{"id":"https://openalex.org/W2011948787","doi":"https://doi.org/10.1016/j.yexcr.2010.11.018","title":"KSR1 is a functional protein kinase capable of serine autophosphorylation and direct phosphorylation of MEK1","display_name":"KSR1 is a functional protein kinase capable of serine autophosphorylation and direct phosphorylation of MEK1","publication_year":2010,"publication_date":"2010-12-08","ids":{"openalex":"https://openalex.org/W2011948787","doi":"https://doi.org/10.1016/j.yexcr.2010.11.018","mag":"2011948787","pmid":"https://pubmed.ncbi.nlm.nih.gov/21144847","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3038243"},"language":"en","primary_location":{"id":"doi:10.1016/j.yexcr.2010.11.018","doi":"https://doi.org/10.1016/j.yexcr.2010.11.018","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.yexcr.2010.11.018","pdf_url":null,"source":{"id":"https://openalex.org/S132505712","display_name":"Experimental Cell Research","issn_l":"0014-4827","issn":["0014-4827","1090-2422"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Cell Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3038243","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036202498","display_name":"Jeremy A. Goettel","orcid":"https://orcid.org/0000-0002-0749-2357","observed_orcids":["https://orcid.org/0000-0002-0749-2357"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeremy A. Goettel","raw_affiliation_strings":["Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000893477","display_name":"Dongchun Liang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dongchun Liang","raw_affiliation_strings":["Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University School of Medicine, Nashville, TN 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University School of Medicine, Nashville, TN 37232, USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070014944","display_name":"Valda C. Hilliard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Valda C. Hilliard","raw_affiliation_strings":["Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028529598","display_name":"Karen L. Edelblum","orcid":"https://orcid.org/0000-0001-8288-4898","observed_orcids":["https://orcid.org/0000-0001-8288-4898"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karen L. Edelblum","raw_affiliation_strings":["Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014273811","display_name":"Matthew R. Broadus","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew R. Broadus","raw_affiliation_strings":["Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066662711","display_name":"Kathleen L. Gould","orcid":"https://orcid.org/0000-0002-3810-4070","observed_orcids":["https://orcid.org/0000-0002-3810-4070","https://orcid.org/0000-0002-2981-269X"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kathleen L. Gould","raw_affiliation_strings":["Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA","Howard Hughes Medical Institute, Vanderbilt University School of Medicine, Nashville, TN 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]},{"raw_affiliation_string":"Howard Hughes Medical Institute, Vanderbilt University School of Medicine, Nashville, TN 37232, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016617544","display_name":"Steven K. Hanks","orcid":"https://orcid.org/0000-0003-1414-5529","observed_orcids":["https://orcid.org/0000-0003-1414-5529"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven K. Hanks","raw_affiliation_strings":["Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014815275","display_name":"D. Brent Polk","orcid":"https://orcid.org/0000-0001-6680-1554","observed_orcids":["https://orcid.org/0000-0001-6680-1554"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"D. Brent Polk","raw_affiliation_strings":["Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA","Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University School of Medicine, Nashville, TN 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University School of Medicine, Nashville, TN 37232, USA","institution_ids":["https://openalex.org/I200719446"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5014815275"],"corresponding_institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"],"apc_list":{"value":3270,"currency":"USD","value_usd":3270},"apc_paid":null,"fwci":1.1718,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.75580181,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"317","issue":"4","first_page":"452","last_page":"463"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.7797999978065491,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.7797999978065491,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11533","display_name":"Melanoma and MAPK