, Universit\u00e4ts-Krankenhaus Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Boston University, Boston, United States","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010885224","display_name":"Remco A. Spanjaard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Remco A. Spanjaard","raw_affiliation_strings":["Boston, Mass From the Laboratory of Biologic Cancer Therapy, Division of Surgical Oncology, Department of Surgery, and the Tissue Typing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass a Current address: Department of Otolaryngology, Boston University School of Medicine, Cancer Research Center, Boston, Mass. b Current address: Abteilung f\u00fcr Allgemeinchirurgie, Chirurgische Klinik, Universit\u00e4ts-Krankenhaus Hamburg-Eppendorf, Hamburg, Germany","Boston University, Boston, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston, Mass From the Laboratory of Biologic Cancer Therapy, Division of Surgical Oncology, Department of Surgery, and the Tissue Typing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass a Current address: Department of Otolaryngology, Boston University School of Medicine, Cancer Research Center, Boston, Mass. b Current address: Abteilung f\u00fcr Allgemeinchirurgie, Chirurgische Klinik, Universit\u00e4ts-Krankenhaus Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Boston University, Boston, United States","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Allen K. Chan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Allen K. Chan","raw_affiliation_strings":["Boston, Mass From the Laboratory of Biologic Cancer Therapy, Division of Surgical Oncology, Department of Surgery, and the Tissue Typing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass a Current address: Department of Otolaryngology, Boston University School of Medicine, Cancer Research Center, Boston, Mass. b Current address: Abteilung f\u00fcr Allgemeinchirurgie, Chirurgische Klinik, Universit\u00e4ts-Krankenhaus Hamburg-Eppendorf, Hamburg, Germany","Boston University, Boston, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston, Mass From the Laboratory of Biologic Cancer Therapy, Division of Surgical Oncology, Department of Surgery, and the Tissue Typing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass a Current address: Department of Otolaryngology, Boston University School of Medicine, Cancer Research Center, Boston, Mass. b Current address: Abteilung f\u00fcr Allgemeinchirurgie, Chirurgische Klinik, Universit\u00e4ts-Krankenhaus Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Boston University, Boston, United States","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072540456","display_name":"Diane C. Lockhart","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Diane C. Lockhart","raw_affiliation_strings":["Boston, Mass From the Laboratory of Biologic Cancer Therapy, Division of Surgical Oncology, Department of Surgery, and the Tissue Typing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass a Current address: Department of Otolaryngology, Boston University School of Medicine, Cancer Research Center, Boston, Mass. b Current address: Abteilung f\u00fcr Allgemeinchirurgie, Chirurgische Klinik, Universit\u00e4ts-Krankenhaus Hamburg-Eppendorf, Hamburg, Germany","Boston University, Boston, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston, Mass From the Laboratory of Biologic Cancer Therapy, Division of Surgical Oncology, Department of Surgery, and the Tissue Typing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass a Current address: Department of Otolaryngology, Boston University School of Medicine, Cancer Research Center, Boston, Mass. b Current address: Abteilung f\u00fcr Allgemeinchirurgie, Chirurgische Klinik, Universit\u00e4ts-Krankenhaus Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Boston University, Boston, United States","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070068637","display_name":"Noriaki Sadanaga","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Noriaki Sadanaga","raw_affiliation_strings":["Boston, Mass From the Laboratory of Biologic Cancer Therapy, Division of Surgical Oncology, Department of Surgery, and the Tissue Typing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass a Current address: Department of Otolaryngology, Boston University School of Medicine, Cancer Research Center, Boston, Mass. b Current address: Abteilung f\u00fcr Allgemeinchirurgie, Chirurgische Klinik, Universit\u00e4ts-Krankenhaus Hamburg-Eppendorf, Hamburg, Germany","Boston University, Boston, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston, Mass From the Laboratory of Biologic Cancer Therapy, Division of Surgical Oncology, Department of Surgery, and the Tissue Typing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass a Current address: Department of Otolaryngology, Boston University School of Medicine, Cancer Research Center, Boston, Mass. b Current address: Abteilung f\u00fcr Allgemeinchirurgie, Chirurgische Klinik, Universit\u00e4ts-Krankenhaus Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Boston University, Boston, United States","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104440826","display_name":"Isabelle G. Wood","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Isabelle Wood","raw_affiliation_strings":["Boston, Mass From the Laboratory of Biologic Cancer Therapy, Division of Surgical Oncology, Department of Surgery, and the Tissue Typing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass a Current address: Department of Otolaryngology, Boston University School of Medicine, Cancer Research Center, Boston, Mass. b Current address: Abteilung f\u00fcr Allgemeinchirurgie, Chirurgische Klinik, Universit\u00e4ts-Krankenhaus Hamburg-Eppendorf, Hamburg, Germany","Boston University, Boston, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston, Mass From the Laboratory of Biologic Cancer