{"id":"https://openalex.org/W2011744761","doi":"https://doi.org/10.1016/0161-5890(94)90019-1","title":"Peptide binding to the most frequent HLA-A class I alleles measured by quantitative molecular binding assays","display_name":"Peptide binding to the most frequent HLA-A class I alleles measured by quantitative molecular binding assays","publication_year":1994,"publication_date":"1994-08-01","ids":{"openalex":"https://openalex.org/W2011744761","doi":"https://doi.org/10.1016/0161-5890(94)90019-1","mag":"2011744761","pmid":"https://pubmed.ncbi.nlm.nih.gov/8047072"},"language":"en","primary_location":{"id":"doi:10.1016/0161-5890(94)90019-1","doi":"https://doi.org/10.1016/0161-5890(94)90019-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0161-5890(94)90019-1","pdf_url":null,"source":{"id":"https://openalex.org/S92126311","display_name":"Molecular Immunology","issn_l":"0161-5890","issn":["0161-5890","1872-9142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010966529","display_name":"Alessandro Sette","orcid":"https://orcid.org/0000-0001-7013-2250","observed_orcids":["https://orcid.org/0000-0001-7013-2250"]},"institutions":[{"id":"https://openalex.org/I95746587","display_name":"Cytel (United States)","ror":"https://ror.org/01ftkxq60","country_code":"US","type":"company","lineage":["https://openalex.org/I95746587"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Alessandro Sette","raw_affiliation_strings":["Cytel, San Diego, CA 92121"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cytel, San Diego, CA 92121","institution_ids":["https://openalex.org/I95746587"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037285448","display_name":"John Sidney","orcid":"https://orcid.org/0000-0002-0987-405X","observed_orcids":["https://orcid.org/0000-0002-0987-405X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John Sidney","raw_affiliation_strings":["Cytel, 3525 John Hopkins Court, San Diego, CA 92121 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cytel, 3525 John Hopkins Court, San Diego, CA 92121 U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011114200","display_name":"Marie\u2010France del Guercio","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marie-France del Guercio","raw_affiliation_strings":["Cytel, 3525 John Hopkins Court, San Diego, CA 92121 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cytel, 3525 John Hopkins Court, San Diego, CA 92121 U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041720192","display_name":"Scott Southwood","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Scott Southwood","raw_affiliation_strings":["Cytel, 3525 John Hopkins Court, San Diego, CA 92121 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cytel, 3525 John Hopkins Court, San Diego, CA 92121 U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105259667","display_name":"J Ruppert","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J\u00f6rg Ruppert","raw_affiliation_strings":["Cytel, 3525 John Hopkins Court, San Diego, CA 92121 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cytel, 3525 John Hopkins Court, San Diego, CA 92121 U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107344760","display_name":"Carol M. Dahlberg","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carol Dahlberg","raw_affiliation_strings":["Cytel, 3525 John Hopkins Court, San Diego, CA 92121 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cytel, 3525 John Hopkins Court, San Diego, CA 92121 U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110101301","display_name":"Howard M. Grey","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Howard M. Grey","raw_affiliation_strings":["Cytel, 3525 John Hopkins Court, San Diego, CA 92121 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cytel, 3525 John Hopkins Court, San Diego, CA 92121 U.S.A","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111759012","display_name":"Ralph T. Kubo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ralph T. Kubo","raw_affiliation_strings":["Cytel, 3525 John Hopkins Court, San Diego, CA 92121 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cytel, 3525 John Hopkins Court, San Diego, CA 92121 U.S.A","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5010966529"],"corresponding_institution_ids":["https://openalex.org/I95746587"],"apc_list":{"value":3340,"currency":"USD","value_usd":3340},"apc_paid":null,"fwci":4.2466,"has_fulltext":false,"cited_by_count":226,"citation_normalized_percentile":{"value":0.95617782,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":92,"max":99},"biblio":{"volume":"31","issue":"11","first_page":"813","last_page":"822"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.005900000222027302,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/binding-affinity","display_name":"binding affinity","score":0.7900000214576721},{"id":"https://openalex.org/keywords/hla-a1","display_name":"HLA-A1","score":0.6930000185966492},{"id":"https://openalex.org/keywords/hla-a2","display_name":"HLA-A2","score":0.9190000295639038},{"id":"https://openalex.org/keywords/hla-a3","display_name":"HLA-A3","score":0.9340000152587891},{"id":"https://openalex.org/keywords/hla-a11","display_name":"HLA-A11","score":0.9929999709129333},{"id":"https://openalex.org/keywords/hla-a24","display_name":"HLA-A24","score":0.9990000128746033},{"id":"https://openalex.org/keywords/peptide-length","display_name":"peptide length","score":0.4819999933242798},{"id":"https://openalex.org/keywords/radiolabeled-peptides","display_name":"radiolabeled peptides","score":0.5580000281333923},{"id":"https://openalex.org/keywords/ebv-transformed-b-cells","display_name":"EBV-transformed B cells","score":0.7620000243186951}],"concepts":[{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.7769956588745117},{"id":"https://openalex.org/C188280979","wikidata":"https://www.wikidata.org/wiki/Q911125","display_name":"Human leukocyte