Pathways","score":0.19979999959468842,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12104","display_name":"Protein Tyrosine Phosphatases","score":0.014399999752640724,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ksr1","display_name":"KSR1","score":0.9959999918937683},{"id":"https://openalex.org/keywords/protein-kinases","display_name":"protein kinases","score":0.43299999833106995},{"id":"https://openalex.org/keywords/mek1-phosphorylation","display_name":"MEK1 phosphorylation","score":0.9679999947547913},{"id":"https://openalex.org/keywords/mapk-erk-pathway","display_name":"MAPK/ERK pathway","score":0.875},{"id":"https://openalex.org/keywords/mapk-erk-kinase","display_name":"MAPK/ERK kinase","score":0.7879999876022339},{"id":"https://openalex.org/keywords/tnf-alpha-induced-apoptosis","display_name":"TNF-induced apoptosis","score":0.7739999890327454},{"id":"https://openalex.org/keywords/cell-survival-signaling","display_name":"cell survival signaling","score":0.7540000081062317},{"id":"https://openalex.org/keywords/colonic-epithelial-cells","display_name":"colonic epithelial cells","score":0.9729999899864197}],"concepts":[{"id":"https://openalex.org/C90934575","wikidata":"https://www.wikidata.org/wiki/Q6593810","display_name":"Mitogen-activated protein kinase kinase","level":4,"score":0.7519888877868652},{"id":"https://openalex.org/C150109051","wikidata":"https://www.wikidata.org/wiki/Q3630494","display_name":"Autophosphorylation","level":4,"score":0.7179610729217529},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.716781735420227},{"id":"https://openalex.org/C137361374","wikidata":"https://www.wikidata.org/wiki/Q6714442","display_name":"MAP kinase kinase kinase","level":4,"score":0.7064371109008789},{"id":"https://openalex.org/C159479382","wikidata":"https://www.wikidata.org/wiki/Q18030801","display_name":"MAP2K7","level":5,"score":0.6902979612350464},{"id":"https://openalex.org/C59143045","wikidata":"https://www.wikidata.org/wiki/Q15314942","display_name":"Cyclin-dependent kinase 9","level":5,"score":0.6791369318962097},{"id":"https://openalex.org/C82495950","wikidata":"https://www.wikidata.org/wiki/Q14911732","display_name":"Cyclin-dependent kinase 2","level":4,"score":0.6686336994171143},{"id":"https://openalex.org/C124160383","wikidata":"https://www.wikidata.org/wiki/Q14914383","display_name":"ASK1","level":5,"score":0.65276038646698},{"id":"https://openalex.org/C99405784","wikidata":"https://www.wikidata.org/wiki/Q410434","display_name":"c-Raf","level":5,"score":0.5771057605743408},{"id":"https://openalex.org/C51853150","wikidata":"https://www.wikidata.org/wiki/Q14911754","display_name":"Cyclin-dependent kinase 4","level":5,"score":0.5681945085525513},{"id":"https://openalex.org/C97029542","wikidata":"https://www.wikidata.org/wiki/Q281417","display_name":"Protein kinase A","level":3,"score":0.5233249664306641},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.47877299785614014},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4528842270374298},{"id":"https://openalex.org/C163035849","wikidata":"https://www.wikidata.org/wiki/Q15326910","display_name":"MAPK14","level":5,"score":0.4457726776599884},{"id":"https://openalex.org/C161238802","wikidata":"https://www.wikidata.org/wiki/Q14905690","display_name":"Protein kinase R","level":5,"score":0.44501176476478577},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3448645770549774},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.33029186725616455}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002384","descriptor_name":"Catalysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003106","descriptor_name":"Colon","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010766","descriptor_name":"Phosphorylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011494","descriptor_name":"Protein Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012694","descriptor_name":"Serine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013379","descriptor_name":"Substrate Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D029968","descriptor_name":"Escherichia coli Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D048369","descriptor_name":"MAP Kinase Kinase 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.yexcr.2010.11.018","doi":"https://doi.org/10.1016/j.yexcr.2010.11.018","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.yexcr.2010.11.018","pdf_url":null,"source":{"id":"https://openalex.org/S132505712","display_name":"Experimental Cell Research","issn_l":"0014-4827","issn":["0014-4827","1090-2422"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Cell Research","raw_type":"journal-article"},{"id":"pmid:21144847","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21144847","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental cell research","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2285993","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3038243","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3038243","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3038243","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Exp Cell Res","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2285993","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3038243","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":0.4000000059604645,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G101158308","display_name":"Cytokine regulation of intestinal epithelial restitution","funder_award_id":"R01DK056008","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G252522409","display_name":null,"funder_award_id":"GM 068786","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G2901029833","display_name":"Mechanisms of KSR regulation in intestinal cell survival","funder_award_id":"R01DK066176","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G4737038574","display_name":"BRCA1 and estrogen signaling during tumorigenesis","funder_award_id":"Z01DK056008","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G6843006214","display_name":null,"funder_award_id":"DK 066176","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G6931066848","display_name":"Regulation and function of the Clp 1p protein phosphatase","funder_award_id":"R01GM068786","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000880213","display_name":"Biochemical and Chemical Training for Cancer Research","funder_award_id":"T32CA009582","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320306082","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":71,"referenced_works":["https://openalex.org/W80640741","https://openalex.org/W137936598","https://openalex.org/W1002836587","https://openalex.org/W1486015064","https://openalex.org/W1520176015","https://openalex.org/W1577992990","https://openalex.org/W1582277695","https://openalex.org/W1593223362","https://openalex.org/W1602867448","https://openalex.org/W1656231611","https://openalex.org/W1658971169","https://openalex.org/W1827897670","https://openalex.org/W1850765736","https://openalex.org/W1858320063","https://openalex.org/W1875580551","https://openalex.org/W1965295110","https://openalex.org/W1972812612","https://openalex.org/W1978522292","https://openalex.org/W1985309852","https://openalex.org/W1986229370","https://openalex.org/W1986310093","https://openalex.org/W1988588903","https://openalex.org/W1993552956","https://openalex.org/W2005026826","https://openalex.org/W2007665864","https://openalex.org/W2008333101","https://openalex.org/W2011184275","https://openalex.org/W2015927126","https://openalex.org/W2016117582","https://openalex.org/W2016910304","https://openalex.org/W2017086844","https://openalex.org/W2017194364","https://openalex.org/W2020257412","https://openalex.org/W2026707666","https://openalex.org/W2034981642","https://openalex.org/W2037838528","https://openalex.org/W2043775652","https://openalex.org/W2049355403","https://openalex.org/W2052122921","https://openalex.org/W2054159403","https://openalex.org/W2057392977","https://openalex.org/W2060840912","https://openalex.org/W2068461173","https://openalex.org/W2071447700","https://openalex.org/W2074303585","https://openalex.org/W2076666771","https://openalex.org/W2077086907","https://openalex.org/W2079024949","https://openalex.org/W2079156404","https://openalex.org/W2079948123","https://openalex.org/W2081599782","https://openalex.org/W2086419819","https://openalex.org/W2090979423","https://openalex.org/W2097246438","https://openalex.org/W2099267053","https://openalex.org/W2100245710","https://openalex.org/W2101417059","https://openalex.org/W2101796805","https://openalex.org/W2103901567","https://openalex.org/W2112879240","https://openalex.org/W2117488654","https://openalex.org/W2124356134","https://openalex.org/W2128230250","https://openalex.org/W2149242879","https://openalex.org/W2151542719","https://openalex.org/W2153084734","https://openalex.org/W2156433178","https://openalex.org/W2164967269","https://openalex.org/W2165976417","https://openalex.org/W2166624257","https://openalex.org/W2299322909"],"related_works":["https://openalex.org/W2049809410","https://openalex.org/W7098868895","https://openalex.org/W1992420595","https://openalex.org/W2186593287","https://openalex.org/W2056924558","https://openalex.org/W2086419819","https://openalex.org/W2099267053","https://openalex.org/W2049355403","https://openalex.org/W2079618910","https://openalex.org/W1967519664"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