Therapy, Division of Surgical Oncology, Department of Surgery, and the Tissue Typing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass a Current address: Department of Otolaryngology, Boston University School of Medicine, Cancer Research Center, Boston, Mass. b Current address: Abteilung f\u00fcr Allgemeinchirurgie, Chirurgische Klinik, Universit\u00e4ts-Krankenhaus Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Boston University, Boston, United States","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059284457","display_name":"Matthias Peiper","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Matthias Peiper","raw_affiliation_strings":["Boston, Mass From the Laboratory of Biologic Cancer Therapy, Division of Surgical Oncology, Department of Surgery, and the Tissue Typing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass a Current address: Department of Otolaryngology, Boston University School of Medicine, Cancer Research Center, Boston, Mass. b Current address: Abteilung f\u00fcr Allgemeinchirurgie, Chirurgische Klinik, Universit\u00e4ts-Krankenhaus Hamburg-Eppendorf, Hamburg, Germany","Boston University, Boston, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston, Mass From the Laboratory of Biologic Cancer Therapy, Division of Surgical Oncology, Department of Surgery, and the Tissue Typing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass a Current address: Department of Otolaryngology, Boston University School of Medicine, Cancer Research Center, Boston, Mass. b Current address: Abteilung f\u00fcr Allgemeinchirurgie, Chirurgische Klinik, Universit\u00e4ts-Krankenhaus Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Boston University, Boston, United States","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062157417","display_name":"Peter S. Goedegebuure","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Peter S. Goedegebuure","raw_affiliation_strings":["Boston, Mass From the Laboratory of Biologic Cancer Therapy, Division of Surgical Oncology, Department of Surgery, and the Tissue Typing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass a Current address: Department of Otolaryngology, Boston University School of Medicine, Cancer Research Center, Boston, Mass. b Current address: Abteilung f\u00fcr Allgemeinchirurgie, Chirurgische Klinik, Universit\u00e4ts-Krankenhaus Hamburg-Eppendorf, Hamburg, Germany","Boston University, Boston, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston, Mass From the Laboratory of Biologic Cancer Therapy, Division of Surgical Oncology, Department of Surgery, and the Tissue Typing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass a Current address: Department of Otolaryngology, Boston University School of Medicine, Cancer Research Center, Boston, Mass. b Current address: Abteilung f\u00fcr Allgemeinchirurgie, Chirurgische Klinik, Universit\u00e4ts-Krankenhaus Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Boston University, Boston, United States","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032371242","display_name":"Timothy J. Eberlein","orcid":"https://orcid.org/0009-0008-7076-2357","observed_orcids":["https://orcid.org/0009-0008-7076-2357"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Timothy J. Eberlein","raw_affiliation_strings":["Boston, Mass From the Laboratory of Biologic Cancer Therapy, Division of Surgical Oncology, Department of Surgery, and the Tissue Typing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass a Current address: Department of Otolaryngology, Boston University School of Medicine, Cancer Research Center, Boston, Mass. b Current address: Abteilung f\u00fcr Allgemeinchirurgie, Chirurgische Klinik, Universit\u00e4ts-Krankenhaus Hamburg-Eppendorf, Hamburg, Germany","Boston University, Boston, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Boston, Mass From the Laboratory of Biologic Cancer Therapy, Division of Surgical Oncology, Department of Surgery, and the Tissue Typing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass a Current address: Department of Otolaryngology, Boston University School of Medicine, Cancer Research Center, Boston, Mass. b Current address: Abteilung f\u00fcr Allgemeinchirurgie, Chirurgische Klinik, Universit\u00e4ts-Krankenhaus Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Boston University, Boston, United States","institution_ids":["https://openalex.org/I111088046"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4130,"currency":"USD","value_usd":4130},"apc_paid":null,"fwci":2.9313,"has_fulltext":false,"cited_by_count":102,"citation_normalized_percentile":{"value":0.91521428,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"125","issue":"1","first_page":"0073","last_page":"0084"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.9146000146865845,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.9146000146865845,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.04780000075697899,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.0034000000450760126,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pancreatic-cancer","display_name":"pancreatic cancer","score":0.9980000257492065},{"id":"https://openalex.org/keywords/fas","display_name":"Fas","score":0.8799999952316284},{"id":"https://openalex.org/keywords/fas-ligand","display_name":"Fas ligand","score":0.9940000176429749},{"id":"https://openalex.org/keywords/immune-evasion","display_name":"immune evasion","score":0.7770000100135803},{"id":"https://openalex.org/keywords/immunosurveillance","display_name":"immune surveillance","score":0.9150000214576721},{"id":"https://openalex.org/keywords/apoptosis-resistance","display_name":"apoptosis resistance","score":0.8289999961853027},{"id":"https://openalex.org/keywords/t-cell-mediated-killing","display_name":"T cell-mediated killing","score":0.6779999732971191},{"id":"https://openalex.org/keywords/tumor-escape-mechanisms","display_name":"tumor