antigen","level":3,"score":0.672980546951294},{"id":"https://openalex.org/C170627219","wikidata":"https://www.wikidata.org/wiki/Q13218497","display_name":"MHC class I","level":4,"score":0.6042287945747375},{"id":"https://openalex.org/C197695756","wikidata":"https://www.wikidata.org/wiki/Q1750372","display_name":"MHC restriction","level":5,"score":0.5737661123275757},{"id":"https://openalex.org/C207936829","wikidata":"https://www.wikidata.org/wiki/Q423163","display_name":"Major histocompatibility complex","level":3,"score":0.5726833343505859},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5389654636383057},{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.5158966779708862},{"id":"https://openalex.org/C2778814158","wikidata":"https://www.wikidata.org/wiki/Q959350","display_name":"MHC class II","level":4,"score":0.49982404708862305},{"id":"https://openalex.org/C85196483","wikidata":"https://www.wikidata.org/wiki/Q6545857","display_name":"Ligand binding assay","level":3,"score":0.4512093663215637},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.4118277132511139},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.40902990102767944},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.39133507013320923},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3609970808029175},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3402695953845978},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.30810117721557617},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14487308263778687},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.07555705308914185}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002461","descriptor_name":"Cell Line, Transformed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015234","descriptor_name":"HLA-A Antigens","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015234","descriptor_name":"HLA-A Antigens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0161-5890(94)90019-1","doi":"https://doi.org/10.1016/0161-5890(94)90019-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0161-5890(94)90019-1","pdf_url":null,"source":{"id":"https://openalex.org/S92126311","display_name":"Molecular Immunology","issn_l":"0161-5890","issn":["0161-5890","1872-9142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Immunology","raw_type":"journal-article"},{"id":"pmid:8047072","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8047072","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular immunology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.4000000059604645,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G7959173292","display_name":"MOLECULAR EVENTS IN ANTIGEN RECOGNITION","funder_award_id":"R01AI018634","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":81,"referenced_works":["https://openalex.org/W1500421682","https://openalex.org/W1509190187","https://openalex.org/W1519407700","https://openalex.org/W1523002822","https://openalex.org/W1528253449","https://openalex.org/W1529365470","https://openalex.org/W1544824666","https://openalex.org/W1565620407","https://openalex.org/W1579412383","https://openalex.org/W1585454606","https://openalex.org/W1615479881","https://openalex.org/W1646416275","https://openalex.org/W1682946614","https://openalex.org/W1817144267","https://openalex.org/W1967582433","https://openalex.org/W1969057879","https://openalex.org/W1971302107","https://openalex.org/W1972466190","https://openalex.org/W1976296968","https://openalex.org/W1980039341","https://openalex.org/W1986070284","https://openalex.org/W1986645576","https://openalex.org/W1987752224","https://openalex.org/W1995232552","https://openalex.org/W1995377723","https://openalex.org/W1996567630","https://openalex.org/W2000919244","https://openalex.org/W2001852133","https://openalex.org/W2003828446","https://openalex.org/W2006629564","https://openalex.org/W2008774884","https://openalex.org/W2011848545","https://openalex.org/W2012201233","https://openalex.org/W2019993505","https://openalex.org/W2022995076","https://openalex.org/W2023651173","https://openalex.org/W2026970642","https://openalex.org/W2031101268","https://openalex.org/W2031962597","https://openalex.org/W2034298592","https://openalex.org/W2034841844","https://openalex.org/W2035487181","https://openalex.org/W2035620936","https://openalex.org/W2037260212","https://openalex.org/W2045377848","https://openalex.org/W2051140392","https://openalex.org/W2063580217","https://openalex.org/W2063841466","https://openalex.org/W2066475494","https://openalex.org/W2073560443","https://openalex.org/W2076058809","https://openalex.org/W2077861376","https://openalex.org/W2082173837","https://openalex.org/W2085450869","https://openalex.org/W2089689490","https://openalex.org/W2099028937","https://openalex.org/W2101305284","https://openalex.org/W2107971340","https://openalex.org/W2108142790","https://openalex.org/W2126375281","https://openalex.org/W2126467497","https://openalex.org/W2132612515","https://openalex.org/W2141988411","https://openalex.org/W2142077098","https://openalex.org/W2148368831","https://openalex.org/W2149167278","https://openalex.org/W2150371745","https://openalex.org/W2153918116","https://openalex.org/W2155599296","https://openalex.org/W2160302934","https://openalex.org/W2169643581","https://openalex.org/W2399965080","https://openalex.org/W2430584636","https://openalex.org/W6644458596","https://openalex.org/W6644946255","https://openalex.org/W6648928678","https://openalex.org/W6656237788","https://openalex.org/W6656293573","https://openalex.org/W6667016903","https://openalex.org/W6674753749","https://openalex.org/W6682312542"],"related_works":["https://openalex.org/W2001759740","https://openalex.org/W243283527","https://openalex.org/W1805141485","https://openalex.org/W3194897096","https://openalex.org/W2123434474","https://openalex.org/W2027795203","https://openalex.org/W2170937875","https://openalex.org/W7095114701","https://openalex.org/W1973704411","https://openalex.org/W1646416275"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}