escape mechanisms","score":0.6110000014305115},{"id":"https://openalex.org/keywords/fas-mediated-apoptosis","display_name":"Fas-mediated apoptosis","score":0.43700000643730164}],"concepts":[{"id":"https://openalex.org/C66008609","wikidata":"https://www.wikidata.org/wiki/Q14866113","display_name":"Fas ligand","level":4,"score":0.8326066136360168},{"id":"https://openalex.org/C3031857","wikidata":"https://www.wikidata.org/wiki/Q1649375","display_name":"Fas receptor","level":4,"score":0.7052639722824097},{"id":"https://openalex.org/C2780210213","wikidata":"https://www.wikidata.org/wiki/Q212961","display_name":"Pancreatic cancer","level":3,"score":0.6030299663543701},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.585931122303009},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5801545977592468},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5158516764640808},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4932648539543152},{"id":"https://openalex.org/C179464577","wikidata":"https://www.wikidata.org/wiki/Q1632589","display_name":"Jurkat cells","level":4,"score":0.4822005033493042},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.471723735332489},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.47070786356925964},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.43087148666381836},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.23505747318267822},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22954651713371277},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.19036102294921875},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17024999856948853},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005434","descriptor_name":"Flow Cytometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007157","descriptor_name":"Immunologic Surveillance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010179","descriptor_name":"Pancreas","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D010190","descriptor_name":"Pancreatic Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D010190","descriptor_name":"Pancreatic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010190","descriptor_name":"Pancreatic Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015151","descriptor_name":"Immunoblotting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019014","descriptor_name":"fas Receptor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019014","descriptor_name":"fas Receptor","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D053222","descriptor_name":"Fas Ligand Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/s0039-6060(99)70291-6","doi":"https://doi.org/10.1016/s0039-6060(99)70291-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0039-6060(99)70291-6","pdf_url":null,"source":{"id":"https://openalex.org/S4210173306","display_name":"Surgery","issn_l":"0039-6060","issn":["0039-6060","1532-7361"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgery","raw_type":"journal-article"},{"id":"doi:10.1067/msy.2099.93570","doi":"https://doi.org/10.1067/msy.2099.93570","is_oa":false,"landing_page_url":"https://doi.org/10.1067/msy.2099.93570","pdf_url":null,"source":{"id":"https://openalex.org/S4210173306","display_name":"Surgery","issn_l":"0039-6060","issn":["0039-6060","1532-7361"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgery","raw_type":"journal-article"},{"id":"pmid:9889801","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9889801","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgery","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2458608261","display_name":null,"funder_award_id":"R01 CA 606662","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G489421352","display_name":"Advanced Training in Surgical Oncology","funder_award_id":"T32CA009535","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G7400609524","display_name":null,"funder_award_id":"R01 CA45854","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1485742966","https://openalex.org/W1502472010","https://openalex.org/W1517945724","https://openalex.org/W1542886054","https://openalex.org/W1546319410","https://openalex.org/W1556149314","https://openalex.org/W1575217068","https://openalex.org/W1581932048","https://openalex.org/W1976692354","https://openalex.org/W1978416272","https://openalex.org/W1980516488","https://openalex.org/W1986785442","https://openalex.org/W1992307473","https://openalex.org/W1995124037","https://openalex.org/W2002503549","https://openalex.org/W2016198585","https://openalex.org/W2025260365","https://openalex.org/W2030005722","https://openalex.org/W2034295054","https://openalex.org/W2045049074","https://openalex.org/W2045068005","https://openalex.org/W2045796964","https://openalex.org/W2047056744","https://openalex.org/W2054922338","https://openalex.org/W2056010217","https://openalex.org/W2056033102","https://openalex.org/W2075809552","https://openalex.org/W2076656122","https://openalex.org/W2076772718","https://openalex.org/W2084105573","https://openalex.org/W2085173450","https://openalex.org/W2095041443","https://openalex.org/W2102632492","https://openalex.org/W2106567289","https://openalex.org/W2111181668","https://openalex.org/W2116045049","https://openalex.org/W2124534310","https://openalex.org/W2129971278","https://openalex.org/W2143996326","https://openalex.org/W2146839556","https://openalex.org/W2154063020","https://openalex.org/W2166487006","https://openalex.org/W2168747001","https://openalex.org/W2400630459","https://openalex.org/W6712948149"],"related_works":["https://openalex.org/W1989491352","https://openalex.org/W2147754540","https://openalex.org/W1993225663","https://openalex.org/W1492250691","https://openalex.org/W2468678546","https://openalex.org/W2083237227","https://openalex.org/W1993085816","https://openalex.org/W2054359894","https://openalex.org/W1994159422","https://openalex.org/W2044356413"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}